Published in PLoS One on October 05, 2016
Multiplex genome engineering using CRISPR/Cas systems. Science (2013) 55.53
Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J Cell Biol (1975) 8.68
Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone. Endocrinology (1968) 4.12
Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?. Ann N Y Acad Sci (2009) 3.27
Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science (2006) 2.24
Acromegaly pathogenesis and treatment. J Clin Invest (2009) 2.19
Production of both prolactin and growth hormone by clonal strains of rat pituitary tumor cells. Differential effects of hydrocortisone and tissue extracts. J Cell Biol (1970) 2.00
Does growth hormone cause cancer? Clin Endocrinol (Oxf) (2006) 1.86
High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas. Eur J Endocrinol (2011) 1.69
Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families. J Clin Endocrinol Metab (2007) 1.53
The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas. J Clin Endocrinol Metab (2008) 1.42
Familial isolated pituitary adenomas (FIPA) and the pituitary adenoma predisposition due to mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene. Endocr Rev (2013) 1.40
Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study. J Clin Endocrinol Metab (2010) 1.24
Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression. Cancer Res (2006) 1.24
Octreotide and the mTOR inhibitor RAD001 (everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumour cell Line. Neuroendocrinology (2007) 1.11
Germline AIP mutations in apparently sporadic pituitary adenomas: prevalence in a prospective single-center cohort of 443 patients. J Clin Endocrinol Metab (2012) 1.10
Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications. Endocr Relat Cancer (2009) 1.03
Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway. J Clin Endocrinol Metab (2012) 0.98
Structure of the TPR domain of AIP: lack of client protein interaction with the C-terminal α-7 helix of the TPR domain of AIP is sufficient for pituitary adenoma predisposition. PLoS One (2012) 0.96
Mice with inactivation of aryl hydrocarbon receptor-interacting protein (Aip) display complete penetrance of pituitary adenomas with aberrant ARNT expression. Am J Pathol (2010) 0.94
Clinical, genetic and molecular characterization of patients with familial isolated pituitary adenomas (FIPA). Trends Endocrinol Metab (2010) 0.94
ZAC1 target genes and pituitary tumorigenesis. Mol Cell Endocrinol (2010) 0.93
Somatostatin activation of mitogen-activated protein kinase via somatostatin receptor 1 (SSTR1). Mol Endocrinol (1999) 0.91
Cultures of GH3 cells are functionally heterogeneous: thyrotropin-releasing hormone, estradiol and cortisol cause reciprocal shifts in the proportions of growth hormone and prolactin secretors. Endocrinology (1985) 0.90
Diabetes in acromegaly, prevalence, risk factors, and evolution: data from the French Acromegaly Registry. Eur J Endocrinol (2011) 0.89
Inhibition of 5alpha-reductase enhances testosterone-induced expression of U19/Eaf2 tumor suppressor during the regrowth of LNCaP xenograft tumor in nude mice. Prostate (2010) 0.87
Exendin-4, a GLP-1 receptor agonist, attenuates prostate cancer growth. Diabetes (2014) 0.86
AIP inactivation leads to pituitary tumorigenesis through defective Gαi-cAMP signaling. Oncogene (2014) 0.85
Tumor ZAC1 expression is associated with the response to somatostatin analog therapy in patients with acromegaly. Int J Cancer (2009) 0.84
Steroidogenic factor 1/adrenal 4 binding protein transforms human bone marrow mesenchymal cells into steroidogenic cells. J Mol Endocrinol (2007) 0.84
STAT3 upregulation in pituitary somatotroph adenomas induces growth hormone hypersecretion. J Clin Invest (2015) 0.81
Factors predicting pasireotide responsiveness in somatotroph pituitary adenomas resistant to first-generation somatostatin analogues: an immunohistochemical study. Eur J Endocrinol (2015) 0.80
Aip regulates cAMP signalling and GH secretion in GH3 cells. Endocr Relat Cancer (2013) 0.79
GH3 cell secretion of growth hormone and prolactin increases spontaneously during perifusion. In Vitro Cell Dev Biol (1987) 0.79
A novel C-terminal nonsense mutation, Q315X, of the aryl hydrocarbon receptor-interacting protein gene in a Japanese familial isolated pituitary adenoma family. Endocr Pathol (2014) 0.78
Effect of octreotide on circulating IGF-I chromatographic profile: evidence for an inhibitory action on the formation of the 150-kDa ternary complex. Clin Endocrinol (Oxf) (1995) 0.77
Multiple regulation of adenylyl cyclase activity by G-protein coupled receptors in human foetal lung fibroblasts. Regul Pept (2000) 0.76