Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification.

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Published in J Virol on November 28, 2016

Authors

Ashley Sobel Leonard1, Micah T McClain2, Gavin J D Smith3, David E Wentworth4, Rebecca A Halpin4, Xudong Lin4, Amy Ransier4, Timothy B Stockwell4, Suman R Das4, Anthony S Gilbert5, Robert Lambkin-Williams5, Geoffrey S Ginsburg2, Christopher W Woods2, Katia Koelle6

Author Affiliations

1: Department of Biology, Duke University, Durham, North Carolina, USA Ashley.Sobel@duke.edu.
2: Duke Center for Applied Genomics and Precision Medicine, Durham, North Carolina, USA.
3: Laboratory of Virus Evolution, Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
4: J. Craig Venter Institute, Rockville, Maryland, USA.
5: hVIVO, London, United Kingdom.
6: Department of Biology, Duke University, Durham, North Carolina, USA.

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