Published in Pharmaceuticals (Basel) on October 24, 2011
Sticky overhangs enhance siRNA-mediated gene silencing. Proc Natl Acad Sci U S A (2007) 1.68
Drug delivery trends in clinical trials and translational medicine: challenges and opportunities in the delivery of nucleic acid-based therapeutics. J Pharm Sci (2011) 1.24
Charge-reversal amphiphiles for gene delivery. J Am Chem Soc (2004) 1.21
Synthesis, activity, and structure--activity relationship studies of novel cationic lipids for DNA transfer. J Med Chem (1998) 1.13
Artificial viruses and their application to gene delivery. Size-controlled gene coating with glycocluster nanoparticles. J Am Chem Soc (2003) 1.09
Steric control over hydrogen bonding in crystalline organic solids: a structural study of N,N'-dialkylthioureas. Chemistry (2005) 1.08
Factors influencing the retention and chemical stability of poly(ethylene glycol)-lipid conjugates incorporated into large unilamellar vesicles. Biochim Biophys Acta (1994) 1.03
Non-viral vectors for cancer therapy. Cancer Sci (2006) 0.99
Thiourea isosteres as anion receptors and transmembrane transporters. Chem Commun (Camb) (2011) 0.99
Trends in lipoplex physical properties dependent on cationic lipid structure, vehicle and complexation procedure do not correlate with biological activity. Nucleic Acids Res (2001) 0.95
Physicochemical optimisation of plasmid delivery by cationic lipids. J Gene Med (2004) 0.93
Nucleic acid complexing glycosyl nucleoside-based amphiphile. Bioconjug Chem (2005) 0.90
Tripodal transmembrane transporters for bicarbonate. Chem Commun (Camb) (2010) 0.89
Supramolecular assemblies of DNA with neutral nucleoside amphiphiles. Chem Commun (Camb) (2005) 0.87
Anionic polymers for decreased toxicity and enhanced in vivo delivery of siRNA complexed with cationic liposomes. J Control Release (2011) 0.86
The effect of extensible PEG tethers on shielding between grafted thermo-responsive polymer chains and integrin-RGD binding. Biomaterials (2008) 0.85
Cationic siRNAs provide carrier-free gene silencing in animal cells. J Am Chem Soc (2009) 0.85
Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery. Biomaterials (2011) 0.85
How to make siRNA lipoplexes efficient? Add a DNA cargo. Biochim Biophys Acta (2009) 0.84
Design, synthesis, and evaluation of enhanced DNA binding new lipopolythioureas. Bioconjug Chem (2006) 0.84
Urea-, thiourea-, and guanidine-linked glycooligomers as phosphate binders in water. J Org Chem (2006) 0.83
Lipopolythioureas: a new non-cationic system for gene transfer. Bioconjug Chem (2007) 0.82
Anionic polyethyleneglycol lipids added to cationic lipoplexes increase their plasmatic circulation time. J Control Release (2003) 0.82
Cationic lipids for transfection. Curr Med Chem (2003) 0.82
The spherulites(TM): a promising carrier for oligonucleotide delivery. Nucleic Acids Res (2000) 0.82
Current prospects for gene therapy of cystic fibrosis. Curr Opin Pharmacol (2006) 0.80
Plasmid-mediated gene therapy for cardiovascular disease. Cardiovasc Res (2011) 0.80
Cationic and anionic lipoplexes inhibit gene transfection by electroporation in vivo. J Gene Med (2010) 0.79
Neutral postgrafted colloidal particles for gene delivery. Bioconjug Chem (2005) 0.79
DNA complexing lipopolythiourea. Bioconjug Chem (2004) 0.79
Polycationic amphiphilic cyclodextrins for gene delivery: synthesis and effect of structural modifications on plasmid DNA complex stability, cytotoxicity, and gene expression. Chemistry (2009) 0.79
Tailoring beta-cyclodextrin for DNA complexation and delivery by homogeneous functionalization at the secondary face. Org Lett (2008) 0.78
Real-time imaging of gene delivery and expression with DNA nanoparticle technologies. Methods Mol Biol (2009) 0.78
Comparative gene transfer between cationic and thiourea lipoplexes. J Gene Med (2010) 0.77
What role can chemistry play in cationic liposome-based gene therapy research today? Adv Genet (2005) 0.77
Propidium iodide and PicoGreen as dyes for the DNA fluorescence correlation spectroscopy measurements. J Fluoresc (2005) 0.77
A single thiourea group is not enough to get stable thiourea lipoplexes. Bioorg Med Chem (2008) 0.77
Protonation of lipids impacts the supramolecular and biological properties of their self-assembly. Langmuir (2011) 0.77
Iminothiol/thiourea tautomeric equilibrium in thiourea lipids impacts DNA compaction by inducing a cationic nucleation for complex assembly. Biophys Chem (2009) 0.76
Lipopolythiourea/DNA interaction: a biophysical study. Biophys Chem (2010) 0.76
Rational design of cationic cyclooligosaccharides as efficient gene delivery systems. Chem Commun (Camb) (2008) 0.76
Lipopolythiourea transfecting agents: lysine thiourea derivatives. Bioconjug Chem (2007) 0.76