Significant weight loss following clozapine use, how is it possible? A case report and review of published cases and literature relevant to the subject.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27721972)

Published in Ther Adv Psychopharmacol on May 31, 2016

Authors

Tongeji E Tungaraza1

Author Affiliations

1: Partnerships in Care, Beverley House, 527-529 City Road, Birmingham B17 8LL, UK.

Articles cited by this

Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med (2005) 28.99

Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch Gen Psychiatry (1988) 12.39

Schizophrenia: a concise overview of incidence, prevalence, and mortality. Epidemiol Rev (2008) 4.43

Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis. Schizophr Res (2010) 3.26

Randomized controlled trial of effect of prescription of clozapine versus other second-generation antipsychotic drugs in resistant schizophrenia. Schizophr Bull (2006) 2.71

The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophr Bull (1999) 2.10

Evidence of clozapine's effectiveness in schizophrenia: a systematic review and meta-analysis of randomized trials. Am J Psychiatry (1999) 1.64

Duration of a clozapine trial in neuroleptic-resistant schizophrenia. Arch Gen Psychiatry (1989) 1.48

Weight management program for treatment-emergent weight gain in olanzapine-treated patients with schizophrenia or schizoaffective disorder: A 12-week randomized controlled clinical trial. J Clin Psychiatry (2006) 1.33

Evaluation of treatment-resistant schizophrenia. Schizophr Bull (1997) 1.31

Cognitive behavioural therapy for weight gain associated with antipsychotic drugs. Schizophr Res (2007) 1.11

Antipsychotic-induced weight gain and therapeutic response: a differential association. J Clin Psychopharmacol (2002) 1.10

Systematic Review and Meta-analysis of Pharmacological Interventions for Weight Gain from Antipsychotics and Mood Stabilizers. Curr Psychiatry Rev (2012) 1.08

Neural basis for the ability of atypical antipsychotic drugs to improve cognition in schizophrenia. Front Behav Neurosci (2013) 1.01

A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia. Neuropsychopharmacology (2010) 0.99

Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. J Psychiatry Neurosci (2007) 0.99

Comparison of cognitive performances during a placebo period and an atypical antipsychotic treatment period in schizophrenia: critical examination of confounds. Neuropsychopharmacology (2003) 0.97

Is clozapine-aripiprazole combination a useful regime in the management of treatment-resistant schizophrenia? J Psychopharmacol (2006) 0.95

The association between weight change and symptom reduction in the CATIE schizophrenia trial. Schizophr Res (2011) 0.95

Addressing the unmet needs of patients with persistent negative symptoms of schizophrenia: emerging pharmacological treatment options. Neuropsychiatr Dis Treat (2014) 0.93

Pharmacogenetic Aspects of Antipsychotic Drug-induced Weight Gain - A Critical Review. Clin Psychopharmacol Neurosci (2012) 0.89

Pharmacogenetics of antipsychotics: recent progress and methodological issues. Expert Opin Drug Metab Toxicol (2012) 0.88

Classics in chemical neuroscience: clozapine. ACS Chem Neurosci (2013) 0.88

Clozapine safety, 35 years later. Curr Drug Saf (2011) 0.87

Weight gain associated with neuroleptic medication: a review. Schizophr Bull (1995) 0.86

Atypical antipsychotics and the neural regulation of food intake and peripheral metabolism. Physiol Behav (2011) 0.86

Role of 5-HT(2C) receptor gene variants in antipsychotic-induced weight gain. Pharmgenomics Pers Med (2011) 0.85

Update on the adverse effects of clozapine: focus on myocarditis. Curr Drug Saf (2012) 0.84

Clozapine producing weight loss: a case series with possible clinical implications - a hypothesis. J Postgrad Med (2010) 0.82

Weight gain with clozapine compared to first generation antipsychotic medications. Schizophr Bull (2004) 0.81

Clozapine-associated weight loss. J Psychopharmacol (2009) 0.81

Pharmacogenetics of leptin in antipsychotic-associated weight gain and obesity-related complications. Pharmacogenomics (2011) 0.79

Behavioral interventions for antipsychotic induced appetite changes. Curr Psychiatry Rep (2013) 0.78

Conceptualization and treatment of negative symptoms in schizophrenia. World J Psychiatry (2015) 0.78

A weight off the mind: Clozapine and profound weight loss. Aust N Z J Psychiatry (2013) 0.77

Clozapine-induced weight loss? Ann Clin Psychiatry (2011) 0.77

Recent evidence and potential mechanisms underlying weight gain and insulin resistance due to atypical antipsychotics. Rev Bras Psiquiatr (2013) 0.76

Endocannabinoid system and cardio-metabolic risk. Med J Malaysia (2008) 0.76

Dramatic weight loss associated with commencing clozapine. BMJ Case Rep (2011) 0.76