Silent Crohn's Disease Predicts Increased Bowel Damage During Multiyear Follow-up: The Consequences of Under-reporting Active Inflammation.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27753691)

Published in Inflamm Bowel Dis on November 01, 2016

Authors

Abhik Bhattacharya1, Bhavana B Rao, Ioannis E Koutroubakis, Benjamin Click, Eric J Vargas, Miguel Regueiro, Marc Schwartz, Jason M Swoger, Dmitriy Babichenko, Douglas Hartmann, Claudia R Rivers, Arthur Barrie, Jana G Hashash, Michael A Dunn, David G Binion

Author Affiliations

1: *Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; †Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; ‡Department of Gastroenterology, Heraklion University Hospital, Heraklion, Crete, Greece; §School of Information Science, University of Pittsburgh, Pittsburgh, Pennsylvania; and ‖Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Articles by these authors

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 19.08

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13

Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections. Am J Gastroenterol (2013) 7.81

Efficacy of a device to narrow the coronary sinus in refractory angina. N Engl J Med (2015) 5.36

Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study. J Pediatr (2003) 3.49

The role of trust in use of preventive services among low-income African-American women. Prev Med (2004) 2.90

Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. J Biol Chem (2002) 2.67

Vitamin D deficiency in patients with inflammatory bowel disease: association with disease activity and quality of life. JPEN J Parenter Enteral Nutr (2011) 2.49

Decision making in prostate cancer screening using decision aids vs usual care: a randomized clinical trial. JAMA Intern Med (2013) 2.38

Impact of Clostridium difficile on inflammatory bowel disease. Clin Gastroenterol Hepatol (2007) 2.20

Persistent snoring under conscious sedation during colonoscopy is a predictor of obstructive sleep apnea. Gastrointest Endosc (2010) 2.10

Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States. Ann Intern Med (2015) 2.07

Transcatheter treatment for refractory angina with the Coronary Sinus Reducer. EuroIntervention (2014) 2.07

All in the family: evaluation of the process and content of sisters' communication about BRCA1 and BRCA2 genetic test results. Am J Med Genet (2002) 2.05

Inflammatory bowel disease in the elderly is associated with worse outcomes: a national study of hospitalizations. Inflamm Bowel Dis (2009) 2.03

The bone and fat connection in inflammatory bowel diseases. Inflamm Bowel Dis (2014) 1.99

Narcotic use in patients with Crohn's disease. Am J Gastroenterol (2005) 1.83

Inflammatory bowel disease characteristics among African Americans, Hispanics, and non-Hispanic Whites: characterization of a large North American cohort. Am J Gastroenterol (2006) 1.79

Ambient air pollution correlates with hospitalizations for inflammatory bowel disease: an ecologic analysis. Inflamm Bowel Dis (2010) 1.73

Circulating levels of leptin, adiponectin, resistin, and ghrelin in inflammatory bowel disease. Inflamm Bowel Dis (2006) 1.71

Navigation skill impairment: Another dimension of the driving difficulties in minimal hepatic encephalopathy. Hepatology (2008) 1.67

Simple score to identify colectomy risk in ulcerative colitis hospitalizations. Inflamm Bowel Dis (2010) 1.67

A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis. Gastroenterology (2007) 1.64

Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. Am J Physiol Cell Physiol (2004) 1.61

Clostridium difficile and inflammatory bowel disease. Inflamm Bowel Dis (2008) 1.57

A novel risk score to stratify severity of Crohn's disease hospitalizations. Am J Gastroenterol (2010) 1.56

QuantiFERON TB gold testing for tuberculosis screening in an inflammatory bowel disease cohort in the United States. Inflamm Bowel Dis (2011) 1.55

Is endoscopy necessary for the measurement of disease activity in ulcerative colitis? Am J Gastroenterol (2005) 1.52

Stopping immunomodulators and biologics in inflammatory bowel disease patients in remission. Inflamm Bowel Dis (2011) 1.51

Food dye use in enteral feedings: a review and a call for a moratorium. Nutr Clin Pract (2002) 1.45

Does it matter where you are hospitalized for inflammatory bowel disease? A nationwide analysis of hospital volume. Am J Gastroenterol (2008) 1.44

Leflunomide treatment of Crohn's disease patients intolerant to standard immunomodulator therapy. J Clin Gastroenterol (2003) 1.44

Acquired microvascular dysfunction in inflammatory bowel disease: Loss of nitric oxide-mediated vasodilation. Gastroenterology (2003) 1.44

Temporal trends in disease outcomes related to Clostridium difficile infection in patients with inflammatory bowel disease. Inflamm Bowel Dis (2010) 1.41

A case of sigmoid endometriosis difficult to differentiate from colon cancer. BMC Gastroenterol (2003) 1.40

Pain and inflammatory bowel disease. Inflamm Bowel Dis (2009) 1.39

Cornelia de Lange syndrome in association with ulcerative colitis: a case report. J Crohns Colitis (2013) 1.39

Probiotic yogurt for the treatment of minimal hepatic encephalopathy. Am J Gastroenterol (2008) 1.36

Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol (2007) 1.29

Assessment of reliability and validity of IBD phenotyping within the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC). Inflamm Bowel Dis (2007) 1.26

Functional identity of genes detectable in expression profiling assays following globin mRNA reduction of peripheral blood samples. Clin Biochem (2007) 1.25

The vascular contribution in the pathogenesis of inflammatory bowel disease. Am J Physiol Heart Circ Physiol (2003) 1.23

CXCL12 activation of CXCR4 regulates mucosal host defense through stimulation of epithelial cell migration and promotion of intestinal barrier integrity. Am J Physiol Gastrointest Liver Physiol (2004) 1.21

Biologic therapy in the management of extraintestinal manifestations of inflammatory bowel disease. Inflamm Bowel Dis (2007) 1.20

Human intestinal microvascular endothelial cells express Toll-like receptor 5: a binding partner for bacterial flagellin. J Immunol (2004) 1.19

Impact of ulcerative colitis from patients' and physicians' perspectives: Results from the UC: NORMAL survey. Inflamm Bowel Dis (2009) 1.19

Leptin, adiponectin, resistin, and ghrelin--implications for inflammatory bowel disease. Mol Nutr Food Res (2008) 1.18

Trends in ambulatory and emergency room visits for inflammatory bowel diseases in the United States: 1994-2005. Am J Gastroenterol (2009) 1.16

Clostridium difficile enteritis: an early postoperative complication in inflammatory bowel disease patients after colectomy. J Gastrointest Surg (2007) 1.15

Late perforation by cardiac implantable electronic device leads: clinical presentation, diagnostic clues, and management. Clin Cardiol (2010) 1.14

Impact of Clostridium difficile on inflammatory bowel disease. Expert Rev Gastroenterol Hepatol (2010) 1.13

The intestinal microvasculature as a therapeutic target in inflammatory bowel disease. Ann N Y Acad Sci (2006) 1.12

Small bowel resection rates in Crohn's disease and the indication for surgery over time: experience from a large tertiary care center. Inflamm Bowel Dis (2010) 1.11

Geriatric inflammatory bowel disease: phenotypic presentation, treatment patterns, nutritional status, outcomes, and comorbidity. Dig Dis Sci (2012) 1.10

Apolipoprotein J/clusterin prevents a progressive glomerulopathy of aging. Mol Cell Biol (2002) 1.09

A randomized, controlled, double-blind trial of the adjunct use of tegaserod in whole-dose or split-dose polyethylene glycol electrolyte solution for colonoscopy preparation. Gastrointest Endosc (2008) 1.08

Con: CT colonography-not yet ready for community-wide implementation. Am J Gastroenterol (2010) 1.08

Permanent work disability in Crohn's disease. Am J Gastroenterol (2007) 1.07

Volume and yield of screening colonoscopy at a tertiary medical center after change in medicare reimbursement. Am J Gastroenterol (2003) 1.05

Subtypes of language disorders in school-age children with autism. Dev Neuropsychol (2009) 1.05

Breast and ovarian cancer screening practices in healthy women with a strong family history of breast or ovarian cancer. Breast Cancer Res Treat (2002) 1.04

Colonic tuberculosis mimicking Crohn's disease: case report. BMC Gastroenterol (2002) 1.03

Mechanisms of endotoxin tolerance in human intestinal microvascular endothelial cells. J Immunol (2003) 1.03

Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling. Proc Natl Acad Sci U S A (2013) 1.03

Mucosal angiogenesis regulation by CXCR4 and its ligand CXCL12 expressed by human intestinal microvascular endothelial cells. Am J Physiol Gastrointest Liver Physiol (2004) 1.03

Hypercoagulable states in patients with hepatocellular carcinoma. Dig Dis Sci (2004) 1.02

Relationship between proximal Crohn's disease location and disease behavior and surgery: a cross-sectional study of the IBD Genetics Consortium. Am J Gastroenterol (2012) 1.02

Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB. Am J Physiol Gastrointest Liver Physiol (2008) 1.02

Clostridium difficile and inflammatory bowel disease. Gastroenterol Clin North Am (2009) 1.02

Tiara: a novel catheter-based mitral valve bioprosthesis: initial experiments and short-term pre-clinical results. J Am Coll Cardiol (2012) 1.02

Serum hepcidin and prohepcidin concentrations in inflammatory bowel disease. Eur J Gastroenterol Hepatol (2011) 1.02

Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling. Cell Commun Signal (2004) 1.02

Longitudinal Oncology Registry of Head and Neck Carcinoma (LORHAN): analysis of chemoradiation treatment approaches in the United States. Cancer (2010) 1.00

Diagnosing anemia in inflammatory bowel disease: beyond the established markers. J Crohns Colitis (2011) 1.00

A nationwide analysis of changes in severity and outcomes of inflammatory bowel disease hospitalizations. J Gastrointest Surg (2010) 1.00

Clostridium difficile and inflammatory bowel disease. Med Clin North Am (2010) 0.99

Human esophageal microvascular endothelial cells respond to acidic pH stress by PI3K/AKT and p38 MAPK-regulated induction of Hsp70 and Hsp27. Am J Physiol Cell Physiol (2006) 0.99

Multivariate analysis suggests improved perioperative outcome in Crohn's disease patients receiving immunomodulator therapy after segmental resection and/or strictureplasty. Surgery (2003) 0.99

Long term efficacy and safety of allopurinol and azathioprine or 6-mercaptopurine in patients with inflammatory bowel disease. J Crohns Colitis (2009) 0.98

Alcohol consumption is a risk factor for colonic diverticulosis. J Clin Gastroenterol (2013) 0.98

Mucosal IgG4 cell infiltration in ulcerative colitis is linked to disease activity and primary sclerosing cholangitis. Inflamm Bowel Dis (2013) 0.97

Five-Year Period Prevalence and Characteristics of Anemia in a Large US Inflammatory Bowel Disease Cohort. J Clin Gastroenterol (2016) 0.96

Case report: magnetic resonance imaging in the diagnosis of epidural abscess complicating perirectal fistulizing Crohn's disease. Inflamm Bowel Dis (2003) 0.96

The vasculature and inflammatory bowel disease: contribution to pathogenesis and clinical pathology. Inflamm Bowel Dis (2005) 0.96

Prevention and treatment of postoperative Crohn's disease recurrence: an update for a new decade. Curr Gastroenterol Rep (2011) 0.96

The emerging role of adipocytokines as inflammatory mediators in inflammatory bowel disease. Inflamm Bowel Dis (2005) 0.95

Chronic sinonasal disease in patients with inflammatory bowel disease. Am J Rhinol (2003) 0.95

Efficacy of infliximab for extraintestinal manifestations of inflammatory bowel disease. Curr Treat Options Gastroenterol (2007) 0.92

Role of hydrogen peroxide in ACh-induced dilation of human submucosal intestinal microvessels. Am J Physiol Heart Circ Physiol (2004) 0.92