Published in J Neurooncol on October 21, 2016
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell (2010) 39.09
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol (2008) 19.86
Correlation between protein and mRNA abundance in yeast. Mol Cell Biol (1999) 16.95
The human plasma proteome: history, character, and diagnostic prospects. Mol Cell Proteomics (2002) 16.08
Membrane vesicles as conveyors of immune responses. Nat Rev Immunol (2009) 14.72
Exosomes: composition, biogenesis and function. Nat Rev Immunol (2002) 13.99
Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol (2013) 10.02
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell (2006) 8.09
Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. J Clin Oncol (2008) 6.41
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin. J Cell Biol (2005) 4.75
A comparison of selected mRNA and protein abundances in human liver. Electrophoresis (1997) 4.35
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles (2013) 4.05
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Exosome release is regulated by a calcium-dependent mechanism in K562 cells. J Biol Chem (2003) 2.71
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci U S A (2013) 2.32
New insights into the regulation and cellular functions of the ARP2/3 complex. Nat Rev Mol Cell Biol (2012) 2.25
Proteomic and immunologic analyses of brain tumor exosomes. FASEB J (2008) 2.11
Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells. Proc Natl Acad Sci U S A (2011) 2.01
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J Proteome Res (2009) 1.97
Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia. J Biol Chem (1998) 1.87
Overexpression of calreticulin increases intracellular Ca2+ storage and decreases store-operated Ca2+ influx. J Biol Chem (1996) 1.83
Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. J Extracell Vesicles (2012) 1.81
Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing. Oncotarget (2014) 1.49
Matrix-degrading proteinases are shed in membrane vesicles by ovarian cancer cells in vivo and in vitro. Clin Exp Metastasis (1999) 1.46
PTEN associates with the vault particles in HeLa cells. J Biol Chem (2002) 1.45
Vaults and the major vault protein: novel roles in signal pathway regulation and immunity. Cell Mol Life Sci (2009) 1.39
β1A integrin is a master regulator of invadosome organization and function. Mol Biol Cell (2010) 1.31
Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. RNA Biol (2013) 1.26
Exosome secretion is enhanced by invadopodia and drives invasive behavior. Cell Rep (2013) 1.26
Calreticulin in the immune system: ins and outs. Trends Immunol (2012) 1.23
Extracellular matrix protein 1 (ECM1) is over-expressed in malignant epithelial tumors. Cancer Lett (2003) 1.20
miR-1289 and "Zipcode"-like Sequence Enrich mRNAs in Microvesicles. Mol Ther Nucleic Acids (2012) 1.18
The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space. J Biol Chem (2012) 1.16
Cathepsin D is a potential serum marker for poor prognosis in glioma patients. Cancer Res (2005) 1.10
IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients. J Neuropathol Exp Neurol (2007) 1.07
Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation. EMBO Rep (2012) 1.07
Extracellular matrix 1 (ECM1) expression is a novel prognostic marker for poor long-term survival in breast cancer: a Hospital-based Cohort Study in Iowa. Ann Surg Oncol (2009) 1.05
A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Proteomics (2013) 1.04
PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling. Neuro Oncol (2010) 0.99
Glioma surgical aspirate: a viable source of tumor tissue for experimental research. Cancers (Basel) (2013) 0.99
Inhibition of glioma cell lysosome exocytosis inhibits glioma invasion. PLoS One (2012) 0.97
Calreticulin, a molecular chaperone in the endoplasmic reticulum, modulates radiosensitivity of human glioblastoma U251MG cells. Cancer Res (2006) 0.97
Integrin α5β1, the Fibronectin Receptor, as a Pertinent Therapeutic Target in Solid Tumors. Cancers (Basel) (2013) 0.95
Regulation of exosome release from mammary epithelial and breast cancer cells - a new regulatory pathway. Eur J Cancer (2014) 0.92
Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. Int J Cancer (2015) 0.91
Proteomic analysis of exosome-like vesicles derived from breast cancer cells. Anticancer Res (2012) 0.90
Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis. Oncotarget (2013) 0.90
Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes. Int J Oncol (2011) 0.88
Glioblastoma extracellular vesicles: reservoirs of potential biomarkers. Pharmgenomics Pers Med (2014) 0.88
ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion. Mol Biol Cell (2013) 0.88
Calreticulin functions as a molecular chaperone for the beta-amyloid precursor protein. Neurobiol Aging (2001) 0.87
Cause or effect of arteriogenesis: compositional alterations of microparticles from CAD patients undergoing external counterpulsation therapy. PLoS One (2012) 0.86
Downregulation of laminin alpha4 chain expression inhibits glioma invasion in vitro and in vivo. Int J Cancer (2005) 0.85
Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A. Clin Cancer Res (2014) 0.84
Correlation of ECM1 expression level with the pathogenesis and metastasis of laryngeal carcinoma. Int J Clin Exp Pathol (2013) 0.82
Upregulation of beta-amyloid precursor protein expression in glioblastoma multiforme. Neuroreport (2008) 0.82
Extracellular matrix protein 1 is correlated to carcinogenesis and lymphatic metastasis of human gastric cancer. World J Surg Oncol (2014) 0.81
LGI3 interacts with flotillin-1 to mediate APP trafficking and exosome formation. Neuroreport (2010) 0.80
The mannose 6-phosphate/insulin-like growth factor II receptor restricts the tumourigenicity and invasiveness of squamous cell carcinoma cells. Int J Cancer (2009) 0.80
Overview of Transforming Growth Factor β Superfamily Involvement in Glioblastoma Initiation and Progression. Asian Pac J Cancer Prev (2015) 0.79
Proteomic characterization of human platelet-derived microparticles. Anal Chim Acta (2013) 0.79
Membrane proteome analysis of glioblastoma cell invasion. J Neuropathol Exp Neurol (2015) 0.78
Cell migration: ESCRTing integrin degradation. Nat Rev Mol Cell Biol (2010) 0.76
Alzheimer pathology in elderly patients with glioblastoma multiforme. Arch Pathol Lab Med (2002) 0.76
MS/MS-based strategies for proteomic profiling of invasive cell structures. Proteomics (2014) 0.76
Is the mannose-6-phosphate/insulin-like growth factor 2 receptor coded by a breast cancer suppressor gene? Adv Exp Med Biol (2008) 0.76
Ultrasonic aspiration in the surgical treatment of intracranial tumors. J Neurosurg Sci (1982) 0.76