Published in Dev Dyn on November 18, 2016
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J Neurosci (2014) 5.52
G protein-coupled receptor-dependent development of human frontal cortex. Science (2004) 4.42
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination. Nat Neurosci (2013) 3.59
Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron (1994) 3.57
The extracellular matrix at a glance. J Cell Sci (2010) 3.37
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. Nature (2012) 3.09
Regulation of oligodendrocyte differentiation and myelination. Science (2010) 2.98
A G protein-coupled receptor is essential for Schwann cells to initiate myelination. Science (2009) 2.77
Motor skill learning requires active central myelination. Science (2014) 2.59
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med (2005) 2.46
CNS integrins switch growth factor signalling to promote target-dependent survival. Nat Cell Biol (2002) 2.38
Axonal prion protein is required for peripheral myelin maintenance. Nat Neurosci (2010) 2.25
Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination. Ann Neurol (2012) 2.25
Mutations in the VLGR1 gene implicate G-protein signaling in the pathogenesis of Usher syndrome type II. Am J Hum Genet (2004) 2.15
The cellular prion protein (PrP(C)): its physiological function and role in disease. Biochim Biophys Acta (2007) 2.09
GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis. Proc Natl Acad Sci U S A (2006) 2.08
Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain. Nat Neurosci (2013) 1.98
GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci (2008) 1.93
The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. Genomics (2004) 1.90
Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis. Nat Genet (2013) 1.90
Gpr126 is essential for peripheral nerve development and myelination in mammals. Development (2011) 1.77
Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants. Ann Neurol (2012) 1.71
Myelination of the nervous system: mechanisms and functions. Annu Rev Cell Dev Biol (2014) 1.69
Differentiation of axon-related Schwann cells in vitro. I. Ascorbic acid regulates basal lamina assembly and myelin formation. J Cell Biol (1987) 1.67
Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives. FEBS Lett (2003) 1.59
G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination. Proc Natl Acad Sci U S A (2011) 1.53
Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2. Proc Natl Acad Sci U S A (2010) 1.51
Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS. Mol Cell Neurosci (2004) 1.51
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling. Brain (2009) 1.49
Inhibition of Gli1 mobilizes endogenous neural stem cells for remyelination. Nature (2015) 1.49
Sticky signaling--adhesion class G protein-coupled receptors take the stage. Sci Signal (2013) 1.42
Genotype-phenotype analysis of human frontoparietal polymicrogyria syndromes. Ann Neurol (2005) 1.37
Myelin-associated glycoprotein inhibits axonal regeneration from a variety of neurons via interaction with a sialoglycoprotein. Mol Cell Neurosci (1996) 1.33
Bilateral frontoparietal polymicrogyria: clinical and radiological features in 10 families with linkage to chromosome 16. Ann Neurol (2003) 1.33
GPR56-related bilateral frontoparietal polymicrogyria: further evidence for an overlap with the cobblestone complex. Brain (2010) 1.30
There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini. Biochem Biophys Res Commun (2003) 1.30
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. Pharmacol Rev (2015) 1.29
An integrin-contactin complex regulates CNS myelination by differential Fyn phosphorylation. J Neurosci (2009) 1.27
Animal models of multiple sclerosis: the good, the bad and the bottom line. Nat Neurosci (2012) 1.25
Dynamics of oligodendrocyte generation and myelination in the human brain. Cell (2014) 1.23
Gpr126 functions in Schwann cells to control differentiation and myelination via G-protein activation. J Neurosci (2013) 1.22
Microglia enhance neurogenesis and oligodendrogenesis in the early postnatal subventricular zone. J Neurosci (2014) 1.21
A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133. Cell Rep (2014) 1.17
The translational biology of remyelination: past, present, and future. Glia (2014) 1.16
Schwann Cells: Development and Role in Nerve Repair. Cold Spring Harb Perspect Biol (2015) 1.16
Integrin-growth factor interactions as regulators of oligodendroglial development and function. Glia (2005) 1.15
The adhesion GPCR GPR126 has distinct, domain-dependent functions in Schwann cell development mediated by interaction with laminin-211. Neuron (2015) 1.13
Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126. Sci Signal (2014) 1.11
Analysis of Gpr126 function defines distinct mechanisms controlling the initiation and maturation of myelin. Development (2013) 1.11
GPR56 Regulates VEGF production and angiogenesis during melanoma progression. Cancer Res (2011) 1.11
TM7XN1, a novel human EGF-TM7-like cDNA, detected with mRNA differential display using human melanoma cell lines with different metastatic potential. FEBS Lett (1999) 1.10
Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves. J Cell Biol (2015) 1.07
Digestion products of the PH20 hyaluronidase inhibit remyelination. Ann Neurol (2013) 1.06
Disruption of the hyaluronan-based extracellular matrix in spinal cord promotes astrocyte proliferation. Glia (2005) 1.05
Impeded interaction between Schwann cells and axons in the absence of laminin alpha4. J Neurosci (2005) 1.02
Merosin and congenital muscular dystrophy. Microsc Res Tech (2000) 1.02
GPR56, a novel secretin-like human G-protein-coupled receptor gene. Genomics (1999) 1.01
A polarizing question: do M1 and M2 microglia exist? Nat Neurosci (2016) 1.00
The NC1 domain of type IV collagen promotes axonal growth in sympathetic neurons through interaction with the alpha 1 beta 1 integrin. J Cell Biol (1991) 0.99
Myelin-associated glycoprotein inhibits neurite/axon growth and causes growth cone collapse. J Neurosci Res (1996) 0.99
Hyaluronan accumulation and arrested oligodendrocyte progenitor maturation in vanishing white matter disease. Brain (2013) 0.99
Galectin-3 drives oligodendrocyte differentiation to control myelin integrity and function. Cell Death Differ (2011) 0.99
Glypican-1 and alpha4(V) collagen are required for Schwann cell myelination. J Neurosci (2006) 0.98
Merosin/laminin-2 and muscular dystrophy. Neuromuscul Disord (1996) 0.98
New insights on Schwann cell development. Glia (2015) 0.95
Mutations of GPR126 are responsible for severe arthrogryposis multiplex congenita. Am J Hum Genet (2015) 0.94
Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist. Proc Natl Acad Sci U S A (2015) 0.92
Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction. J Neurosci (2010) 0.91
Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. Eur J Neurosci (2001) 0.90
Collagen VI regulates peripheral nerve myelination and function. FASEB J (2013) 0.87
Association of GPR126 gene polymorphism with adolescent idiopathic scoliosis in Chinese populations. Genomics (2014) 0.87
Disease-associated mutations prevent GPR56-collagen III interaction. PLoS One (2012) 0.86
Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C. Proc Natl Acad Sci U S A (2013) 0.86
Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ. Exp Neurol (2013) 0.85
The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development. Nat Commun (2015) 0.85
The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6. Nature (2016) 0.84
The extracellular matrix protein laminin α2 regulates the maturation and function of the blood-brain barrier. J Neurosci (2014) 0.84
Collagen VI regulates peripheral nerve regeneration by modulating macrophage recruitment and polarization. Acta Neuropathol (2014) 0.83
The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA. Nat Commun (2015) 0.83
A novel GPR56 mutation causes bilateral frontoparietal polymicrogyria. Pediatr Neurol (2011) 0.83
Laminin-α2 Chain-Deficient Congenital Muscular Dystrophy: Pathophysiology and Development of Treatment. Curr Top Membr (2015) 0.83
Brain matrix: structure, turnover and necessity. Biochem Soc Trans (2007) 0.83
Autophagic myelin destruction by schwann cells during wallerian degeneration and segmental demyelination. Glia (2015) 0.82
The Role of Collagens in Peripheral Nerve Myelination and Function. Mol Neurobiol (2014) 0.80
Adhesion G protein-coupled receptors in nervous system development and disease. Nat Rev Neurosci (2016) 0.79
USH2 caused by GPR98 mutation diagnosed by massively parallel sequencing in advance of the occurrence of visual symptoms. Ann Otol Rhinol Laryngol (2015) 0.79
Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains. Neuron (2016) 0.78
Expression of integrins by murine MSC80 Schwann cell line: relationship to cell adhesion and migration. Neurosci Lett (1999) 0.78
Gpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice. Hum Mol Genet (2015) 0.78
Exogenous laminin induces regenerative changes in traumatized sciatic and optic nerve. Plast Reconstr Surg (1989) 0.77
Oligodendrocyte, Astrocyte, and Microglia Crosstalk in Myelin Development, Damage, and Repair. Front Cell Dev Biol (2016) 0.77
Extracellular cues influencing oligodendrocyte differentiation and (re)myelination. Exp Neurol (2016) 0.76
Laminin promotes metalloproteinase-mediated dystroglycan processing to regulate oligodendrocyte progenitor cell proliferation. J Neurochem (2015) 0.76
Cyclic AMP and Polyamines Overcome Inhibition by Myelin-Associated Glycoprotein through eIF5A-Mediated Increases in p35 Expression and Activation of Cdk5. J Neurosci (2016) 0.76
Heparin interacts with the adhesion GPCR GPR56, reduces receptor shedding, and promotes cell adhesion and motility. J Cell Sci (2016) 0.76
Effect of Laminin on Neurotrophic Factors Expression in Schwann-Like Cells Induced from Human Adipose-Derived Stem Cells In Vitro. J Mol Neurosci (2016) 0.75
Targeted exome sequencing identified two novel truncation mutations in GPR98 causing Usher syndrome. Clin Experiment Ophthalmol (2015) 0.75
Novel human pathological mutations. Gene symbol: GPR98. Disease: Usher syndrome 2C. Hum Genet (2009) 0.75
Neurologic syndrome associated with homozygous mutation at MAG sialic acid binding site. Ann Clin Transl Neurol (2016) 0.75