Expression of gp91phox and p22phox, catalytic subunits of NADPH oxidase, on microglia in Nasu-Hakola disease brains.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 27904823)

Published in Intractable Rare Dis Res on November 01, 2016

Authors

Jun-Ichi Satoh1, Yoshihiro Kino1, Motoaki Yanaizu1, Youhei Tosaki1, Kenji Sakai1, Tusyoshi Ishida2, Yuko Saito3

Author Affiliations

1: Department of Bioinformatics and Molecular Neuropathology, Meiji Pharmaceutical University, Tokyo, Japan.
2: Department of Pathology and Laboratory Medicine, Kohnodai Hospital, NCGM, Chiba, Japan.
3: Department of Laboratory Medicine, National Center Hospital, NCNP, Tokyo, Japan.

Articles cited by this

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev (2007) 21.13

NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. J Biol Chem (2003) 2.92

The genetic causes of basal ganglia calcification, dementia, and bone cysts: DAP12 and TREM2. Neurology (2005) 2.77

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury. Brain (2012) 1.82

Nox family NADPH oxidases: Molecular mechanisms of activation. Free Radic Biol Med (2014) 1.68

Microglial dysfunction in brain aging and Alzheimer's disease. Biochem Pharmacol (2014) 1.52

Nasu-Hakola disease (polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy--PLOSL): a dementia associated with bone cystic lesions. From clinical to genetic and molecular aspects. Cell Mol Neurobiol (2004) 1.44

Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury. J Neuroinflammation (2010) 1.40

ROS-dependent signal transduction. Curr Opin Cell Biol (2014) 1.37

The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease. J Neuroinflammation (2006) 1.25

Nasu-Hakola disease with a splicing mutation of TREM2 in a Japanese family. Eur J Neurol (2010) 1.17

Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation. J Cereb Blood Flow Metab (2001) 1.16

Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors. Cell Mol Life Sci (2012) 1.14

Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation. J Neuroinflammation (2012) 1.09

Immunohistochemical characterization of microglia in Nasu-Hakola disease brains. Neuropathology (2010) 0.98

Neuropathology does not Correlate with Regional Differences in the Extent of Expansion of CTG Repeats in the Brain with Myotonic Dystrophy Type 1. Acta Histochem Cytochem (2010) 0.94

Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage. J Neurochem (2015) 0.82

LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains. Orphanet J Rare Dis (2014) 0.81

Oligodendrocytes: Functioning in a Delicate Balance Between High Metabolic Requirements and Oxidative Damage. Adv Exp Med Biol (2016) 0.78