Published in Cell Commun Signal on December 01, 2016
How cells respond to interferons. Annu Rev Biochem (1998) 24.27
Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med (2001) 18.25
STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer (2009) 15.45
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med (1989) 15.15
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science (2002) 14.50
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature (1995) 11.89
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol (2007) 10.71
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol (2010) 9.59
The regulation of IL-10 production by immune cells. Nat Rev Immunol (2010) 9.18
Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J Exp Med (1993) 8.03
Interleukin-10 determines viral clearance or persistence in vivo. Nat Med (2006) 8.01
Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol (2010) 7.75
Ruminant paratuberculosis (Johne's disease): the current status and future prospects. Cornell Vet (1984) 7.21
M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol (2000) 6.61
Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol (2011) 6.34
Lysosomes: fusion and function. Nat Rev Mol Cell Biol (2007) 5.74
Mycobacteria target DC-SIGN to suppress dendritic cell function. J Exp Med (2003) 5.58
Resolution of a chronic viral infection after interleukin-10 receptor blockade. J Exp Med (2006) 4.97
The JAK-STAT signaling pathway: input and output integration. J Immunol (2007) 4.92
The immune response in tuberculosis. Annu Rev Immunol (2013) 3.91
The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells. J Exp Med (1996) 3.82
Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages. J Immunol (1994) 3.55
Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages. J Immunol (1998) 3.36
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells. J Immunol (2004) 3.13
Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosis. J Immunol (2001) 3.06
Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity. Biochem Pharmacol (2006) 3.00
Understanding latent tuberculosis: a moving target. J Immunol (2010) 2.95
The many paths to p38 mitogen-activated protein kinase activation in the immune system. Nat Rev Immunol (2006) 2.68
The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. J Interferon Cytokine Res (1999) 2.66
IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity (2006) 2.58
Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages. J Immunol (2004) 2.58
Interplay between mycobacteria and host signalling pathways. Nat Rev Microbiol (2004) 2.39
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling. Nat Immunol (2008) 2.37
NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages. J Biol Chem (2006) 2.29
T cell-derived IL-10 antagonizes macrophage function in mycobacterial infection. J Immunol (1997) 2.18
Mycobacterium avium subsp. paratuberculosis: pathogen, pathogenesis and diagnosis. Rev Sci Tech (2001) 2.16
Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol (2006) 2.11
Infection with Mycobacterium avium induces production of interleukin-10 (IL-10), and administration of anti-IL-10 antibody is associated with enhanced resistance to infection in mice. Infect Immun (1993) 2.10
The role of IL-10 in immune regulation during M. tuberculosis infection. Mucosal Immunol (2011) 2.09
Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10. J Immunol (1998) 2.05
In vivo IL-10 production reactivates chronic pulmonary tuberculosis in C57BL/6 mice. J Immunol (2002) 2.04
GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling. J Leukoc Biol (2009) 2.00
Increased antimycobacterial immunity in interleukin-10-deficient mice. Infect Immun (1999) 1.95
Preclinical and clinical manifestations of paratuberculosis (including pathology). Vet Clin North Am Food Anim Pract (1996) 1.95
STAT3 signaling: anticancer strategies and challenges. Mol Interv (2011) 1.95
A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages. J Immunol (2000) 1.90
Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation. J Immunol (2002) 1.89
Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter? Immunol Rev (2007) 1.88
The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages. J Immunol (2005) 1.88
Cutting edge: involvement of the type I IFN production and signaling pathway in lipopolysaccharide-induced IL-10 production. J Immunol (2007) 1.87
Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1. J Exp Med (2006) 1.84
Survival of Mycobacterium tuberculosis in host macrophages involves resistance to apoptosis dependent upon induction of antiapoptotic Bcl-2 family member Mcl-1. J Immunol (2003) 1.80
Immunology of tuberculosis. Indian J Med Res (2004) 1.80
Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action. J Biol Chem (1999) 1.77
MicroRNA-466l upregulates IL-10 expression in TLR-triggered macrophages by antagonizing RNA-binding protein tristetraprolin-mediated IL-10 mRNA degradation. J Immunol (2010) 1.74
Transitions in immune responses to Mycobacterium paratuberculosis. Vet Microbiol (2000) 1.72
Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets. Gut (2003) 1.67
IL-10 inhibits miR-155 induction by toll-like receptors. J Biol Chem (2010) 1.65
Protection against tuberculosis: cytokines, T cells, and macrophages. Ann Rheum Dis (2002) 1.61
The mannose receptor mediates uptake of pathogenic and nonpathogenic mycobacteria and bypasses bactericidal responses in human macrophages. Infect Immun (1999) 1.61
Impaired M. tuberculosis-mediated apoptosis in alveolar macrophages from HIV+ persons: potential role of IL-10 and BCL-3. J Leukoc Biol (2009) 1.61
Tuberculosis is associated with a down-modulatory lung immune response that impairs Th1-type immunity. J Immunol (2009) 1.60
STAT3 regulates NF-kappaB recruitment to the IL-12p40 promoter in dendritic cells. Blood (2004) 1.58
Pathological evaluation of paratuberculosis in naturally infected cattle. Vet Pathol (1978) 1.58
Potent inhibition of macrophage responses to IFN-gamma by live virulent Mycobacterium tuberculosis is independent of mature mycobacterial lipoproteins but dependent on TLR2. J Immunol (2006) 1.57
How TNF was recognized as a key mechanism of disease. Cytokine Growth Factor Rev (2007) 1.55
cAMP-induced Interleukin-10 promoter activation depends on CCAAT/enhancer-binding protein expression and monocytic differentiation. J Biol Chem (2002) 1.51
Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Crit Rev Immunol (2012) 1.49
Cytokine gene expression in peripheral blood mononuclear cells and tissues of cattle infected with Mycobacterium avium subsp. paratuberculosis: evidence for an inherent proinflammatory gene expression pattern. Infect Immun (2004) 1.45
Interleukin-10 promotes Mycobacterium tuberculosis disease progression in CBA/J mice. J Immunol (2008) 1.42
Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages. J Immunol (2003) 1.41
Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production. J Immunol (2005) 1.41
IL-10 blocks phagosome maturation in mycobacterium tuberculosis-infected human macrophages. Am J Respir Cell Mol Biol (2010) 1.40
Modulation of T cell cytokine production by miR-144* with elevated expression in patients with pulmonary tuberculosis. Mol Immunol (2011) 1.35
IL-10 induces IL-10 in primary human monocyte-derived macrophages via the transcription factor Stat3. J Immunol (2007) 1.34
Crohn's disease and the mycobacterioses: a quarter century later. Causation or simple association? Crit Rev Microbiol (2012) 1.33
MicroRNAs regulate dendritic cell differentiation and function. J Immunol (2011) 1.32
MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation. FEBS Lett (2011) 1.29
Nonopsonic and opsonic association of Mycobacterium tuberculosis with resident alveolar macrophages is inefficient. J Immunol (1998) 1.29
Induction of p38 mitogen-activated protein kinase reduces early endosome autoantigen 1 (EEA1) recruitment to phagosomal membranes. J Biol Chem (2003) 1.29
Characterization of the intracellular survival of Mycobacterium avium ssp. paratuberculosis: phagosomal pH and fusogenicity in J774 macrophages compared with other mycobacteria. Cell Microbiol (2001) 1.27
Does a Th1 over Th2 dominancy really exist in the early stages of Mycobacterium avium subspecies paratuberculosis infections? Immunobiology (2010) 1.25
Lipopolysaccharide-induced transcriptional activation of interleukin-10 is mediated by MAPK- and NF-kappaB-induced CCAAT/enhancer-binding protein delta in mouse macrophages. Cell Signal (2006) 1.24
IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes. Proc Natl Acad Sci U S A (2012) 1.24
Epidemiology and economics of paratuberculosis. Vet Clin North Am Food Anim Pract (2011) 1.19
Increased resistance to mycobacterial infection in the absence of interleukin-10. Immunology (2000) 1.18
Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens. Infect Immun (2011) 1.16
Disruption of STAT3 by niclosamide reverses radioresistance of human lung cancer. Mol Cancer Ther (2013) 1.15
Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity. J Immunol (2001) 1.15
Host responses to Mycobacterium avium subsp. paratuberculosis: a complex arsenal. Anim Health Res Rev (2007) 1.14
Inhibition of p38 MAP kinase activity enhances axonal regeneration. Exp Neurol (2003) 1.13
IL-10 underlies distinct susceptibility of BALB/c and C57BL/6 mice to Mycobacterium avium infection and influences efficacy of antibiotic therapy. J Immunol (2007) 1.13
STAT signaling is active during early mammalian development. Dev Dyn (1997) 1.12
Cytokine responses of bovine macrophages to diverse clinical Mycobacterium avium subspecies paratuberculosis strains. BMC Microbiol (2006) 1.11
Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia. PLoS One (2013) 1.09
Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma. J Immunol (2001) 1.07