Erythropoiesis-stimulating agents significantly delay the onset of a regular transfusion need in nontransfused patients with lower-risk myelodysplastic syndrome.

PubWeight™: 0.78‹?›

🔗 View Article (PMID 27926979)

Published in J Intern Med on December 07, 2016

Authors

H K G Garelius1, W T Johnston2, A G Smith2, S Park3, L de Swart4, P Fenaux5, A Symeonidis6, G Sanz7, J Čermák8, R Stauder9, L Malcovati10, M Mittelman11, A A van de Loosdrecht12, C J van Marrewijk4, D Bowen13, S Crouch2, T J M de Witte14, E Hellström-Lindberg15

Author Affiliations

1: Department of Medicine, Section of Hematology and Coagulation, Sahlgrenska University Hospital, Gothenburg, Sweden.
2: Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK.
3: Clinique Universitaire d'hématologie, CHU de Grenoble, Université Grenoble, Grenoble, France.
4: Department of Hematology, Radboud university medical center, Nijmegen, the Netherlands.
5: Service d'Hématologie, Hôpital Saint-Louis, Assistance Publique des Hôpitaux de Paris (AP-HP) and Université Paris 7, Paris, France.
6: Department of Medicine, Division of Hematology, University of Patras Medical School, Patras, Greece.
7: Department of Hematology, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
8: Department of Clinical Hematology, Institute of Hematology & Blood Transfusion, Praha, Czech Republic.
9: Department of Internal Medicine V (Hematology and Oncology), Innsbruck Medical University, Innsbruck, Austria.
10: Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
11: Department of Medicine A, Tel Aviv Sourasky (Ichilov) Medical Center, Tel Aviv, Israel.
12: Department of Hematology, VU Institute of Cancer and Immunology, VU University Medical Center, Amsterdam, the Netherlands.
13: St. James's Institute of Oncology, Leeds Teaching Hospitals, Leeds, UK.
14: Department of Tumor Immunology, Nijmegen Center for Molecular Life Sciences, Radboud university medical center, Nijmegen, the Netherlands.
15: Department of Medicine, Division of Hematology, Karolinska Institutet, Stockholm, Sweden.

Articles cited by this

Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood (2006) 8.33

A note on quantifying follow-up in studies of failure time. Control Clin Trials (1996) 7.96

Adjusted survival curves with inverse probability weights. Comput Methods Programs Biomed (2004) 5.11

Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet. Blood (2013) 2.97

The use of propensity score methods with survival or time-to-event outcomes: reporting measures of effect similar to those used in randomized experiments. Stat Med (2013) 2.32

Treatment of myelodysplastic syndrome patients with erythropoietin with or without granulocyte colony-stimulating factor: results of a prospective randomized phase 3 trial by the Eastern Cooperative Oncology Group (E1996). Blood (2009) 1.94

Erythropoietin and granulocyte-colony stimulating factor treatment associated with improved survival in myelodysplastic syndrome. J Clin Oncol (2008) 1.90

A validated decision model for treating the anaemia of myelodysplastic syndromes with erythropoietin + granulocyte colony-stimulating factor: significant effects on quality of life. Br J Haematol (2003) 1.81

Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF: the GFM experience. Blood (2007) 1.67

Darbepoetin alfa for the treatment of anemia associated with myelodysplastic syndromes: efficacy and quality of life. Leuk Lymphoma (2010) 1.61

Early introduction of ESA in low risk MDS patients may delay the need for RBC transfusion: a retrospective analysis on 112 patients. Leuk Res (2010) 1.47

Long-term outcome of treatment of anemia in MDS with erythropoietin and G-CSF. Blood (2005) 1.30

No increase in age-specific incidence of myelodysplastic syndromes. Haematologica (2004) 1.27

Treatment of anemia in myelodysplastic syndromes with granulocyte colony-stimulating factor plus erythropoietin: results from a randomized phase II study and long-term follow-up of 71 patients. Blood (1998) 1.19

Myelodysplastic syndromes: clinical practice guidelines in oncology. J Natl Compr Canc Netw (2013) 1.12

Guidelines for the diagnosis and management of adult myelodysplastic syndromes. Br J Haematol (2013) 0.99

Economic impact on US Medicare of a new diagnosis of myelodysplastic syndromes and the incremental costs associated with blood transfusion need. Transfusion (2012) 0.94

Myelodysplastic syndromes, version 2.2015. J Natl Compr Canc Netw (2015) 0.92

Quality of life, physical function and MRI T2* in elderly low-risk MDS patients treated to a haemoglobin level of ≥120 g/L with darbepoetin alfa ± filgrastim or erythrocyte transfusions. Eur J Haematol (2011) 0.89

Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry. Br J Haematol (2015) 0.88

High response rate and improved exercise capacity and quality of life with a new regimen of darbepoetin alfa with or without filgrastim in lower-risk myelodysplastic syndromes: a phase II study by the GFM. Ann Hematol (2013) 0.82

Weekly standard doses of rh-EPO are highly effective for the treatment of anemic patients with low-intermediate 1 risk myelodysplastic syndromes. Leuk Res (2011) 0.79

Validation of the new comprehensive cytogenetic scoring system (NCCSS) on 630 consecutive de novo MDS patients from a single institution. Am J Hematol (2013) 0.79