Published in J Virol on December 07, 2016
Endoplasmic reticulum-mediated unfolded protein response and mitochondrial apoptosis in cancer. Biochim Biophys Acta (2016) 0.75
Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication. Viruses (2017) 0.75
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell (2001) 18.68
The mammalian unfolded protein response. Annu Rev Biochem (2005) 16.31
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol (2003) 11.17
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell (2000) 9.13
Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep (2006) 8.16
Orchestrating the unfolded protein response in health and disease. J Clin Invest (2002) 7.60
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity (2004) 6.72
Transcriptional and translational control in the Mammalian unfolded protein response. Annu Rev Cell Dev Biol (2002) 6.48
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell (1997) 6.26
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol (2009) 4.51
Endoplasmic reticulum stress responses. Cell Mol Life Sci (2008) 3.11
Signaling the unfolded protein response from the endoplasmic reticulum. J Biol Chem (2004) 2.87
Viruses, endoplasmic reticulum stress, and interferon responses. Cell Death Differ (2006) 2.72
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol (2003) 2.70
Degradation of cellular mRNAs induced by a virion-associated factor during herpes simplex virus infection of Vero cells. J Virol (1985) 2.57
The unfolded protein response: integrating stress signals through the stress sensor IRE1α. Physiol Rev (2011) 2.50
Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome. Mol Cell (2009) 2.47
Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response. J Biol Chem (2004) 2.29
Viral control of mitochondrial apoptosis. PLoS Pathog (2008) 2.21
ER chaperone functions during normal and stress conditions. J Chem Neuroanat (2004) 2.13
Flavivirus infection activates the XBP1 pathway of the unfolded protein response to cope with endoplasmic reticulum stress. J Virol (2006) 2.02
PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway. Mol Biol Cell (2005) 1.88
mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease. J Virol (2002) 1.87
mRNA decay during herpesvirus infections: interaction between a putative viral nuclease and a cellular translation factor. J Virol (2001) 1.77
ER stress and its regulator X-box-binding protein-1 enhance polyIC-induced innate immune response in dendritic cells. Eur J Immunol (2011) 1.66
The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific. Proc Natl Acad Sci U S A (2004) 1.62
Hepatitis C virus envelope proteins regulate CHOP via induction of the unfolded protein response. FASEB J (2005) 1.61
Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2. Mol Cell Biol (1996) 1.42
Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein. J Virol (2005) 1.38
The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs. Proc Natl Acad Sci U S A (2004) 1.32
The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A. J Virol (2006) 1.31
Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3. J Virol (2011) 1.24
Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5. J Virol (2012) 1.14
The virion host shutoff endonuclease (UL41) of herpes simplex virus interacts with the cellular cap-binding complex eIF4F. J Virol (2010) 1.07
Herpes simplex virus 1 counteracts tetherin restriction via its virion host shutoff activity. J Virol (2013) 1.01
Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway. J Biol Chem (2011) 1.01
Herpes simplex virus 1 E3 ubiquitin ligase ICP0 protein inhibits tumor necrosis factor alpha-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1. J Virol (2013) 0.97
Comprehensive characterization of interaction complexes of herpes simplex virus type 1 ICP22, UL3, UL4, and UL20.5. J Virol (2010) 0.97
How viruses use the endoplasmic reticulum for entry, replication, and assembly. Cold Spring Harb Perspect Biol (2013) 0.93
Molecular anatomy of subcellular localization of HSV-1 tegument protein US11 in living cells. Virus Res (2010) 0.92
Virus-encoded endonucleases: expected and novel functions. Wiley Interdiscip Rev RNA (2013) 0.91
Herpes simplex virus-1 disarms the unfolded protein response in the early stages of infection. Cell Stress Chaperones (2012) 0.91
Herpes simplex virus 1 counteracts viperin via its virion host shutoff protein UL41. J Virol (2014) 0.89
Herpes simplex virus 1 UL41 protein abrogates the antiviral activity of hZAP by degrading its mRNA. Virol J (2015) 0.85
Innate immunity at mucosal surfaces: the IRE1-RIDD-RIG-I pathway. Trends Immunol (2015) 0.82
Herpes Simplex Virus 1 (HSV-1) and HSV-2 Mediate Species-Specific Modulations of Programmed Necrosis through the Viral Ribonucleotide Reductase Large Subunit R1. J Virol (2015) 0.76
Herpes Simplex Virus Type 1 Ubiquitin-specific Protease UL36 abrogates NF-κB Activation in DNA Sensing Signal Pathway. J Virol (2016) 0.76
Herpes Simplex Virus 1 Abrogates cGAS/STING-Mediated Cytosolic DNA-sensing Pathway via Its Virion Host Shutoff Protein UL41. J Virol (2017) 0.75
Herpes Simplex Virus Type 1 UL24 Abrogates DNA Sensing Signal Pathway by inhibiting NF-κB Activation. J Virol (2017) 0.75