Published in Oncotarget on December 20, 2016
Intratumor and Intertumor Heterogeneity in Melanoma. Transl Oncol (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
Cancer statistics, 2013. CA Cancer J Clin (2013) 84.72
Mutations of the BRAF gene in human cancer. Nature (2002) 65.42
Global cancer statistics, 2012. CA Cancer J Clin (2015) 53.52
Cancer genome landscapes. Science (2013) 25.33
MethPrimer: designing primers for methylation PCRs. Bioinformatics (2002) 14.48
A decade of exploring the cancer epigenome - biological and translational implications. Nat Rev Cancer (2011) 11.33
Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications. Bioinformatics (2011) 9.79
Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature (1983) 9.28
Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. Proc Natl Acad Sci U S A (2005) 8.10
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol (2009) 7.59
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles. Genome Biol (2012) 3.44
Genomics: ENCODE explained. Nature (2012) 2.62
Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell (2014) 2.28
Genome-wide screen of promoter methylation identifies novel markers in melanoma. Genome Res (2009) 2.13
Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis. Hum Mol Genet (2013) 1.95
Metastatic cancer cell. Annu Rev Pathol (2008) 1.85
Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition. J Biol Chem (2011) 1.70
Identification of Arx transcriptional targets in the developing basal forebrain. Hum Mol Genet (2008) 1.58
Comparison of alignment software for genome-wide bisulphite sequence data. Nucleic Acids Res (2012) 1.45
Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma. Cancer Res (2008) 1.43
EpiExplorer: live exploration and global analysis of large epigenomic datasets. Genome Biol (2012) 1.40
Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. PLoS Genet (2012) 1.35
A gene expression signature of invasive potential in metastatic melanoma cells. PLoS One (2009) 1.21
Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies. J Transl Med (2010) 1.17
DMAP: differential methylation analysis package for RRBS and WGBS data. Bioinformatics (2014) 1.12
DNA-methylation profiling distinguishes malignant melanomas from benign nevi. Pigment Cell Melanoma Res (2011) 1.08
Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity. Dev Biol (2009) 1.06
Emerging roles of the EBF family of transcription factors in tumor suppression. Mol Cancer Res (2009) 1.06
Technical considerations for reduced representation bisulfite sequencing with multiplexed libraries. J Biomed Biotechnol (2012) 1.04
Mapping the zebrafish brain methylome using reduced representation bisulfite sequencing. Epigenetics (2013) 1.02
Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR. Nat Med (2015) 0.98
PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression. Melanoma Res (2011) 0.97
Targeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naïve patient melanomas. Clin Epigenetics (2015) 0.93
Gene signatures associated with mouse postnatal hindbrain neural stem cells and medulloblastoma cancer stem cells identify novel molecular mediators and predict human medulloblastoma molecular classification. Cancer Discov (2012) 0.89
Aberrant DNA methylation and tumor suppressive activity of the EBF3 gene in gastric carcinoma. Int J Cancer (2011) 0.85
Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma. Genome Biol (2015) 0.85
Base-resolution DNA methylation landscape of zebrafish brain and liver. Genom Data (2014) 0.84
DNA methylation and epigenomics: new technologies and emerging concepts. Genome Biol (2015) 0.84
EBF factors drive expression of multiple classes of target genes governing neuronal development. Neural Dev (2011) 0.84
Genome-wide DNA methylation map of human neutrophils reveals widespread inter-individual epigenetic variation. Sci Rep (2015) 0.84
Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma. Epigenetics (2014) 0.81
Placental Hypomethylation Is More Pronounced in Genomic Loci Devoid of Retroelements. G3 (Bethesda) (2016) 0.81
LINE-1 hypermethylation in peripheral blood of cutaneous melanoma patients is associated with metastasis. Melanoma Res (2015) 0.80
Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma. Proc Natl Acad Sci U S A (2010) 0.80
Genome-scale DNA methylome and transcriptome profiling of human neutrophils. Sci Data (2016) 0.80
Inhibition of invasion and metastasis by DMBT, a novel trehalose derivative, through Akt/GSK-3β/β-catenin pathway in B16BL6 cells. Chem Biol Interact (2014) 0.80
Constitutional promoter methylation and risk of familial melanoma. Epigenetics (2014) 0.78
Sex differences in DNA methylation and expression in zebrafish brain: a test of an extended 'male sex drive' hypothesis. Gene (2016) 0.77
PTEN Methylation Dependent Sinonasal Mucosal Melanoma. Cancer Res Treat (2015) 0.76
scan_tcga tools for integrated epigenomic and transcriptomic analysis of tumor subgroups. Epigenomics (2016) 0.76
Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia. J Exp Clin Cancer Res (2015) 0.76