Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patient-derived GBM tumor cells.

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🔗 View Article (PMID 28178667)

Published in Oncotarget on March 07, 2017

Authors

Amanda Tivnan1, Tatjana Heilinger1,2, Joanne M Ramsey3, Gemma O'Connor3, Jenny L Pokorny4,5, Jann N Sarkaria4, Brett W Stringer6, Bryan W Day6, Andrew W Boyd6, Ella L Kim7, Holger N Lode8, Sally-Ann Cryan3, Jochen H M Prehn1

Author Affiliations

1: Centre for Systems Medicine, Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, York House, Dublin 2, Ireland.
2: IMC Fachhochschule Krems, University of Applied Sciences, Krems, Austria.
3: School of Pharmacy, Royal College of Surgeons in Ireland, York House, Dublin 2, Ireland & Tissue Engineering Research Group, Department of Anatomy, RCSI and Centre for Research in Medical Devices (CURAM), NUIG, Ireland.
4: Department of Radiation Oncology, Mayo Clinic, Rochester, MN, United States of America.
5: Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA.
6: Brain Cancer Research Unit, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
7: Laboratory of Neurooncology, Department of Neurosurgery, Johannes Gutenberg University Medical Center, Mainz, Germany.
8: Department of Paediatrics and Paediatric Haematology/Oncology, University of Greifswald, Greifswald, Germany.

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