Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing data.

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🔗 View Article (PMID 28185561)

Published in BMC Bioinformatics on November 08, 2016

Authors

Ítalo Faria do Valle1,2, Enrico Giampieri1, Giorgia Simonetti3, Antonella Padella3, Marco Manfrini3, Anna Ferrari3, Cristina Papayannidis3, Isabella Zironi1, Marianna Garonzi4, Simona Bernardi5, Massimo Delledonne4,6, Giovanni Martinelli3, Daniel Remondini7, Gastone Castellani1

Author Affiliations

1: Department of Physics and Astronomy, University of Bologna, Bologna, Italy.
2: CAPES Foundation, Ministry of Education of Brazil, Brasília, DF, Brazil.
3: Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
4: Department of Biotechnology, University of Verona, Verona, Italy.
5: Unit of Blood Diseases and Stem Cell Transplantation, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
6: Personal Genomics, Verona, Italy.
7: Department of Physics and Astronomy, University of Bologna, Bologna, Italy. daniel.remondini@unibo.it.

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