Virulence studies, in mice, of transposon-induced mutants of Staphylococcus aureus differing in capsule size.

PubWeight™: 2.23‹?› | Rank: Top 2%

🔗 View Article (PMID 2821124)

Published in J Infect Dis on November 01, 1987

Authors

J C Lee1, M J Betley, C A Hopkins, N E Perez, G B Pier

Author Affiliations

1: Channing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts 02115.

Articles citing this

Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria. Microbiol Mol Biol Rev (2006) 4.88

Staphylococcus aureus virulence genes identified by bursa aurealis mutagenesis and nematode killing. Proc Natl Acad Sci U S A (2004) 3.89

Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections. Proc Natl Acad Sci U S A (2000) 3.46

Staphylococcus aureus capsular polysaccharides. Clin Microbiol Rev (2004) 3.40

Murine model of cutaneous infection with gram-positive cocci. Infect Immun (1992) 2.92

Type 1 capsule genes of Staphylococcus aureus are carried in a staphylococcal cassette chromosome genetic element. J Bacteriol (2002) 2.76

Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis. Infect Immun (2003) 2.59

Sequence analysis and molecular characterization of genes required for the biosynthesis of type 1 capsular polysaccharide in Staphylococcus aureus. J Bacteriol (1994) 2.54

Virulence of Staphylococcus aureus mutants altered in type 5 capsule production. Infect Immun (1991) 2.29

A Staphylococcus aureus capsular polysaccharide (CP) vaccine and CP-specific antibodies protect mice against bacterial challenge. Infect Immun (1996) 2.13

Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus. J Exp Med (2004) 2.12

Isolation and characterization of transposon mutants of Staphylococcus epidermidis deficient in capsular polysaccharide/adhesin and slime. Infect Immun (1993) 1.99

Effects of in vitro and in vivo growth conditions on expression of type 8 capsular polysaccharide by Staphylococcus aureus. Infect Immun (1993) 1.90

The role of staphylococcal polysaccharide microcapsule expression in septicemia and septic arthritis. Infect Immun (1997) 1.80

Synthesis and immunologic properties in mice of vaccines composed of Staphylococcus aureus type 5 and type 8 capsular polysaccharides conjugated to Pseudomonas aeruginosa exotoxin A. Infect Immun (1990) 1.69

Adherence of Staphylococcus aureus to endothelial cells: influence of capsular polysaccharide, global regulator agr, and bacterial growth phase. Infect Immun (2000) 1.68

Phagocytic killing of encapsulated and microencapsulated Staphylococcus aureus by human polymorphonuclear leukocytes. Infect Immun (1992) 1.67

Staphylococcus aureus strains that express serotype 5 or serotype 8 capsular polysaccharides differ in virulence. Infect Immun (2005) 1.62

Staphylococcus aureus capsular types and antibody response to lung infection in patients with cystic fibrosis. J Clin Microbiol (1988) 1.50

Spontaneous elaboration of transforming growth factor beta suppresses host defense against bacterial infection in autoimmune MRL/lpr mice. J Exp Med (1994) 1.43

Cloning of type 8 capsule genes and analysis of gene clusters for the production of different capsular polysaccharides in Staphylococcus aureus. J Bacteriol (1996) 1.31

Staphylococcus aureus Cap5O has UDP-ManNAc dehydrogenase activity and is essential for capsule expression. Infect Immun (2001) 1.30

Presence of a capsule in Erysipelothrix rhusiopathiae and its relationship to virulence for mice. Infect Immun (1994) 1.18

Antibodies to capsular polysaccharides are not protective against experimental Staphylococcus aureus endocarditis. Infect Immun (1995) 1.15

Staphylococcus aureus cap5P encodes a UDP-N-acetylglucosamine 2-epimerase with functional redundancy. J Bacteriol (1999) 1.13

Staphylococcus aureus exopolysaccharide in vivo demonstrated by immunomagnetic separation and electron microscopy. J Clin Microbiol (1989) 1.10

Promoter analysis of the cap8 operon, involved in type 8 capsular polysaccharide production in Staphylococcus aureus. J Bacteriol (1999) 1.08

Staphylococcus aureus capsular polysaccharide types 5 and 8 reduce killing by bovine neutrophils in vitro. Infect Immun (2005) 0.99

Animal and human antibodies to distinct Staphylococcus aureus antigens mutually neutralize opsonic killing and protection in mice. J Clin Invest (2010) 0.98

Nanoscale cell wall deformation impacts long-range bacterial adhesion forces on surfaces. Appl Environ Microbiol (2013) 0.95

Preclinical Efficacy of Clumping Factor A in Prevention of Staphylococcus aureus Infection. MBio (2016) 0.80

Avirulence and immunogenicity in mice of a bovine mastitis Staphylococcus aureus mutant. Can J Vet Res (1998) 0.80

Possible common biological and immunological properties for detecting encapsulated strains of Staphylococcus epidermidis. J Clin Microbiol (1988) 0.79

The therapeutic effect of chlorogenic acid against Staphylococcus aureus infection through sortase A inhibition. Front Microbiol (2015) 0.78

A murine model of renal abscess formation. Clin Diagn Lab Immunol (1999) 0.75

Molecular biology and respiratory disease. 6. Modern molecular biology and respiratory bacterial infections: a revolution on the horizon. Thorax (1990) 0.75

Indolent Staphylococcus aureus pneumonia. West J Med (1990) 0.75

Articles by these authors

The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage. Nature (1983) 19.44

Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist. Microbes Infect (2000) 7.50

Pseudomonas aeruginosa isolates from patients with cystic fibrosis: a class of serum-sensitive, nontypable strains deficient in lipopolysaccharide O side chains. Infect Immun (1983) 6.24

Genetics of bacterial enterotoxins. Annu Rev Microbiol (1986) 4.63

Broadly protective vaccine for Staphylococcus aureus based on an in vivo-expressed antigen. Science (1999) 4.08

Pulmonary disease associated with Pseudomonas aeruginosa in cystic fibrosis: current status of the host-bacterium interaction. J Infect Dis (1985) 3.61

The ica locus of Staphylococcus epidermidis encodes production of the capsular polysaccharide/adhesin. Infect Immun (1998) 3.44

Isolation and characterization of a capsular polysaccharide adhesin from Staphylococcus epidermidis. J Infect Dis (1988) 3.15

Glucose and nonmaintained pH decrease expression of the accessory gene regulator (agr) in Staphylococcus aureus. Infect Immun (1992) 2.70

Immunological basis of serum resistance of Neisseria gonorrhoeae. J Gen Microbiol (1982) 2.66

Immunochemical characterization of the mucoid exopolysaccharide of Pseudomonas aeruginosa. J Infect Dis (1983) 2.59

Staphylococcal enterotoxin A is encoded by phage. Science (1985) 2.57

Role of Pseudomonas aeruginosa mucoid exopolysaccharide in adherence to tracheal cells. Infect Immun (1985) 2.54

Acquisition of expression of the Pseudomonas aeruginosa ExoU cytotoxin leads to increased bacterial virulence in a murine model of acute pneumonia and systemic spread. Infect Immun (2000) 2.41

Cloning and nucleotide sequence of the type E staphylococcal enterotoxin gene. J Bacteriol (1988) 2.41

Relationship between cytotoxicity and corneal epithelial cell invasion by clinical isolates of Pseudomonas aeruginosa. Infect Immun (1996) 2.40

Induction of human interleukin-1 by toxic-shock-syndrome toxin-1. J Infect Dis (1985) 2.37

Pseudomonas aeruginosa invades corneal epithelial cells during experimental infection. Infect Immun (1994) 2.37

Pseudomonas aeruginosa invasion of and multiplication within corneal epithelial cells in vitro. Infect Immun (1995) 2.27

Steady-state staphylococcal enterotoxin type C mRNA is affected by a product of the accessory gene regulator (agr) and by glucose. Infect Immun (1991) 2.25

Identification and characterization of staphylococcal enterotoxin types G and I from Staphylococcus aureus. Infect Immun (1998) 2.22

Isolation and characterization of a high-molecular-weight polysaccharide from the slime of Pseudomonas aeruginosa. Infect Immun (1978) 2.22

Rapid and sensitive method for evaluating Pseudomonas aeruginosa virulence factors during corneal infections in mice. Infect Immun (1995) 2.17

A rabbit model of toxic shock syndrome that uses a constant, subcutaneous infusion of toxic shock syndrome toxin 1. Infect Immun (1987) 2.13

Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections. Infect Immun (1997) 2.11

Protective immunity induced in mice by immunization with high-molecular-weight polysaccharide from Pseudomonas aeruginosa. Infect Immun (1978) 2.04

Pathogenesis of infections related to intravascular catheterization. Clin Microbiol Rev (1993) 2.02

Isolation and characterization of transposon mutants of Staphylococcus epidermidis deficient in capsular polysaccharide/adhesin and slime. Infect Immun (1993) 1.99

Safety and immunogenicity of high molecular weight polysaccharide vaccine from immunotype 1 Pseudomonas aeruginosa. J Clin Invest (1982) 1.97

Pseudomonas aeruginosa adhesins for tracheobronchial mucin. Infect Immun (1987) 1.87

Lipopolysaccharide and high-molecular-weight polysaccharide serotypes of Pseudomonas aeruginosa. J Infect Dis (1982) 1.86

Staphylococcal enterotoxin A gene is associated with a variable genetic element. Proc Natl Acad Sci U S A (1984) 1.79

Polysaccharide surface antigens expressed by nonmucoid isolates of Pseudomonas aeruginosa from cystic fibrosis patients. J Clin Microbiol (1986) 1.76

Exploitation of syndecan-1 shedding by Pseudomonas aeruginosa enhances virulence. Nature (2001) 1.66

Alkaline pH decreases expression of the accessory gene regulator (agr) in Staphylococcus aureus. J Bacteriol (1992) 1.64

Extended contact lens wear enhances Pseudomonas aeruginosa adherence to human corneal epithelium. Invest Ophthalmol Vis Sci (1992) 1.60

Opsonophagocytic killing antibody to Pseudomonas aeruginosa mucoid exopolysaccharide in older noncolonized patients with cystic fibrosis. N Engl J Med (1987) 1.59

Transposon mutants of Staphylococcus epidermidis deficient in elaboration of capsular polysaccharide/adhesin and slime are avirulent in a rabbit model of endocarditis. J Infect Dis (1994) 1.59

Isolation and chemical characterization of a capsular polysaccharide antigen shared by clinical isolates of Enterococcus faecalis and vancomycin-resistant Enterococcus faecium. Infect Immun (1999) 1.57

Pulmonary outcome in cystic fibrosis is influenced primarily by mucoid Pseudomonas aeruginosa infection and immune status and only modestly by genotype. Infect Immun (1999) 1.54

Modulation of Pseudomonas aeruginosa adherence to the corneal surface by mucus. Infect Immun (1994) 1.52

Induction of interleukin-1 by strains of Staphylococcus aureus from patients with nonmenstrual toxic shock syndrome. J Infect Dis (1986) 1.52

Synthesis of lipopolysaccharide O side chains by Pseudomonas aeruginosa PAO1 requires the enzyme phosphomannomutase. J Bacteriol (1993) 1.50

Opsonophagocytic killing activity of rabbit antibody to Pseudomonas aeruginosa mucoid exopolysaccharide. Infect Immun (1985) 1.48

Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins. Infect Immun (1993) 1.47

High-molecular-weight polysaccharide antigen from Pseudomonas aeruginosa immunotype 2. Infect Immun (1981) 1.47

Nucleotide sequence of the type C3 staphylococcal enterotoxin gene suggests that intergenic recombination causes antigenic variation. J Bacteriol (1989) 1.46

Correlation of the biologic responses of C3H/HEJ mice to endotoxin with the chemical and structural properties of the lipopolysaccharides from Pseudomonas aeruginosa and Escherichia coli. J Immunol (1981) 1.44

Cloning and surface expression of Pseudomonas aeruginosa O antigen in Escherichia coli. Proc Natl Acad Sci U S A (1992) 1.43

Transgenic cystic fibrosis mice exhibit reduced early clearance of Pseudomonas aeruginosa from the respiratory tract. J Immunol (2001) 1.43

Competitive, enzyme-linked immunosorbent assay for toxic shock syndrome toxin 1. J Clin Microbiol (1985) 1.41

Antibody to the capsular polysaccharide/adhesin protects rabbits against catheter-related bacteremia due to coagulase-negative staphylococci. J Infect Dis (1990) 1.41

Endemic nosocomial transmission of Staphylococcus epidermidis bacteremia isolates in a neonatal intensive care unit over 10 years. J Infect Dis (1994) 1.38

Mucoid Escherichia coli in cystic fibrosis. N Engl J Med (1981) 1.37

Occurrence of capsular polysaccharide/adhesin among clinical isolates of coagulase-negative staphylococci. J Infect Dis (1993) 1.37

Polyclonal and monoclonal antibody therapy for experimental Pseudomonas aeruginosa pneumonia. Infect Immun (1986) 1.37

Safety and immunogenicity of group Y and group W135 meningococcal capsular polysaccharide vaccines in adults. Infect Immun (1981) 1.37

Protection against endocarditis due to Staphylococcus epidermidis by immunization with capsular polysaccharide/adhesin. Circulation (1991) 1.36

Lipopolysaccharide outer core is a ligand for corneal cell binding and ingestion of Pseudomonas aeruginosa. Invest Ophthalmol Vis Sci (1996) 1.36

Cystic fibrosis transmembrane conductance regulator-mediated corneal epithelial cell ingestion of Pseudomonas aeruginosa is a key component in the pathogenesis of experimental murine keratitis. Infect Immun (1999) 1.36

Mucoid Pseudomonas aeruginosa growing in a biofilm in vitro are killed by opsonic antibodies to the mucoid exopolysaccharide capsule but not by antibodies produced during chronic lung infection in cystic fibrosis patients. J Immunol (1995) 1.35

Cross-protection by Pseudomonas aeruginosa polysaccharides. Infect Immun (1982) 1.34

Characterization of the serogroup O11 O-antigen locus of Pseudomonas aeruginosa PA103. J Bacteriol (1999) 1.33

Prophylactic and therapeutic efficacy of antibodies to a capsular polysaccharide shared among vancomycin-sensitive and -resistant enterococci. Infect Immun (2000) 1.29

Characterization of the human immune response to a polysaccharide vaccine from Pseudomonas aeruginosa. J Infect Dis (1983) 1.25

Staphylococcal enterotoxin A gene (sea) expression is not affected by the accessory gene regulator (agr). Infect Immun (1993) 1.23

Functionally active monoclonal antibody that recognizes an epitope on the O side chain of Pseudomonas aeruginosa immunotype-1 lipopolysaccharide. Infect Immun (1986) 1.23

The carboxyl-terminal region of staphylococcal enterotoxin type A is required for a fully active molecule. Infect Immun (1991) 1.22

Chemical characterization and immunogenicity of capsular polysaccharide isolated from mucoid Staphylococcus aureus. Infect Immun (1987) 1.22

In vitro transcription of pathogenesis-related genes by purified RNA polymerase from Staphylococcus aureus. J Bacteriol (1995) 1.18

Structure of an extracellular cross-reactive polysaccharide from Pseudomonas aeruginosa immunotype 4. J Biol Chem (1988) 1.16

Induction in mice of cell-mediated immunity to Pseudomonas aeruginosa by high molecular weight polysaccharide and vinblastine. J Immunol (1982) 1.16

The rfb locus from Pseudomonas aeruginosa strain PA103 promotes the expression of O antigen by both LPS-rough and LPS-smooth isolates from cystic fibrosis patients. Mol Microbiol (1994) 1.13

Blood proteins do not promote adherence of coagulase-negative staphylococci to biomaterials. Infect Immun (1991) 1.12

Syndecan-1 shedding is enhanced by LasA, a secreted virulence factor of Pseudomonas aeruginosa. J Biol Chem (2000) 1.12

Suppression of lymphocyte and neutrophil functions by Pseudomonas aeruginosa mucoid exopolysaccharide (alginate): reversal by physicochemical, alginase, and specific monoclonal antibody treatments. Infect Immun (1993) 1.11

Phage-associated differences in staphylococcal enterotoxin A gene (sea) expression correlate with sea allele class. Infect Immun (1994) 1.10

Toxoid of Pseudomonas aeruginosa exotoxin A generated by deletion of an active-site residue. Infect Immun (1988) 1.10

Mediation of the killing of rough, mucoid isolates of Pseudomonas aeruginosa from patients with cystic fibrosis by the alternative pathway of complement. J Infect Dis (1984) 1.09

In vitro T cell-mediated killing of Pseudomonas aeruginosa. I. Evidence that a lymphokine mediates killing. J Immunol (1984) 1.09

Purified capsular polysaccharide-induced immunity to Staphylococcus aureus infection. J Infect Dis (1988) 1.09

The pathogenic role of Staphylococcus epidermidis capsular polysaccharide/adhesin in a low-inoculum rabbit model of prosthetic valve endocarditis. Circulation (1995) 1.08

The role of the CFTR in susceptibility to Pseudomonas aeruginosa infections in cystic fibrosis. Trends Microbiol (2000) 1.08

An immunohistological evaluation of Pseudomonas aeruginosa pulmonary infection in two patients with cystic fibrosis. Pediatr Res (1987) 1.07

Immunogenic and antigenic properties of a heptavalent high-molecular-weight O-polysaccharide vaccine derived from Pseudomonas aeruginosa. Infect Immun (1994) 1.06

High sodium chloride concentrations inhibit staphylococcal enterotoxin C gene (sec) expression at the level of sec mRNA. Infect Immun (1993) 1.05

In vitro T cell-mediated killing of Pseudomonas aeruginosa. II. The role of macrophages and T cell subsets in T cell killing. J Immunol (1985) 1.05

Pseudomonas aeruginosa lipopolysaccharide: evidence that the O side chains and common antigens are on the same molecule. J Bacteriol (1993) 1.05

Vaccine potential of poly-1-6 beta-D-N-succinylglucosamine, an immunoprotective surface polysaccharide of Staphylococcus aureus and Staphylococcus epidermidis. J Biotechnol (2000) 1.05

The role of cytophilic IgG3 antibody in T cell-mediated resistance to infection with the extracellular bacterium, Pseudomonas aeruginosa. J Immunol (1991) 1.05

Polyclonal B cell stimulation and interleukin 1 induction by the mucoid exopolysaccharide of Pseudomonas aeruginosa associated with cystic fibrosis. J Immunol (1985) 1.03

Immunogenic properties of Pseudomonas aeruginosa mucoid exopolysaccharide. Infect Immun (1990) 1.03

Structural analysis of the lipopolysaccharide core of a rough, cystic fibrosis isolate of Pseudomonas aeruginosa. Eur J Biochem (2001) 1.02

Influence of batch or fed-batch growth on Staphylococcus epidermidis biofilm formation. Lett Appl Microbiol (2004) 1.02

Dual roles for class II major histocompatibility complex molecules in staphylococcal enterotoxin-induced cytokine production and in vivo toxicity. Infect Immun (1992) 1.01