Published in Pharmacogn Mag on February 20, 2017
Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell (2004) 4.23
Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo. Cancer Res (2008) 1.76
Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex. Biochem Biophys Res Commun (2005) 1.65
Renal cell carcinoma: new developments in molecular biology and potential for targeted therapies. Oncologist (2007) 1.34
C-myc and c-fos in human osteosarcoma: prognostic value of mRNA and protein expression. Oncology (1998) 1.33
LRIG1 and epidermal growth factor receptor in renal cell carcinoma: a quantitative RT--PCR and immunohistochemical analysis. Br J Cancer (2003) 1.24
Expression of c-Myc, c-Fos, and c-jun in hepatocellular carcinoma. Cancer (2001) 1.16
The role of the AP-1 transcription factors c-Fos, FosB, Fra-1 and Fra-2 in the invasion process of mammary carcinomas. Breast Cancer Res Treat (2004) 1.14
C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma. Br J Cancer (2008) 1.08
beta-Sitosterol activates the sphingomyelin cycle and induces apoptosis in LNCaP human prostate cancer cells. Nutr Cancer (1998) 1.04
Epidermal growth factor receptor protein expression and genomic alterations in renal cell carcinoma. Cancer (2012) 1.00
Expression of stress-response and cell proliferation genes in renal cell carcinoma induced by oxidative stress. Am J Pathol (2000) 0.99
Expression pattern of the AP-1 family in endometrial cancer: correlations with cell cycle regulators. J Cancer Res Clin Oncol (2001) 0.99
Inverse relationship of epidermal growth factor receptor and HER2/neu gene expression in human renal cell carcinoma. Cancer Res (1990) 0.98
Beta-sitosterol induces anti-proliferation and apoptosis in human leukemic U937 cells through activation of caspase-3 and induction of Bax/Bcl-2 ratio. Biol Pharm Bull (2007) 0.98
Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis. Kidney Int (2003) 0.95
The Roles of Mitogen-Activated Protein Kinase Pathways in TGF-β-Induced Epithelial-Mesenchymal Transition. J Signal Transduct (2012) 0.94
Ochratoxin A induces oxidative DNA damage in liver and kidney after oral dosing to rats. Mol Nutr Food Res (2005) 0.93
A pathogenic role for JNK signaling in experimental anti-GBM glomerulonephritis. Kidney Int (2007) 0.92
Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress. Carcinogenesis (1998) 0.91
The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells. Adv Exp Med Biol (1991) 0.91
Phytosterols and risk of lung cancer: a case-control study in Uruguay. Lung Cancer (1998) 0.91
Beta-sitosterol inhibits cell growth and induces apoptosis in SGC-7901 human stomach cancer cells. J Agric Food Chem (2009) 0.90
Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and p38 MAPK signaling pathways in human colon cancer cell. Int J Colorectal Dis (2011) 0.89
Angiogenesis in cancer: Anti-VEGF escape mechanisms. Transl Lung Cancer Res (2012) 0.87
Effect of beta-sitosterol as inhibitor of 5 alpha-reductase in hamster prostate. Proc West Pharmacol Soc (2003) 0.85
Epidermal growth factor receptor-tyrosine kinase inhibitor (gefitinib) augments pneumonitis, but attenuates lung fibrosis in response to radiation injury in rats. J Med Invest (2012) 0.85
Hyperactivated JNK is a therapeutic target in pVHL-deficient renal cell carcinoma. Cancer Res (2013) 0.85
β-Sitosterol induces G1 arrest and causes depolarization of mitochondrial membrane potential in breast carcinoma MDA-MB-231 cells. BMC Complement Altern Med (2013) 0.85
A peptide from Porphyra yezoensis stimulates the proliferation of IEC-6 cells by activating the insulin-like growth factor I receptor signaling pathway. Int J Mol Med (2014) 0.82
beta-Sitosterol inhibits growth of HT-29 human colon cancer cells by activating the sphingomyelin cycle. Anticancer Res (1998) 0.81
Amelioration of renal carcinogenesis by bee propolis: a chemo preventive approach. Toxicol Int (2013) 0.80
The Nephrologist's Tumor: Basic Biology and Management of Renal Cell Carcinoma. J Am Soc Nephrol (2016) 0.80
Nephroprotective effect of β-sitosterol on N-diethylnitrosamine initiated and ferric nitrilotriacetate promoted acute nephrotoxicity in Wistar rats. J Basic Clin Physiol Pharmacol (2016) 0.80
MAPKs' status at early stages of renal carcinogenesis and tumors induced by ferric nitrilotriacetate. Mol Cell Biochem (2015) 0.77
Crossing paths in Human Renal Cell Carcinoma (hRCC). Int J Mol Sci (2012) 0.77
Effect of zinc(II) ions on the expression of pro- and anti-apoptotic factors in high-grade prostate carcinoma cells. Oncol Rep (2012) 0.77
Telomerase reverse transcriptase promotes the proliferation of human laryngeal carcinoma cells through activation of the activator protein 1. Oncol Lett (2013) 0.76