IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting.

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Published in Nat Commun on February 24, 2017

Authors

Kazuyoshi Takeda1,2,3,4, Masafumi Nakayama5,6, Yoshihiro Hayakawa4,7, Yuko Kojima8, Hiroaki Ikeda9,10, Naoko Imai9,11, Kouetsu Ogasawara6, Ko Okumura2,3,12, David M Thomas13, Mark J Smyth4,14,15

Author Affiliations

1: Division of Cell Biology, Biomedical Research Center, Graduate School of Medicine, Juntendo University, Bunkyo-ku, Tokyo 113-8421, Japan.
2: Department of Biofunctional Micribiota, Graduate School of Medicine, Juntendo University, Bunkyo-ku, Tokyo 113-8421, Japan.
3: Department of Immunology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan.
4: Cancer Immunology Program, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, 3002 Victoria, Australia.
5: Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai 980-8578, Japan.
6: Department of Immunobiology, Institute of Development, Aging, and Cancer, Tohoku University, Sendai 980-8575, Japan.
7: Division of Pathogenic Biochemistry, Department of Bioscience, Institute of Natural Medicine, University of Toyama, Sugitani 2630, Toyama 930-0194, Japan.
8: Laboratory of Morphology and Image Analysis, Biomedical Research Center, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
9: Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.
10: Department of Oncology, Nagasaki University Graduate School of Biomedical Science, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.
11: Department of Hematology and Oncology, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, New York 10029, USA.
12: Atopy (Allergy) Research Center, Graduate School of Medicine, Juntendo University, Bunkyo-ku, Tokyo 113-8421, Japan.
13: Cancer Division, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia.
14: Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, 4006 Queensland, Australia.
15: School of Medicine, University of Queensland, Herston, 4006 Queensland, Australia.

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