Published in Cell Death Dis on March 02, 2017
Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol (2004) 101.91
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res (2002) 76.95
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science (1984) 9.64
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature (1983) 8.18
UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science (2007) 7.90
Recent advances in neuroblastoma. N Engl J Med (2010) 7.86
Identification of ALK as a major familial neuroblastoma predisposition gene. Nature (2008) 7.38
Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature (2008) 6.80
The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol (2008) 6.66
Identification of a human mitotic checkpoint gene: hsMAD2. Science (1996) 6.37
Analysis of gene expression in single live neurons. Proc Natl Acad Sci U S A (1992) 6.15
Oncogenic mutations of ALK kinase in neuroblastoma. Nature (2008) 5.80
Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. Dev Cell (2002) 5.52
Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. Nature (2008) 5.32
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Nature (2012) 4.53
Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family. J Biol Chem (2002) 2.82
HURP is part of a Ran-dependent complex involved in spindle formation. Curr Biol (2006) 2.74
In vitro centromere and kinetochore assembly on defined chromatin templates. Nature (2011) 2.34
HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications. Immunol Cell Biol (2011) 2.28
A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture. J Natl Cancer Inst (1976) 1.82
Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification. Clin Cancer Res (2010) 1.79
Inhibition of Rac by the GAP activity of centralspindlin is essential for cytokinesis. Science (2008) 1.74
Histone deacetylase 8 in neuroblastoma tumorigenesis. Clin Cancer Res (2009) 1.71
CENP-O class proteins form a stable complex and are required for proper kinetochore function. Mol Biol Cell (2007) 1.68
KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers. Oncogene (2005) 1.64
Evidence for the development of p53 mutations after cytotoxic therapy in a neuroblastoma cell line. Cancer Res (2001) 1.52
Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma. Clin Cancer Res (2013) 1.51
High-throughput detection and multiplex identification of cell contaminations. Nucleic Acids Res (2009) 1.49
Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification. Proc Natl Acad Sci U S A (2012) 1.46
High-throughput SNP-based authentication of human cell lines. Int J Cancer (2012) 1.46
CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer. Cell (2014) 1.45
Prognostic impact of gene expression-based classification for neuroblastoma. J Clin Oncol (2010) 1.43
Drugging MYCN through an allosteric transition in Aurora kinase A. Cancer Cell (2014) 1.33
Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Nature (2015) 1.32
HTSanalyzeR: an R/Bioconductor package for integrated network analysis of high-throughput screens. Bioinformatics (2011) 1.29
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis. Proc Natl Acad Sci U S A (2007) 1.26
Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma. Clin Cancer Res (2011) 1.15
Chromosome instability accounts for reverse metastatic outcomes of pediatric and adult synovial sarcomas. J Clin Oncol (2013) 1.14
Consensus transcriptome signature of perineural invasion in pancreatic carcinoma. Mol Cancer Ther (2009) 1.09
KIF14 mRNA expression is a predictor of grade and outcome in breast cancer. Int J Cancer (2006) 1.07
TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors. Nat Genet (2015) 1.05
Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1. J Biol Chem (2009) 1.05
Histone deacetylase 10 promotes autophagy-mediated cell survival. Proc Natl Acad Sci U S A (2013) 1.01
KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression. J Cell Biol (2012) 0.99
Targeting histone deacetylases in neuroblastoma. Curr Pharm Des (2009) 0.98
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma. Nucleic Acids Res (2013) 0.98
Histone deacetylase 5 blocks neuroblastoma cell differentiation by interacting with N-Myc. Oncogene (2013) 0.95
Metal-proteinase ADAM12, kinesin 14 and checkpoint suppressor 1 as new molecular markers of laryngeal carcinoma. Eur Arch Otorhinolaryngol (2009) 0.93
HDAC11 is a novel drug target in carcinomas. Int J Cancer (2012) 0.93
Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition. Clin Cancer Res (2015) 0.93
Serial transcriptome analysis and cross-species integration identifies centromere-associated protein E as a novel neuroblastoma target. Cancer Res (2010) 0.93
p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes. PLoS One (2013) 0.92
KIF14 promotes AKT phosphorylation and contributes to chemoresistance in triple-negative breast cancer. Neoplasia (2014) 0.92
Prognostic significance of RACGAP1 mRNA expression in high-risk early breast cancer: a study in primary tumors of breast cancer patients participating in a randomized Hellenic Cooperative Oncology Group trial. Cancer Chemother Pharmacol (2012) 0.89
Kinesin family member 14 is a candidate prognostic marker for outcome of glioma patients. Cancer Epidemiol (2012) 0.88
Three genetic developmental stages of papillary renal cell tumors: duplication of chromosome 1q marks fatal progression. Int J Cancer (2009) 0.87
GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3. Cancer Res (2014) 0.87
Cyclin E1 is a common target of BMI1 and MYCN and a prognostic marker for neuroblastoma progression. Oncogene (2011) 0.85
CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres. Nat Struct Mol Biol (2016) 0.84
The MDM2 small-molecule inhibitor RG7388 leads to potent tumor inhibition in p53 wild-type neuroblastoma. Cell Death Discov (2015) 0.84
Analysis of 20 genes at chromosome band 12q13: RACGAP1 and MCRS1 overexpression in nonsmall-cell lung cancer. Genes Chromosomes Cancer (2012) 0.84
Suppression of KIF14 expression inhibits hepatocellular carcinoma progression and predicts favorable outcome. Cancer Sci (2013) 0.83
Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation. Cell Death Dis (2015) 0.83
Epigenetic therapy for solid tumors: from bench science to clinical trials. Epigenomics (2015) 0.82
Expression of RACGAP1 in high grade meningiomas: a potential role in cancer progression. J Neurooncol (2013) 0.81
APC(CDH1) targets MgcRacGAP for destruction in the late M phase. PLoS One (2013) 0.80
KIF14 and E2F3 mRNA expression in human retinoblastoma and its phenotype association. Mol Vis (2009) 0.80
Critical role of mitochondria-mediated apoptosis for JNJ-26481585-induced antitumor activity in rhabdomyosarcoma. Oncogene (2015) 0.80
The role of KIF14 in patient-derived primary cultures of high-grade serous ovarian cancer cells. J Ovarian Res (2014) 0.79
Regulation of MMP13 by antitumor microRNA-375 markedly inhibits cancer cell migration and invasion in esophageal squamous cell carcinoma. Int J Oncol (2016) 0.78
The motor protein KIF14 inhibits tumor growth and cancer metastasis in lung adenocarcinoma. PLoS One (2013) 0.78
Inhibition of KIF14 Suppresses Tumor Cell Growth and Promotes Apoptosis in Human Glioblastoma. Cell Physiol Biochem (2015) 0.78
SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores. Nat Commun (2016) 0.77
XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE. Cell Death Dis (2016) 0.76
Kif14 overexpression accelerates murine retinoblastoma development. Int J Cancer (2016) 0.76
Binimetinib inhibits MEK and is effective against neuroblastoma tumor cells with low NF1 expression. BMC Cancer (2016) 0.76
Chromosome biology: controlling CENPA mislocalization. Nat Rev Mol Cell Biol (2014) 0.76
Up-regulation of KIF14 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in cervical cancer. Biosci Rep (2016) 0.76
Genetic and functional analyses do not explain the association of high PRC1 expression with poor survival of breast carcinoma patients. Biomed Pharmacother (2016) 0.76
Structure of kif14: an engaging molecular motor. J Mol Biol (2014) 0.75
MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma. Oncotarget (2016) 0.75