Activation of E-prostanoid 3 receptor in macrophages facilitates cardiac healing after myocardial infarction.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28256515)

Published in Nat Commun on March 03, 2017

Authors

Juan Tang1,2, Yujun Shen2, Guilin Chen2, Qiangyou Wan1, Kai Wang1, Jian Zhang1,2, Jing Qin3,4, Guizhu Liu1, Shengkai Zuo1, Bo Tao1, Yu Yu1, Junwen Wang3,5,6, Michael Lazarus7, Ying Yu1,2

Author Affiliations

1: Key Laboratory of Food Safety Research, CAS Center for Excellence in Molecular Cell Science, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
2: Department of Pharmacology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China.
3: Center for Genomic Sciences, LKS Faculty of Medicine, The University of Hong Kong, 5 Sassoon Road, Hong Kong, SAR 999077, China.
4: School of Life Science, Chinese University of Hong Kong, Hong Kong, SAR 999077, China.
5: Division of Biomedical Statistics and Informatics, Center for Individualized Medicine, Mayo Clinic, Scottsdale, Arizona 85259, USA.
6: Department of Biomedical Informatics, Arizona State University, Scottsdale, Arizona 85259, USA.
7: International Institute for Integrative Sleep Medicine, University of Tsukuba, Tsukuba City, Ibaraki 305-8575, Japan.

Articles cited by this

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med (2007) 11.51

Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol (2004) 8.65

Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity (2012) 6.18

Prostaglandins and inflammation. Arterioscler Thromb Vasc Biol (2011) 4.67

Prostanoid receptors: subtypes and signaling. Annu Rev Pharmacol Toxicol (2001) 4.40

Regulation of immune responses by prostaglandin E2. J Immunol (2012) 3.93

Comparison of gene expression profiles between human and mouse monocyte subsets. Blood (2009) 3.15

Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis. J Am Coll Cardiol (2010) 2.90

Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am J Pathol (2007) 2.84

CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood (2008) 2.52

Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci U S A (2000) 2.25

Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy. Circulation (2007) 2.14

EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses. Nat Neurosci (2007) 2.05

Autocrine deactivation of macrophages in transgenic mice constitutively overexpressing IL-10 under control of the human CD68 promoter. J Immunol (2002) 2.03

M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells. J Immunol (2011) 2.02

Temporal dynamics of cardiac immune cell accumulation following acute myocardial infarction. J Mol Cell Cardiol (2013) 2.02

Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation (2006) 2.00

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival. J Clin Invest (2013) 2.00

Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation (1999) 1.93

Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function. J Immunol (2008) 1.90

Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium. Circ Res (2014) 1.78

Cyclooxygenase-2-derived prostaglandin E₂ promotes injury-induced vascular neointimal hyperplasia through the E-prostanoid 3 receptor. Circ Res (2013) 1.61

Cardiac overexpression of monocyte chemoattractant protein-1 in transgenic mice prevents cardiac dysfunction and remodeling after myocardial infarction. Circ Res (2006) 1.46

Distinct mouse coronary anatomy and myocardial infarction consequent to ligation. Coron Artery Dis (2005) 1.38

Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction. FASEB J (2012) 1.31

Mechanisms underlying TGF-beta1-induced expression of VEGF and Flk-1 in mouse macrophages and their implications for angiogenesis. J Leukoc Biol (2006) 1.28

Rac2 is critical for neutrophil primary granule exocytosis. Blood (2004) 1.26

Chemotactic action of prostaglandin E2 on mouse mast cells acting via the PGE2 receptor 3. Proc Natl Acad Sci U S A (2007) 1.16

Microsomal prostaglandin E2 synthase-1 deletion leads to adverse left ventricular remodeling after myocardial infarction. Circulation (2008) 1.14

Crosstalk between fibroblasts and inflammatory cells. Cardiovasc Res (2014) 1.13

Vascular wall-produced prostaglandin E2 exacerbates arterial thrombosis and atherothrombosis through platelet EP3 receptors. J Exp Med (2007) 1.07

Interleukin-6/soluble interleukin-6 receptor complex reduces infarct size via inhibiting myocardial apoptosis. Lab Invest (2005) 1.05

Targeted deletions of cyclooxygenase-2 and atherogenesis in mice. Circulation (2010) 1.04

Monocytes in myocardial infarction. Arterioscler Thromb Vasc Biol (2015) 1.03

Increased expression of pigment epithelium-derived factor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injury. Eur Heart J (2011) 1.00

Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors. Biochim Biophys Acta (2014) 1.00

Tissue LyC6- macrophages are generated in the absence of circulating LyC6- monocytes and Nur77 in a model of muscle regeneration. J Immunol (2013) 1.00

Control of endothelial sprouting by a Tel-CtBP complex. Nat Cell Biol (2010) 0.99

Reduction of infarct size by selective stimulation of prostaglandin EP(3)receptors in the reperfused ischemic pig heart. J Mol Cell Cardiol (2000) 0.97

Night eating and obesity in the EP3R-deficient mouse. Proc Natl Acad Sci U S A (2007) 0.94

Effects of the prostanoid EP3-receptor agonists M&B 28767 and GR 63799X on infarct size caused by regional myocardial ischaemia in the anaesthetized rat. Br J Pharmacol (1999) 0.94

Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis. Burns (2011) 0.92

Selective activation of the prostanoid EP(3) receptor reduces myocardial infarct size in rodents. Arterioscler Thromb Vasc Biol (1999) 0.92

CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization. Sci Rep (2013) 0.88

Myeloid-derived suppressor cell function is diminished in aspirin-triggered allergic airway hyperresponsiveness in mice. J Allergy Clin Immunol (2014) 0.87

Cardiospecific overexpression of the prostaglandin EP3 receptor attenuates ischemia-induced myocardial injury. Circulation (2005) 0.85

Targeting macrophage subsets for infarct repair. J Cardiovasc Pharmacol Ther (2014) 0.84

EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling. J Clin Invest (2015) 0.83

Lack of microsomal prostaglandin E(2) synthase-1 in bone marrow-derived myeloid cells impairs left ventricular function and increases mortality after acute myocardial infarction. Circulation (2012) 0.83

Cardiovascular biology of microsomal prostaglandin E synthase-1. Trends Cardiovasc Med (2010) 0.82

The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice. Endocrinology (2015) 0.81

Fibroblast growth factor-9 enhances M2 macrophage differentiation and attenuates adverse cardiac remodeling in the infarcted diabetic heart. PLoS One (2015) 0.81

Macrophage recruitment and epithelial repair following hair cell injury in the mouse utricle. Front Cell Neurosci (2015) 0.80

CX3CR1 deficiency delays acute skeletal muscle injury repair by impairing macrophage functions. FASEB J (2015) 0.78

CX3CL1-CX3CR1 Interaction Increases the Population of Ly6C(-)CX3CR1(hi) Macrophages Contributing to Unilateral Ureteral Obstruction-Induced Fibrosis. J Immunol (2015) 0.76

Prostaglandin E2 promotes hepatic bile acid synthesis by an E prostanoid receptor 3-mediated hepatocyte nuclear receptor 4α/cholesterol 7α-hydroxylase pathway in mice. Hepatology (2016) 0.76

Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum cardiomyopathy. Eur Heart J (2017) 0.76