Published in Cancer Sci on March 09, 2017
Comprehensive molecular characterization of human colon and rectal cancer. Nature (2012) 34.13
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov (2012) 26.98
Identification of c-MYC as a target of the APC pathway. Science (1998) 24.25
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal (2013) 19.54
The role of iron regulatory proteins in mammalian iron homeostasis and disease. Nat Chem Biol (2006) 5.33
Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244). Cancer Res (2010) 3.54
Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network. Annu Rev Nutr (2008) 2.98
Iron and cancer: more ore to be mined. Nat Rev Cancer (2013) 2.40
Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC. Science (1999) 2.17
Epigenetic and genetic features of 24 colon cancer cell lines. Oncogenesis (2013) 2.02
Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis. Mol Cell Biol (2006) 2.01
Ferroportin and iron regulation in breast cancer progression and prognosis. Sci Transl Med (2010) 1.94
An iron regulatory gene signature predicts outcome in breast cancer. Cancer Res (2011) 1.91
Modulation of iron transport proteins in human colorectal carcinogenesis. Gut (2006) 1.23
Hypoxia post-translationally activates iron-regulatory protein 2. J Biol Chem (1999) 1.21
A role for iron in Wnt signalling. Oncogene (2007) 1.19
Increased hepcidin expression in colorectal carcinogenesis. World J Gastroenterol (2008) 1.17
Iron chelators for the treatment of cancer. Curr Med Chem (2012) 1.16
Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers. Cancer Res (2011) 1.13
Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers. Int J Radiat Oncol Biol Phys (2006) 1.12
Tumorigenic properties of iron regulatory protein 2 (IRP2) mediated by its specific 73-amino acids insert. PLoS One (2010) 1.10
Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells. Cancer Cell (2015) 1.08
Luminal iron levels govern intestinal tumorigenesis after Apc loss in vivo. Cell Rep (2012) 1.05
Labile iron in cells and body fluids: physiology, pathology, and pharmacology. Front Pharmacol (2014) 1.03
Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib. Int J Cancer (2013) 0.97
The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway. Oncotarget (2014) 0.96
IRP2 regulates breast tumor growth. Cancer Res (2013) 0.94
Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells. Br J Cancer (2013) 0.92
Targeting cancer by binding iron: Dissecting cellular signaling pathways. Oncotarget (2015) 0.91
Oesophageal adenocarcinoma is associated with a deregulation in the MYC/MAX/MAD network. Br J Cancer (2008) 0.91
Effect of iron on the activation of the MAPK/ERK pathway in PC12 neuroblastoma cells. Biol Res (2006) 0.89
BRAF V600E mutation in colorectal cancer is associated with right-sided tumours and iron deficiency anaemia. Anticancer Res (2015) 0.81
Alginate-Iron Speciation and Its Effect on In Vitro Cellular Iron Metabolism. PLoS One (2015) 0.78