Published in NIDA Res Monogr on January 01, 1987
Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature (1995) 6.72
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
Molecular structure of a deoxyribose-dinucleotide, sodium thymidylyl-(5' yields to 3')-thymidylate-(5') hydrate (pTpT), and a possible structural model for polythymidylate. J Mol Biol (1976) 2.08
Molecular dynamics simulations of phospholipid bilayers. J Biomol Struct Dyn (1994) 2.06
Donor-acceptor interaction and the peculiar structures of dications. J Am Chem Soc (1986) 1.67
Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1. J Pharmacol Exp Ther (1997) 1.59
Characterization of opiates, neuroleptics, and synthetic analogs at ORL1 and opioid receptors. Eur J Pharmacol (2001) 1.30
Activities of mixed NOP and mu-opioid receptor ligands. Br J Pharmacol (2007) 1.30
Crystal and molecular structure of paclitaxel (taxol). Proc Natl Acad Sci U S A (1995) 1.25
Azidothymidine: crystal structure and possible functional role of the azido group. Proc Natl Acad Sci U S A (1987) 1.19
Relationship between binding affinity and functional activity of nociceptin/orphanin FQ. Neuropeptides (1997) 1.09
Calcium antagonists High-affinity binding and inhibition of calcium transport in a clonal cell line. J Biol Chem (1982) 1.07
Two rhodamine derivatives: 9-[2-(ethoxycarbonyl)phenyl]-3,6-bis-(ethylamino)-2,7-dimethylxanthylium chloride monohydrate and 3,6-diamino-9-[2-(methoxycarbonyl)-phenyl]xanthylium chloride trihydrate. Acta Crystallogr C (2001) 1.07
Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell line. Biochemistry (1980) 1.06
A new analogue of 10-deazaaminopterin with markedly enhanced curative effects against human tumor xenografts in mice. Cancer Chemother Pharmacol (1998) 1.06
Semiempirical calculations of model oxyheme: Variation of calculated electromagnetic properties with electronic configuration and oxygen geometry. J Am Chem Soc (1977) 1.05
Diphenylhydantoin and diazepam: molecular structure similarities and steric basis of anticonvulsant activity. Science (1970) 1.03
Role of Mg2+-ATPase and a pH gradient in the storage of catecholamines in synaptic vesicles. Biochemistry (1978) 1.02
Stereochemical basis of anticonvulsant drug action. II. Molecular structure of diazepam. J Am Chem Soc (1972) 1.02
The stereochemical basis of anticonvulsant drug action. 3. The structure of procyclidine hydrochloride. Mol Pharmacol (1971) 1.01
Semiempirical calculations of model deoxyheme. Variation of calculated electromagnetic properties with electronic configuration and distance of iron from the plane. Biophys J (1978) 1.01
A Schiff base formed from sulfanilic acid and dimethylformamide. Acta Crystallogr C (1999) 1.01
The stereochemical basis of anticonvulsant drug action. IV. The crystal and molecular structure of trihexyphenidyl. J Am Chem Soc (1972) 1.01
Iron bispentazole Fe(eta5-N5)2, a theoretically predicted high-energy compound: structure, bonding analysis, metal-ligand bond strength and a comparison with the isoelectronic ferrocene. Chemistry (2001) 0.99
Construction of a 3D model of cytochrome P450 2B4. Protein Eng (1997) 0.98
Crystal and molecular structure of photodimer A of 1,3-dimethylthymine (the isomer in irradiated deoxyribonucleic acid). J Am Chem Soc (1970) 0.96
[3H]doxepin interactions with histamine H1-receptors and other sites in guinea pig and rat brain homogenates. Eur J Pharmacol (1981) 0.96
New folate analogs of the 10-deaza-aminopterin series. Basis for structural design and biochemical and pharmacologic properties. Cancer Chemother Pharmacol (1984) 0.95
Structure of a dinucleotide: thymidylyl-(5'-3')-thymidylate-5' (pTpT). Science (1973) 0.94
Quantum chemical studies of morphine-like opiate narcotics. Effect of N-substituent variations. J Med Chem (1975) 0.94
The hyperphagic effect of 3 alpha-hydroxylated pregnane steroids in male rats. Pharmacol Biochem Behav (1996) 0.93
Assessment of chemicals using a battery of neurobehavioral tests: a comparative study. Neurobehav Toxicol Teratol (1983) 0.93
Solubilization and Characterization of Histamine H1 receptors in brain. J Biol Chem (1982) 0.93
Determination of activity for nociceptin in the mouse vas deferens. Eur J Pharmacol (1996) 0.92
L-type cardiac calcium channels in doxorubicin cardiomyopathy in rats morphological, biochemical, and functional correlations. J Clin Invest (1991) 0.92
X-ray diffraction studies of rennin crystals. Philos Trans R Soc Lond B Biol Sci (1970) 0.92
Interaction of an amphiphilic peptide with a phospholipid bilayer surface by molecular dynamics simulation study. J Biomol Struct Dyn (1995) 0.91
Crystal structure of methionine-enkephalin. Biochem Biophys Res Commun (1986) 0.91
Comparison of behavioral and central BDZ binding profile in three rat lines. Pharmacol Biochem Behav (1992) 0.91
New folate analogs of the 10-deaza-aminopterin series. Further evidence for markedly increased antitumor efficacy compared with methotrexate in ascitic and solid murine tumor models. Cancer Chemother Pharmacol (1984) 0.90
Evidence that an ATPase and a protonmotive force function in the transport of acetylcholine into storage vesicles. J Biol Chem (1980) 0.90
The in vitro pharmacological characterization of naloxone benzoylhydrazone. Eur J Pharmacol (1995) 0.89
Triiodothyronine: the 3'iodine is proximal to the -ring in crystal structure conformation. Science (1972) 0.88
Oxidation of carbon tetrachloride, bromotrichloromethane, and carbon tetrabromide by rat liver microsomes to electrophilic halogens. Life Sci (1982) 0.88
Molecular determinants of non-specific recognition of delta, mu, and kappa opioid receptors. Bioorg Med Chem (2001) 0.87
10-Ethyl-10-deaza-aminopterin: structural design and biochemical, pharmacologic, and antitumor properties. NCI Monogr (1987) 0.87
3D modeling, ligand binding and activation studies of the cloned mouse delta, mu; and kappa opioid receptors. Protein Eng (1999) 0.87
Theoretical study of the product specificity in the hydroxylation of camphor, norcamphor, 5,5-difluorocamphor, and pericyclocamphanone by cytochrome P-450cam. J Biol Chem (1988) 0.87
Energy utilization in the uptake of catecholamines by synaptic vesicles and adrenal chromaffin granules. Brain Res (1977) 0.87
Homology modeling and substrate binding study of human CYP4A11 enzyme. Proteins (1999) 0.86
Differentiation of delta, mu, and kappa opioid receptor agonists based on pharmacophore development and computed physicochemical properties. J Comput Aided Mol Des (2001) 0.86
Nociceptin in vitro biotransformation in human blood. Peptides (1996) 0.86
A 3D model of the delta opioid receptor and ligand-receptor complexes. Protein Eng (1996) 0.86
Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory. Eur J Pharmacol (2001) 0.86
Tryptophanyl-tRNA synthetase from Bacillus subtilis. Characterization and role of hydrophobicity in substrate recognition. J Biol Chem (1989) 0.85
Cyclophosphamide structure. Molecular structure of 4-ketocyclophosphamide. J Am Chem Soc (1973) 0.85
Evidence for an NMDA receptor subunit in human keratinocytes and rat cardiocytes. Eur J Pharmacol (1994) 0.85
Structural determinants of opioid activity in the orvinols and related structures: ethers of orvinol and isoorvinol. J Med Chem (2000) 0.85
Crystal structure of leucine-enkephalin. Nature (1984) 0.85
A crystalline proteinase (peptidase A) from Penicillium janthinellum: preliminary X-ray data. J Mol Biol (1969) 0.85
Development of a 3D pharmacophore for nonspecific ligand recognition of alpha1, alpha2, alpha3, alpha5, and alpha6 containing GABA(A)/benzodiazepine receptors. Bioorg Med Chem (2000) 0.85
Activated cyclophosphamide anticancer drugs: molecular structures of cis- and trans-4-hydroperoxyisophosphamides. J Med Chem (1983) 0.85
Energy conformation study of Met-enkephalin and its D-Ala2 analogue and their resemblance to rigid opiates. Proc Natl Acad Sci U S A (1978) 0.85
The reaction of atomic oxygen with methanethiol. A theoretical study of the structures and the potential energy surface. Chem Phys Lett (1993) 0.85
Interactions between toluene and alcohol. Pharmacol Biochem Behav (1985) 0.85
Evidence for mu1-opioid receptor involvement in fentanyl-mediated respiratory depression. Eur J Pharmacol (1996) 0.84
Intravenous self-administration of ethanol and acetaldehyde by rats. Yakubutsu Seishin Kodo (1985) 0.84
Investigation of the proton-assisted pathway to formation of the catalytically active, ferryl species of P450s by molecular dynamics studies of P450eryF. J Am Chem Soc (1996) 0.84
Letter: Electronic structure and electric field gradients in oxyhemoglobin and -cytochrome P-450 model compounds. J Am Chem Soc (1975) 0.84
Molecular dynamics simulations of P450 BM3--examination of substrate-induced conformational change. J Biomol Struct Dyn (1999) 0.84
New folate analogs of the 10-deaza-aminopterin series: markedly increased antitumor activity of the 10-ethyl analog compared to the parent compound and methotrexate against some human tumor xenografts in nude mice. Cancer Treat Rep (1985) 0.84
Modulation of enkephalin release by nociceptin (orphanin FQ). Eur J Pharmacol (1997) 0.83
Hallucinogenic compounds and swimming response. J Pharmacol Exp Ther (1968) 0.83
Molecular dynamics simulation of anesthetic-phospholipid bilayer interactions. J Biomol Struct Dyn (1995) 0.83
Glucosidase inhibitors: structures of deoxynojirimycin and castanospermine. J Med Chem (1993) 0.83
Molecular determinants of benzodiazepine receptor affinities and anticonvulsant activities. Mol Pharmacol (1989) 0.82
Characterization of low-energy conformational domains for Met-enkephalin. J Comput Aided Mol Des (1992) 0.82
Ranitidine hydrochloride, a polymorphic crystal form. Acta Crystallogr C (2000) 0.82
Crystal structure of an extended-conformation leucine-enkephalin dimer monohydrate. Life Sci (1987) 0.81