PubRank

A J Sinskey

Author PubWeight™ 130.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Oxidized redox state of glutathione in the endoplasmic reticulum. Science 1992 6.91
2 Poly-beta-hydroxybutyrate (PHB) biosynthesis in Alcaligenes eutrophus H16. Identification and characterization of the PHB polymerase gene (phbC). J Biol Chem 1989 3.79
3 Poly-beta-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16. Characterization of the genes encoding beta-ketothiolase and acetoacetyl-CoA reductase. J Biol Chem 1989 2.56
4 PHA synthase activity controls the molecular weight and polydispersity of polyhydroxybutyrate in vivo. Nat Biotechnol 1997 2.49
5 Cloning vector system for Corynebacterium glutamicum. J Bacteriol 1985 2.37
6 Overexpression and purification of the soluble polyhydroxyalkanoate synthase from Alcaligenes eutrophus: evidence for a required posttranslational modification for catalytic activity. Biochemistry 1994 1.98
7 Biosynthetic thiolase from Zoogloea ramigera. III. Isolation and characterization of the structural gene. J Biol Chem 1987 1.94
8 General organization of the genes specifically involved in the diaminopimelate-lysine biosynthetic pathway of Corynebacterium glutamicum. Mol Gen Genet 1988 1.94
9 Accumulation of the PhaP phasin of Ralstonia eutropha is dependent on production of polyhydroxybutyrate in cells. J Bacteriol 2001 1.70
10 New insight into the role of the PhaP phasin of Ralstonia eutropha in promoting synthesis of polyhydroxybutyrate. J Bacteriol 2001 1.69
11 Nucleotide sequence and organization of the upstream region of the Corynebacterium glutamicum lysA gene. Mol Microbiol 1990 1.61
12 Nitrite in human saliva. Its possible relationship to nitrosamine formation. J Natl Cancer Inst 1974 1.46
13 Protein kinase C is required for responses to T cell receptor ligands but not to interleukin-2 in T cells. Cell 1988 1.45
14 Biosynthetic thiolase from zoogloea ramigera. I. Preliminary characterization and analysis of proton transfer reaction. J Biol Chem 1987 1.44
15 Radiation-resistant mutants of Salmonella typhimurium LT2: development and characterization. J Bacteriol 1973 1.42
16 Class I and III polyhydroxyalkanoate synthases from Ralstonia eutropha and Allochromatium vinosum: characterization and substrate specificity studies. Arch Biochem Biophys 2001 1.42
17 Isolation of Zoogloea ramigera I-16-M exopolysaccharide biosynthetic genes and evidence for instability within this region. J Bacteriol 1987 1.39
18 Deoxyribonucleic acid breaks in heated Salmonella typhimurium LT-2 after exposure to nutritionally complex media. J Bacteriol 1973 1.39
19 Regulated secretion of prolactin by the mouse insulinoma cell line beta TC-3. Biotechnology (N Y) 1995 1.38
20 Isolation and characterization of indene bioconversion genes from Rhodococcus strain I24. Appl Microbiol Biotechnol 1999 1.37
21 Expression, secretion, and processing of staphylococcal nuclease by Corynebacterium glutamicum. J Bacteriol 1992 1.32
22 Lipases provide a new mechanistic model for polyhydroxybutyrate (PHB) synthases: characterization of the functional residues in Chromatium vinosum PHB synthase. Biochemistry 2000 1.29
23 Mechanistic studies on beta-ketoacyl thiolase from Zoogloea ramigera: identification of the active-site nucleophile as Cys89, its mutation to Ser89, and kinetic and thermodynamic characterization of wild-type and mutant enzymes. Biochemistry 1989 1.28
24 Immunocytochemical analysis of poly-beta-hydroxybutyrate (PHB) synthase in Alcaligenes eutrophus H16: localization of the synthase enzyme at the surface of PHB granules. J Bacteriol 1993 1.25
25 PHA synthase from chromatium vinosum: cysteine 149 is involved in covalent catalysis. Biochemistry 1999 1.23
26 Mechanistic studies on class I polyhydroxybutyrate (PHB) synthase from Ralstonia eutropha: class I and III synthases share a similar catalytic mechanism. Biochemistry 2001 1.21
27 Gene structure and expression of the Corynebacterium flavum N13 ask-asd operon. J Bacteriol 1993 1.20
28 The AP-1 site at -150 bp, but not the NF-kappa B site, is likely to represent the major target of protein kinase C in the interleukin 2 promoter. J Exp Med 1992 1.19
29 Reduction of waste product excretion via nutrient control: Possible strategies for maximizing product and cell yields on serum in cultures of mammalian cells. Biotechnol Bioeng 1986 1.19
30 Nucleotide sequence and fine structural analysis of the Corynebacterium glutamicum hom-thrB operon. Mol Microbiol 1988 1.18
31 Fine structural analysis of the Zoogloea ramigera phbA-phbB locus encoding beta-ketothiolase and acetoacetyl-CoA reductase: nucleotide sequence of phbB. Mol Microbiol 1989 1.18
32 Comparison of the efficacy of steam sterilization indicators. Appl Environ Microbiol 1979 1.17
33 Mathematical descriptions of hybridoma culture kinetics: I. Initial metabolic rates. Biotechnol Bioeng 1988 1.17
34 Proceedings: Characteristics of freeze-dried cells. Cryobiology 1973 1.17
35 Streptococcus mutans dextransucrase: a review. Adv Appl Microbiol 1978 1.16
36 Molecular cloning and nucleotide sequence of the Corynebacterium glutamicum pheA gene. J Bacteriol 1986 1.15
37 Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas. Appl Microbiol Biotechnol 1995 1.12
38 Organization and regulation of the Corynebacterium glutamicum hom-thrB and thrC loci. Mol Microbiol 1988 1.10
39 Development and validation of corynebacterium DNA microarrays. Appl Environ Microbiol 2001 1.09
40 Minimal medium recovery of heated Salmonella typhimurium LT2. J Gen Microbiol 1973 1.09
41 Ionizing radiation damage to the folded chromosome of Escherichia coli K-12: sedimentation properties of irradiated nucleoids and chromosomal deoxyribonucleic acid. J Bacteriol 1979 1.06
42 Cloning and sequencing the Lactobacillus brevis gene encoding xylose isomerase. Gene 1992 1.05
43 Structural and functional analysis of pyruvate kinase from Corynebacterium glutamicum. Appl Environ Microbiol 1994 1.05
44 Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl Environ Microbiol 1999 1.03
45 Precision of RNA separation by polyacrylamide gel electrophoresis. Anal Biochem 1970 1.03
46 Disparity between changes in mRNA abundance and enzyme activity in Corynebacterium glutamicum: implications for DNA microarray analysis. Appl Microbiol Biotechnol 2002 1.02
47 The phosphoenolpyruvate carboxylase gene of Corynebacterium glutamicum: molecular cloning, nucleotide sequence, and expression. Mol Gen Genet 1989 1.01
48 Deoxyribonucleic acid repair in a highly radiation-resistant strain of Salmonella typhimurium. J Bacteriol 1973 1.00
49 New process for reducing the nucleic acid content of yeast. Nature 1970 1.00
50 A C-terminal deletion in Corynebacterium glutamicum homoserine dehydrogenase abolishes allosteric inhibition by L-threonine. Gene 1991 1.00
51 Effect of different levels of aspartokinase on the lysine production by Corynebacterium lactofermentum. Appl Microbiol Biotechnol 1995 0.99
52 Characterization of a heat-shock process for reduction of the nucleic acid content of Candida utilis. Appl Microbiol 1971 0.99
53 Biosynthetic thiolase from Zoogloea ramigera. Evidence for a mechanism involving Cys-378 as the active site base. J Biol Chem 1991 0.98
54 Metabolic engineering--methodologies and future prospects. Trends Biotechnol 1993 0.97
55 Cloning of the pyruvate kinase gene (pyk) of Corynebacterium glutamicum and site-specific inactivation of pyk in a lysine-producing Corynebacterium lactofermentum strain. Appl Environ Microbiol 1994 0.97
56 Recent advances in the physiology and genetics of amino acid-producing bacteria. Crit Rev Biotechnol 1995 0.97
57 Transformation of T lymphocytes by the v-fos oncogene. J Immunol 1990 0.97
58 A microbiological and biochemical study of gingival crevice debris obtained from Guatemalan Mayan Indians. J Periodontol 1970 0.97
59 Reduction of nucleic acid content in Candida yeast cells by bovine pancreatic ribonuclease A treatment. Appl Microbiol 1971 0.96
60 Molecular cloning, nucleotide sequence and fine-structural analysis of the Corynebacterium glutamicum fda gene: structural comparison of C. glutamicum fructose-1,6-biphosphate aldolase to class I and class II aldolases. Mol Microbiol 1989 0.96
61 The molecular structure of the Corynebacterium glutamicum threonine synthase gene. Mol Microbiol 1990 0.95
62 Production of isoleucine by overexpression of ilvA in a Corynebacterium lactofermentum threonine producer. Appl Microbiol Biotechnol 1995 0.94
63 Characterization of Streptomyces MITKK-103, a newly isolated actinomycin X2-producer. Appl Microbiol Biotechnol 2005 0.94
64 Metabolite and isotopomer balancing in the analysis of metabolic cycles: II. Applications. Biotechnol Bioeng 1999 0.94
65 A modeling framework for the study of protein glycosylation. Biotechnol Bioeng 1996 0.93
66 Biosynthetic thiolase from Zoogloea ramigera. II. Inactivation with haloacetyl CoA analogs. J Biol Chem 1987 0.93
67 Glioblastoma cell death induced by asiatic acid. Cell Biol Toxicol 2006 0.92
68 Metabolic and physiological studies of Corynebacterium glutamicum mutants. Biotechnol Bioeng 1997 0.92
69 Distribution of dextransucrase in Streptococcus mutans and observations on the effect of soluble dextran on dextransucrase activities. Infect Immun 1977 0.92
70 Measurement of glutathione redox state in cytosol and secretory pathway of cultured cells. Methods Enzymol 1995 0.91
71 A quantitative model of diffusion bioassays. J Theor Biol 1979 0.89
72 Characterization of Lactobacillus bulgaricus Bacteriophage ch2. Appl Environ Microbiol 1988 0.89
73 Nucleotide sequence of the lysA gene of Corynebacterium glutamicum and possible mechanisms for modulation of its expression. Mol Gen Genet 1988 0.89
74 The Rhodococcus opacus PD630 heparin-binding hemagglutinin homolog TadA mediates lipid body formation. Appl Environ Microbiol 2010 0.88
75 Production of cell-derived products: virus and interferon. Ann N Y Acad Sci 1981 0.88
76 The DNA sequence and minimal replicon of the Corynebacterium glutamicum plasmid pSR1: evidence of a common ancestry with plasmids from C. diphtheriae. J Gen Microbiol 1993 0.88
77 Effect of inducible thrB expression on amino acid production in Corynebacterium lactofermentum ATCC 21799. Appl Environ Microbiol 1995 0.87
78 Effect of aeration on minimal medium recovery of heated Salmonella typhimurium. J Bacteriol 1975 0.86
79 Direct evidence for a xylose metabolic pathway in Saccharomyces cerevisiae. Biotechnol Bioeng 1986 0.85
80 Activation of nitrosomorpholine and nitrosopyrrolidine to bacterial mutagens. Mutat Res 1974 0.85
81 Effects of inhibitors of protein, RNA and DNA synthesis on heat-injured Salmonella typhimurium LT2. J Gen Microbiol 1976 0.85
82 Application of radiolabeled tracers to biocatalytic flux analysis. Eur J Biochem 2001 0.84
83 Apoptosis in batch cultures of Chinese hamster ovary cells. Biotechnol Bioeng 1999 0.84
84 Growth factor and bcl-2 mediated survival during abortive proliferation of hybridoma cell line. Biotechnol Bioeng 1998 0.84
85 Engineering an indene bioconversion process for the production of cis-aminoindanol: a model system for the production of chiral synthons. Appl Microbiol Biotechnol 2002 0.83
86 Degradation of ribonucleic acid in Candida lipolytica: extraction of ribonucleic acid degrading enzymes. Biotechnol Bioeng 1972 0.83
87 Measurement and synthesis of insoluble and soluble dextran by Streptococcus mutans. J Dent Res 1977 0.83
88 Flux through the tetrahydrodipicolinate succinylase pathway is dispensable for L-lysine production in Corynebacterium glutamicum. Appl Microbiol Biotechnol 1999 0.82
89 [Synthesis of 3-hydroxybutyrate-CO-4-hydroxybutyrate copolymers by hydrogen-oxidizing bacteria]. Prikl Biokhim Mikrobiol 2012 0.82
90 Sequence of the Corynebacterium glutamicum pyruvate carboxylase gene. Appl Microbiol Biotechnol 1998 0.82
91 Effect of shear on the death of two strains of mammalian tissue cells. Biotechnol Bioeng 1971 0.82
92 Oxidation of L-glucose by a Pseudomonad. Biochim Biophys Acta 1979 0.82
93 Ionizing radiation damage to the folded chromosome of Escherichia coli K-12: repair of double-strand breaks in deoxyribonucleic acid. J Bacteriol 1979 0.81
94 Purification and properties of oxaloacetate decarboxylase from Corynebacterium glutamicum. Antonie Van Leeuwenhoek 1995 0.81
95 Characterization of IS1676 from Rhodococcus erythropolis SQ1. Appl Microbiol Biotechnol 1999 0.81
96 Optimization in the recovery of a labile intracellular enzyme. Biotechnol Bioeng 1974 0.80
97 Biosynthetic thiolase from Zoogloea ramigera. Mutagenesis of the putative active-site base Cys-378 to Ser-378 changes the partitioning of the acetyl S-enzyme intermediate. J Biol Chem 1992 0.80
98 Large-scale production of mammalian cells and their products: engineering principles and barriers to scale-up. Ann N Y Acad Sci 1983 0.80
99 Redirection of carbon flux to lysine in a recombinant of Corynebacterium lactofermentum ATCC 21799 by limited supply of pantothenate. J Biosci Bioeng 1999 0.79
100 Continuous culture studies on the growth and physiology of Streptococcus mutans. J Dent Res 1976 0.79
101 A new macromolecular inhibitor of yeast ribonuclease mediated through purine nucleotides. Biochim Biophys Acta 1972 0.79
102 Mathematical descriptions of hybridoma culture kinetics: II. The relationship between thiol chemistry and the degradation of serum activity. Biotechnol Bioeng 1989 0.79
103 Metabolic redirection of carbon flow toward isoleucine by expressing a catabolic threonine dehydratase in a threonine-overproducing Corynebacterium glutamicum. Appl Microbiol Biotechnol 2001 0.78
104 The effect of protein synthesis inhibitors on the glycosylation site occupancy of recombinant human prolactin. Cytotechnology 1994 0.78
105 Puridication and properties of an intracellular ribonuclease from Candida lipolytica. Biochim Biophys Acta 1975 0.78
106 Extension of Sp2/0 hybridoma cell viability through interleukin-6 supplementation. Biotechnol Bioeng 1997 0.78
107 Microparticles prepared from biodegradable polyhydroxyalkanoates as matrix for encapsulation of cytostatic drug. J Mater Sci Mater Med 2013 0.78
108 Use of regulated secretion in protein production from animal cells: an evaluation with the AtT-20 model cell line. Biotechnol Bioeng 1990 0.77
109 Morphology of yeast cell wall as affected by genetic manipulation of beta(1 --> 6) glycosidic linkage. Biotechnol Bioeng 1986 0.77
110 Genetic mapping of mutations in a highly radiation-resistant mutant of Salmonella typhimurium LT2. J Bacteriol 1982 0.76
111 Biotechnology in food production and processing. Science 1985 0.76
112 Collection of microbial cells. Adv Appl Microbiol 1970 0.76
113 Kinetics of human beta interferon production under different temperature conditions. J Interferon Res 1982 0.76
114 Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) containing a predominant amount of 3-hydroxyvalerate by engineered Escherichia coli expressing propionate-CoA transferase. J Appl Microbiol 2012 0.76
115 Cell engineering and molecular pharming for biopharmaceuticals. Open Med Chem J 2008 0.75
116 Metabolic engineering of Corynebacterium glutamicum. Ann N Y Acad Sci 1994 0.75
117 Acrylate fermentations. Basic Life Sci 1981 0.75
118 An in vitro assay to measure early calcium loss from surface enamel. J Dent Res 1974 0.75
119 Neutralization of the bactericidal effect of cocoa powder on salmonellae by casein. J Appl Bacteriol 1977 0.75
120 Kinetics of the bleomycin A2 damage in vivo to the folded chromosome of Escherichia coli. Chem Biol Interact 1983 0.75
121 Heat-induced damage to the bacterial chromosome and its repair. Soc Appl Bacteriol Symp Ser 1984 0.75
122 Instrumentation for process control in cell culture. Adv Appl Microbiol 1981 0.75
123 Genetic engineering for food and additives. Soc Appl Bacteriol Symp Ser 1983 0.75
124 Application of ultrafiltration for enzyme retention during continuous enzymatic reaction. Biotechnol Bioeng 1970 0.75
125 Molecular cloning of aldolases for synthetic applications. Ann N Y Acad Sci 1990 0.75
126 Repair of lesions induced in human liver cell DNA by N-nitroso compounds as measured by the bromodeoxyuridine photolysis method. Mutat Res 1974 0.75
127 The effect of different genetic properties of Salmonella typhimurium on the determination of stabilities and mutagenic concentrations of chemical carcinogens using the diffusion bioassay. Mutat Res 1983 0.75
128 Quantitative determination of half-lifetimes and mutagenic concentrations of chemical carcinogens using a diffusion bioassay. Mutat Res 1980 0.75
129 DNA breaks in rifampin-treated Salmonella typhimurium LT2 after exposure to nutritionally complex media. Nature 1974 0.75
130 Process characteristics of cell lysis mutants of Saccharomyces cerevisiae. Biotechnol Bioeng 1979 0.75
131 Recovery of biological materials through ultrafiltration. Biotechnol Bioeng 1969 0.75