Published in J Orthop on March 20, 2017
Bone: formation by autoinduction. Science (1965) 13.34
Prevalence, complications, and hospital charges associated with use of bone-morphogenetic proteins in spinal fusion procedures. JAMA (2009) 4.07
Safety and effectiveness of recombinant human bone morphogenetic protein-2 for spinal fusion: a meta-analysis of individual-participant data. Ann Intern Med (2013) 4.02
Complications associated with single-level transforaminal lumbar interbody fusion. Spine J (2009) 2.99
Clinical and radiographic outcomes of anterior lumbar interbody fusion using recombinant human bone morphogenetic protein-2. Spine (Phila Pa 1976) (2002) 2.74
Anterior lumbar interbody fusion using rhBMP-2 with tapered interbody cages. J Spinal Disord Tech (2002) 2.54
A comprehensive review of the safety profile of bone morphogenetic protein in spine surgery. Neurosurgery (2008) 2.39
Transforaminal lumbar interbody fusion: clinical and radiographic results and complications in 100 consecutive patients. J Spinal Disord Tech (2005) 2.27
Off-label use of bone morphogenetic proteins in the United States using administrative data. Spine (Phila Pa 1976) (2010) 2.24
Increased swelling complications associated with off-label usage of rhBMP-2 in the anterior cervical spine. Spine (Phila Pa 1976) (2006) 2.19
A prospective, randomized, controlled cervical fusion study using recombinant human bone morphogenetic protein-2 with the CORNERSTONE-SR allograft ring and the ATLANTIS anterior cervical plate. Spine (Phila Pa 1976) (2003) 1.97
Safety of transforaminal lumbar interbody fusion and intervertebral recombinant human bone morphogenetic protein-2. J Neurosurg Spine (2005) 1.93
High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo. Tissue Eng Part A (2011) 1.87
Posterior lumbar interbody fusion using recombinant human bone morphogenetic protein type 2 with cylindrical interbody cages. Spine J (2004) 1.84
Perioperative complications in transforaminal lumbar interbody fusion versus anterior-posterior reconstruction for lumbar disc degeneration and instability. J Spinal Disord Tech (2006) 1.75
Recombinant human bone morphogenetic protein-2-induced radiculitis in elective minimally invasive transforaminal lumbar interbody fusions: a series review. Spine (Phila Pa 1976) (2009) 1.59
Complications with the use of bone morphogenetic protein 2 (BMP-2) in spine surgery. Spine J (2014) 1.52
RhBMP-2 versus iliac crest bone graft for lumbar spine fusion: a randomized, controlled trial in patients over sixty years of age. Spine (Phila Pa 1976) (2008) 1.35
Complications due to the use of BMP/INFUSE in spine surgery: The evidence continues to mount. Surg Neurol Int (2013) 1.27
Occipitocervical fusion using recombinant human bone morphogenetic protein-2: adverse effects due to tissue swelling and seroma. Spine (Phila Pa 1976) (2008) 1.24
Cytokine-mediated inflammatory reaction following posterior cervical decompression and fusion associated with recombinant human bone morphogenetic protein-2: a case study. Spine (Phila Pa 1976) (2010) 1.20
Formation of painful seroma and edema after the use of recombinant human bone morphogenetic protein-2 in posterolateral lumbar spine fusions. Neurosurgery (2010) 1.08
BMP induced inflammation: a comparison of rhBMP-7 and rhBMP-2. J Orthop Res (2012) 1.07
Adverse events after recombinant human BMP2 in nonspinal orthopaedic procedures. Clin Orthop Relat Res (2012) 1.01
BMP2-induced inflammation can be suppressed by the osteoinductive growth factor NELL-1. Tissue Eng Part A (2013) 0.99
Activin and bone morphogenetic proteins induce calcitonin gene-related peptide in embryonic sensory neurons in vitro. Mol Cell Neurosci (1999) 0.97
Inflammatory characteristics of rhBMP-2 in vitro and in an in vivo rodent model. Spine (Phila Pa 1976) (2011) 0.95
Neurogenic substance P stimulates osteogenesis in vitro. Peptides (1997) 0.95
BMP-2/PLGA delayed-release microspheres composite graft, selection of bone particulate diameters, and prevention of aseptic inflammation for bone tissue engineering. Ann Biomed Eng (2010) 0.93
Bone morphogenetic proteins: basic concepts. Neurosurg Focus (2002) 0.91
A Review of the Clinical Side Effects of Bone Morphogenetic Protein-2. Tissue Eng Part B Rev (2016) 0.87
Statins decrease expression of the proinflammatory neuropeptides calcitonin gene-related peptide and substance P in sensory neurons. J Pharmacol Exp Ther (2007) 0.86
Are BMPs involved in normal nerve and following transection?: a pilot study. Clin Orthop Relat Res (2009) 0.86
Delivery of bone morphogenetic protein-2 and substance P using graphene oxide for bone regeneration. Int J Nanomedicine (2014) 0.85
Calcitonin gene related peptide enhances bone colony development in vitro. Clin Orthop Relat Res (1997) 0.83
BMP-2 adverse reactions treated with human dose equivalent dexamethasone in a rodent model of soft-tissue inflammation. Spine (Phila Pa 1976) (2013) 0.81
Histological investigation of osteoinductive properties of rh-BMP2 in a rat calvarial bone defect model. J Craniomaxillofac Surg (2004) 0.81
RhBMP-2 use in lumbar fusion surgery is associated with transient immediate post-operative leg pain. Eur Spine J (2011) 0.81
Calcitonin gene-related peptide stimulates BMP-2 expression and the differentiation of human osteoblast-like cells in vitro. Acta Pharmacol Sin (2013) 0.80
Bone morphogenetic protein-2 counterregulates interleukin-18 mRNA and protein in MC3T3-E1 mouse osteoblastic cells. Connect Tissue Res (2006) 0.80
Transforaminal lumbar interbody fusion and posterior lumbar interbody fusion utilizing BMP-2 in treatment of degenerative spondylolisthesis: neither safe nor cost effective. Surg Neurol Int (2013) 0.80
A review of the current published spinal literature regarding bone morphogenetic protein-2: an insight into potential bias. Curr Rev Musculoskelet Med (2014) 0.79
Effectiveness and safety of recombinant human bone morphogenetic protein-2 versus local bone graft in primary lumbar interbody fusions. Spine (Phila Pa 1976) (2014) 0.78
Exaggerated inflammatory environment decreases BMP-2/ACS-induced ectopic bone mass in a rat model: implications for clinical use of BMP-2. Osteoarthritis Cartilage (2014) 0.78
A dual delivery of substance P and bone morphogenetic protein-2 for mesenchymal stem cell recruitment and bone regeneration. Tissue Eng Part A (2015) 0.77
Acute epidural lipedema: a novel entity and potential complication of bone morphogenetic protein use in lumbar spine fusion. Spine J (2013) 0.77