RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury.

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Published in Sci Transl Med on April 19, 2017

Authors

Julius C Fischer1, Michael Bscheider1, Gabriel Eisenkolb1,2, Chia-Ching Lin1, Alexander Wintges1, Vera Otten1, Caroline A Lindemans3,4, Simon Heidegger1, Martina Rudelius5, Sébastien Monette6, Kori A Porosnicu Rodriguez2, Marco Calafiore4, Sophie Liebermann2, Chen Liu7, Siegfried Weiss8, Siegfried Weiss9, Ulrich Kalinke10, Jürgen Ruland11,12,13, Christian Peschel1, Yusuke Shono2, Melissa Docampo2, Enrico Velardi14, Robert R Jenq4, Alan M Hanash4, Jarrod A Dudakov15, Tobias Haas1, Marcel R M van den Brink16, Hendrik Poeck17,2

Author Affiliations

1: III. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
2: Department of Immunology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
3: Pediatric Blood and Bone Marrow Transplant Program, University Medical Center Utrecht, Utrecht, Netherlands.
4: Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
5: Institute of Pathology, University of Wuerzburg and Comprehensive Cancer Center Mainfranken, Wuerzburg, Germany.
6: Tri-Institutional Laboratory of Comparative Pathology, Memorial Sloan Kettering Cancer Center, Rockefeller University, and Weill Cornell Medical College, New York, NY 10065, USA.
7: Department of Pathology and Laboratory Medicine, New Jersey Medical School and Robert Wood Johnson Medical School, Rutgers University, Newark, NJ 08903, USA.
8: Molecular Immunology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany;
9: Molecular Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
10: Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany.
11: Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
12: German Cancer Consortium (DKTK), Heidelberg, Germany.
13: German Center for Infection Research (DZIF), partner site Munich, Munich, Germany.
14: Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.
15: Department of Medicine and Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
16: Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.
17: III. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany. hendrik.poeck@tum.de m-van-den-brink@ski.mskcc.org.

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