Toll-Like Receptor 4-Myeloid Differentiation Primary Response Gene 88 Pathway Is Involved in the Inflammatory Development of Polymyositis by Mediating Interferon-γ and Interleukin-17A in Humans and Experimental Autoimmune Myositis Mouse Model.

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell (2006) 33.94

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells. Nat Immunol (2002) 7.28

Polymyositis and dermatomyositis. Lancet (2003) 7.24

IL-10: the master regulator of immunity to infection. J Immunol (2008) 6.11

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells. Nature (2011) 3.38

Structure and function of Toll receptors and their ligands. Annu Rev Biochem (2007) 3.30

TLR signaling. Curr Top Microbiol Immunol (2006) 3.22

119th ENMC international workshop: trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body myositis, 10-12 October 2003, Naarden, The Netherlands. Neuromuscul Disord (2004) 2.85

HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease. Nat Rev Rheumatol (2012) 2.75

T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt. Nat Immunol (2010) 2.68

T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells. Proc Natl Acad Sci U S A (2003) 2.34

TLR-dependent T cell activation in autoimmunity. Nat Rev Immunol (2011) 1.88

Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling. J Immunol (2004) 1.58

CD4⁺T cells: differentiation and functions. Clin Dev Immunol (2012) 1.56

A comparison of 129S2/SvHsd and C57BL/6JOlaHsd mice on a test battery assessing sensorimotor, affective and cognitive behaviours: implications for the study of genetically modified mice. Behav Brain Res (2001) 1.51

Inflammatory muscle diseases: a critical review on pathogenesis and therapies. Curr Opin Pharmacol (2010) 1.30

Expression of functional Toll-like receptors by salivary gland epithelial cells: increased mRNA expression in cells derived from patients with primary Sjögren's syndrome. Clin Exp Immunol (2007) 1.17

Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation. Immunity (2010) 1.15

Role of cytokines and chemokines in idiopathic inflammatory myopathies. Curr Opin Rheumatol (2009) 1.14

The myositis autoantibody phenotypes of the juvenile idiopathic inflammatory myopathies. Medicine (Baltimore) (2013) 1.10

HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies. Arthritis Rheum (2006) 1.00

Interleukin-18 overexpression as a hallmark of the activity of autoimmune inflammatory myopathies. Clin Exp Immunol (2006) 0.96

Chemokines in idiopathic inflammatory myopathies. Front Biosci (2008) 0.96

Role of regulatory T cells in a new mouse model of experimental autoimmune myositis. Am J Pathol (2009) 0.95

The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation. Mediators Inflamm (2016) 0.92

Cytokines in immune-mediated inflammatory myopathies: cellular sources, multiple actions and therapeutic implications. Clin Exp Immunol (2014) 0.90

Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. Ann Rheum Dis (2015) 0.89

Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis. Clin Rheumatol (2009) 0.87

Myosin-induced autoimmune polymyositis in the rat. J Neurol Sci (1997) 0.85

Toll-like receptors promote inflammation in idiopathic inflammatory myopathies. J Neuropathol Exp Neurol (2012) 0.85

205th ENMC International Workshop: Pathology diagnosis of idiopathic inflammatory myopathies part II 28-30 March 2014, Naarden, The Netherlands. Neuromuscul Disord (2014) 0.85

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. Genes Immun (2015) 0.84

Prevalence and clinical characteristics of adult polymyositis and dermatomyositis; data from a large and unselected Norwegian cohort. Ann Rheum Dis (2014) 0.84

Th1, Th2, and Th17 Cytokine Involvement in Thyroid Associated Ophthalmopathy. Dis Markers (2015) 0.83

Mathematical modeling reveals kinetics of lymphocyte recirculation in the whole organism. PLoS Comput Biol (2014) 0.83

Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4. Int Immunol (2015) 0.82

HMGB1 expression and muscle regeneration in idiopathic inflammatory myopathies and degenerative joint diseases. J Muscle Res Cell Motil (2015) 0.81

Innate immunity in myasthenia gravis thymus: pathogenic effects of Toll-like receptor 4 signaling on autoimmunity. J Autoimmun (2014) 0.80

Toll-like receptor 4 mediates endothelial cell activation through NF-κB but is not associated with endothelial dysfunction in patients with rheumatoid arthritis. PLoS One (2014) 0.79

Phenotypes of Peripheral Blood Lymphocytes and Cytokine Expression in Polymyositis and Dermatomyositis before Treatment and after Clinical Remission. Clin Med Insights Arthritis Musculoskelet Disord (2012) 0.77

[The expression and significance of TLR4, MyD88 and NF-κB mRNA in mouse lymph node of experimental autoimmune myositis]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2012) 0.77

[Lymphocyte trafficking and immunesurveillance]. Nihon Rinsho Meneki Gakkai Kaishi (2006) 0.77

CD4+ and CD8+ CD28(null) T Cells Are Cytotoxic to Autologous Muscle Cells in Patients With Polymyositis. Arthritis Rheumatol (2016) 0.77

Idiopathic inflammatory myopathies-a review. Clin Rheumatol (2015) 0.76

Development of an improved animal model of experimental autoimmune myositis. Int J Clin Exp Pathol (2015) 0.76

Correlation between serum levels of IL-15 and IL-17 in patients with idiopathic inflammatory myopathies. Scand J Rheumatol (2014) 0.76

Diagnosis and classification of idiopathic inflammatory myopathies. J Intern Med (2016) 0.76

Cell Membrane-bound TLR2 and TLR4: Potential Predictors of Active Systemic Lupus Erythematosus and Lupus Nephritis. J Rheumatol (2016) 0.76

Association of HLA-DRB1 alleles with polymyositis/dermatomyositis in northern Chinese Hans. Chin Med Sci J (2002) 0.76

213th ENMC International Workshop: Outcome measures and clinical trial readiness in idiopathic inflammatory myopathies, Heemskerk, The Netherlands, 18-20 September 2015. Neuromuscul Disord (2016) 0.76

Expression of T helper type 17 (Th17)-associated cytokines and toll-like receptor 4 and their correlation with Foxp3 positive cells in rectal biopsies of horses with clinical signs of inflammatory bowel disease. Vet J (2015) 0.76

New developments in genetics of myositis. Curr Opin Rheumatol (2016) 0.75

The progress of telestroke in China. Stroke Vasc Neurol (2017) 0.75

Ginsenoside Rd Protects Against Cerebral Ischemia-Reperfusion Injury Via Decreasing the Expression of the NMDA Receptor 2B Subunit and its Phosphorylated Product. Neurochem Res (2016) 0.75