The effects of reduced rpd3 levels on fly physiology.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28447071)

Published in Nutr Healthy Aging on March 31, 2017

Authors

Jared K Woods1, Tahereh Ziafazeli1,2, Blanka Rogina1,3

Author Affiliations

1: Department of Genetics & Genome Sciences, School of Medicine, University of Connecticut Health, Farmington, CT, USA.
2: Present address: Department of Pediatrics, Division of Pediatric Endocrinology, Faculty of Health Sciences, McMaster University, ON, Canada.
3: Institute for Systems Genomics, School of Medicine, University of Connecticut Health, Farmington, CT, USA.

Articles cited by this

Regulation of cellular metabolism by protein lysine acetylation. Science (2010) 10.55

Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci U S A (2004) 9.25

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug. Nat Biotechnol (2007) 6.16

Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proc Natl Acad Sci U S A (2005) 5.34

Increase in activity during calorie restriction requires Sirt1. Science (2005) 4.90

The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J Biol (2003) 4.85

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev (1999) 3.41

Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogaster. Aging Cell (2008) 2.97

Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. Science (2002) 2.87

Histone deacetylases specifically down-regulate p53-dependent gene activation. J Biol Chem (2000) 2.67

Life extension in Drosophila by feeding a drug. Proc Natl Acad Sci U S A (2002) 2.57

Regulation of intermediary metabolism by protein acetylation. Trends Biochem Sci (2010) 2.36

High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO. Physiol Genomics (2006) 2.18

Behavioral, physical, and demographic changes in Drosophila populations through dietary restriction. Aging Cell (2005) 2.07

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease. Hum Mol Genet (2008) 2.05

Promoting health and longevity through diet: from model organisms to humans. Cell (2015) 1.80

Metabolic reserves and evolved stress resistance in Drosophila melanogaster. Physiol Zool (1998) 1.67

Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. Mol Biol Cell (1999) 1.66

Long-lived Indy and calorie restriction interact to extend life span. Proc Natl Acad Sci U S A (2009) 1.63

Mutational analysis of a histone deacetylase in Drosophila melanogaster: missense mutations suppress gene silencing associated with position effect variegation. Genetics (2000) 1.50

Evolutionary biology of starvation resistance: what we have learned from Drosophila. J Evol Biol (2007) 1.46

The functional costs and benefits of dietary restriction in Drosophila. Aging Cell (2007) 1.33

Comparative transcriptional profiling identifies takeout as a gene that regulates life span. Aging (Albany NY) (2010) 1.27

Erasers of histone acetylation: the histone deacetylase enzymes. Cold Spring Harb Perspect Biol (2014) 1.18

Diet, metabolism and lifespan in Drosophila. Exp Gerontol (2005) 1.17

dSir2 mediates the increased spontaneous physical activity in flies on calorie restriction. Aging (Albany NY) (2009) 1.07

Distinct biological epochs in the reproductive life of female Drosophila melanogaster. Mech Ageing Dev (2007) 1.07

Increased mitochondrial biogenesis preserves intestinal stem cell homeostasis and contributes to longevity in Indy mutant flies. Aging (Albany NY) (2014) 0.94

The effects of age on radiation resistance and oxidative stress in adult Drosophila melanogaster. Radiat Res (2008) 0.87

Determination of the spontaneous locomotor activity in Drosophila melanogaster. J Vis Exp (2014) 0.86

Heart-specific Rpd3 downregulation enhances cardiac function and longevity. Aging (Albany NY) (2015) 0.81

The effects of Rpd3 on fly metabolism, health, and longevity. Exp Gerontol (2016) 0.80

RPD3 histone deacetylase and nutrition have distinct but interacting effects on Drosophila longevity. Aging (Albany NY) (2015) 0.79

Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration. Curr Neuropharmacol (2016) 0.78

Rpd3 interacts with insulin signaling in Drosophila longevity extension. Aging (Albany NY) (2016) 0.77

dSir2 and fly mobility. Cell Cycle (2010) 0.77

Articles by these authors

The effects of Rpd3 on fly metabolism, health, and longevity. Exp Gerontol (2016) 0.80