Published in Naunyn Schmiedebergs Arch Pharmacol on September 01, 1988
Membrane hyperpolarization inhibits agonist-induced synthesis of inositol 1,4,5-trisphosphate in rabbit mesenteric artery. J Physiol (1992) 2.20
Ion channel modulation by NS 1619, the putative BKCa channel opener, in vascular smooth muscle. Br J Pharmacol (1994) 1.60
Differences between the effects of cromakalim and nifedipine on agonist-induced responses in rabbit aorta. Br J Pharmacol (1991) 1.29
The action of diazoxide and minoxidil sulphate on rat blood vessels: a comparison with cromakalim. Br J Pharmacol (1990) 1.26
Effects of pinacidil on contractile proteins in high K(+)-treated intact, and in beta-escin-treated skinned smooth muscle of the rabbit mesenteric artery. Br J Pharmacol (1991) 0.97
Smooth muscle K+ channel openers; their pharmacology and clinical potential. Pflugers Arch (1989) 0.97
Pharmacology of the potassium channel openers. Cardiovasc Drugs Ther (1995) 0.93
Responses to vasodilator drugs on pulmonary artery preparations from pulmonary hypertensive rats. Br J Pharmacol (1992) 0.90
Effects of several potassium channel openers and glibenclamide on the uterus of the rat. Br J Pharmacol (1990) 0.90
Pinacidil inhibits neuromuscular transmission indirectly in the guinea-pig and rabbit mesenteric arteries. Br J Pharmacol (1990) 0.88
In vitro studies on the mode of action of pinacidil. Drugs (1988) 0.81
Tissue selectivity and spasmogen selectivity of relaxant drugs in airway and pulmonary vascular smooth muscle contracted by PGF2 alpha or endothelin. Br J Pharmacol (1991) 0.78
Electrocardiographic interactions between pinacidil, a potassium channel opener and class I antiarrhythmic agents in guinea-pig isolated perfused heart. Br J Pharmacol (1995) 0.77
Effects of pinacidil on arterial and venous resistances and mean circulatory filling pressure in rats. Br J Pharmacol (1995) 0.75
Effects of atrial natriuretic peptide and nitroprusside on isolated pulmonary resistance and conduit arteries from rats with pulmonary hypertension. Br J Pharmacol (1993) 0.75
Nicorandil stimulates a Na(+)/Ca(2+) exchanger by activating guanylate cyclase in guinea pig cardiac myocytes. Pflugers Arch (2015) 0.75
K+ is an endothelium-derived hyperpolarizing factor in rat arteries. Nature (1998) 6.29
Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein. Br J Pharmacol (1986) 4.75
The effects of BRL 34915 and nicorandil on electrical and mechanical activity and on 86Rb efflux in rat blood vessels. Br J Pharmacol (1986) 3.68
Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol (1988) 3.66
Orexin A activates locus coeruleus cell firing and increases arousal in the rat. Proc Natl Acad Sci U S A (1999) 3.42
Effect of apamin on responses to BRL 34915, nicorandil and other relaxants in the guinea-pig taenia caeci. Br J Pharmacol (1986) 2.89
Evidence that the spasmogenic action of tetraethylammonium in guinea-pig trachealis is both direct and dependent on the cellular influx of calcium ion. Br J Pharmacol (1983) 2.84
Endothelium-derived hyperpolarizing factor: a new endogenous inhibitor from the vascular endothelium. Trends Pharmacol Sci (1988) 2.79
The pharmacology of ATP-sensitive potassium channels. Annu Rev Pharmacol Toxicol (1993) 2.64
Some effects of sodium nitroprusside, methoxyverapamil (D600) and nifedipine on rat portal vein. Br J Pharmacol (1980) 2.52
Simultaneous long-term recording of the mechanical and intracellular electrical activity of smooth muscles. J Pharmacol Methods (1980) 2.37
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Characterization of an apamin-sensitive small-conductance Ca(2+)-activated K(+) channel in porcine coronary artery endothelium: relevance to EDHF. Br J Pharmacol (2002) 1.94
Induction cisplatin/vinblastine and irradiation vs. irradiation in unresectable squamous cell lung cancer: failure patterns by cell type in RTOG 88-08/ECOG 4588. Radiation Therapy Oncology Group. Eastern Cooperative Oncology Group. Int J Radiat Oncol Biol Phys (1997) 1.65
Ion channel modulation by NS 1619, the putative BKCa channel opener, in vascular smooth muscle. Br J Pharmacol (1994) 1.60
Lean body mass as a predictor of drug dosage. Implications for drug therapy. Clin Pharmacokinet (1994) 1.59
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A. J Pharmacol Exp Ther (2000) 1.56
Further investigation of endothelium-derived hyperpolarizing factor (EDHF) in rat hepatic artery: studies using 1-EBIO and ouabain. Br J Pharmacol (1999) 1.55
KATP--fact or artefact? New thoughts on the mode of action of the potassium channel openers. Cardiovasc Res (1994) 1.54
Role of gap junctions in the responses to EDHF in rat and guinea-pig small arteries. Br J Pharmacol (1999) 1.53
Endothelium-dependent effects of acetylcholine in rat aorta: a comparison with sodium nitroprusside and cromakalim. Br J Pharmacol (1988) 1.51
Characterization of potassium currents modulated by BRL 38227 in rat portal vein. Br J Pharmacol (1992) 1.50
The relaxant action of BRL 34915 in rat uterus. Br J Pharmacol (1987) 1.45
Evidence that the mechanism of the inhibitory action of pinacidil in rat and guinea-pig smooth muscle differs from that of glyceryl trinitrate. Br J Pharmacol (1987) 1.41
Classification of patients with disseminated cancer of the breast. Cancer (1969) 1.40
Evaluation of the potassium channel activator cromakalim (BRL 34915) as a bronchodilator in the guinea-pig: comparison with nifedipine. Br J Pharmacol (1988) 1.40
Effects of methyl beta-cyclodextrin on EDHF responses in pig and rat arteries; association between SK(Ca) channels and caveolin-rich domains. Br J Pharmacol (2007) 1.39
Mithramycin treatment of hypercalcemia. Cancer (1970) 1.38
A comparison of several calcium antagonists on uterine, vascular and cardiac muscles from the rat. Br J Pharmacol (1985) 1.38
Endothelium-derived hyperpolarizing factor--a critical appraisal. Prog Drug Res (1998) 1.35
Levcromakalim may induce a voltage-independent K-current in rat portal veins by modifying the gating properties of the delayed rectifier. Br J Pharmacol (1993) 1.33
Some features of the spasmogenic actions of acetylcholine and histamine in guinea-pig isolated trachealis. Br J Pharmacol (1984) 1.33
Cromakalim, nicorandil and pinacidil: novel drugs which open potassium channels in smooth muscle. Gen Pharmacol (1989) 1.31
The spasmogenic action of potassium chloride in guinea-pig trachealis. Br J Pharmacol (1983) 1.31
Actions of cromakalim on ionic currents recorded from single smooth muscle cells of the rat portal vein. J Pharmacol Exp Ther (1990) 1.30
Characteristics of cromakalim-induced relaxations in the smooth muscle cells of guinea-pig mesenteric artery and vein. Br J Pharmacol (1988) 1.30
Role of gap junctions and EETs in endothelium-dependent hyperpolarization of porcine coronary artery. Br J Pharmacol (2000) 1.30
Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries. Br J Pharmacol (2004) 1.29
Differences between the effects of cromakalim and nifedipine on agonist-induced responses in rabbit aorta. Br J Pharmacol (1991) 1.29
Structure-activity relationships of K+ channel openers. Trends Pharmacol Sci (1990) 1.28
Simultaneous recording of electrical and mechanical activity from intestinal and vascular smooth muscle [proceedings]. Br J Pharmacol (1977) 1.27
Mechanical and electrical aspects of the relaxant action of aminophylline in guinea-pig isolated trachealis. Br J Pharmacol (1986) 1.27
Influence of the vascular endothelium on agonist-induced contractions and relaxations in rat aorta. Br J Pharmacol (1986) 1.26
The action of diazoxide and minoxidil sulphate on rat blood vessels: a comparison with cromakalim. Br J Pharmacol (1990) 1.26
Involvement of voltage-dependent potassium channels in the EDHF-mediated relaxation of rat hepatic artery. Br J Pharmacol (1997) 1.24
Nerve-mediated inhibition of mechanical activity in rabbit duodenum and the effects of desensitization to adenosine and several of its derivatives. Br J Pharmacol (1973) 1.21
Theophylline antagonizes some effects of purines in the intestine but not those of intramural inhibitory nerve stimulation. Br J Pharmacol (1979) 1.20
Studies on the effects of anandamide in rat hepatic artery. Br J Pharmacol (1997) 1.19
Suppression of K(+)-induced hyperpolarization by phenylephrine in rat mesenteric artery: relevance to studies of endothelium-derived hyperpolarizing factor. Br J Pharmacol (2001) 1.17
Cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy in women more than 65 years old with advanced breast cancer: the elimination of age trends in toxicity by using doses based on creatinine clearance. J Clin Oncol (1984) 1.17
The effects of isoprenaline and phenylephrine on oxygen consumption in isolated smooth muscle. Br J Pharmacol (1972) 1.14
Combination chemotherapy for metastatic breast carcinoma. Prospective comparison of multiple drug therapy with L-phenylalanine mustard. Cancer (1976) 1.14
Tumor necrosis is a prognostic predictor for early recurrence and death in lymph node-positive breast cancer: a 10-year follow-up study of 728 Eastern Cooperative Oncology Group patients. J Clin Oncol (1993) 1.14
Potassium channel modulation in rat portal vein by ATP depletion: a comparison with the effects of levcromakalim (BRL 38227). Br J Pharmacol (1992) 1.14
Potassium channel openers and vascular smooth muscle relaxation. Pharmacol Ther (1990) 1.13
Effects of isoprenaline and phenylephrine on energy-rich phosphate compounds and glucose-6-phosphate in smooth and cardiac muscle. Br J Pharmacol (1971) 1.13
Effects of P1060 and aprikalim on whole-cell currents in rat portal vein; inhibition by glibenclamide and phentolamine. Br J Pharmacol (1993) 1.10
Survivors of self-inflicted firearm injury. A liaison psychiatry perspective. Med J Aust (1994) 1.08
Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery. Br J Pharmacol (1996) 1.08
Medication regimen complexity and adherence among older adults. Image J Nurs Sch (1991) 1.07
The spontaneous electrical and mechanical activity of the longitudinal smooth muscle of the rabbit duodenum and its modification by drugs and temperature changes. J Pharm Pharmacol (1971) 1.04
Role of endothelial cell hyperpolarization in EDHF-mediated responses in the guinea-pig carotid artery. Br J Pharmacol (2000) 1.02
Inhibition of the longitudinal muscle of rabbit duodenum. Br J Pharmacol (1971) 1.02
Effects of calcium entry blockers on tension development and calcium influx in rat uterus. Br J Pharmacol (1986) 1.02
The involvement of potassium channels in the action of ciclazindol in rat portal vein. Br J Pharmacol (1992) 1.01
Induction of a glibenclamide-sensitive K-current by modification of a delayed rectifier channel in rat portal vein in insulinoma cells. Br J Pharmacol (1993) 1.01
The spasmogenic action of oxytocin in the rat uterus--comparison with other agonists. Br J Pharmacol (1986) 1.00
EDHF -- are there gaps in the pathway? J Physiol (2001) 0.98
Relaxant effects of the potassium channel activators BRL 38227 and pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by glibenclamide and BRL 31660. Pulm Pharmacol (1993) 0.95
Binding of the K+ channel opener [3H]P1075 in rat isolated aorta: relationship to functional effects of openers and blockers. Mol Pharmacol (1993) 0.95
Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein. Br J Pharmacol (1996) 0.94
An evaluation of ovarian status as a prognostic factor in disseminated cancer of the breast. Cancer (1970) 0.94
Clinical study with bleomycin. Cancer (1971) 0.94
The accumulation of adenosine in rabbit intestinal muscle. Br J Pharmacol (1974) 0.94
Comparison of the effects of several potassium-channel openers on rat bladder and rat portal vein in vitro. Br J Pharmacol (1991) 0.94
A comparison of spasmogenic and relaxant responses in aortae from C57/BL/KsJ diabetic mice with those from their non-diabetic litter mates. Pharmacology (1998) 0.94
The contribution of Rb-permeable potassium channels to the relaxant and membrane hyperpolarizing actions of cromakalim, RP49356 and diazoxide in bovine tracheal smooth muscle. Br J Pharmacol (1991) 0.94
Some effects of D600, nifedipine and sodium nitroprusside on electrical and mechanical activity in rat portal vein [proceedings]. Br J Pharmacol (1976) 0.93
5-CT stimulation of adenylyl cyclase activity in guinea-pig hippocampus: evidence for involvement of 5-HT7 and 5-HT1A receptors. Br J Pharmacol (1999) 0.93
Further investigations into the endothelium-dependent hyperpolarizing effects of bradykinin and substance P in porcine coronary artery. Br J Pharmacol (2001) 0.93
Pharmacology of the potassium channel openers. Cardiovasc Drugs Ther (1995) 0.93
Concomitant chemotherapy and split-course radiation for cure and preservation of speech and swallowing in head and neck cancer. Laryngoscope (1991) 0.93
Some effects of dipyridamole, hexobendine and lidoflazine on inhibitory processes in rabbit duodenum. Br J Pharmacol (1974) 0.91
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Central effects of urotensin-II following ICV administration in rats. Psychopharmacology (Berl) (2001) 0.89
Investigation of the effects of 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) on membrane currents in rat portal vein. Br J Pharmacol (1996) 0.89
Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity. Psychopharmacology (Berl) (2001) 0.89
Myocardial infarction survivors: age and gender differences in physical health, psychosocial state and regimen adherence. J Adv Nurs (1991) 0.89
Intermediate-conductance calcium-activated potassium channels participate in neurovascular coupling. Br J Pharmacol (2011) 0.89
Mithramycin therapy in disseminated germinal testicular cancer. JAMA (1968) 0.88