Published in J Am Soc Nephrol on June 05, 2017
The DNA-damage response in human biology and disease. Nature (2009) 17.86
The DNA damage response: making it safe to play with knives. Mol Cell (2010) 16.13
The DNA damage response: ten years after. Mol Cell (2007) 11.80
Ischemic acute renal failure: an inflammatory disease? Kidney Int (2004) 4.33
Normotensive ischemic acute renal failure. N Engl J Med (2007) 3.83
World incidence of AKI: a meta-analysis. Clin J Am Soc Nephrol (2013) 2.83
Acute kidney injury: an increasing global concern. Lancet (2013) 2.61
The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition. J Biol Chem (1998) 2.35
ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. J Biol Chem (2007) 2.31
Autophagy protects the proximal tubule from degeneration and acute ischemic injury. J Am Soc Nephrol (2011) 2.04
Regulation of PUMA-alpha by p53 in cisplatin-induced renal cell apoptosis. Oncogene (2006) 1.82
Histone H2AX phosphorylation: a marker for DNA damage. Methods Mol Biol (2012) 1.81
Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia. Am J Pathol (1992) 1.80
ATM and ATR: components of an integrated circuit. Cell Cycle (2007) 1.72
Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science (2014) 1.66
Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice. Nat Med (2016) 1.51
Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Autophagy (2012) 1.44
ELABELA: a hormone essential for heart development signals via the apelin receptor. Dev Cell (2013) 1.26
hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis. J Biol Chem (2011) 1.21
Therapeutic translation in acute kidney injury: the epithelial/endothelial axis. J Clin Invest (2014) 1.18
Accumulation of 8-oxoguanine in the cellular DNA and the alteration of the OGG1 expression during ischemia-reperfusion injury in the rat kidney. DNA Repair (Amst) (2003) 1.14
Exendin-4 and sitagliptin protect kidney from ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction. J Transl Med (2013) 1.08
Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets. J Hepatol (2011) 1.04
Challenges and advances in the treatment of AKI. J Am Soc Nephrol (2014) 1.02
Cytometric analysis of DNA damage: phosphorylation of histone H2AX as a marker of DNA double-strand breaks (DSBs). Methods Mol Biol (2009) 0.99
Curcumin inhibits neuronal and vascular degeneration in retina after ischemia and reperfusion injury. PLoS One (2011) 0.98
Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps. J Am Soc Nephrol (2015) 0.95
An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells. Cell Stem Cell (2015) 0.94
DNA hypomethylation of inflammation-associated genes in adipose tissue of female mice after multigenerational high fat diet feeding. Int J Obes (Lond) (2013) 0.93
Apelin inhibits the development of diabetic nephropathy by regulating histone acetylation in Akita mouse. J Physiol (2013) 0.92
Cilastatin attenuates cisplatin-induced proximal tubular cell damage. J Pharmacol Exp Ther (2010) 0.89
IL-22 ameliorates renal ischemia-reperfusion injury by targeting proximal tubule epithelium. J Am Soc Nephrol (2014) 0.87
Apelin alleviates diabetes-associated endoplasmic reticulum stress in the pancreas of Akita mice. Peptides (2011) 0.86
ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal via the PI3K/AKT Pathway. Cell Stem Cell (2015) 0.84
Porcine islet amyloid polypeptide fragments are refractory to amyloid formation. FEBS Lett (2010) 0.83
Structure-activity relationship studies toward the discovery of selective apelin receptor agonists. J Med Chem (2014) 0.83
Apela Regulates Fluid Homeostasis by Binding to the APJ Receptor to Activate Gi Signaling. J Biol Chem (2015) 0.81
Elabela-apelin receptor signaling pathway is functional in mammalian systems. Sci Rep (2015) 0.81
Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions. J Med Chem (2016) 0.81
Caspase-3-independent internucleosomal DNA fragmentation in ischemic acute kidney injury. Nephron Exp Nephrol (2012) 0.80
C-Terminal modifications of apelin-13 significantly change ligand binding, receptor signaling, and hypotensive action. J Med Chem (2015) 0.79
MPHOSPH1: a potential therapeutic target for hepatocellular carcinoma. Cancer Res (2014) 0.79
Overexpression of glyceraldehyde 3-phosphate dehydrogenase prevents neurovascular degeneration after retinal injury. FASEB J (2015) 0.79
Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury. Epigenetics (2015) 0.79
Effect of adriamycin combined with whole body hyperthermia on tumor and normal tissues. Cancer Res (1991) 0.78
Renal 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase Is an Important Determinant of AKI Severity after Ischemia-Reperfusion. J Am Soc Nephrol (2015) 0.77
Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells. Toxicol Appl Pharmacol (2015) 0.76
Protective effects of the exopolysaccharide Lasiodiplodan against DNA damage and inflammation induced by doxorubicin in rats: Cytogenetic and gene expression assays. Toxicology (2016) 0.76
CD103+ Dendritic Cells Elicit CD8+ T Cell Responses to Accelerate Kidney Injury in Adriamycin Nephropathy. J Am Soc Nephrol (2015) 0.76
Restoration of Opa1-long isoform inhibits retinal injury-induced neurodegeneration. J Mol Med (Berl) (2015) 0.76
Apelin protects against acute renal injury by inhibiting TGF-β1. Biochim Biophys Acta (2015) 0.76
Histone HIST1H1C/H1.2 regulates autophagy in the development of diabetic retinopathy. Autophagy (2017) 0.76