Increased humoral immunity by DNA vaccination using an α-tocopherol-based adjuvant.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28613978)

Published in Hum Vaccin Immunother on June 14, 2017

Authors

Ingrid Karlsson1, Marie Borggren1, Jens Nielsen1, Dennis Christensen2, Jim Williams3, Anders Fomsgaard1,4

Author Affiliations

1: a Virus Research and Development Laboratory, Department of Virus and Microbiological Special Diagnostics , Statens Serum Institut , Copenhagen , Denmark.
2: b Department of Infectious Disease Immunology, Vaccine Adjuvant Research , Statens Serum Institut , Copenhagen , Denmark.
3: c Nature Technology Corporation , Lincoln , NE , USA.
4: d Infectious Disease Research Unit, Clinical Institute , University of Southern Denmark , Odense , Denmark.

Articles cited by this

Heterologous protection against influenza by injection of DNA encoding a viral protein. Science (1993) 10.14

Modes of action of Freund's adjuvants in experimental models of autoimmune diseases. J Leukoc Biol (2001) 2.61

Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies. J Immunol (2013) 1.95

Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques. Vaccine (2007) 1.88

Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity. Vaccine (2011) 1.77

Overview of STEP and Phambili trial results: two phase IIb test-of-concept studies investigating the efficacy of MRK adenovirus type 5 gag/pol/nef subtype B HIV vaccine. Curr Opin HIV AIDS (2010) 1.63

Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF. J Immunol (2002) 1.58

Current progress of DNA vaccine studies in humans. Expert Rev Vaccines (2008) 1.42

Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization. J Virol (1997) 1.38

The mechanism of action of MF59 - an innately attractive adjuvant formulation. Vaccine (2012) 1.33

Traditional and new influenza vaccines. Clin Microbiol Rev (2013) 1.22

The relative immunogenicity of DNA vaccines delivered by the intramuscular needle injection, electroporation and gene gun methods. Vaccine (2008) 1.20

Synthetic DNA vaccines: improved vaccine potency by electroporation and co-delivered genetic adjuvants. Front Immunol (2013) 1.19

One dose of a porcine circovirus 2 subunit vaccine induces humoral and cell-mediated immunity and protects against porcine circovirus-associated disease under field conditions. Vet Microbiol (2010) 1.03

Enhancement of DNA vaccine potency using conventional aluminum adjuvants. Vaccine (1999) 0.98

Topical delivery of imiquimod to a mouse model as a novel adjuvant for human immunodeficiency virus (HIV) DNA. Vaccine (2004) 0.97

Enhancement of the humoral immune response by vitamin E. Int Arch Allergy Appl Immunol (1973) 0.93

Construction, biological activity, and immunogenicity of synthetic envelope DNA vaccines based on a primary, CCR5-tropic, early HIV type 1 isolate (BX08) with human codons. AIDS Res Hum Retroviruses (2000) 0.89

Treatment of tumors with vitamin E suppresses myeloid derived suppressor cells and enhances CD8+ T cell-mediated antitumor effects. PLoS One (2014) 0.88

The next generation recombinant human cytomegalovirus vaccine candidates-beyond gB. Vaccine (2012) 0.88

Vector Design for Improved DNA Vaccine Efficacy, Safety and Production. Vaccines (Basel) (2013) 0.88

Resiquimod is a modest adjuvant for HIV-1 gag-based genetic immunization in a mouse model. Vaccine (2004) 0.87

Therapeutic immunization of HIV-infected chimpanzees using HIV-1 plasmid antigens and interleukin-12 expressing plasmids. AIDS (2000) 0.87

A polyvalent influenza A DNA vaccine induces heterologous immunity and protects pigs against pandemic A(H1N1)pdm09 virus infection. Vaccine (2013) 0.85

Optimal Use of Vaccines for Control of Influenza A Virus in Swine. Vaccines (Basel) (2015) 0.83

Pentamers not found in the universal proteome can enhance antigen specific immune responses and adjuvant vaccines. PLoS One (2012) 0.83

Vector optimization and needle-free intradermal application of a broadly protective polyvalent influenza A DNA vaccine for pigs and humans. Hum Vaccin Immunother (2015) 0.83

HIV-DNA Given with or without Intradermal Electroporation Is Safe and Highly Immunogenic in Healthy Swedish HIV-1 DNA/MVA Vaccinees: A Phase I Randomized Trial. PLoS One (2015) 0.82

DNA vaccines against influenza. Acta Biochim Pol (2014) 0.81

Progress on adenovirus-vectored universal influenza vaccines. Hum Vaccin Immunother (2015) 0.80

Molecular mechanisms for enhanced DNA vaccine immunogenicity. Expert Rev Vaccines (2015) 0.79

Viral vector-based influenza vaccines. Hum Vaccin Immunother (2016) 0.79

Evaluation of the immune response induced by intradermal vaccination by using a needle-less system in comparison with the intramuscular route in conventional pigs. Res Vet Sci (2010) 0.78

Supplementation with natural forms of vitamin E augments antigen-specific TH1-type immune response to tetanus toxoid. Biomed Res Int (2013) 0.78

Combinations of various CpG motifs cloned into plasmid backbone modulate and enhance protective immunity of viral replicon DNA anthrax vaccines. Med Microbiol Immunol (2014) 0.77

Intradermal application of Aujeszky's disease virus strain Begonia with tocopherol-based adjuvant and a novel design injection device. Acta Vet Hung (1994) 0.77

Influenza nucleoprotein DNA vaccination by a skin targeted, dry coated, densely packed microprojection array (Nanopatch) induces potent antibody and CD8(+) T cell responses. J Control Release (2016) 0.76

A polyvalent influenza DNA vaccine applied by needle-free intradermal delivery induces cross-reactive humoral and cellular immune responses in pigs. Vaccine (2016) 0.76

Oral vaccination with a liposome-encapsulated influenza DNA vaccine protects mice against respiratory challenge infection. J Med Virol (2013) 0.76