PubRank

T M McIntyre

Author PubWeight™ 190.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rapid neutrophil adhesion to activated endothelium mediated by GMP-140. Nature 1990 5.17
2 Platelet-activating factor and related lipid mediators. Annu Rev Biochem 2000 3.44
3 Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures. J Clin Invest 1995 3.14
4 Endothelial cell interactions with granulocytes: tethering and signaling molecules. Immunol Today 1992 3.06
5 Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils. J Cell Biol 1991 3.05
6 Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. J Clin Invest 2001 3.01
7 Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Nature 1995 2.79
8 Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesis. J Cell Biol 2001 2.75
9 Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J Biol Chem 1993 2.61
10 Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils. J Cell Biol 1991 2.59
11 Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. J Clin Invest 1985 2.58
12 Activated platelets signal chemokine synthesis by human monocytes. J Clin Invest 1996 2.51
13 Induction of IgG3 secretion by interferon gamma: a model for T cell-independent class switching in response to T cell-independent type 2 antigens. J Exp Med 1992 2.47
14 Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin. Proc Natl Acad Sci U S A 1984 2.28
15 Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase. J Clin Invest 1996 2.21
16 Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta. Nature 1998 2.20
17 Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils. Proc Natl Acad Sci U S A 1986 2.18
18 Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate. J Clin Invest 1985 2.16
19 Platelet-activating factor. J Biol Chem 1990 2.13
20 Neutrophil adherence to human endothelium in vitro occurs by CDw18 (Mo1, MAC-1/LFA-1/GP 150,95) glycoprotein-dependent and -independent mechanisms. J Clin Invest 1988 2.12
21 Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation. J Clin Invest 1995 2.06
22 Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region. J Biol Chem 2000 2.05
23 Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets. Proc Natl Acad Sci U S A 1998 1.97
24 Human plasma platelet-activating factor acetylhydrolase. Association with lipoprotein particles and role in the degradation of platelet-activating factor. J Biol Chem 1987 1.93
25 Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect. Proc Natl Acad Sci U S A 1996 1.88
26 Inflammatory roles of P-selectin. J Clin Invest 1993 1.87
27 Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J Clin Invest 1997 1.87
28 Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists. J Biol Chem 2001 1.86
29 Intracellular unesterified arachidonic acid signals apoptosis. Proc Natl Acad Sci U S A 2000 1.85
30 Endothelial cell-associated platelet-activating factor: a novel mechanism for signaling intercellular adhesion. J Cell Biol 1990 1.84
31 Human plasma platelet-activating factor acetylhydrolase. Oxidatively fragmented phospholipids as substrates. J Biol Chem 1991 1.71
32 Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein. J Clin Invest 1995 1.66
33 The leukocyte integrins. J Biol Chem 2000 1.65
34 Human plasma platelet-activating factor acetylhydrolase. Purification and properties. J Biol Chem 1987 1.55
35 Platelet-activating factor acetylhydrolases. J Biol Chem 1997 1.51
36 Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion. J Clin Invest 1988 1.51
37 Activation of human neutrophil phospholipase D by three separable mechanisms. FASEB J 1990 1.50
38 An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasma. J Biol Chem 1989 1.48
39 Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades. J Biol Chem 1996 1.47
40 Neutrophil activating factor (NAF) induces polymorphonuclear leukocyte adherence to endothelial cells and to subendothelial matrix proteins. Biochem Biophys Res Commun 1989 1.46
41 Molecular basis of the interaction between plasma platelet-activating factor acetylhydrolase and low density lipoprotein. J Biol Chem 1999 1.46
42 Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells. J Clin Invest 1995 1.44
43 Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad. J Biol Chem 1995 1.44
44 Platelet-activating factor acetylhydrolase increases during macrophage differentiation. A novel mechanism that regulates accumulation of platelet-activating factor. J Biol Chem 1989 1.42
45 Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates. J Biol Chem 1996 1.39
46 Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells. J Biol Chem 1999 1.35
47 Somatic cell cloning in polyester stacks. Proc Natl Acad Sci U S A 1982 1.31
48 Molecular cloning and characterization of a novel human diacylglycerol kinase zeta. J Biol Chem 1996 1.31
49 CD11b/CD18 integrin and a beta-glucan receptor act in concert to induce the synthesis of platelet-activating factor by monocytes. J Immunol 1994 1.30
50 Borrelia burgdorferi outer membrane protein A induces nuclear translocation of nuclear factor-kappa B and inflammatory activation in human endothelial cells. J Immunol 1996 1.30
51 Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor. J Biol Chem 1991 1.29
52 Thrombin stimulates neutrophil adherence by an endothelial cell-dependent mechanism: characterization of the response and relationship to platelet-activating factor synthesis. Ann N Y Acad Sci 1986 1.28
53 Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha. J Clin Invest 1997 1.28
54 Adhesion and signaling in vascular cell--cell interactions. J Clin Invest 1996 1.27
55 Production of platelet-activating factor by stimulated human polymorphonuclear leukocytes. Correlation of synthesis with release, functional events, and leukotriene B4 metabolism. J Immunol 1987 1.25
56 Inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines. J Biol Chem 1999 1.25
57 Platelet-activating factor: a phospholipid autacoid with diverse actions. J Lipid Res 1993 1.25
58 Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfaces. J Clin Invest 1995 1.22
59 Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets. J Cell Biol 1999 1.21
60 Mutants of Escherichia coli defective in membrane phospholipid synthesis. Effects of cessation and reinitiation of phospholipid synthesis on macromolecular synthesis and phospholipid turnover. J Biol Chem 1977 1.20
61 Human macrophages secret platelet-activating factor acetylhydrolase. J Biol Chem 1990 1.20
62 Expression of plasma platelet-activating factor acetylhydrolase is transcriptionally regulated by mediators of inflammation. J Biol Chem 1998 1.19
63 Platelet-activating factor acetylhydrolase from human plasma. Methods Enzymol 1990 1.17
64 The regulation of platelet-activating factor production in endothelial cells. The role of calcium and protein kinase C. J Biol Chem 1989 1.16
65 Alpha toxin from Clostridium perfringens induces proinflammatory changes in endothelial cells. J Clin Invest 1997 1.16
66 Oncostatin M is a proinflammatory mediator. In vivo effects correlate with endothelial cell expression of inflammatory cytokines and adhesion molecules. J Clin Invest 1997 1.12
67 The platelet-activating factor acetylhydrolase from human plasma prevents oxidative modification of low-density lipoprotein. Trans Assoc Am Physicians 1992 1.12
68 Cloning, expression, and chromosomal localization of human long-chain fatty acid-CoA ligase 4 (FACL4). Genomics 1998 1.12
69 Bioactive phospholipid oxidation products. Free Radic Biol Med 2000 1.11
70 Platelet-activating factor: a mediator for clinicians. J Intern Med 1995 1.11
71 Novel leukocyte agonists are released by endothelial cells exposed to peroxide. J Biol Chem 1992 1.09
72 Mammalian platelet-activating factor acetylhydrolases. Biochim Biophys Acta 1996 1.09
73 Differential regulation of matrix metalloproteinase-9 by monocytes adherent to collagen and platelets. Circ Res 2001 1.07
74 Lipoproteins alter the catalytic behavior of the platelet-activating factor acetylhydrolase in human plasma. Proc Natl Acad Sci U S A 1989 1.06
75 Inflammatory agonists induce cyclooxygenase type 2 expression by human neutrophils. J Immunol 1998 1.05
76 Shear stress activates cytosolic phospholipase A2 (cPLA2) and MAP kinase in human endothelial cells. Biochem Biophys Res Commun 1996 1.05
77 Endothelial activation in ARDS. Chest 1999 1.04
78 The cloning and characterization of a novel human diacylglycerol kinase, DGKiota. J Biol Chem 1998 1.03
79 A novel syndrome of variant leukocyte adhesion deficiency involving defects in adhesion mediated by beta1 and beta2 integrins. Blood 2001 1.02
80 Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma. J Clin Invest 1999 1.02
81 Mutants of Escherichia coli defective in membrane phospholipid synthesis. Effect of cessation of net phospholipid synthesis on cytoplasmic and outer membranes. J Biol Chem 1975 1.02
82 Synthesis and release of platelet-activating factor by stimulated human mononuclear phagocytes. J Immunol 1988 1.02
83 P-selectin regulates platelet-activating factor synthesis and phagocytosis by monocytes. J Immunol 1995 1.01
84 The platelet-activating factor acetylhydrolase from human erythrocytes. Purification and properties. J Biol Chem 1993 1.01
85 IL-10 selectively regulates murine Ig isotype switching. Int Immunol 1996 1.01
86 Fluid flow activates a regulator of translation, p70/p85 S6 kinase, in human endothelial cells. Am J Physiol Heart Circ Physiol 2000 1.01
87 Production of platelet-activating factor by human vascular endothelial cells: evidence for a requirement for specific agonists and modulation by prostacyclin. Circulation 1985 1.00
88 Oxidized LDL contains inflammatory PAF-like phospholipids. Trends Cardiovasc Med 2001 0.99
89 Expression of fatty acid-CoA ligase 4 during development and in brain. FEBS Lett 2000 0.99
90 Human endothelial cells synthesize ENA-78: relationship to IL-8 and to signaling of PMN adhesion. Am J Respir Cell Mol Biol 1997 0.98
91 Comparison of the hydrolytic and transfer activities of rat renal gamma-glutamyltranspeptidase. J Biol Chem 1979 0.95
92 Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids. J Lipid Res 2001 0.94
93 Alternative splicing of the human diacylglycerol kinase zeta gene in muscle. Proc Natl Acad Sci U S A 1997 0.94
94 The necrotic venom of the brown recluse spider induces dysregulated endothelial cell-dependent neutrophil activation. Differential induction of GM-CSF, IL-8, and E-selectin expression. J Clin Invest 1994 0.94
95 Escherichia coli Braun lipoprotein induces a lipopolysaccharide-like endotoxic response from primary human endothelial cells. J Immunol 2001 0.93
96 Escherichia coli mutants defective in membrane phospholipid synthesis: binding and metabolism of 1-oleoylglycerol 3-phosphate by a plsB deep rough mutant. J Bacteriol 1978 0.92
97 Lipid metabolism and signal transduction in endothelial cells. Prog Lipid Res 1990 0.91
98 Production of platelet-activating factor by endothelial cells. Semin Thromb Hemost 1987 0.90
99 Endothelial cells for studies of platelet-activating factor and arachidonate metabolites. Methods Enzymol 1990 0.90
100 Proliferation-dependent changes in release of arachidonic acid from endothelial cells. J Clin Invest 1994 0.89
101 Induction of cyclooxygenase-2 by human monocytes exposed to group B streptococci. J Leukoc Biol 2000 0.89
102 The interorgan metabolism of glutathione. Int J Biochem 1980 0.89
103 Phospholipid remodeling in human neutrophils. Parallel activation of a deacylation/reacylation cycle and platelet-activating factor synthesis. J Biol Chem 1989 0.89
104 Juxtacrine intercellular signaling: another way to do it. Am J Respir Cell Mol Biol 1993 0.89
105 Uteroplacental insufficiency decreases p53 serine-15 phosphorylation in term IUGR rat lungs. Am J Physiol Regul Integr Comp Physiol 2007 0.88
106 Liver cells secrete the plasma form of platelet-activating factor acetylhydrolase. J Biol Chem 1991 0.87
107 Oxidatively fragmented phospholipids as inflammatory mediators: the dark side of polyunsaturated lipids. J Nutr 1995 0.87
108 Endothelium from diverse vascular sources synthesizes platelet-activating factor. Arteriosclerosis 1988 0.87
109 Growth-dependent changes in arachidonic acid release from endothelial cells are mediated by protein kinase C and changes in diacylglycerol. J Biol Chem 1993 0.86
110 Platelet-activating factor acetylhydrolase activity in human tissues and blood cells. Lipids 1991 0.86
111 The interaction of leukocytes with platelets in blood coagulation. Curr Opin Hematol 1995 0.86
112 Regulation of platelet-activating factor (PAF) synthesis and PAF-mediated neutrophil adhesion to endothelial cells activated by thrombin. Semin Thromb Hemost 1992 0.86
113 Two of the usual suspects, platelet-activating factor and its receptor, implicated in acute lung injury. J Clin Invest 1999 0.85
114 Synthesis of platelet-activating factor by endothelial cells. The role of G proteins. J Biol Chem 1990 0.85
115 Platelet-activating factor acetylhydrolase in human erythrocytes. Methods Enzymol 1991 0.84
116 Human macrophages secrete platelet-activating factor acetylhydrolase. A mechanism for resolution of pulmonary inflammation. Chest 1991 0.83
117 Coengagement of ICAM-3 and Fc receptors induces chemokine secretion and spreading by myeloid leukocytes. J Immunol 1998 0.83
118 Juxtacrine interactions of endothelial cells with leukocytes: tethering and signaling molecules. Behring Inst Mitt 1993 0.83
119 Production of platelet-activating factor, a biologically active lipid, by vascular endothelial cells. Am Rev Respir Dis 1987 0.83
120 Events at the vascular wall: the molecular basis of inflammation. J Investig Med 2001 0.82
121 Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021. Int J Radiat Oncol Biol Phys 1995 0.82
122 Brief review: molecular mechanisms of neutrophil binding to endothelium involving platelet-activating factor and cytokines. J Lipid Mediat 1990 0.82
123 Brush border membrane hydrolysis of S-benzyl-cysteine-p-nitroanilide, and activity of aminopeptidase M. Biochem Biophys Res Commun 1980 0.82
124 The role of platelet-activating factor in endothelial cells. Thromb Haemost 1990 0.81
125 Endothelial cells reestablish functional integrity after reversible permeabilization. Arterioscler Thromb 1991 0.80
126 Inflammation as an early component of atherosclerosis and vascular damage--a role for P-selectin and platelet-activating factor. Jpn Circ J 1996 0.79
127 Human endothelial cells regulate polymorphonuclear leukocyte degranulation. FASEB J 1998 0.79
128 The cloning and developmental regulation of murine diacylglycerol kinase zeta. FEBS Lett 1998 0.79
129 Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver. J Lipid Res 2001 0.79
130 Hirudin-based peptides block the inflammatory effects of thrombin on endothelial cells. J Biol Chem 1990 0.79
131 Functional and structural features of plasma platelet-activating factor acetylhydrolase. Adv Exp Med Biol 1996 0.79
132 Adhesion and signaling in vascular cell-cell interactions. J Clin Invest 1997 0.78
133 Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions. J Thromb Haemost 2014 0.78
134 Characterization of the platelet-activating factor acetylhydrolase from human plasma by heterologous expression in Xenopus laevis oocytes. Proc Natl Acad Sci U S A 1994 0.78
135 Direct quantitative in situ hybridization studies of Ig VH utilization. A comparison between unstimulated B cells from autoimmune and normal mice. J Immunol 1989 0.78
136 Bacterial lipopolysaccharide induces endothelial cells to synthesize a degranulating factor for neutrophils. FASEB J 1998 0.78
137 Relative amounts of 1-O-alkyl- and 1-acyl-2-acetyl-sn-glycero-3-phosphocholine in stimulated endothelial cells. Prostaglandins 1992 0.78
138 Engagement of ICAM-3 activates polymorphonuclear leukocytes: aggregation without degranulation or beta 2 integrin recruitment. J Immunol 1998 0.78
139 Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes. Am J Respir Cell Mol Biol 1991 0.77
140 Activation of the acetyl-coenzyme A:lysoplatelet-activating factor acetyltransferase regulates platelet-activating factor synthesis in human endothelial cells. J Biol Chem 1992 0.77
141 Platelet-activating factor: antagonists, terminators, molecular mimics, and microbial opportunism. J Intern Med 1996 0.77
142 Characterization of human UMP-CMP kinase enzymatic activity and 5' untranslated region. Life Sci 2001 0.77
143 Platelet-activating factor mediates procoagulant activity on the surface of endothelial cells by promoting leukocyte adhesion. Semin Cell Biol 1995 0.77
144 Inflammation in the vascular wall as an early event in atherosclerosis. Diabetologia 1997 0.76
145 The regulation of synthesis of platelet-activating factor by endothelial cells. Chest 1988 0.75
146 Cardiovascular effects of platelet-activating factor. Trends Cardiovasc Med 1991 0.75