Salmonella typhimurium A1-R targeting of a chemotherapy resistant BRAF-V600E melanoma in a patient-derived orthotopic xenograft (PDOX) model is enhanced in combination with either vemurafenib-temozlomide.

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Published in Cell Cycle on June 16, 2017

Authors

Kei Kawaguchi1,2,3, Kentaro Igarashi1,2, Takashi Murakami1,2, Tasuku Kiyuna1,2, Ming Zhao1, Yong Zhang1, Scott D Nelson4, Tara A Russell5, Sarah M Dry4, Arun S Singh6, B Chmielowski7, Yunfeng Li4, Michiaki Unno3, Fritz C Eilber8, Robert M Hoffman1,2

Author Affiliations

1: a AntiCancer, Inc. , San Diego , CA , USA.
2: b Department of Surgery , University of California , San Diego , CA , USA.
3: c Department of Surgery, Graduate School of Medicine , Tohoku University , Sendai , Japan.
4: d Department of Pathology , University of California , Los Angeles , CA , USA.
5: e Division of Surgical Oncology , University of California , Los Angeles , CA , USA.
6: f Division of Hematology-Oncology , University of California , Los Angeles , CA , USA.
7: Division of Hematology - Medical Oncology, Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA, 90049, U.S.A.. bchmielowski@mednet.ucla.edu.
8: f Div. of Surgical Oncology, University of California , Los Angeles , CA.

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