Published in PLoS One on July 03, 2017
Aging and motivated cognition: the positivity effect in attention and memory. Trends Cogn Sci (2005) 5.85
Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation. Cell (1999) 4.98
Fear conditioning induces associative long-term potentiation in the amygdala. Nature (1997) 4.80
The emerging field of lipidomics. Nat Rev Drug Discov (2005) 4.69
Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics. J Lipid Res (2008) 3.96
Ageing and neuronal vulnerability. Nat Rev Neurosci (2006) 3.36
The aging brain. Annu Rev Pathol (2008) 3.28
Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis. J Neurochem (2002) 2.45
Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified? Alzheimers Dement (2005) 2.09
Engineering a memory with LTD and LTP. Nature (2014) 2.03
A neuroscientist's guide to lipidomics. Nat Rev Neurosci (2007) 1.87
The role of amygdala glutamate receptors in fear learning, fear-potentiated startle, and extinction. Pharmacol Biochem Behav (2002) 1.87
Shorthand notation for lipid structures derived from mass spectrometry. J Lipid Res (2013) 1.80
Comparative lipidomic analysis of mouse and human brain with Alzheimer disease. J Biol Chem (2011) 1.51
Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. J Neurosci (2010) 1.49
Molecular recognition of a single sphingolipid species by a protein's transmembrane domain. Nature (2012) 1.42
Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem (2000) 1.38
Alpha-synuclein, lipids and Parkinson's disease. Prog Lipid Res (2010) 1.24
Phosphatidylserine is a critical modulator for Akt activation. J Cell Biol (2011) 1.20
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry. J Lipid Res (2011) 1.19
Phosphatidyl-L-serine is necessary for protein kinase C's high-affinity interaction with diacylglycerol-containing membranes. Biochemistry (1994) 1.16
Functional analysis of a phosphatidic acid binding domain in human Raf-1 kinase: mutations in the phosphatidate binding domain lead to tail and trunk abnormalities in developing zebrafish embryos. J Biol Chem (2003) 1.14
Lipidomics: analysis of the lipid composition of cells and subcellular organelles by electrospray ionization mass spectrometry. Annu Rev Biochem (2014) 1.07
Phospholipase D in brain function and Alzheimer's disease. Biochim Biophys Acta (2010) 1.06
Ceramide as a second messenger: sticky solutions to sticky problems. Trends Cell Biol (2000) 1.02
Age-associated changes in central nervous system glycerolipid composition and metabolism. Neurochem Res (2002) 1.02
A recollection of mTOR signaling in learning and memory. Learn Mem (2013) 1.01
Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with alpha-synuclein genotype. J Neurochem (2009) 1.01
Age-related changes in ethanolamine glycerophospholipid fatty acid levels in rat frontal cortex and hippocampus. Neurobiol Aging (2000) 1.00
Brain membrane lipids in major depression and anxiety disorders. Biochim Biophys Acta (2014) 1.00
Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer's disease. Lipids Health Dis (2013) 0.97
Lipid pathway alterations in Parkinson's disease primary visual cortex. PLoS One (2011) 0.96
Phospholipids and insulin resistance in psychosis: a lipidomics study of twin pairs discordant for schizophrenia. Genome Med (2012) 0.91
Role of phosphatidylcholine during neuronal differentiation. IUBMB Life (2011) 0.90
Phosphatidylserine in the brain: metabolism and function. Prog Lipid Res (2014) 0.85
The Affective Neuroscience of Aging. Annu Rev Psychol (2015) 0.84
Aging impairs amygdala-hippocampus interactions involved in hippocampal LTP. Neurobiol Aging (2002) 0.84
Increase in sphingolipid catabolic enzyme activity during aging. Acta Pharmacol Sin (2009) 0.84
Aging induces tissue-specific changes in cholesterol metabolism in rat brain and liver. Lipids (2013) 0.84
Organization and evolution of brain lipidome revealed by large-scale analysis of human, chimpanzee, macaque, and mouse tissues. Neuron (2015) 0.83
Lipidomics of human brain aging and Alzheimer's disease pathology. Int Rev Neurobiol (2015) 0.82
Regional lipid composition in the rat brain. Mol Chem Neuropathol (1993) 0.82
Phosphatidylserine increases the affinity of the AMPA/quisqualate receptor in rat brain membranes. Behav Neural Biol (1991) 0.82
Measuring brain lipids. Biochim Biophys Acta (2015) 0.81
Comparative Lipidomics of Caenorhabditis elegans Metabolic Disease Models by SWATH Non-Targeted Tandem Mass Spectrometry. Metabolites (2015) 0.81
Age increases anxiety and reactivity of the fear/anxiety circuit in Lewis rats. Behav Brain Res (2011) 0.80
Changes in the ceramide composition of rat forebrain gangliosides with age. J Neurochem (1990) 0.80
Dopamine-induced plasticity, phospholipase D (PLD) activity and cocaine-cue behavior depend on PLD-linked metabotropic glutamate receptors in amygdala. PLoS One (2011) 0.79
Protein kinase D: a new player among the signaling proteins that regulate functions in the nervous system. Neurosci Bull (2014) 0.79
Depletion of the lipid raft constituents, sphingomyelin and ganglioside, decreases serotonin binding at human 5-HT7(a) receptors in HeLa cells. Acta Physiol (Oxf) (2007) 0.78
The impact of chronic stress on the rat brain lipidome. Mol Psychiatry (2015) 0.77
Lipidomics reveals dysfunctional glycosynapses in schizophrenia and the G72/G30 transgenic mouse. Schizophr Res (2014) 0.77
MR volumetric study of piriform-cortical amygdala and orbitofrontal cortices: the aging effect. PLoS One (2013) 0.77
Phosphatidic acid and diacylglycerol generation is regulated by insulin in cerebral cortex synaptosomes from adult and aged rats. J Neurosci Res (2005) 0.77
Ceramide and Related-Sphingolipid Levels Are Not Altered in Disease-Associated Brain Regions of APP and APP/PS1 Mouse Models of Alzheimer's Disease: Relationship with the Lack of Neurodegeneration? Int J Alzheimers Dis (2010) 0.76
Lipid raft integrity affects GABAA receptor, but not NMDA receptor modulation by psychopharmacological compounds. Int J Neuropsychopharmacol (2012) 0.76
Fear potentiated startle increases phospholipase D (PLD) expression/activity and PLD-linked metabotropic glutamate receptor mediated post-tetanic potentiation in rat amygdala. Neurobiol Learn Mem (2015) 0.76
Serine phospholipids and aging brain. Prog Clin Biol Res (1985) 0.76
Lipidomics by ultrahigh performance liquid chromatography-high resolution mass spectrometry and its application to complex biological samples. J Chromatogr B Analyt Technol Biomed Life Sci (2017) 0.76
Amygdala-Hippocampal Phospholipase D (PLD) Signaling As Novel Mechanism of Cocaine-Environment Maladaptive Conditioned Responses. Int J Neuropsychopharmacol (2016) 0.75