Published in Philos Trans R Soc Lond B Biol Sci on December 17, 1985
Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells. Gastroenterology (2008) 2.31
Medicinal applications of fullerenes. Int J Nanomedicine (2007) 1.53
Experimental liver fibrosis research: update on animal models, legal issues and translational aspects. Fibrogenesis Tissue Repair (2013) 1.27
Free radicals and tissue injury: fact and fiction. Br J Cancer Suppl (1987) 0.92
S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice. Eur J Nutr (2011) 0.86
Studies on lipid peroxidation in normal and tumour tissues. The Yoshida rat liver tumour. Biochem J (1988) 0.79
Dietary olive oil prevents carbon tetrachloride-induced hepatic fibrosis in mice. J Gastroenterol (2009) 0.77
Activated ErbB3 Translocates to the Nucleus via Clathrin-independent Endocytosis, Which Is Associated with Proliferating Cells. J Biol Chem (2015) 0.76
Haloalkane induced hepatic insult in murine model: amelioration by Oleander through antioxidant and anti-inflammatory activities, an in vitro and in vivo study. BMC Complement Altern Med (2016) 0.75
Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol (1990) 6.05
Free-radical mechanisms in tissue injury. Biochem J (1984) 4.70
Necrogenic action of carbon tetrachloride in the rat: a speculative mechanism based on activation. Nature (1966) 3.27
Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E. Am J Clin Nutr (1998) 2.98
Direct observation of a free radical interaction between vitamin E and vitamin C. Nature (1979) 2.91
beta-Carotene: an unusual type of lipid antioxidant. Science (1984) 2.76
The relative contributions of vitamin E, urate, ascorbate and proteins to the total peroxyl radical-trapping antioxidant activity of human blood plasma. Biochim Biophys Acta (1987) 2.68
The stimulatory effects of carbon tetrachloride and other halogenoalkanes on peroxidative reactions in rat liver fractions in vitro. General features of the systems used. Biochem J (1971) 2.65
An introduction to free radical biochemistry. Br Med Bull (1993) 2.30
Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes. Biochem J (1982) 2.11
An assay procedure for nicotinamide-adenine dinucleotides in rat liver and other tissues. Arch Int Physiol Biochim (1964) 2.02
Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes? Arch Biochem Biophys (1983) 1.99
Changes in liver nucleotide concentrations in experimental liver injury. 1. Carbon tetrachloride poisoning. Biochem J (1964) 1.74
Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy. Circ Res (1987) 1.74
Solvent effects on the rates and mechanisms of reaction of phenols with free radicals. Acc Chem Res (2007) 1.73
Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspensions. Biochem J (1985) 1.58
Changes in lysosomal enzymes in acute experimental liver injury. Biochem J (1965) 1.57
Overview of methods used for detecting lipid peroxidation. Methods Enzymol (1984) 1.54
Isomerization of triphenylmethoxyl: the Wieland free-radical rearrangement revisited a century later. Angew Chem Int Ed Engl (2010) 1.50
The effects of carbon tetrachloride on rat liver microsomes during the first hour of poisoning in vivo, and the modifying actions of promethazine. Biochem J (1969) 1.49
Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant. Biochem J (1992) 1.43
Quantitative measurement of the total, peroxyl radical-trapping antioxidant capability of human blood plasma by controlled peroxidation. The important contribution made by plasma proteins. FEBS Lett (1985) 1.43
Studies on human uterine cervix and rat uterus using S-, X- and Q-band electron-spin-resonance spectroscopy. Biochem J (1984) 1.38
Electron spin resonance studies on normal human uterus and cervix and on benign and malignant uterine tumors. Cancer Res (1981) 1.36
Impaired ability of patients with familial isolated vitamin E deficiency to incorporate alpha-tocopherol into lipoproteins secreted by the liver. J Clin Invest (1990) 1.31
Vitamin E as an in vitro and in vivo antioxidant. Ann N Y Acad Sci (1989) 1.29
The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Inhibitory effects of free-radical scavengers and other agents. Biochem J (1971) 1.28
Reactions of the carbon tetrachloride-related peroxy free radical (CC13O.2) with amino acids: pulse radiolysis evidence. Life Sci (1978) 1.28
Free radicals and singlet oxygen scavengers: reaction of a peroxy-radical with beta-carotene, diphenyl furan and 1,4-diazobicyclo (2,2,2)-octane. Biochem Biophys Res Commun (1981) 1.27
Vitamin E as an antioxidant in vitro and in vivo. Ciba Found Symp (1983) 1.24
First proof that vitamin E is major lipid-soluble, chain-breaking antioxidant in human blood plasma. Lancet (1982) 1.23
Discrimination between forms of vitamin E by humans with and without genetic abnormalities of lipoprotein metabolism. J Lipid Res (1992) 1.22
Detection of malonaldehyde by high-performance liquid chromatography. Methods Enzymol (1984) 1.21
Photosensitization and lysosomal damage. Nature (1966) 1.18
Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study. Mov Disord (1994) 1.18
Antioxidant and co-antioxidant activity of vitamin C. The effect of vitamin C, either alone or in the presence of vitamin E or a water-soluble vitamin E analogue, upon the peroxidation of aqueous multilamellar phospholipid liposomes. Biochim Biophys Acta (1985) 1.16
Spin-trapping studies on the free-radical products formed by metabolic activation of carbon tetrachloride in rat liver microsomal fractions isolated hepatocytes and in vivo in the rat. Biochem J (1982) 1.16
Pathogenesis of retrolental fibroplasia. Lancet (1969) 1.13
Abnormal solvent effects on hydrogen atom abstraction. 2. Resolution of the curcumin antioxidant controversy. The role of sequential proton loss electron transfer. J Org Chem (2004) 1.10
Cytochrome P-450 distribution in rat liver and the effect of sodium phenobarbitone administration. Chem Biol Interact (1978) 1.10
The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Interaction sites in the endoplasmic reticulum. Biochem J (1971) 1.08
A mild, rapid, and efficient method of lipid extraction for use in determining vitamin E/lipid ratios. Lipids (1985) 1.08
Measuring free radical reactions in vivo. Br Med Bull (1993) 1.06
Reaction of the trichloromethyl and halothane-derived peroxy radicals with unsaturated fatty acids: a pulse radiolysis study. Chem Biol Interact (1983) 1.04
Critical re-evaluation of the O-H bond dissociation enthalpy in phenol. J Phys Chem A (2005) 1.03
The antioxidant efficiency of vitamin C is concentration-dependent. Biochim Biophys Acta (1986) 1.03
Cytochrome P450 hydroxylation of hydrocarbons: variation in the rate of oxygen rebound using cyclopropyl radical clocks including two new ultrafast probes. Biochemistry (1993) 1.01
RRR- and SRR-alpha-tocopherols are secreted without discrimination in human chylomicrons, but RRR-alpha-tocopherol is preferentially secreted in very low density lipoproteins. J Lipid Res (1990) 1.00
Reaction of phenols with the 2,2-diphenyl-1-picrylhydrazyl radical. Kinetics and DFT calculations applied to determine ArO-H bond dissociation enthalpies and reaction mechanism. J Org Chem (2008) 0.99
Abnormal solvent effects on hydrogen atom abstractions. 1. The reactions of phenols with 2,2-diphenyl-1-picrylhydrazyl (dpph*) in alcohols. J Org Chem (2003) 0.99
Activation of chloroform and related trihalomethanes to free radical intermediates in isolated hepatocytes and in the rat in vivo as detected by the ESR-spin trapping technique. Chem Biol Interact (1985) 0.97
Bond strengths of toluenes, anilines, and phenols: to hammett or not. Acc Chem Res (2004) 0.96
Biochemical studies on the metabolic activation of halogenated alkanes. Environ Health Perspect (1985) 0.96
Studies on the metal-ion and lipoxygenase-catalysed breakdown of hydroperoxides using electron-spin-resonance spectroscopy. Biochem J (1987) 0.96
Studies on lipid peroxidation in normal and tumour tissues. The Novikoff rat liver tumour. Biochem J (1986) 0.95
Biochemical and structural changes in rat liver resulting from the parenteral administration of a large dose of sodium salicylate. Biochem Pharmacol (1970) 0.95
Allopurinol pretreatment improves postoperative recovery and reduces lipid peroxidation in patients undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg (1994) 0.95
Effects of carbon tetrachloride on isolated rat liver cells: stimulation of lipid peroxidation and inhibitory action of free-radical scavengers [proceedings]. Biochem Soc Trans (1978) 0.94
Solvolysis of para-substituted cumyl chlorides. Brown and Okamoto's electrophilic substituent constants revisited using continuum solvent models. J Org Chem (2004) 0.94
On the mechanism of the nitric oxide synthase-catalyzed conversion of N omega-hydroxyl-L-arginine to citrulline and nitric oxide. J Biol Chem (1994) 0.93
An improved procedure for the isolation of ghost membranes from human red blood cells. Lipids (1981) 0.93
The role of lipid peroxidation in CCl4-induced damage to liver microsomal enzymes: comparative studies in vitro using microsomes and isolated liver cells. Chem Biol Interact (1981) 0.93
Liver adenosine triphosphate content and bile flow rate in the rat. Biochem J (1970) 0.92
The effect of various anaesthetic techniques on the flow rate, constituents and enzymic composition of rat bile. Biochem Pharmacol (1976) 0.92
Biological antioxidants. Philos Trans R Soc Lond B Biol Sci (1985) 0.92
Estimation of the location of natural alpha-tocopherol in lipid bilayers by 13C-NMR spectroscopy. Biochim Biophys Acta (1985) 0.91
Thermolyses of O-phenyl oxime ethers. A new source of iminyl radicals and a new source of aryloxyl radicals. J Org Chem (2004) 0.91
Free-radical generation by copper ions and hydrogen peroxide. Stimulation by Hepes buffer. Biochem J (1988) 0.91
Absorption and transport of deuterium-substituted 2R,4'R,8'R-alpha-tocopherol in human lipoproteins. Lipids (1988) 0.90
Nascent VLDL from liver perfusions of cynomolgus monkeys are preferentially enriched in RRR- compared with SRR-alpha-tocopherol: studies using deuterated tocopherols. J Lipid Res (1990) 0.90
Nicotinamide-adenine dinucleotides in acute liver injury induced by ethionine, and a comparison with the effects of salicylate. Biochem J (1966) 0.90
A filtration method for the separation of cell sap from the large-particle fraction of rat liver suspensions, enabling the rapid measurement of nucleotide distributions. Biochem J (1970) 0.90
Biokinetics of and discrimination between dietary RRR- and SRR-alpha-tocopherols in the male rat. Lipids (1987) 0.89
Metabolic activation of carbon tetrachloride to a free-radical product: studies using a spin trap. Biochem Soc Trans (1978) 0.89
The metabolism of halothane by hepatocytes: a comparison between free radical spin trapping and lipid peroxidation in relation to cell damage. Chem Biol Interact (1983) 0.88
Spin trapping of free radical products of CC14 activation using pulse radiolysis and high energy radiation procedures. FEBS Lett (1980) 0.88
Detection of free radicals and cholesterol hydroperoxides in blood taken from the coronary sinus of man during percutaneous transluminal coronary angioplasty. Free Radic Res Commun (1991) 0.88
Free radical mechanisms in relation to tissue injury. Proc Nutr Soc (1987) 0.87
Studies on the reduction of nitroblue tetrazolium chloride mediated through the action of NADH and phenazine methosulphate. Chem Biol Interact (1978) 0.87
Lipid peroxidation and lipid antioxidants in normal and tumor cells. Toxicol Pathol (1984) 0.87
A novel procedure for generating both nitric oxide and superoxide in situ from chemical sources at any chosen mole ratio. First application: tyrosine oxidation and a comparison with preformed peroxynitrite. Chem Res Toxicol (2000) 0.87
Free-radical damage in retrolental fibroplasia. Lancet (1970) 0.86
The chemical composition of wasting muscle in cattle suffering from clinical Johne's disease. J Med Microbiol (1968) 0.86
Lipid antioxidants and products of lipid peroxidation as potential tumour protective agents. Biochem Soc Trans (1983) 0.86
Biochemical Pathology in microtime. Panminerva Med (1977) 0.86
Strand cleavage of supercoiled DNA by water-soluble peroxyl radicals. The overlooked importance of peroxyl radical charge. Biochemistry (2000) 0.86