Published in Biochem J on June 15, 1978
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Stimulation of pyruvate transport in metabolizing mitochondria through changes in the transmembrane pH gradient induced by glucagon treatment of rats. Biochem J (1978) 1.54
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Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by alpha-cyano-4-hydroxycinnamate. Biochem J (1974) 4.00
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The specificity and metabolic implications of the inhibition of pyruvate transport in isolated mitochondria and intact tissue preparations by alpha-Cyano-4-hydroxycinnamate and related compounds. Biochem J (1975) 2.15
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The kinetics, substrate and inhibitor specificity of the lactate transporter of Ehrlich-Lettre tumour cells studied with the intracellular pH indicator BCECF. Biochem J (1994) 1.77
Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. J Neurosci (1998) 1.74
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Stimulation of pyruvate transport in metabolizing mitochondria through changes in the transmembrane pH gradient induced by glucagon treatment of rats. Biochem J (1978) 1.54
The mechanism of the inhibition of the mitochondrial pyruvate transportater by alpha-cyanocinnamate derivatives. Biochem J (1976) 1.52
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The kinetics of transport of lactate and pyruvate into rat hepatocytes. Evidence for the presence of a specific carrier similar to that in erythrocytes. Biochem J (1988) 1.50
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Inhibition of mitochondrial pyruvate transport by phenylpyruvate and alpha-ketoisocaproate. Biochim Biophys Acta (1974) 1.47
The intramitochondrial volume measured using sucrose as an extramitochondrial marker overestimates the true matrix volume determined with mannitol. Biochem J (1983) 1.39
Interaction of the erythrocyte lactate transporter (monocarboxylate transporter 1) with an integral 70-kDa membrane glycoprotein of the immunoglobulin superfamily. J Biol Chem (1997) 1.37
The nature of the stimulation of the respiratory chain of rat liver mitochondria by glucagon pretreatment of animals. Biochem J (1982) 1.34
The regulation of branched-chain 2-oxo acid dehydrogenase of liver, kidney and heart by phosphorylation. Biochem J (1981) 1.33
Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulation. Biochem J (1997) 1.32
Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate. Am J Physiol (1999) 1.31
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Identification of the protein responsible for pyruvate transport into rat liver and heart mitochondria by specific labelling with [3H]N-phenylmaleimide. Biochem J (1981) 1.28
Intramitochondrial regulation of fatty acid beta-oxidation occurs between flavoprotein and ubiquinone. A role for changes in the matrix volume. Biochem J (1986) 1.27
The kinetics of transport of lactate and pyruvate into isolated cardiac myocytes from guinea pig. Kinetic evidence for the presence of a carrier distinct from that in erythrocytes and hepatocytes. Biochem J (1989) 1.25
Reconstitution of the L-lactate carrier from rat and rabbit erythrocyte plasma membranes. Biochem J (1988) 1.23
Kinetics of the sarcolemmal lactate carrier in single heart cells using BCECF to measure pHi. Am J Physiol (1994) 1.22
Liver mitochondrial pyrophosphate concentration is increased by Ca2+ and regulates the intramitochondrial volume and adenine nucleotide content. Biochem J (1987) 1.21
Effect of high-intensity exercise training on lactate/H+ transport capacity in human skeletal muscle. Am J Physiol (1999) 1.20
Substrate and inhibitor specificities of the monocarboxylate transporters of single rat heart cells. Am J Physiol (1996) 1.16
Effects of glucagon and Ca2+ on the metabolism of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in isolated rat hepatocytes and plasma membranes. Biochem J (1987) 1.16
Expression and distribution of lactate/monocarboxylate transporter isoforms in pancreatic islets and the exocrine pancreas. Diabetes (2001) 1.15
The effects of glucagon, phenylephrine and insulin on the phosphorylation of cytoplasmic, mitochondrial and membrane-bound proteins of intact liver cells from starved rats. Biochem J (1982) 1.15
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Computer stimulation of the effects of alpha-cyano-4-hydroxycinnamate on gluconeogenesis from L-lactate in rat liver cells. Biochem J (1981) 1.13
A re-evaluation of the role of mitochondrial pyruvate transport in the hormonal control of rat liver mitochondrial pyruvate metabolism. Biochem J (1984) 1.13
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Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich Lettré tumour cell confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function. Biochim Biophys Acta (1996) 1.11
Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain. Neuroscience (2003) 1.10
Substrate and inhibitor specificity of monocarboxylate transport into heart cells and erythrocytes. Further evidence for the existence of two distinct carriers. Biochem J (1990) 1.09
cDNA cloning of MCT1, a monocarboxylate transporter from rat skeletal muscle. Biochim Biophys Acta (1995) 1.09
The involvement of mitochondrial pyruvate transport in the pathways of gluconeogenesis from serine and alanine in isolated rat and mouse liver cells. FEBS Lett (1975) 1.08
cDNA cloning of rat mitochondrial cyclophilin. Biochim Biophys Acta (1997) 1.08
Butyrate can act as a stimulator of growth or inducer of apoptosis in human colonic epithelial cell lines depending on the presence of alternative energy sources. Carcinogenesis (1997) 1.07
A novel postsynaptic density protein: the monocarboxylate transporter MCT2 is co-localized with delta-glutamate receptors in postsynaptic densities of parallel fiber-Purkinje cell synapses. Exp Brain Res (2001) 1.07
Partial inhibition by cyclosporin A of the swelling of liver mitochondria in vivo and in vitro induced by sub-micromolar [Ca2+], but not by butyrate. Evidence for two distinct swelling mechanisms. Biochem J (1990) 1.06
Stimulation of the respiratory chain of rat liver mitochondria between cytochrome c1 and cytochrome c by glucagon treatment of rats. Biochem J (1978) 1.05
The concentration of the mitochondrial pyruvate carrier in rat liver and heart mitochondria determined with alpha-cyano-beta-(1-phenylindol-3-yl)acrylate. Biochem J (1984) 1.04
Chaotropic agents and increased matrix volume enhance binding of mitochondrial cyclophilin to the inner mitochondrial membrane and sensitize the mitochondrial permeability transition to [Ca2+]. Biochemistry (1996) 1.04
Reversible and irreversible inhibition, by stilbenedisulphonates, of lactate transport into rat erythrocytes. Identification of some new high-affinity inhibitors. Biochem J (1991) 1.04
Identification and partial purification of the erythrocyte L-lactate transporter. Biochem J (1992) 1.03
N-terminal protein sequence analysis of the rabbit erythrocyte lactate transporter suggests identity with the cloned monocarboxylate transport protein MCT1. Biochem J (1994) 1.02
Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability. J Neurochem (1999) 1.01
Chronic electrical stimulation increases MCT1 and lactate uptake in red and white skeletal muscle. Am J Physiol (1997) 1.00
The mechanism of action of FK 506. Transplant Proc (1990) 0.99
Isoform-specific regulation of the lactate transporters MCT1 and MCT4 by contractile activity. Am J Physiol Endocrinol Metab (2000) 0.99
Upregulation of the cardiac monocarboxylate transporter MCT1 in a rat model of congestive heart failure. Circulation (2001) 0.98
Glucagon treatment of rats inhibits the accumulation of lysophospholipids by liver mitochondria during preparation and subsequent incubation. Biosci Rep (1984) 0.97
The mechanism of the stimulation of pyruvate transport into rat liver mitochondria by glucagon. Biochem Soc Trans (1977) 0.97
Effects of tyrosine kinase inhibitors on protein kinase-independent systems. FEBS Lett (1993) 0.92
Lactate-proton co-transport and its contribution to interstitial acidification during hypoxia in isolated rat spinal roots. Neuroscience (1993) 0.90
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Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis. Diabetologia (2006) 0.89
Expression of the lactate transporter MCT1 in macrophages. Shock (2000) 0.88
The rôle of mitochondrial pyruvate transport in the stimulation by glucagon and phenylephrine of gluconeogenesis from L-lactate in isolated rat hepatocytes. Biochem J (1981) 0.87
Pyrophosphate metabolism in the perfused heart and isolated heart mitochondria and its role in regulation of mitochondrial function by calcium. Biochem J (1993) 0.86
Characterization of the enhanced transport of L- and D-lactate into human red blood cells infected with Plasmodium falciparum suggests the presence of a novel saturable lactate proton cotransporter. J Biol Chem (1995) 0.86
Inhibition of L-lactate transport and band 3-mediated anion transport in erythrocytes by the novel stilbenedisulphonate N,N,N',N'-tetrabenzyl-4,4'-diaminostilbene-2,2'-disulpho nat e (TBenzDS). Biochim Biophys Acta (1991) 0.86
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Glucagon treatment of rats activates the respiratory chain of liver mitochondria at more than one site. Biochim Biophys Acta (1987) 0.82