PKC-ѳ is dispensable for OX40L-induced TCR-independent Treg proliferation but contributes by enabling IL-2 production from effector T-cells.

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Published in Sci Rep on July 26, 2017

Authors

Khaled Alharshawi1, Alejandra Marinelarena1, Prabhakaran Kumar1, Osama El-Sayed1, Palash Bhattacharya1, Zuoming Sun2, Alan L Epstein3, Ajay V Maker1,4, Bellur S Prabhakar5

Author Affiliations

1: Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, Illinois, USA.
2: Department of Immunology, Beckman Research Institute, City of Hope, Duarte, CA, USA.
3: Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, California, USA.
4: Department of Surgery, Division of Surgical Oncology, University of Illinois College of Medicine, Chicago, Illinois, USA.
5: Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, Illinois, USA. bprabhak@uic.edu.

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