Viscous drag on the flagellum activates Bacillus subtilis entry into the K-state.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28800172)

Published in Mol Microbiol on August 11, 2017

Authors

Christine Diethmaier1, Ravi Chawla2, Alexandra Canzoneri3, Daniel B Kearns4, Pushkar P Lele2, David Dubnau5,6

Author Affiliations

1: Public Health Research Institute Center, New Jersey Medical School, Rutgers University, Newark, NJ, USA.
2: Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station Texas, TX, USA.
3: Department of Biology, Indiana University, Bloomington, IN, USA.
4: Department of Biology, Indiana University, Bloomington, Indiana, 47405.
5: Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers University, Newark, NJ, 07103, USA.
6: Public Health Research Institute Center, New Jersey Medical School, Rutgers University, Newark, NJ, 07103, USA.

Articles cited by this

Chemotaxis in Escherichia coli analysed by three-dimensional tracking. Nature (1972) 23.71

Chemotaxis in bacteria. Annu Rev Biochem (1975) 7.48

Noise in gene expression determines cell fate in Bacillus subtilis. Science (2007) 7.45

The rotary motor of bacterial flagella. Annu Rev Biochem (2002) 7.18

An excitable gene regulatory circuit induces transient cellular differentiation. Nature (2006) 6.03

Regulation of lateral flagella gene transcription in Vibrio parahaemolyticus. J Bacteriol (1986) 4.52

Expression of competence genes in Bacillus subtilis. J Bacteriol (1987) 4.20

Coordinating assembly of a bacterial macromolecular machine. Nat Rev Microbiol (2008) 3.86

Flagellar dynamometer controls swarmer cell differentiation of V. parahaemolyticus. Cell (1988) 3.59

Signal transduction pathway controlling synthesis of a class of degradative enzymes in Bacillus subtilis: expression of the regulatory genes and analysis of mutations in degS and degU. J Bacteriol (1990) 3.57

Successive incorporation of force-generating units in the bacterial rotary motor. Nature (1984) 3.45

Bistability in the Bacillus subtilis K-state (competence) system requires a positive feedback loop. Mol Microbiol (2005) 3.37

Regulation of sigma B levels and activity in Bacillus subtilis. J Bacteriol (1993) 3.17

A molecular clutch disables flagella in the Bacillus subtilis biofilm. Science (2008) 2.86

Incomplete flagellar structures in Escherichia coli mutants. J Bacteriol (1981) 2.77

Localization of Bacillus subtilis sacU(Hy) mutations to two linked genes with similarities to the conserved procaryotic family of two-component signalling systems. J Bacteriol (1988) 2.71

comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis. Mol Microbiol (1995) 2.68

Inverse regulation of biofilm formation and swarming motility by Pseudomonas aeruginosa PA14. J Bacteriol (2007) 2.55

SadB is required for the transition from reversible to irreversible attachment during biofilm formation by Pseudomonas aeruginosa PA14. J Bacteriol (2004) 2.48

Surface contact stimulates the just-in-time deployment of bacterial adhesins. Mol Microbiol (2011) 2.44

Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development. Mol Microbiol (2005) 2.35

Conformational change in the stator of the bacterial flagellar motor. Biochemistry (2001) 2.33

Controlling competence in Bacillus subtilis: shared use of regulators. Microbiology (2003) 2.30

Microarray analysis of the Bacillus subtilis K-state: genome-wide expression changes dependent on ComK. Mol Microbiol (2002) 2.28

DNA microarray analysis of Bacillus subtilis DegU, ComA and PhoP regulons: an approach to comprehensive analysis of B.subtilis two-component regulatory systems. Nucleic Acids Res (2001) 2.13

Mapping of mutations affecting synthesis of exocellular enzymes in Bacillus subtilis. Identity of the sacUh, amyB and pap mutations. Mol Gen Genet (1976) 2.11

Whole-genome analysis of genes regulated by the Bacillus subtilis competence transcription factor ComK. J Bacteriol (2002) 2.01

comK acts as an autoregulatory control switch in the signal transduction route to competence in Bacillus subtilis. J Bacteriol (1994) 1.96

A mechanical signal transmitted by the flagellum controls signalling in Bacillus subtilis. Mol Microbiol (2013) 1.89

Absence of a barrier to backwards rotation of the bacterial flagellar motor demonstrated with optical tweezers. Proc Natl Acad Sci U S A (1997) 1.87

Resurrection of the flagellar rotary motor near zero load. Proc Natl Acad Sci U S A (2008) 1.85

Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach. Nucleic Acids Res (2002) 1.84

An experimental study of GFP-based FRET, with application to intrinsically unstructured proteins. Protein Sci (2007) 1.82

Gradual activation of the response regulator DegU controls serial expression of genes for flagellum formation and biofilm formation in Bacillus subtilis. Mol Microbiol (2007) 1.76

The phosphorylation state of the DegU response regulator acts as a molecular switch allowing either degradative enzyme synthesis or expression of genetic competence in Bacillus subtilis. J Biol Chem (1992) 1.73

DegU co-ordinates multicellular behaviour exhibited by Bacillus subtilis. Mol Microbiol (2007) 1.70

Mutational analysis of the Bacillus subtilis DegU regulator and its phosphorylation by the DegS protein kinase. J Bacteriol (1991) 1.63

Molecular motors of the bacterial flagella. Curr Opin Struct Biol (2008) 1.62

Transient heterogeneity in extracellular protease production by Bacillus subtilis. Mol Syst Biol (2008) 1.60

Solubilization and purification of the MotA/MotB complex of Escherichia coli. Biochemistry (2004) 1.58

Dynamics of mechanosensing in the bacterial flagellar motor. Proc Natl Acad Sci U S A (2013) 1.56

Characterization of the sigD transcription unit of Bacillus subtilis. J Bacteriol (1994) 1.54

Transcriptional organization of a cloned chemotaxis locus of Bacillus subtilis. J Bacteriol (1990) 1.42

A single amino acid substitution responsible for altered flagellar morphology. J Mol Biol (1968) 1.37

Gene position in a long operon governs motility development in Bacillus subtilis. Mol Microbiol (2010) 1.35

The EpsE flagellar clutch is bifunctional and synergizes with EPS biosynthesis to promote Bacillus subtilis biofilm formation. PLoS Genet (2010) 1.35

The pleiotropic response regulator DegU functions as a priming protein in competence development in Bacillus subtilis. Proc Natl Acad Sci U S A (2000) 1.34

Basal expression rate of comK sets a 'switching-window' into the K-state of Bacillus subtilis. Mol Microbiol (2007) 1.33

Bacillus subtilis functional genomics: genome-wide analysis of the DegS-DegU regulon by transcriptomics and proteomics. Mol Genet Genomics (2002) 1.32

Biofilms, flagella, and mechanosensing of surfaces by bacteria. Trends Microbiol (2014) 1.19

A pivotal role for the response regulator DegU in controlling multicellular behaviour. Microbiology (2009) 1.18

Plasmid-encoded ComI inhibits competence in the ancestral 3610 strain of Bacillus subtilis. J Bacteriol (2013) 1.17

Load-dependent assembly of the bacterial flagellar motor. MBio (2013) 1.14

The cell biology of peritrichous flagella in Bacillus subtilis. Mol Microbiol (2012) 1.05

Genetic analysis of Vibrio cholerae monolayer formation reveals a key role for DeltaPsi in the transition to permanent attachment. J Bacteriol (2008) 1.02

Bacterial motility and chemotaxis. Sci Prog (1992) 0.98

Defects in the flagellar motor increase synthesis of poly-γ-glutamate in Bacillus subtilis. J Bacteriol (2013) 0.91

The structure and regulation of flagella in Bacillus subtilis. Annu Rev Genet (2014) 0.91

FliW and FliS function independently to control cytoplasmic flagellin levels in Bacillus subtilis. J Bacteriol (2012) 0.90

Spo0A~P imposes a temporal gate for the bimodal expression of competence in Bacillus subtilis. PLoS Genet (2012) 0.90

Autoregulation of the Bacillus subtilis response regulator gene degU is coupled with the proteolysis of DegU-P by ClpCP. Mol Microbiol (2010) 0.90

Antirepression as a second mechanism of transcriptional activation by a minor groove binding protein. Mol Microbiol (2007) 0.89

Molecular characterization of the flagellar hook in Bacillus subtilis. J Bacteriol (2012) 0.88

Load-sensitive coupling of proton translocation and torque generation in the bacterial flagellar motor. Mol Microbiol (2013) 0.87

SwrAA activates poly-gamma-glutamate synthesis in addition to swarming in Bacillus subtilis. Microbiology (2009) 0.86

A Novel Feedback Loop That Controls Bimodal Expression of Genetic Competence. PLoS Genet (2015) 0.84

Phosphorylated DegU manipulates cell fate differentiation in the Bacillus subtilis biofilm. J Bacteriol (2013) 0.84

Mechanosensing: a regulation sensation. Curr Biol (2015) 0.81

ComGA-RelA interaction and persistence in the Bacillus subtilis K-state. Mol Microbiol (2015) 0.80

The flagellar motor of Caulobacter crescentus generates more torque when a cell swims backward. Nat Phys (2015) 0.75

Biophysical Characterization of Flagellar Motor Functions. J Vis Exp (2017) 0.75