H Leffler

Author PubWeight™ 115.94‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Galectins. Structure and function of a large family of animal lectins. J Biol Chem 1994 4.29
2 Glycolipid receptors for uropathogenic Escherichia coli on human erythrocytes and uroepithelial cells. Infect Immun 1981 3.72
3 Inhibition of experimental ascending urinary tract infection by an epithelial cell-surface receptor analogue. Nature 1982 3.50
4 Identification of an active disaccharide unit of a glycoconjugate receptor for pneumococci attaching to human pharyngeal epithelial cells. J Exp Med 1983 2.80
5 Specificity of binding of a strain of uropathogenic Escherichia coli to Gal alpha 1----4Gal-containing glycosphingolipids. J Biol Chem 1985 2.48
6 Adhesion of Escherichia coli in urinary tract infection. Ciba Found Symp 1981 2.15
7 Aspects on structure and function of pili on uropathogenic Escherichia coli. Prog Allergy 1983 2.11
8 X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution. J Biol Chem 1998 1.99
9 Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340. J Biol Chem 2000 1.89
10 Correlation of P blood group, vesicoureteral reflux, and bacterial attachment in patients with recurrent pyelonephritis. N Engl J Med 1983 1.70
11 Binding specificity of piliated strains of Escherichia coli and Salmonella typhimurium to epithelial cells, saccharomyces cerevisiae cells, and erythrocytes. Infect Immun 1981 1.68
12 Structures of blood group glycosphingolipids of human small intestine. A relation between the expression of fucolipids of epithelial cells and the ABO, Le and Se phenotype of the donor. J Biol Chem 1987 1.67
13 Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides. J Biol Chem 1986 1.60
14 Glycosphingolipid receptors for Pseudomonas aeruginosa. Infect Immun 1990 1.57
15 Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectin. J Biol Chem 1995 1.55
16 Influence of adhesins on the interaction of Escherichia coli with human phagocytes. Infect Immun 1984 1.54
17 L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity. Biochemistry 1993 1.47
18 Receptor-specific agglutination tests for detection of bacteria that bind globoseries glycolipids. J Clin Microbiol 1987 1.47
19 Target cell specificity of wild-type E. coli and mutants and clones with genetically defined adhesins. Prog Food Nutr Sci 1983 1.44
20 Bacterial adherence--a pathogenetic mechanism in urinary tract infections caused by Escherichia coli. Prog Allergy 1983 1.42
21 Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells. Evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway. J Biol Chem 1993 1.39
22 Multiple soluble beta-galactoside-binding lectins from human lung. J Biol Chem 1987 1.36
23 Soluble lactose-binding lectin from rat intestine with two different carbohydrate-binding domains in the same peptide chain. J Biol Chem 1993 1.36
24 Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils. Blood 1998 1.36
25 Macrophage inflammatory protein-2 is required for neutrophil passage across the epithelial barrier of the infected urinary tract. J Immunol 1999 1.36
26 Selected ion monitoring of glycospingolipid mixtures. Identification of several blood group type glycolipids in the small intestine of an individual rabbit. Biomed Mass Spectrom 1979 1.35
27 Glycosphingolipids of human urinary tract epithelial cells as possible receptors for adhering Escherichia coli bacteria. Scand J Infect Dis Suppl 1980 1.35
28 Novel polyfucosylated N-linked glycopeptides with blood group A, H, X, and Y determinants from human small intestinal epithelial cells. J Biol Chem 1989 1.31
29 X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution. J Biol Chem 1993 1.31
30 Virulence-associated traits in Escherichia coli causing first and recurrent episodes of urinary tract infection in children with or without vesicoureteral reflux. J Infect Dis 1984 1.28
31 The receptor repertoire defines the host range for attaching Escherichia coli strains that recognize globo-A. Infect Immun 1991 1.22
32 Binding specificities of wild-type and cloned Escherichia coli strains that recognize globo-A. Infect Immun 1989 1.20
33 Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils. J Immunol 1999 1.18
34 Structure and bacterial receptor activity of a human salivary proline-rich glycoprotein. J Biol Chem 1991 1.15
35 Influence of blood group on the availability of receptors for attachment of uropathogenic Escherichia coli. Infect Immun 1986 1.14
36 Identification of the sulfated monosaccharides of GlyCAM-1, an endothelial-derived ligand for L-selectin. Biochemistry 1994 1.11
37 Strikingly different localization of galectin-3 and galectin-4 in human colon adenocarcinoma T84 cells. Galectin-4 is localized at sites of cell adhesion. J Biol Chem 1997 1.09
38 L-29, a soluble lactose-binding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I. J Biol Chem 1993 1.07
39 P1 blood group and urinary tract infection. Lancet 1981 1.06
40 Distance mapping of protein-binding sites using spin-labeled oligosaccharide ligands. Protein Sci 2001 1.04
41 Binding to galactose alpha 1----4galactose beta-containing receptors as potential diagnostic tool in urinary tract infection. J Clin Microbiol 1987 1.04
42 Sd(a)-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon. Biochem J 2001 1.03
43 Lipopolysaccharide-induced gelatinase granule mobilization primes neutrophils for activation by galectin-3 and formylmethionyl-Leu-Phe. Infect Immun 2001 1.03
44 Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity. Biochemistry 1998 1.03
45 Molecular characterization of alpha-lactalbumin folding variants that induce apoptosis in tumor cells. J Biol Chem 1999 1.01
46 The specific glycosphingolipid composition of human ureteral epithelial cells. J Biochem 1985 1.01
47 The animal lectin galectin-3 interacts with bacterial lipopolysaccharides via two independent sites. J Immunol 1996 1.01
48 Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase. J Biol Chem 1993 1.00
49 Separate oligosaccharide determinants mediate interactions of the low-molecular-weight salivary mucin with neutrophils and bacteria. Biochemistry 1999 0.99
50 Receptor analogues and anti-pili antibodies as inhibitors of bacterial attachment in vivo and in vitro. Ann N Y Acad Sci 1983 0.97
51 Gangliotetraosylceramide is a major glycolipid of epithelial cells of mouse small intestine. FEBS Lett 1982 0.96
52 A sialoglycoprotein complex linked to the microvillus cytoskeleton acts as a receptor for pilus (AF/R1) mediated adhesion of enteropathogenic Escherichia coli (RDEC-1) in rabbit small intestine. J Cell Biol 1991 0.95
53 Different binding specificities of P. mirabilis compared to E. coli. Scand J Infect Dis Suppl 1982 0.95
54 Galectin-4 and galectin-6 are two closely related lectins expressed in mouse gastrointestinal tract. J Biol Chem 1998 0.94
55 Glycosphingolipids of rat tissues. Different composition of epithelial and nonepithelial cells of small intestine. J Biol Chem 1982 0.93
56 Assignment of 1H, 15N and 13C resonances of the carbohydrate recognition domain of human galectin-3. J Biomol NMR 2001 0.92
57 Chemical and clinical studies on the interaction of Escherichia coli with host glycolipid receptors in urinary tract infection. Scand J Infect Dis Suppl 1982 0.91
58 Recent progress in the understanding of the role of bacterial adhesion in the pathogenesis of urinary tract infection. Infection 1983 0.90
59 Pleiotropic drug resistance and gene amplification in a SEWA mouse tumor cell line. Complex relations revealed by drug uptake data, and lipid and protein analysis. Exp Cell Res 1985 0.90
60 The structure of sphingomyelin of the honey bee (Apis mellifera). Biochim Biophys Acta 1972 0.89
61 Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes. J Biol Chem 1995 0.89
62 Non-antibody-containing fractions of breast milk inhibit epithelial attachment of Streptococcus pneumoniae and Haemophilus influenzae. Lancet 1985 0.88
63 Sulfated lewis X determinants as a major structural motif in glycans from LS174T-HM7 human colon carcinoma mucin. J Biol Chem 1997 0.88
64 Isolation and expression of a gene encoding L-14-II, a new human soluble lactose-binding lectin. J Biol Chem 1992 0.88
65 Glycoconjugate receptors for bacteria attaching to mucosal sites: examples for Escherichia coli and Streptococcus pneumoniae. Adv Exp Med Biol 1987 0.87
66 Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. Structure 1995 0.87
67 Possible interaction between animal lectins and bacterial carbohydrates. Methods Enzymol 1994 0.86
68 Glycosphingolipids and the differentiation of intestinal epithelium. Exp Cell Res 1981 0.86
69 Characterization of the forssman glycolipid hapten of horse kidney by mass spectrometry. J Biol Chem 1974 0.86
70 Protein identification by in-gel digestion, high-performance liquid chromatography, and mass spectrometry: peptide analysis by complementary ionization techniques. J Am Soc Mass Spectrom 2001 0.86
71 Fecal excretion of intestinal glycosphingolipids by newborns and young children. FEBS Lett 1987 0.86
72 Blood group non-secretors have an increased inflammatory response to urinary tract infection. Scand J Infect Dis 1992 0.85
73 Blood group type glycosphingolipids from the small intestine of different animals analysed by mass spectrometry and thin-layer chromatography. A note on species diversity. J Biochem 1981 0.85
74 Specific pattern of glycosphingolipids enriched in a mucosa scraping of human small intestine. FEBS Lett 1979 0.83
75 Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13. Genomics 1993 0.82
76 The preparative separation of sialic acid-containing lipids from sulphate group-containing glycolipids from small intestine of different animals. Analysis by thin-layer chromatography and detection of novel species. J Biochem 1983 0.82
77 Non-antibiotic prevention of urinary tract infection. Infection 1985 0.81
78 Non-antibiotic prevention of urinary tract infection. Infection 1984 0.81
79 P blood group and proneness to urinary tract infection in Japanese children. Scand J Infect Dis 1989 0.81
80 Human breast carcinoma cDNA encoding a galactoside-binding lectin homologous to mouse Mac-2 antigen. Gene 1991 0.81
81 Isolation and partial characterization of blood group A and H active glycosphingolipids of rat small intestine. J Biol Chem 1982 0.81
82 Thioureido N-acetyllactosamine derivatives as potent galectin-7 and 9N inhibitors. Bioorg Med Chem 2005 0.80
83 The high-molecular-weight human mucin is the primary salivary carrier of ABH, Le(a), and Le(b) blood group antigens. Crit Rev Oral Biol Med 1993 0.80
84 Specific adherence of Candida tropicalis to lysophospholipids. Biochemistry 1994 0.79
85 A novel sulfoglycosphingolipid of mouse small intestine, IV3-sulfogangliotetraosylceramide, demonstrated by negative ion fast atom bombardment mass spectrometry. J Biol Chem 1986 0.79
86 Studies on differentiating epithelial cells of rat small intestine. Alterations in the lipophilic part of glycosphingolipids during cell migration from crypt villus tip. Biochim Biophys Acta 1982 0.79
87 Separation and characterization of hematosides with different sialic acids and ceramides from rat small intestine. Different composition of epithelial cells versus non-epithelial tissue and of duodenum versus jejunum-ileum. J Biochem 1981 0.78
88 Sequence, structure, and chromosomal mapping of the mouse Lgals6 gene, encoding galectin-6. J Biol Chem 1998 0.78
89 Molecular mechanisms of adhesion of Streptococcus pneumoniae to human oropharyngeal epithelial cells. Scand J Infect Dis Suppl 1983 0.77
90 Glycoconjugate receptors involved in the adhesion of Escherichia coli and Streptococcus pneumoniae to epithelial cells. J Dent Res 1984 0.76
91 Sequence and specificity of a soluble lactose-binding lectin from Xenopus laevis skin. J Biol Chem 1992 0.76
92 Multiple soluble vertebrate galactoside-binding lectins. Biochimie 1988 0.76
93 Crystallization and preliminary X-ray diffraction analysis of the human dimeric S-Lac lectin (L-14-II). J Mol Biol 1993 0.76
94 Glycolipids of rat small intestine. Characterization of a novel blood group H-active triglycosylceramide. Biochim Biophys Acta 1980 0.76
95 Inhibition of bacterial attachment: examples from the urinary and respiratory tracts. Curr Top Microbiol Immunol 1990 0.76
96 Palmitoyl carnitine, a lysophospholipase-transacylase inhibitor, prevents Candida adherence in vitro. FEMS Microbiol Lett 1997 0.76
97 Characterization of cerebroside (monoglycosylceramide) from the sea anemone, Metridium senile. Identification of the major long-chain base as an unusual dienic base with a methyl branch at a double bond. Biochim Biophys Acta 1979 0.76
98 [Bacterial binding and urinary tract infections]. Lakartidningen 1982 0.75
99 Human blood group A-positive and -negative strains of rat. Chemical basis as shown by fucolipids of small intestine. FEBS Lett 1980 0.75
100 Soluble lactose-binding lectins from chicken and rat. Methods Enzymol 1987 0.75
101 Demonstration of complexity of the glycosphingolipid fraction of rat small intestine. Biochem Biophys Res Commun 1980 0.75
102 Sequencing of oligosaccharides by mass spectrometry applied on a 12-sugar glycolipid. FEBS Lett 1981 0.75
103 Structure determination of blood group type glycolipids of cat small intestine by mass fragmentography. FEBS Lett 1978 0.75
104 Attachment of Streptococcus pneumoniae to human pharyngeal epithelial cells in vitro--mechanism of binding. Otolaryngol Head Neck Surg 1984 0.75
105 Identifying bacterial receptor proteins and quantifying strength of interactions they mediate. Methods Enzymol 1995 0.75
106 Chemical characterization of penta-, hexa-, hepta-, octa-, and nonaglycosylceramides of rat small intestine having a globoside-like terminus. J Biol Chem 1982 0.75
107 Structural characterization of glycolipids of rat small intestine having one to eight hexoses in a linear sequence. Arch Biochem Biophys 1982 0.75