Exosomes Derived From Natural Killer Cells Exert Therapeutic Effect in Melanoma.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28819459)

Published in Theranostics on July 07, 2017

Authors

Liya Zhu1, Senthilkumar Kalimuthu1, Prakash Gangadaran1, Ji Min Oh1, Ho Won Lee1, Se Hwan Baek1, Shin Young Jeong1, Sang-Woo Lee1, Jaetae Lee1, Byeong-Cheol Ahn1

Author Affiliations

1: Department of Nuclear Medicine, Kyungpook National University School of Medicine and Hospital, Daegu 700-721, Republic of Korea.

Articles cited by this

Dendritic cells and the control of immunity. Nature (1998) 56.54

Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol (2006) 13.29

Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science (2002) 12.75

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med (2012) 11.14

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nat Med (1998) 6.36

Cancer immunotherapy via dendritic cells. Nat Rev Cancer (2012) 5.37

Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases. Microbiol Mol Biol Rev (2011) 5.02

Malignant melanoma: genetics and therapeutics in the genomic era. Genes Dev (2006) 4.24

Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation. Cancer Res (2003) 4.03

Functional significance of the perforin/granzyme cell death pathway. Nat Rev Immunol (2002) 3.96

Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J Exp Med (2002) 3.02

Microenvironmental pH is a key factor for exosome traffic in tumor cells. J Biol Chem (2009) 2.99

Systematic review of medical treatment in melanoma: current status and future prospects. Oncologist (2011) 2.89

Immunotype and immunohistologic characteristics of tumor-infiltrating immune cells are associated with clinical outcome in metastatic melanoma. Cancer Res (2012) 2.48

Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell-depleted stem cell transplantation. Blood (2014) 1.78

Adoptive transfer of autologous natural killer cells leads to high levels of circulating natural killer cells but does not mediate tumor regression. Clin Cancer Res (2011) 1.62

Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth. Cancer Lett (2013) 1.51

Exosomes derived from mesenchymal stem cells suppress angiogenesis by down-regulating VEGF expression in breast cancer cells. PLoS One (2013) 1.48

Exosomes derived from genetically modified DC expressing FasL are anti-inflammatory and immunosuppressive. Mol Ther (2005) 1.38

A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model. Cancer Res (2005) 1.34

Three-dimensional ultrasound biomicroscopy for xenograft growth analysis. Ultrasound Med Biol (2005) 1.27

Immune surveillance properties of human NK cell-derived exosomes. J Immunol (2012) 1.26

Body fluid exosomes promote secretion of inflammatory cytokines in monocytic cells via Toll-like receptor signaling. J Biol Chem (2013) 1.22

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas. Proc Natl Acad Sci U S A (2008) 1.18

In vivo cell tracking with bioluminescence imaging. Nucl Med Mol Imaging (2014) 1.08

Targeting natural killer cells in cancer immunotherapy. Nat Immunol (2016) 1.06

The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity. Front Immunol (2013) 1.06

Melanoma cells inhibit NK cell functions. Cancer Res (2012) 1.04

Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition. Clin Exp Immunol (2009) 0.99

Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro. Blood (2013) 0.98

Natural Killer Cells for Immunotherapy - Advantages of the NK-92 Cell Line over Blood NK Cells. Front Immunol (2016) 0.95

The potential of exosomes in immunotherapy of cancer. Blood Cells Mol Dis (2005) 0.92

Functional significance of macrophage-derived exosomes in inflammation and pain. Pain (2014) 0.92

Dendritic cell-derived exosomes for cancer therapy. J Clin Invest (2016) 0.91

Immunotherapy in melanoma: Recent advances and future directions. Eur J Surg Oncol (2016) 0.87

Engineering NK Cells Modified With an EGFRvIII-specific Chimeric Antigen Receptor to Overexpress CXCR4 Improves Immunotherapy of CXCL12/SDF-1α-secreting Glioblastoma. J Immunother (2015) 0.87

The human exosome and disease. Adv Exp Med Biol (2011) 0.86

Expression of c-Kit, p-ERK and cyclin D1 in malignant melanoma: an immunohistochemical study and analysis of prognostic value. J Dermatol Sci (2011) 0.85

Melanoma immunoediting by NK cells. Oncoimmunology (2012) 0.84

Cytotoxic effect of lymphocytes from pregnant mice on cultivated tumor cells. I. Specificity, nature of effector cells and blocking by serum. Int J Cancer (1975) 0.83

TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma. Sci Rep (2015) 0.83

A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases. Oncotarget (2016) 0.82

Exosomes derived from mature dendritic cells increase endothelial inflammation and atherosclerosis via membrane TNF-α mediated NF-κB pathway. J Cell Mol Med (2016) 0.82

NK cell-released exosomes: Natural nanobullets against tumors. Oncoimmunology (2013) 0.82

Human B Cell-Derived Lymphoblastoid Cell Lines Constitutively Produce Fas Ligand and Secrete MHCII(+)FasL(+) Killer Exosomes. Front Immunol (2014) 0.81

Expanded and armed natural killer cells for cancer treatment. Cytotherapy (2016) 0.78

Perforin-dependent direct cytotoxicity in natural killer cells induces considerable knockdown of spontaneous lung metastases and computer modelling-proven tumor cell dormancy in a HT29 human colon cancer xenograft mouse model. Mol Cancer (2014) 0.78

Evaluation of therapeutic effects of natural killer (NK) cell-based immunotherapy in mice using in vivo apoptosis bioimaging with a caspase-3 sensor. FASEB J (2014) 0.78

Impact of cytokine- and FasL-induced apoptosis in the beta-cell line NIT-1. Horm Metab Res (2008) 0.77

A Pretargeted Approach for the Multimodal PET/NIRF Imaging of Colorectal Cancer. Theranostics (2016) 0.75

In Vivo therapeutic potential of mesenchymal stem cell-derived extracellular vesicles with optical imaging reporter in tumor mice model. Sci Rep (2016) 0.75