Published in J Cell Biol on October 01, 1987
Dynamics of DNA replication factories in living cells. J Cell Biol (2000) 4.93
Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences. J Cell Biol (1992) 4.39
Identification of a novel nuclear domain. J Cell Biol (1991) 3.91
Mapping replicational sites in the eucaryotic cell nucleus. J Cell Biol (1989) 3.89
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Genes Dev (2000) 3.86
DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol Cell Biol (2001) 3.78
Y-family DNA polymerases and their role in tolerance of cellular DNA damage. Nat Rev Mol Cell Biol (2012) 3.43
Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization. EMBO J (1999) 3.05
BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication. J Cell Biol (1995) 3.02
Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies. J Cell Biol (1995) 2.93
Cell proliferation in human coronary arteries. Proc Natl Acad Sci U S A (1990) 2.90
Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis. Mol Cell Biol (2001) 2.85
Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells. Genes Dev (2001) 2.53
Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex. J Cell Biol (1999) 2.43
Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo. Proc Natl Acad Sci U S A (2003) 2.36
Continuation of neurogenesis in the hippocampus of the adult macaque monkey. Proc Natl Acad Sci U S A (1999) 2.33
Immunocytochemical analysis of the coiled body in the cell cycle and during cell proliferation. Proc Natl Acad Sci U S A (1993) 2.13
The generation, migration, and differentiation of olfactory neurons in the adult primate brain. Proc Natl Acad Sci U S A (2001) 2.05
Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression. Proc Natl Acad Sci U S A (1991) 1.99
Nuclear protein p68 is an RNA-dependent ATPase. EMBO J (1989) 1.98
Spatial organization of large-scale chromatin domains in the nucleus: a magnified view of single chromosome territories. J Cell Biol (1997) 1.94
DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. EMBO J (1994) 1.88
Recruitment of phosphorylated chromatin assembly factor 1 to chromatin after UV irradiation of human cells. J Cell Biol (1998) 1.84
Changes in cyclin/proliferating cell nuclear antigen distribution during DNA repair synthesis. J Cell Biol (1988) 1.79
A DNA polymerase-{alpha}{middle dot}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells. J Biol Chem (2008) 1.77
Neural stem and progenitor cells shorten S-phase on commitment to neuron production. Nat Commun (2011) 1.75
An inhibitor of the in vitro elongation reaction of simian virus 40 DNA replication is overcome by proliferating-cell nuclear antigen. Proc Natl Acad Sci U S A (1988) 1.72
Identification of nuclear pre-replication centers poised for DNA synthesis in Xenopus egg extracts: immunolocalization study of replication protein A. J Cell Biol (1992) 1.72
Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors. Mol Biol Cell (1996) 1.72
Mapping and use of a sequence that targets DNA ligase I to sites of DNA replication in vivo. J Cell Biol (1997) 1.70
Dynamics of pre-replication complex proteins during the cell division cycle. Philos Trans R Soc Lond B Biol Sci (2004) 1.65
LAP (NF-IL-6), a tissue-specific transcriptional activator, is an inhibitor of hepatoma cell proliferation. EMBO J (1994) 1.64
Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures. Mol Cell Biol (2005) 1.63
Cell-cycle-related staining patterns of anti-proliferating cell nuclear antigen monoclonal antibodies. Comparison with BrdUrd labeling and Ki-67 staining. Am J Pathol (1991) 1.63
The N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replication. EMBO J (1995) 1.59
Periodic biosynthesis of the human M-phase promoting factor catalytic subunit p34 during the cell cycle. Mol Cell Biol (1990) 1.54
A geminivirus induces expression of a host DNA synthesis protein in terminally differentiated plant cells. Plant Cell (1995) 1.52
Obstructive jaundice alters proliferating cell nuclear antigen expression in rat small intestine. World J Surg (2003) 1.49
Head and/or CaaX domain deletions of lamin proteins disrupt preformed lamin A and C but not lamin B structure in mammalian cells. Mol Biol Cell (2000) 1.47
RAD21L, a novel cohesin subunit implicated in linking homologous chromosomes in mammalian meiosis. J Cell Biol (2011) 1.46
Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1. J Biol Chem (2010) 1.43
Proliferating cellular nuclear antigen expression as a marker of perivascular macrophages in simian immunodeficiency virus encephalitis. Am J Pathol (2002) 1.38
Disruption of the FEN-1/PCNA interaction results in DNA replication defects, pulmonary hypoplasia, pancytopenia, and newborn lethality in mice. Mol Cell Biol (2007) 1.37
Mutagen sensitivity and suppression of position-effect variegation result from mutations in mus209, the Drosophila gene encoding PCNA. EMBO J (1994) 1.36
Molecular cloning of cDNA encoding mouse Cdc21 and CDC46 homologs and characterization of the products: physical interaction between P1(MCM3) and CDC46 proteins. Nucleic Acids Res (1995) 1.35
A subunit of the anaphase-promoting complex is a centromere-associated protein in mammalian cells. Mol Cell Biol (1998) 1.33
A novel amniote model of epimorphic regeneration: the leopard gecko, Eublepharis macularius. BMC Dev Biol (2011) 1.33
PCNA binding proteins in Drosophila melanogaster : the analysis of a conserved PCNA binding domain. Nucleic Acids Res (1998) 1.32
Which proliferation markers for routine immunohistology? A comparison of five antibodies. J Clin Pathol (1994) 1.30
Reactive astrocytosis from excitotoxic injury in hippocampal organ culture parallels that seen in vivo. J Cereb Blood Flow Metab (1997) 1.22
The yeast silent information regulator Sir4p anchors and partitions plasmids. Mol Cell Biol (1997) 1.21
Comparative analysis of the intracellular localization of c-Myc, c-Fos, and replicative proteins during cell cycle progression. Mol Cell Biol (1992) 1.16
FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures. J Biol Chem (2009) 1.15
Nuclear factor I is specifically targeted to discrete subnuclear sites in adenovirus type 2-infected cells. J Virol (1992) 1.15
Analysis of replication factories in human cells by super-resolution light microscopy. BMC Cell Biol (2009) 1.15
p21(CIP1) Controls proliferating cell nuclear antigen level in adult cardiomyocytes. Mol Cell Biol (2003) 1.14
Proliferation cell nuclear antigen (clone 19A2) correlates with 5-bromo-2-deoxyuridine labelling in human colonic epithelium. Gut (1993) 1.12
Plasminogen activator inhibitor-1 limits liver injury and facilitates regeneration after acetaminophen overdose. Toxicol Sci (2008) 1.11
Control of spermatogenesis in mice by the cyclin D-dependent kinase inhibitors p18(Ink4c) and p19(Ink4d). Mol Cell Biol (2001) 1.10
Time course of airway remodelling after an acute chlorine gas exposure in mice. Respir Res (2008) 1.08
Growth fraction estimation of malignant lymphomas in formalin-fixed paraffin-embedded tissue using anti-PCNA/Cyclin 19A2. Correlation with Ki-67 labeling. Am J Pathol (1991) 1.08
A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen. Proc Natl Acad Sci U S A (2001) 1.08
ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin. J Cell Biol (2012) 1.07
Involvement of proliferating cell nuclear antigen (cyclin) in DNA replication in living cells. Mol Cell Biol (1989) 1.07
The nuclear membrane determines the timing of DNA replication in Xenopus egg extracts. J Cell Biol (1991) 1.06
The structural protein ODV-EC27 of Autographa californica nucleopolyhedrovirus is a multifunctional viral cyclin. Proc Natl Acad Sci U S A (1998) 1.05
Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin. EMBO J (2011) 1.05
Increased p22(phox)/Nox4 expression is involved in remodeling through hydrogen peroxide signaling in experimental persistent pulmonary hypertension of the newborn. Antioxid Redox Signal (2013) 1.04
Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization. J Clin Invest (1993) 1.04
Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth. Mol Cancer Ther (2011) 1.02
Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth. Mol Pharmacol (2012) 1.02
Heterologous expression of the human cyclin-dependent kinase inhibitor p21Cip1 in the fission yeast, Schizosaccharomyces pombe reveals a role for PCNA in the chk1+ cell cycle checkpoint pathway. Mol Biol Cell (1996) 1.01
Molecular markers for breast cancer: prediction on tumor behavior. Dis Markers (2014) 1.01
Proliferation of hepatic stellate cells is inhibited by phosphorylation of CREB on serine 133. J Clin Invest (1997) 1.01
The cdk7-cyclin H-MAT1 complex associated with TFIIH is localized in coiled bodies. Mol Biol Cell (1997) 1.01
In vivo study of the nucleosome assembly functions of ASF1 histone chaperones in human cells. Mol Cell Biol (2008) 1.00
Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation. Nucleic Acids Res (2004) 1.00
Replication of centromeric heterochromatin in mouse fibroblasts takes place in early, middle, and late S phase. Histochem Cell Biol (2005) 0.99
Proliferating cell nuclear antigen in oesophageal diseases; correlation with transforming growth factor alpha expression. Gut (1992) 0.99
Evidence for a replication function of FFA-1, the Xenopus orthologue of Werner syndrome protein. J Cell Biol (2001) 0.98
Absence of autoantigen Ku in mature human neutrophils and human promyelocytic leukemia line (HL-60) cells and lymphocytes undergoing apoptosis. J Exp Med (1995) 0.97
Analysis of proliferating hepatocytes using a monoclonal antibody against proliferating cell nuclear antigen/cyclin in embedded tissues from various liver diseases fixed in formaldehyde. Am J Pathol (1992) 0.97
CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. Nucleic Acids Res (2014) 0.97
Neurogenesis in zebrafish - from embryo to adult. Neural Dev (2013) 0.96
Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigens. Mol Cell Biol (1991) 0.95
Localization of proteasomes and proteasomal proteolysis in the mammalian interphase cell nucleus by systematic application of immunocytochemistry. Histochem Cell Biol (2007) 0.93
Expression of proliferation associated antigens and detection of numerical chromosome aberrations in primary human liver tumours: relevance to tumour characteristics and prognosis. J Clin Pathol (1998) 0.93
Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2. J Biol Chem (2009) 0.92
Proliferating cell nuclear antigen expression in non-cycling cells may be induced by growth factors in vivo. Br J Cancer (1994) 0.92
Distribution of p27(KIP1), cyclin D1, and proliferating cell nuclear antigen after retinal detachment. Graefes Arch Clin Exp Ophthalmol (2004) 0.91
Rapamycin (sirolimus) inhibits proliferating cell nuclear antigen expression and blocks cell cycle in the G1 phase in human keratinocyte stem cells. J Clin Invest (1997) 0.91
A Cajal body-independent pathway for telomerase trafficking in mice. Exp Cell Res (2010) 0.91
Phosphorylation of extracellular signal-regulated kinase and p27(KIP1) after retinal detachment. Graefes Arch Clin Exp Ophthalmol (2005) 0.90
DNA damage response pathway and replication fork stress during oligonucleotide directed gene editing. Mol Ther Nucleic Acids (2012) 0.90
Protective mechanism of glutamine on the expression of proliferating cell nuclear antigen after cisplatin-induced intestinal mucosal injury. Pediatr Surg Int (2011) 0.89
Proenkephalin is a nuclear protein responsive to growth arrest and differentiation signals. J Cell Biol (1995) 0.89
Growth fraction in non-small cell lung cancer estimated by proliferating cell nuclear antigen and comparison with Ki-67 labeling and DNA flow cytometry data. Am J Pathol (1992) 0.88
Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype. Am J Physiol Cell Physiol (2015) 0.87
High resolution two-dimensional electrophoresis of proteins. J Biol Chem (1975) 133.45
"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem (1981) 71.15
Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography. Eur J Biochem (1975) 56.72
Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. Science (1982) 10.61
Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine. Adv Immunol (1982) 9.73
Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta. Nature (1987) 8.28
Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein. Nature (1987) 6.45
The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro. Nature (1987) 4.43
Autoantibody to a nuclear antigen in proliferating cells. J Immunol (1978) 4.36
An auxiliary protein for DNA polymerase-delta from fetal calf thymus. J Biol Chem (1986) 4.06
Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cells: subdivision of S phase. Proc Natl Acad Sci U S A (1985) 3.62
A search for differential polypeptide synthesis throughout the cell cycle of HeLa cells. J Cell Biol (1980) 3.50
Identity of the proliferating cell nuclear antigen and cyclin. Nature (1984) 3.44
Structural organizations of replicon domains during DNA synthetic phase in the mammalian nucleus. Exp Cell Res (1986) 3.17
Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine. Proc Natl Acad Sci U S A (1983) 3.14
Multienzyme complex for metabolic channeling in mammalian DNA replication. Proc Natl Acad Sci U S A (1980) 3.12
Cloning and sequence of the human nuclear protein cyclin: homology with DNA-binding proteins. Proc Natl Acad Sci U S A (1987) 3.05
A nuclear antigen associated with cell proliferation and blast transformation. J Exp Med (1981) 2.82
Changes in the nuclear distribution of cyclin (PCNA) but not its synthesis depend on DNA replication. EMBO J (1985) 2.28
Architecture and polypeptide composition of HeLa cytoskeletons. Modification of cytoarchitectural polypeptides during mitosis. J Mol Biol (1982) 2.13
Synthesis of the nuclear protein cyclin (PCNA) and its relationship with DNA replication. Exp Cell Res (1986) 1.92
Characterization of proliferating cell nuclear antigen recognized by autoantibodies in lupus sera. J Exp Med (1984) 1.79
Rapid incorporation of label from ribonucleoside disphosphates into DNA by a cell-free high molecular weight fraction from animal cell nuclei. Cell (1983) 1.76
Molecular cloning of cDNA coding for rat proliferating cell nuclear antigen (PCNA)/cyclin. EMBO J (1987) 1.75
Induction of the nuclear protein 'cyclin' in quiescent mouse 3T3 cells stimulated by serum and growth factors. Correlation with DNA synthesis. EMBO J (1984) 1.36
Nuclear patterns of cyclin (PCNA) antigen distribution subdivide S-phase in cultured cells--some applications of PCNA antibodies. Leuk Res (1986) 1.26
Epidermal growth factor inhibits the synthesis of the nuclear protein cyclin in A431 human carcinoma cells. Proc Natl Acad Sci U S A (1984) 1.22
Synthesis of DNA polymerase alpha analyzed by immunoprecipitation from synchronously proliferating cells. Biochemistry (1986) 1.12
Inhibitor evidence for allosteric interaction in the replitase multienzyme complex. Nature (1983) 1.12
Activity levels of mouse DNA polymerase alpha-primase complex (DNA replicase) and DNA polymerase alpha, free from primase activity in synchronized cells, and a comparison of their catalytic properties. Eur J Biochem (1986) 0.88
Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta. Nature (1987) 8.28
Complexity of the early genetic response to growth factors in mouse fibroblasts. Mol Cell Biol (1988) 5.21
Cloning and sequence of the human nuclear protein cyclin: homology with DNA-binding proteins. Proc Natl Acad Sci U S A (1987) 3.05
Changes in the nuclear distribution of cyclin (PCNA) but not its synthesis depend on DNA replication. EMBO J (1985) 2.28
Structure, mapping and expression of a growth factor inducible gene encoding a putative nuclear hormonal binding receptor. EMBO J (1989) 1.98
Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein. Cell Growth Differ (1991) 1.80
Induction of the nuclear protein 'cyclin' in quiescent mouse 3T3 cells stimulated by serum and growth factors. Correlation with DNA synthesis. EMBO J (1984) 1.36
Bombesin induces c-fos and c-myc expression in quiescent Swiss 3T3 cells. Comparative study with other mitogens. Exp Cell Res (1987) 1.19
Identification of an immediate early gene, pghs-B, whose protein product has prostaglandin synthase/cyclooxygenase activity. Cell Growth Differ (1992) 1.11
The product of a novel growth factor-activated gene, fic, is a biologically active "C-C"-type cytokine. Mol Cell Biol (1993) 1.09
Induction of the nuclear protein cyclin in serum-stimulated quiescent 3T3 cells is independent of DNA synthesis. Exp Cell Res (1985) 1.02
Expression of constitutively active IkappaB beta in T cells of transgenic mice: persistent NF-kappaB activity is required for T-cell immune responses. Mol Cell Biol (1998) 0.95
Identification of growth-factor-inducible genes in mouse fibroblasts. Cold Spring Harb Symp Quant Biol (1988) 0.87
The macrophage-colony stimulating factor gene is a growth factor-inducible immediate early gene in fibroblasts. New Biol (1991) 0.77
Effect of pH on the induction of competence and progression to the S-phase in mouse fibroblasts. FEBS Lett (1986) 0.76