Published in J Biomed Sci on September 19, 2017
Biochemistry and molecular cell biology of diabetic complications. Nature (2001) 25.43
Oxidants, oxidative stress and the biology of ageing. Nature (2000) 23.21
Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem (2006) 22.87
Free radicals in the physiological control of cell function. Physiol Rev (2002) 19.62
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature (2000) 12.33
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med (2001) 11.92
Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol (1990) 11.00
Free radicals in biological materials. Nature (1954) 8.71
Role of oxidative stress in development of complications in diabetes. Diabetes (1991) 8.27
The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature (1999) 7.85
Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol (2003) 6.78
Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes (1999) 5.96
Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature (2001) 5.60
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett (1997) 5.21
Organelle-specific initiation of cell death pathways. Nat Cell Biol (2001) 5.03
Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction? Diabetes (2003) 4.40
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell (2005) 4.36
Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol Pathol (2003) 3.99
Role of oxidative stress in cardiovascular diseases. J Hypertens (2000) 3.73
Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation (2002) 3.71
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc Natl Acad Sci U S A (2008) 3.68
Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo. Free Radic Biol Med (2000) 3.53
Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci (2006) 3.41
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci U S A (2000) 3.36
Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling. Am J Respir Crit Care Med (2002) 3.36
The role of alterations in membrane lipid composition in enabling physiological adaptation of organisms to their physical environment. Prog Lipid Res (1990) 3.29
Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci (1997) 3.08
Natural history of colonization with vancomycin-resistant Enterococcus faecium. Infect Control Hosp Epidemiol (1995) 2.97
Free radicals, antioxidants in disease and health. Int J Biomed Sci (2008) 2.89
Cerebral function in diabetes mellitus. Diabetologia (1994) 2.82
Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes. Biochem J (1987) 2.82
Mitochondrial reactive oxygen species in cell death signaling. Biochimie (2002) 2.75
Hyperglycemic pseudohypoxia and diabetic complications. Diabetes (1993) 2.62
Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences. Free Radic Biol Med (1990) 2.57
Protein glycation, diabetes, and aging. Recent Prog Horm Res (2001) 2.51
Biologically relevant metal ion-dependent hydroxyl radical generation. An update. FEBS Lett (1992) 2.49
Recent advances in the monitoring and management of diabetic ketoacidosis. QJM (2004) 2.33
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers. J Clin Invest (2012) 2.33
Antioxidants, oxidative stress, and degenerative neurological disorders. Proc Soc Exp Biol Med (1999) 2.32
Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Ann Neurol (2005) 2.20
Hydrogen peroxide production during experimental protein glycation. FEBS Lett (1990) 2.15
Detection of nitrotyrosine in the diabetic plasma: evidence of oxidative stress. Diabetologia (2001) 2.15
Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors. Circ Res (2000) 2.15
Protein oxidation in the brain in Alzheimer's disease. Neuroscience (2001) 2.00
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence. Biochemistry (2003) 1.89
Evidence of neuronal oxidative damage in Alzheimer's disease. Am J Pathol (1996) 1.87
Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease. Physiol Rev (2007) 1.79
Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration. FASEB J (2009) 1.78
The missing link: a single unifying mechanism for diabetic complications. Kidney Int Suppl (2000) 1.69
Direct activation of mitochondrial K(ATP) channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts. Cardiovasc Res (2001) 1.69
Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease. Free Radic Biol Med (2012) 1.67
The voltage-dependent anion channel-1 modulates apoptotic cell death. Cell Death Differ (2005) 1.63
Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease. Exp Neurol (2009) 1.61
The Rotterdam Study: 2016 objectives and design update. Eur J Epidemiol (2015) 1.61
Increased risk of Alzheimer's disease in Type II diabetes: insulin resistance of the brain or insulin-induced amyloid pathology? Biochem Soc Trans (2005) 1.59
Associations between criteria air pollutants and asthma. Environ Health Perspect (1995) 1.57
Regional membrane phospholipid alterations in Alzheimer's disease. Neurochem Res (1998) 1.57
Hexosamines and insulin resistance. Diabetes (1996) 1.57
Free radicals in disease processes: a compilation of cause and consequence. Free Radic Res Commun (1993) 1.56
Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta (2006) 1.56
Oxidative stress and diabetes-associated complications. Endocr Pract (2006) 1.54
Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD. Neurobiol Aging (2005) 1.52
Three models of free radical-induced cell injury. Chem Biol Interact (1989) 1.35
Alzheimer's disease--synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts. J Neural Transm (Vienna) (1998) 1.35
Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease. Am J Med (2000) 1.34
Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose. Kidney Int (2002) 1.31
Evolution in the conceptualization of dementia and Alzheimer's disease: Greco-Roman period to the 1960s. Neurobiol Aging (1998) 1.31
Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway. J Clin Invest (1994) 1.31
Causes and consequences of disturbances of cerebral glucose metabolism in sporadic Alzheimer disease: therapeutic implications. Adv Exp Med Biol (2004) 1.29
Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme. Antioxid Redox Signal (2005) 1.28
High glucose inhibits glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells. J Biol Chem (2000) 1.28
Uncoupling protein-2 participates in cellular defense against oxidative stress in clonal beta-cells. Biochem Biophys Res Commun (2001) 1.24
Protection in the aged heart: preventing the heart-break of old age? Cardiovasc Res (2005) 1.23
Diabetes mellitus and Alzheimer's disease: shared pathology and treatment? Br J Clin Pharmacol (2011) 1.22
Pathophysiology of oxidative stress in diabetes mellitus. J Diabetes Complications (2001) 1.21
Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis. FEBS Lett (1993) 1.19
Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation. Diabetes (2002) 1.17
The role of vitamin E and oxidative stress in diabetes complications. Mech Ageing Dev (2010) 1.17
RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol (2009) 1.15
Impacts of oxidative stress and antioxidants on semen functions. Vet Med Int (2010) 1.12
Reactive oxygen species: the unavoidable environmental insult? Mutat Res (1999) 1.12
Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death. PLoS One (2012) 1.12
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis (2013) 1.11
Free radicals: properties, sources, targets, and their implication in various diseases. Indian J Clin Biochem (2014) 1.11
Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease. Curr Pharm Des (2008) 1.10
The receptor for advanced glycation end products is highly expressed in the skin and upregulated by advanced glycation end products and tumor necrosis factor-alpha. J Invest Dermatol (2006) 1.09
Vascular dysfunction of venous bypass conduits is mediated by reactive oxygen species in diabetes: role of endothelin-1. J Pharmacol Exp Ther (2004) 1.03
Cell degeneration induced by amyloid-beta peptides: implications for Alzheimer's disease. J Mol Neurosci (2004) 1.01
Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain. Biochim Biophys Acta (2014) 1.01
Positive oxidative stress in aging and aging-related disease tolerance. Redox Biol (2014) 1.01
Free radical-mediated lung response to the monofunctional sulfur mustard butyl 2-chloroethyl sulfide after subcutaneous injection. Toxicology (1992) 0.98
Reduced plasma peroxyl radical trapping capacity and increased susceptibility of LDL to oxidation in poorly controlled IDDM. Diabetes (1994) 0.98
The glutamatergic system and Alzheimer's disease: therapeutic implications. CNS Drugs (2003) 0.97
A molecular description of cellulose biosynthesis. Annu Rev Biochem (2015) 0.97
Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies. Drugs Aging (2010) 0.95
A review of types 1 and 2 diabetes mellitus and their treatment with insulin. Am J Ther (2006) 0.93
Association of ATP synthase alpha-chain with neurofibrillary degeneration in Alzheimer's disease. Neuroscience (2003) 0.92
The hexosamine pathway regulates the plasminogen activator inhibitor-1 gene promoter and Sp1 transcriptional activation through protein kinase C-beta I and -delta. J Biol Chem (2002) 0.92
Diabetes mellitus and oxidative stress-A concise review. Saudi Pharm J (2015) 0.90
Nutrient regulation of insulin secretion and action. J Endocrinol (2014) 0.90