Published in Biochem J on January 15, 1988
The properties of the ATP-induced depolarization and current in single cells isolated from the guinea-pig urinary bladder. Br J Pharmacol (1990) 1.74
Understanding the GABAA receptor: a chemically gated ion channel. Biochem J (1988) 1.04
Different types of glutamate receptors in isolated and identified neurones of the mollusc Planorbarius corneus. J Physiol (1991) 0.97
Role of dopaminergic and adrenergic receptors in the pathogenesis of arterial lesions induced by fenoldopam mesylate and dopamine in the rat. Am J Pathol (1989) 0.92
Acetylcholine induces voltage-independent increase of cytosolic calcium in mouse myotubes. Proc Natl Acad Sci U S A (1991) 0.87
Purification of brain D2 dopamine receptor. EMBO J (1988) 0.80
Molecular size of the 5-HT3 receptor solubilized from NCB 20 cells. Biochem J (1990) 0.79
Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature (1984) 25.71
Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. Nature (1986) 7.06
Excitatory amino acid transmitters. Annu Rev Pharmacol Toxicol (1981) 6.70
Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain. J Biol Chem (1984) 6.58
Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family. Nature (1987) 5.12
Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor. Nature (1986) 4.97
GTP-binding proteins couple cardiac muscarinic receptors to a K channel. Nature (1985) 4.95
Structural homology of Torpedo californica acetylcholine receptor subunits. Nature (1983) 4.70
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. Proc Natl Acad Sci U S A (1987) 4.61
Alzheimer's disease: a disorder of cortical cholinergic innervation. Science (1983) 4.40
The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors. Nature (1987) 4.15
Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells. Pflugers Arch (1984) 4.11
Primary structure of alpha-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence. Nature (1982) 3.69
The long and the short of long-term memory--a molecular framework. Nature (1986) 3.68
Uncoupling of cardiac muscarinic and beta-adrenergic receptors from ion channels by a guanine nucleotide analogue. Nature (1985) 3.44
Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production. Nature (1986) 3.41
Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart. Nature (1983) 3.34
The GTP-binding protein, Go, regulates neuronal calcium channels. Nature (1987) 3.24
A G protein couples serotonin and GABAB receptors to the same channels in hippocampus. Science (1986) 3.17
Primary structure and biochemical properties of an M2 muscarinic receptor. Science (1987) 3.16
GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels. Nature (1986) 3.01
A family of receptors coupled to guanine nucleotide regulatory proteins. Biochemistry (1987) 2.91
On the mechanism of activation of muscarinic K+ channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins. Pflugers Arch (1986) 2.81
The nicotinic cholinergic receptor: correlation of molecular structure with functional properties. Annu Rev Biochem (1982) 2.67
Primary structures of beta- and delta-subunit precursors of Torpedo californica acetylcholine receptor deduced from cDNA sequences. Nature (1983) 2.55
Central catecholamine neuron systems: anatomy and physiology of the norepinephrine and epinephrine systems. Annu Rev Neurosci (1979) 2.51
Direct activation of mammalian atrial muscarinic potassium channels by GTP regulatory protein Gk. Science (1987) 2.50
The avian beta-adrenergic receptor: primary structure and membrane topology. Proc Natl Acad Sci U S A (1986) 2.45
Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells. Proc Natl Acad Sci U S A (1986) 2.45
Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization. Nature (1986) 2.35
Inositol phospholipid hydrolysis in rat cerebral cortical slices: I. Receptor characterisation. J Neurochem (1984) 2.26
Receptor interactions in a signalling system: competition between ribose receptor and galactose receptor in the chemotaxis response. Proc Natl Acad Sci U S A (1976) 2.17
Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation. Nature (1987) 2.16
A new type of glutamate receptor linked to inositol phospholipid metabolism. Nature (1987) 2.15
Purification by affinity chromatography of the glycine receptor of rat spinal cord. J Biol Chem (1982) 2.06
Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence. FEBS Lett (1986) 2.03
The beta-adrenergic receptor and adenylate cyclase. Biochim Biophys Acta (1976) 2.02
Glutamate stimulates inositol phosphate formation in striatal neurones. Nature (1985) 2.02
On the mechanism of muscarinic inhibition of the cardiac Ca current. Pflugers Arch (1986) 1.95
Presynaptic receptors. Annu Rev Pharmacol Toxicol (1981) 1.91
GABA-benzodiazepine-barbiturate receptor interactions. J Neurochem (1981) 1.75
Inhibition of motoneurones by iontophoresis of glycine. Nature (1967) 1.65
Substance P as a transmitter candidate. Annu Rev Neurosci (1980) 1.64
A guanine nucleotide-binding protein mediates the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line. Proc Natl Acad Sci U S A (1986) 1.62
Guanine nucleotide-binding regulatory proteins and dual control of adenylate cyclase. J Clin Invest (1984) 1.60
Protein phosphorylation in the brain. Nature (1983) 1.60
Molecular regulators of brain function: a new view. Neuroscience (1984) 1.58
GTP-binding proteins. One molecular machine can transduce diverse signals. Nature (1986) 1.56
Two polyphosphatidylinositide metabolites control two K+ currents in a neuronal cell. Nature (1986) 1.56
Central catecholamine neuron systems: anatomy and physiology of the dopamine systems. Annu Rev Neurosci (1978) 1.56
Mechanisms of slow postsynaptic potentials. Nature (1981) 1.54
Amino acid neurotransmitters and their pathways in the mammalian central nervous system. Neuroscience (1983) 1.47
The GTP-binding regulatory proteins of neuroblastoma x glioma, NG108-15, and glioma, C6, cells. Immunochemical evidence of a pertussis toxin substrate that is neither Ni nor No. FEBS Lett (1986) 1.45
Presynaptic regulation of neurotransmitter release in the brain: facts and hypothesis. Neuroscience (1984) 1.39
Phenobarbitone modulation of postsynaptic GABA receptor function on cultured mammalian neurons. Proc R Soc Lond B Biol Sci (1979) 1.35
Go, a guanine nucleotide-binding protein: immunohistochemical localization in rat brain resembles distribution of second messenger systems. Proc Natl Acad Sci U S A (1986) 1.35
Immunocytochemical localization of choline acetyltransferase in rat cerebral cortex: a study of cholinergic neurons and synapses. J Comp Neurol (1985) 1.35
Regulation of calcium currents by a GTP analogue: potentiation of (-)-baclofen-mediated inhibition. Neurosci Lett (1986) 1.34
gamma-aminobutyric acid B receptors are negatively coupled to adenylate cyclase in brain, and in the cerebellum these receptors may be associated with granule cells. Mol Pharmacol (1984) 1.29
A new GTP-binding protein in brain tissues serving as the specific substrate of islet-activating protein, pertussis toxin. FEBS Lett (1987) 1.27
Coupling of inositol phospholipid metabolism with excitatory amino acid recognition sites in rat hippocampus. J Neurochem (1986) 1.26
Serotonin nerve terminals in adult rat neocortex. Brain Res (1975) 1.23
Correlation between senile plaque and neurofibrillary tangle counts in cerebral cortex and neuronal counts in cortex and subcortical structures in Alzheimer's disease. Neurosci Lett (1985) 1.22
Mammalian beta 1- and beta 2-adrenergic receptors. Immunological and structural comparisons. J Biol Chem (1986) 1.20
The monoamine innervation of rat cerebral cortex: synaptic and nonsynaptic axon terminals. Neuroscience (1978) 1.19
Studies of the uptake of 3 H-gaba and ( 3 H)glycine in slices and homogenates of rat brain and spinal cord by electron microscopic autoradiography. Brain Res (1972) 1.18
Cloning and sequence analysis of the human brain beta-adrenergic receptor. Evolutionary relationship to rodent and avian beta-receptors and porcine muscarinic receptors. FEBS Lett (1987) 1.18
Alpha 1-adrenergic receptor-mediated phosphoinositide hydrolysis and prostaglandin E2 formation in Madin-Darby canine kidney cells. Possible parallel activation of phospholipase C and phospholipase A2. J Biol Chem (1987) 1.15
Excitatory amino acids inhibit stimulation of phosphatidylinositol metabolism by aminergic agonists in hippocampus. Nature (1986) 1.14
Positron emission tomography after MPTP: observations relating to the cause of Parkinson's disease. Nature (1985) 1.14
Detection of the major pertussis toxin substrate of human leukocytes with antisera raised against synthetic peptides. FEBS Lett (1986) 1.12
Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS. Nature (1984) 1.09
Quantification of the dopamine innervation in adult rat neostriatum. Neuroscience (1986) 1.08
Molecular distinction between muscarinic acetylcholine receptor subtypes. Nature (1987) 1.07
Alpha-bungarotoxin binding and central nervous system nicotinic acetylcholine receptors. Neuroscience (1981) 1.07
Identification and properties of N-methyl-D-aspartate receptors in rat brain synaptic plasma membranes. Proc Natl Acad Sci U S A (1986) 1.06
Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h. Proc Natl Acad Sci U S A (1986) 1.05
Astrocyte glutamate receptor activation promotes inositol phospholipid turnover and calcium flux. Neurosci Lett (1986) 1.02
Purification of the opiate receptor of NG108-15 neuroblastoma-glioma hybrid cells. Proc Natl Acad Sci U S A (1985) 1.02
The endorphins: a growing family of pharmacologically pertinent peptides. Annu Rev Pharmacol Toxicol (1983) 1.01
Individual cells in the nucleus basalis--diagonal band complex have restricted axonal projections to the cerebral cortex in the rat. Brain Res (1983) 1.01
Purification of the muscarinic acetylcholine receptor from porcine atria. Proc Natl Acad Sci U S A (1984) 1.00
Mechanism of guanine nucleotide regulatory protein-mediated inhibition of adenylate cyclase. Studies with isolated subunits of transducin in a reconstituted system. J Biol Chem (1986) 0.99
Photoaffinity labeling of the D2-dopamine receptor using a novel high affinity radioiodinated probe. J Biol Chem (1985) 0.99
The Ferrier Lecture, 1983. Amino acids and peptides: fast and slow chemical signals in the nervous system? Proc R Soc Lond B Biol Sci (1984) 0.98
Electron microscopic autoradiographic localization of opioid receptors in rat neostriatum. Nature (1984) 0.98
Purification of an active opioid-binding protein from bovine striatum. J Biol Chem (1985) 0.97
Inhibition of GABAB receptor binding by guanyl nucleotides. J Neurochem (1984) 0.96
Covalent labeling of opioid receptors with radioiodinated human beta-endorphin. Identification of binding site subunit. J Biol Chem (1985) 0.96
Purification and characterization of the human platelet alpha 2-adrenergic receptor. J Biol Chem (1986) 0.96
Mammalian alpha 1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit. J Biol Chem (1986) 0.94
G-protein control of inositol phosphate hydrolysis. Nature (1986) 0.93
Islet activating protein inhibits physiological responses evoked by cardiac muscarinic acetylcholine receptors. Role of guanosine triphosphate binding proteins in regulation of potassium permeability. Biochemistry (1985) 0.92
Predicting Parkinson's disease. Nature (1985) 0.91
Purification to apparent homogeneity of a mu-type opioid receptor from rat brain. Proc Natl Acad Sci U S A (1986) 0.91
Gonadotropin-releasing hormone activates a rapid Ca2+-independent phosphodiester hydrolysis of polyphosphoinositides in pituitary gonadotrophs. J Biol Chem (1986) 0.90