Published in Pediatr Infect Dis J on September 20, 2017
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TLR3 deficiency in patients with herpes simplex encephalitis. Science (2007) 5.86
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Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med (2003) 3.89
Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells. J Exp Med (2008) 3.85
Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome. Nat Genet (2010) 3.60
Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med (2007) 2.85
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Terminally differentiated CD8⁺ T cells negatively affect bone regeneration in humans. Sci Transl Med (2013) 2.43
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Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity. Blood (2010) 2.32
Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine (Baltimore) (2010) 2.26
X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production. J Exp Med (2006) 2.18
Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses. Immunity (2005) 2.16
Variants in CPA1 are strongly associated with early onset chronic pancreatitis. Nat Genet (2013) 2.10
Diagnostic approach to microcephaly in childhood: a two-center study and review of the literature. Dev Med Child Neurol (2014) 1.95
Impact of CYP2C9 and CYP2C19 polymorphisms on tolbutamide kinetics and the insulin and glucose response in healthy volunteers. Pharmacogenetics (2002) 1.85
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. Immunity (2008) 1.83
CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated? Gut (2012) 1.77
Naturally occurring anti-IFN-gamma autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans. Blood (2003) 1.76
Monitoring temporary immunodepression by flow cytometric measurement of monocytic HLA-DR expression: a multicenter standardized study. Clin Chem (2005) 1.74
Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene. Clin Pharmacol Ther (2002) 1.58
From idiopathic infectious diseases to novel primary immunodeficiencies. J Allergy Clin Immunol (2005) 1.54
Human Toll-like receptor-dependent induction of interferons in protective immunity to viruses. Immunol Rev (2007) 1.47
Cellular immunodepression preceding infectious complications after acute ischemic stroke in humans. Cerebrovasc Dis (2007) 1.42
Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers. Clin Pharmacol Ther (2002) 1.42
Stroke propagates bacterial aspiration to pneumonia in a model of cerebral ischemia. Stroke (2006) 1.39
Hematologic effects of maternal antiretroviral therapy and transmission prophylaxis in HIV-1-exposed uninfected newborn infants. J Acquir Immune Defic Syndr (2007) 1.34
IRAK4 and NEMO mutations in otherwise healthy children with recurrent invasive pneumococcal disease. J Med Genet (2006) 1.30
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Standardization of whole blood immune phenotype monitoring for clinical trials: panels and methods from the ONE study. Transplant Res (2013) 1.27
No evidence for XMRV in German CFS and MS patients with fatigue despite the ability of the virus to infect human blood cells in vitro. PLoS One (2010) 1.25
The NEMO mutation creating the most-upstream premature stop codon is hypomorphic because of a reinitiation of translation. Am J Hum Genet (2006) 1.24
Nuclear factor kappaB essential modulator-deficient child with immunodeficiency yet without anhidrotic ectodermal dysplasia. J Allergy Clin Immunol (2004) 1.17
Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis. Crit Care (2009) 1.16
Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation. Proc Natl Acad Sci U S A (2011) 1.15
Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE. J Mol Med (Berl) (2008) 1.14
Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO. J Cereb Blood Flow Metab (2012) 1.11
Immune responses after acute ischemic stroke or myocardial infarction. Int J Cardiol (2010) 1.08
The development of childhood asthma: lessons from the German Multicentre Allergy Study (MAS). Paediatr Respir Rev (2002) 1.07
Diagnostic approach to the hyper-IgE syndromes: immunologic and clinical key findings to differentiate hyper-IgE syndromes from atopic dermatitis. J Allergy Clin Immunol (2010) 1.03
Shigella sonnei meningitis due to interleukin-1 receptor-associated kinase-4 deficiency: first association with a primary immune deficiency. Clin Infect Dis (2005) 1.03
Heme oxygenase-1 inhibits T cell-dependent skin inflammation and differentiation and function of antigen-presenting cells. Exp Dermatol (2007) 1.02
Influence of stroke localization on autonomic activation, immunodepression, and post-stroke infection. Cerebrovasc Dis (2011) 1.01
Sustained BK viruria as an early marker for the development of BKV-associated nephropathy: analysis of 4128 urine and serum samples. Transplantation (2009) 1.01
Human peripheral blood and bone marrow Epstein-Barr virus-specific T-cell repertoire in latent infection reveals distinct memory T-cell subsets. Eur J Immunol (2010) 1.01
Bronchoalveoloar lavage fluid cytokines and chemokines as markers and predictors for the outcome of interstitial lung disease in systemic sclerosis patients. Arthritis Res Ther (2009) 1.01
MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males. Br J Clin Pharmacol (2002) 0.99
Influence of CYP2C9 and CYP2D6 polymorphisms on the pharmacokinetics of nateglinide in genotyped healthy volunteers. Clin Pharmacokinet (2004) 0.99
Standardized immune monitoring for the prediction of infections after cardiopulmonary bypass surgery in risk patients. Cytometry B Clin Cytom (2003) 0.99
The role of adaptor proteins in lymphocyte activation. Mol Immunol (2004) 0.99
Impact of the ultrarapid metabolizer genotype of cytochrome P450 2D6 on metoprolol pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther (2004) 0.99
CCN1: a novel inflammation-regulated biphasic immune cell migration modulator. Cell Mol Life Sci (2012) 0.98
History of respiratory infections in the first 12 yr among children from a birth cohort. Pediatr Allergy Immunol (2007) 0.97
Immunodepression after aneurysmal subarachnoid hemorrhage. Stroke (2010) 0.96
Autosomal recessive interleukin-1 receptor-associated kinase 4 deficiency in fourth-degree relatives. J Pediatr (2006) 0.95
Different modes of IL-10 and TGF-beta to inhibit cytokine-dependent IFN-gamma production: consequences for reversal of lipopolysaccharide desensitization. J Immunol (2003) 0.95
Pandemic influenza A (H1N1) outbreak among 15 school-aged HIV-1-infected children. Clin Infect Dis (2010) 0.95
From infectious diseases to primary immunodeficiencies. Immunol Allergy Clin North Am (2008) 0.94
Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites. Pharmacogenetics (2003) 0.94
Fatal intracerebral mass bleeding associated with Ginkgo biloba and ibuprofen. Atherosclerosis (2003) 0.93
Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways. J Cell Sci (2011) 0.92
The transmembrane adapter protein SIT regulates thymic development and peripheral T-cell functions. Mol Cell Biol (2005) 0.92
Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol-lowering activity of (-)-3S,5R-fluvastatin and (+)-3R,5S-fluvastatin in healthy volunteers. Clin Pharmacol Ther (2003) 0.90
Protection from brain damage and bacterial infection in murine stroke by the novel caspase-inhibitor Q-VD-OPH. Exp Neurol (2007) 0.89
Analyses of phenotypic and functional characteristics of CX3CR1-expressing natural killer cells. Immunology (2011) 0.89
Nonsteroidal antiinflammatory drugs and a selective cyclooxygenase 2 inhibitor uncouple mitochondria in intact cells. Arthritis Rheum (2003) 0.88
Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2. Clin Pharmacol Ther (2002) 0.88
Association of MDR1 genotypes with susceptibility to colorectal cancer in older non-smokers. Eur J Clin Pharmacol (2006) 0.87
The SCIentinel study--prospective multicenter study to define the spinal cord injury-induced immune depression syndrome (SCI-IDS)--study protocol and interim feasibility data. BMC Neurol (2013) 0.86
Mouse strains differ in their susceptibility to poststroke infections. Neuroimmunomodulation (2006) 0.86
Inherited human IRAK-4 deficiency: an update. Immunol Res (2007) 0.86
Immunoglobulin replacement therapy in primary antibody deficiency diseases--maximizing success. Int Arch Allergy Immunol (2005) 0.86
Assessment of monocytic HLA-DR expression in ICU patients: analytical issues for multicentric flow cytometry studies. Crit Care (2010) 0.85
Predicting post-stroke infections and outcome with blood-based immune and stress markers. Cerebrovasc Dis (2012) 0.85
Elevation of CD4+ differentiated memory T cells is associated with acute cellular and antibody-mediated rejection after liver transplantation. Transplantation (2013) 0.85
Successful unrelated bone marrow transplantation in a child with chronic granulomatous disease complicated by pulmonary and cerebral granuloma formation. Eur J Pediatr (2006) 0.85
Differential affection of intestinal immune cell populations after cerebral ischemia in mice. Neuroimmunomodulation (2009) 0.85
Superiority of preventive antibiotic treatment compared with standard treatment of poststroke pneumonia in experimental stroke: a bed to bench approach. J Cereb Blood Flow Metab (2013) 0.84
CD31+ naïve Th cells are stable during six months following kidney transplantation: implications for post-transplant thymic function. Am J Transplant (2005) 0.84
Benefit assessment of preventive medical check-ups in patients suffering from chronic granulomatous disease (CGD). J Eval Clin Pract (2005) 0.83
Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock. Scand J Infect Dis (2010) 0.83
Transient suppression of atopy in early childhood is associated with high vaccination coverage. Pediatrics (2003) 0.83
Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans. Br J Clin Pharmacol (2003) 0.82
Staphylococcal pericarditis, and liver and paratracheal abscesses as presentations in two new cases of interleukin-1 receptor associated kinase 4 deficiency. Pediatr Infect Dis J (2008) 0.82
Microglial activation milieu controls regulatory T cell responses. J Immunol (2013) 0.81
Pharmacogenetics-based new therapeutic concepts. Drug Metab Rev (2004) 0.81
Effects of CYP2C9 polymorphisms on the pharmacokinetics of R- and S-phenprocoumon in healthy volunteers. Pharmacogenetics (2004) 0.81
Association of TLR3-hyporesponsiveness and functional TLR3 L412F polymorphism with recurrent herpes labialis. Hum Immunol (2012) 0.81
Polymorphisms of adrenergic receptors and the risk of heart failure. N Engl J Med (2003) 0.81
Alpha-MSH promotes spontaneous post-ischemic pneumonia in mice via melanocortin-receptor-1. Exp Neurol (2008) 0.80
Differential expression and function of α-mannosidase I in stimulated naive and memory CD4+ T cells. J Immunother (2011) 0.80
Clinical manifestation of mannose-binding lectin deficiency in adults independent of concomitant immunodeficiency. Hum Immunol (2009) 0.80
Miniaturized bronchoscopy enables unilateral investigation, application, and sampling in mice. Am J Respir Cell Mol Biol (2014) 0.80