Published in Nat Commun on October 10, 2017
Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation (1986) 19.82
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand. Proc Natl Acad Sci U S A (2007) 7.96
MAPK cascade signalling and synaptic plasticity. Nat Rev Neurosci (2004) 5.95
Chronic back pain is associated with decreased prefrontal and thalamic gray matter density. J Neurosci (2004) 4.05
MAP kinase and pain. Brain Res Rev (2008) 3.75
Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion. Circulation (1993) 3.68
The epidemiology of chronic pain of predominantly neuropathic origin. Results from a general population survey. J Pain (2006) 3.67
Myocardial protection by brief ischemia in noncardiac tissue. Circulation (1996) 2.91
Myocardial ischemia-reperfusion injury: a neglected therapeutic target. J Clin Invest (2013) 2.83
Towards a theory of chronic pain. Prog Neurobiol (2008) 2.76
Chronic spinal pain and physical-mental comorbidity in the United States: results from the national comorbidity survey replication. Pain (2005) 2.50
Prodromal angina limits infarct size. A role for ischemic preconditioning. Circulation (1995) 2.46
Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis. J Pain (2003) 2.09
An investigation of association between chronic musculoskeletal pain and cardiovascular disease in the Health Survey for England (2008). Eur J Pain (2013) 2.01
Trends in hospitalizations and outcomes for acute cardiovascular disease and stroke, 1999-2011. Circulation (2014) 1.90
Peripheral nociception associated with surgical incision elicits remote nonischemic cardioprotection via neurogenic activation of protein kinase C signaling. Circulation (2009) 1.86
Pain as a global public health priority. BMC Public Health (2011) 1.82
Different pain, different brain: thalamic anatomy in neuropathic and non-neuropathic chronic pain syndromes. J Neurosci (2011) 1.82
Remote ischaemic pre- and delayed postconditioning - similar degree of cardioprotection but distinct mechanisms. Exp Physiol (2012) 1.80
Activation of the extracellular signal-regulated kinase in the amygdala modulates pain perception. J Neurosci (2007) 1.67
Remote ischemic conditioning. J Am Coll Cardiol (2015) 1.66
Apoptosis in myocardial ischaemia and infarction. J Clin Pathol (2002) 1.59
Efferent projections of the paraventricular thalamic nucleus in the rat. J Comp Neurol (1995) 1.57
Projections of the paraventricular and paratenial nuclei of the dorsal midline thalamus in the rat. J Comp Neurol (2008) 1.56
When does acute pain become chronic? Br J Anaesth (2010) 1.48
Interaction of risk factors, comorbidities, and comedications with ischemia/reperfusion injury and cardioprotection by preconditioning, postconditioning, and remote conditioning. Pharmacol Rev (2014) 1.47
Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats. Eur J Pain (2008) 1.47
Prodromal angina is associated with myocardial salvage in acute ST-segment elevation myocardial infarction. Eur Heart J Cardiovasc Imaging (2013) 1.45
Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial K(ATP) channels. Circ Res (2001) 1.43
What is this thing called pain? J Clin Invest (2010) 1.37
The Ca(v)3.2 T-type Ca(2+) channel is required for pressure overload-induced cardiac hypertrophy in mice. Circ Res (2009) 1.34
Remote preconditioning protects the heart by activating myocardial PKCepsilon-isoform. Cardiovasc Res (2002) 1.31
Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones. Cardiovasc Res (2012) 1.23
TNF-alpha is required for late ischemic preconditioning but not for remote preconditioning of trauma. J Surg Res (2004) 1.20
Vagal nerve stimulation prevents reperfusion injury through inhibition of opening of mitochondrial permeability transition pore independent of the bradycardiac effect. J Thorac Cardiovasc Surg (2009) 1.20
Refined approach for quantification of in vivo ischemia-reperfusion injury in the mouse heart. Am J Physiol Heart Circ Physiol (2009) 1.17
Global and Regional Patterns in Cardiovascular Mortality From 1990 to 2013. Circulation (2015) 1.17
Role of the parasympathetic nervous system in cardioprotection by remote hindlimb ischaemic preconditioning. Exp Physiol (2012) 1.11
Projections of the bed nucleus of the stria terminalis to the mesencephalon, pons, and medulla oblongata in the cat. Exp Brain Res (1985) 1.10
Preconditioning with PKC and the ATP-sensitive potassium channels: a codependent relationship. Ann Thorac Surg (2000) 1.08
Paraventricular thalamic nucleus: subcortical connections and innervation by serotonin, orexin, and corticotropin-releasing hormone in macaque monkeys. J Comp Neurol (2009) 1.05
Neuropeptide neuronal efferents from the bed nucleus of the stria terminalis and central amygdaloid nucleus to the dorsal vagal complex in the rat. J Comp Neurol (1987) 1.01
Preinfarction angina protects against out-of-hospital ventricular fibrillation in patients with acute occlusion of the left coronary artery. J Am Coll Cardiol (2001) 0.98
Comorbidity of low back pain: representative outcomes of a national health study in the Federal Republic of Germany. Eur J Pain (2006) 0.98
Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain. J Neurosci (2010) 0.97
Remote cardioprotection by direct peripheral nerve stimulation and topical capsaicin is mediated by circulating humoral factors. Basic Res Cardiol (2012) 0.96
Preinfarction angina reduces infarct size in ST-elevation myocardial infarction treated with percutaneous coronary intervention. Circ Cardiovasc Interv (2013) 0.92
Contributions of the paraventricular thalamic nucleus in the regulation of stress, motivation, and mood. Front Behav Neurosci (2014) 0.91
Transcutaneous electrical nerve stimulation as a novel method of remote preconditioning: in vitro validation in an animal model and first human observations. Basic Res Cardiol (2014) 0.90
Influence of pre-infarction angina, collateral flow, and pre-procedural TIMI flow on myocardial salvage index by cardiac magnetic resonance in patients with ST-segment elevation myocardial infarction. Eur Heart J Cardiovasc Imaging (2011) 0.88
Reperfusion kinase phosphorylation is essential but not sufficient in the mediation of pharmacological preconditioning: Characterisation in the bi-phasic profile of early and late protection. Cardiovasc Res (2006) 0.88
Vagus nerve stimulation initiated late during ischemia, but not reperfusion, exerts cardioprotection via amelioration of cardiac mitochondrial dysfunction. Heart Rhythm (2014) 0.87
Cortical reorganization in primary somatosensory cortex in patients with unilateral chronic pain. J Pain (2009) 0.87
Co-dependence of the neural and humoral pathways in the mechanism of remote ischemic conditioning. Basic Res Cardiol (2016) 0.86
Acute, delayed and chronic remote ischemic conditioning is associated with downregulation of mTOR and enhanced autophagy signaling. PLoS One (2014) 0.84
KATP channels in rat heart: blockade of ischemic and acetylcholine-mediated preconditioning by glibenclamide. Am J Physiol (1996) 0.84
Acetylcholine attenuates hypoxia/ reoxygenation-induced mitochondrial and cytosolic ROS formation in H9c2 cells via M2 acetylcholine receptor. Cell Physiol Biochem (2013) 0.83
Chronic musculoskeletal pain predicted hospitalisation due to serious medical conditions in a 10 year follow up study. BMC Musculoskelet Disord (2010) 0.82
Activation of cardiac muscarinic receptor and ischemic preconditioning effects in in situ rat heart. Heart Vessels (1997) 0.82
Neural mechanisms of cardioprotection. Physiology (Bethesda) (2014) 0.82
Detection of endogenous acetylcholine release during brief ischemia in the rabbit ventricle: a possible trigger for ischemic preconditioning. Life Sci (2009) 0.82
Identifying the Source of a Humoral Factor of Remote (Pre)Conditioning Cardioprotection. PLoS One (2016) 0.79
Targeting P(2)X(7) receptor for the treatment of central post-stroke pain in a rodent model. Neurobiol Dis (2015) 0.78
Bed nucleus of the stria terminalis alpha(1)-adrenoceptor modulates baroreflex cardiac component in unanesthetized rats. Brain Res (2008) 0.77
Is Chronic Low Back Pain Associated with the Prevalence of Coronary Heart Disease when Genetic Susceptibility Is Considered? A Co-Twin Control Study of Spanish Twins. PLoS One (2016) 0.75