PubRank

W J Welch

Author PubWeight™ 194.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly. Science 1990 5.88
2 Uncoating ATPase is a member of the 70 kilodalton family of stress proteins. Cell 1986 4.98
3 Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides. Mol Cell Biol 1985 4.75
4 Role of the major heat shock proteins as molecular chaperones. Annu Rev Cell Biol 1993 4.51
5 Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells. J Biol Chem 1984 4.20
6 Cellular and biochemical events in mammalian cells during and after recovery from physiological stress. J Cell Biol 1986 3.18
7 Vesicular stomatitis virus glycoprotein is anchored in the viral membrane by a hydrophobic domain near the COOH terminus. Proc Natl Acad Sci U S A 1980 2.87
8 Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein. Cell Stress Chaperones 1996 2.80
9 Purification of the major mammalian heat shock proteins. J Biol Chem 1982 2.79
10 Biochemical characterization of the mammalian stress proteins and identification of two stress proteins as glucose- and Ca2+-ionophore-regulated proteins. J Biol Chem 1983 2.78
11 ATP-induced protein-Hsp70 complex dissociation requires K+ but not ATP hydrolysis. Nature 1993 2.77
12 Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase. J Cell Biol 1988 2.72
13 Heat shock is lethal to fibroblasts microinjected with antibodies against hsp70. Science 1988 2.51
14 The common 90-kd protein component of non-transformed '8S' steroid receptors is a heat-shock protein. EMBO J 1985 2.50
15 Interaction of hsp70 with unfolded proteins: effects of temperature and nucleotides on the kinetics of binding. Proc Natl Acad Sci U S A 1991 2.41
16 Mutant p53 proteins bind hsp 72/73 cellular heat shock-related proteins in SV40-transformed monkey cells. Oncogene 1987 2.32
17 STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. VI. THE PHYSIOLOGICAL DISPOSITION, ANTIMALARIAL ACTIVITY, AND TOXICITY OF SEVERAL DERIVATIVES OF 4-AMINOQUINOLINE. J Clin Invest 1948 2.31
18 Recognition by human V gamma 9/V delta 2 T cells of a GroEL homolog on Daudi Burkitt's lymphoma cells. Science 1990 2.25
19 Dynamic changes in the structure and intracellular locale of the mammalian low-molecular-weight heat shock protein. Mol Cell Biol 1988 2.21
20 Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment. J Cell Biol 1985 2.18
21 Molecular and cellular effects of heat-shock and related treatments of mammalian tissue-culture cells. Cold Spring Harb Symp Quant Biol 1982 2.18
22 Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome). Nature 1988 2.15
23 Heat shock gene regulation by nascent polypeptides and denatured proteins: hsp70 as a potential autoregulatory factor. J Cell Biol 1992 2.10
24 Phorbol ester, calcium ionophore, or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000-dalton mammalian stress proteins. J Biol Chem 1985 1.97
25 Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications. J Natl Cancer Inst 1993 1.95
26 Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci U S A 1992 1.93
27 Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic: role of nitric oxide. Hypertension 1998 1.92
28 Characterization of the thermotolerant cell. I. Effects on protein synthesis activity and the regulation of heat-shock protein 70 expression. J Cell Biol 1988 1.87
29 Chemical chaperones interfere with the formation of scrapie prion protein. EMBO J 1996 1.81
30 Two small virus-specific polypeptides are produced during infection with Sindbis virus. J Virol 1979 1.79
31 STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. VII. THE ANTIMALARIAL ACTIVITY OF PAMAQUINE. J Clin Invest 1948 1.74
32 Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins. J Cell Biol 1999 1.72
33 Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events. J Biol Chem 1992 1.65
34 Characterization and purification of the small 28,000-dalton mammalian heat shock protein. J Biol Chem 1987 1.63
35 Correcting temperature-sensitive protein folding defects. J Clin Invest 1997 1.61
36 Intrarenal vasoconstriction during hyperchloremia: role of thromboxane. Am J Physiol 1989 1.60
37 Heat shock protein induction in rat hearts. A role for improved myocardial salvage after ischemia and reperfusion? Circulation 1992 1.57
38 Examining the function and regulation of hsp 70 in cells subjected to metabolic stress. J Cell Biol 1992 1.55
39 Autoantibodies to the constitutive 73-kD member of the hsp70 family of heat shock proteins in systemic lupus erythematosus. J Exp Med 1988 1.54
40 Hyperthermia protects against light damage in the rat retina. Science 1988 1.52
41 Clinical implications of the stress response. J Clin Invest 1995 1.51
42 A eukaryotic cytosolic chaperonin is associated with a high molecular weight intermediate in the assembly of hepatitis B virus capsid, a multimeric particle. J Cell Biol 1994 1.51
43 Identification, characterization, and purification of two mammalian stress proteins present in mitochondria, grp 75, a member of the hsp 70 family and hsp 58, a homolog of the bacterial groEL protein. J Biol Chem 1989 1.47
44 Localization of 70-kDa stress protein induction in gerbil brain after ischemia. Acta Neuropathol 1988 1.47
45 Medium tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with 73-kilodalton heat shock protein. J Virol 1987 1.43
46 Expression of heat shock proteins in Alzheimer's disease. Neurology 1991 1.35
47 Involvement of 70-kD heat-shock proteins in peroxisomal import. J Cell Biol 1994 1.34
48 Mitogen and lymphokine stimulation of heat shock proteins in T lymphocytes. Proc Natl Acad Sci U S A 1988 1.31
49 Complexes between nascent polypeptides and their molecular chaperones in the cytosol of mammalian cells. Mol Biol Cell 1997 1.30
50 Autoantibodies to human stress proteins. A survey of various rheumatic and other inflammatory diseases. Arthritis Rheum 1991 1.30
51 Response of human breast cancer cells to heat shock and chemotherapeutic drugs. Cancer Res 1992 1.30
52 The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR. Proc Natl Acad Sci U S A 1997 1.29
53 Binding of heat shock proteins to the avian progesterone receptor. Mol Cell Biol 1989 1.29
54 Colocalization of demethylating enzymes and NOS and functional effects of methylarginines in rat kidney. Kidney Int 1997 1.28
55 Natriuretic and diuretic actions of a highly selective adenosine A1 receptor antagonist. J Am Soc Nephrol 1999 1.28
56 Modulation of vimentin containing intermediate filament distribution and phosphorylation in living fibroblasts by the cAMP-dependent protein kinase. J Cell Biol 1989 1.28
57 Both viral (adenovirus E1B) and cellular (hsp 70, p53) components interact with centrosomes. J Cell Physiol 1994 1.27
58 Cell cycle-dependent association of HSP70 with specific cellular proteins. J Cell Biol 1989 1.25
59 Complex environment of nascent polypeptide chains. J Biol Chem 1994 1.22
60 Molecular chaperones and the centrosome. A role for TCP-1 in microtubule nucleation. J Biol Chem 1996 1.21
61 Scrapie prions selectively modify the stress response in neuroblastoma cells. Proc Natl Acad Sci U S A 1995 1.21
62 Possible involvement of the 90-kDa heat shock protein in the regulation of protein synthesis. J Biol Chem 1989 1.13
63 TGF and nitric oxide: effects of salt intake and salt-sensitive hypertension. Kidney Int Suppl 1996 1.13
64 STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. III. THE PHYSIOLOGICAL DISPOSITION AND ANTIMALARIAL ACTIVITY OF THE CINCHONA ALKALOIDS. J Clin Invest 1948 1.13
65 The constitutive and stress inducible forms of hsp 70 exhibit functional similarities and interact with one another in an ATP-dependent fashion. J Cell Biol 1993 1.11
66 The two mammalian mitochondrial stress proteins, grp 75 and hsp 58, transiently interact with newly synthesized mitochondrial proteins. Cell Regul 1991 1.11
67 Reactive nitrogen species inhibit alveolar epithelial fluid transport after hemorrhagic shock in rats. J Immunol 2001 1.10
68 Intramitochondrial folding and assembly of medium-chain acyl-CoA dehydrogenase (MCAD). Demonstration of impaired transfer of K304E-variant MCAD from its complex with hsp60 to the native tetramer. J Biol Chem 1994 1.10
69 Characterization of a small, nonstructural viral polypeptide present late during infection of BHK cells by Semliki Forest virus. J Virol 1980 1.09
70 The mammalian stress response and the cytoskeleton: alterations in intermediate filaments. Ann N Y Acad Sci 1985 1.06
71 Disruption of the three cytoskeletal networks in mammalian cells does not affect transcription, translation, or protein translocation changes induced by heat shock. Mol Cell Biol 1985 1.06
72 Interleukin 1 and tumour necrosis factor increase phosphorylation of the small heat shock protein. Effects in fibroblasts, Hep G2 and U937 cells. FEBS Lett 1989 1.06
73 Induction of stress protein HSP70 in nerve cells after status epilepticus in the rat. Neurosci Lett 1989 1.02
74 Amino-terminal sequence analysis of alphavirus polypeptides. J Virol 1981 1.01
75 Growth arrest of human B lymphocytes is accompanied by induction of the low molecular weight mammalian heat shock protein (Hsp28). J Immunol 1992 0.97
76 NO generation and action during changes in salt intake: roles of nNOS and macula densa. Am J Physiol 1998 0.97
77 Strategies for correcting the delta F508 CFTR protein-folding defect. J Bioenerg Biomembr 1997 0.96
78 Short circuiting stress protein expression via a tyrosine kinase inhibitor, herbimycin A. J Cell Physiol 1995 0.93
79 Characterization and purification of the 94-kDa glucose-regulated protein. J Biol Chem 1991 0.93
80 Comparison of inhibitors of superoxide generation in vascular smooth muscle cells. Br J Pharmacol 2009 0.93
81 Role of nitric oxide in short-term and prolonged effects of angiotensin II on renal hemodynamics. Hypertension 1996 0.93
82 Interaction between nitric oxide and oxygen radicals in regulation of tubuloglomerular feedback. Acta Physiol Scand 2000 0.93
83 Oxidative stress: cause or consequence of hypertension. Exp Biol Med (Maywood) 2001 0.93
84 Benzoquinoid ansamycins (herbimycin A and geldanamycin) interfere with the maturation of growth factor receptor tyrosine kinases. Cell Stress Chaperones 1999 0.93
85 Co-translational interactions of apoprotein B with the ribosome and translocon during lipoprotein assembly or targeting to the proteasome. J Biol Chem 2001 0.93
86 TP receptor-mediated vasoconstriction in microperfused afferent arterioles: roles of O(2)(-) and NO. Am J Physiol Renal Physiol 2000 0.91
87 Molecular chaperones and the centrosome. A role for HSP 73 in centrosomal repair following heat shock treatment. J Biol Chem 1996 0.91
88 Geldanamycin inhibits NF-kappaB activation and interleukin-8 gene expression in cultured human respiratory epithelium. Am J Respir Cell Mol Biol 2001 0.90
89 Polyglutamine protein aggregation and toxicity are linked to the cellular stress response. Hum Mol Genet 2003 0.90
90 Tachyarrhythmias in young athletes. J Am Coll Cardiol 1986 0.90
91 Renal vasoconstriction during inhibition of NO synthase: effects of dietary salt. Kidney Int 1994 0.89
92 Stress preconditioning attenuates oxidative injury to the alveolar epithelium of the lung following haemorrhage in rats. J Physiol 2002 0.88
93 Thromboxane mediates renal hemodynamic response to infused angiotensin II. Kidney Int 1991 0.88
94 An Hsp60 related protein is associated with purified HIV and SIV. J Med Primatol 1994 0.88
95 STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. II. METHOD FOR THE QUANTITATIVE ASSAY OF SUPPRESSIVE ANTIMALARIAL ACTION IN FALCIPARUM MALARIA. J Clin Invest 1948 0.86
96 Activation primes human B lymphocytes to respond to heat shock. J Exp Med 1989 0.85
97 Constitutive expression of a groEL-related protein on the surface of human gamma/delta cells. J Exp Med 1990 0.85
98 Expression of heat shock proteins in a linear rodent wound. Wound Repair Regen 2002 0.85
99 Nitric oxide mediates renal vasodilation during erythropoietin-induced polycythemia. Kidney Int 1993 0.85
100 Evidence that heat shock protein-70 associated with progesterone receptors is not involved in receptor-DNA binding. Mol Endocrinol 1991 0.84
101 Interstellar molecules and dense clouds. Science 1971 0.84
102 Thromboxane mediation of the pressor response to infused angiotensin II. Am J Hypertens 1990 0.83
103 Renal tubular chloride and renin release. J Lab Clin Med 1987 0.83
104 STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. V. THE ANTIMALARIAL ACTIVITY OF QUINACRINE. J Clin Invest 1948 0.83
105 Mammalian cytosolic DnaJ homologues affect the hsp70 chaperone-substrate reaction cycle, but do not interact directly with nascent or newly synthesized proteins. Biochemistry 1998 0.83
106 Heat shock alters the composition of heteromeric steroid receptor complexes and enhances receptor activity in vivo. Biochemistry 1992 0.83
107 Effects of dietary salt intake on plasma arginine. Am J Physiol Regul Integr Comp Physiol 2001 0.82
108 Renal vasodilation with L-arginine. Effects of dietary salt. Hypertension 1995 0.82
109 Hsp72 induction: a potential molecular mediator of the delay phenomenon. Ann Plast Surg 2000 0.82
110 Chaperoning brain diseases. Nature 1998 0.82
111 Measurement of ventricular electrogram amplitude during intraoperative induction of ventricular tachyarrhythmias. Am J Cardiol 1992 0.81
112 Effects of NaCl on renin and aldosterone responses to potassium depletion. Am J Physiol 1983 0.81
113 Heat shock proteins bind calcitonin. Endocrinology 1990 0.80
114 Macula densa nitric oxide synthase: expression, regulation, and function. Kidney Int Suppl 1998 0.80
115 Heat shock proteins as biomarkers for stroke and trauma. Am J Med 2001 0.80
116 The response of guinea pig airway epithelial cells and alveolar macrophages to environmental stress. Am J Respir Cell Mol Biol 1991 0.80
117 AT1 and TxA2/PGH2 receptors maintain hypertension throughout 2K,1C Goldblatt hypertension in the rat. Am J Physiol 1996 0.80
118 Sympathetic nervous system and hypertension during prolonged TxA2/PGH2 receptor activation in rats. Am J Physiol 1997 0.79
119 Immunocytochemical response of type A and type B intercalated cells to increased sodium chloride delivery. Am J Physiol 1992 0.79
120 An immunoassay for heat shock protein 73/72: use of the assay to correlate HSP73/72 levels in mammalian cells with heat response. Int J Hyperthermia 1993 0.79
121 Central thromboxane receptors: mRNA expression and mediation of pressor responses. Am J Physiol 1997 0.79
122 STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. X. THE SUPPRESSIVE ANTIMALARIAL EFFECT OF PALUDRINE. J Clin Invest 1948 0.78
123 Abnormalities in stress proteins in prion diseases. Cell Mol Neurobiol 1998 0.78
124 Ventricular tachycardia due to bundle branch reentry: induction by spontaneous atrial premature beats. Am Heart J 1988 0.78
125 Renin secretion and loop of Henle chloride reabsorption in the adrenalectomized rat. Am J Physiol 1985 0.78
126 Angiotensin II and thromboxane in the regulation of blood pressure and renal function. Kidney Int Suppl 1990 0.78
127 STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. IV. THE METABOLISM OF CINCHONINE IN RELATION TO ITS ANTIMALARIAL ACTIVITY. J Clin Invest 1948 0.78
128 Modification of renin reactivity by lipids extracted from normal, hypertensive, and uremic plasma. J Clin Endocrinol Metab 1976 0.78
129 Sustained macroreentrant ventricular tachycardia. Am Heart J 1982 0.78
130 Modification of the enzymatic activity of renin by acidification of plasma and by exposure of plasma to cold temperatures. Hypertension 1980 0.77
131 Characterization and inducibility of hsp 70 proteins in the male mouse germ line. J Cell Biol 1990 0.77
132 Different mechanisms for the increased enzymatic activity of renin in plasma of patients with chronic renal failure and patients receiving glucocorticoid therapy. J Clin Endocrinol Metab 1980 0.77
133 Extracellular matrix regulates the hepatocellular heat shock response. J Surg Res 2000 0.76
134 Diet-induced protection against lipopolysaccharide includes increased hepatic NO production. J Surg Res 1999 0.76
135 Effect of salt deprivation on blood pressure in rats. Am J Physiol 1989 0.76
136 Renal vasoconstriction with U-46,619; role of arachidonate metabolites. J Am Soc Nephrol 1994 0.76
137 In vitro and in vivo inhibition of renin by fatty acids. Am J Physiol 1978 0.75
138 Mechanism of increased renin release in the adrenalectomized rat. Adrenal insufficiency and renin. Hypertension 1983 0.75
139 New hope in atrial fibrillation. J Am Coll Cardiol 1990 0.75
140 Effects of chlorpropamide on loop of Henle function and plasma renin. Kidney Int 1986 0.75
141 Cumulative effects of cycle length on ventricular refractoriness in man. Am Heart J 1990 0.75
142 Analysis of protein activity data by Gaussian stochastic process models. J Biopharm Stat 1999 0.75
143 Renal venous plasma renin reactivity in clinical and experimental renovascular hypertension: renin reactivity in renovascular hypertension. Nephron 1977 0.75
144 Star Formation in W49A: Gravitational Collapse of the Molecular Cloud Core Toward a Ring of Massive Stars. Science 1987 0.75
145 Wolff-Parkinson-White syndrome. Pacing Clin Electrophysiol 1983 0.75
146 Evidence for the existence of an acetone soluble renin inhibiting factor in normal human plasma. Circ Res 1975 0.75
147 Long-term therapy with disopyramide phosphate: side effects and effectiveness. Am Heart J 1986 0.75
148 Heat shock attenuates oxidation and accelerates apoptosis in human neutrophils. J Surg Res 1999 0.75
149 Pericardial repair of endocardial defect following regional endocardial resection for ventricular tachycardia. J Card Surg 1989 0.75
150 Medical aspects of congestive heart failure. 1. Cardiovasc Nurs 1967 0.75
151 Distal atrioventricular conduction system function. Cardiol Clin 1986 0.75
152 Proarrhythmia in patients treated with moricizine. Pacing Clin Electrophysiol 1992 0.75
153 Identification of p70 and p80 associations with class II MHC molecules and Ii. Am J Hematol 1990 0.75
154 Effect of adrenalectomy on renin release in the rat. Endocrinology 1983 0.75
155 Implantation of cardioverter defibrillators in the post-sternotomy patient. Ann Thorac Surg 1992 0.75
156 Gas jets associated with star formation. Science 1985 0.75
157 Mechanism for inhibition of renin release by acute plasma volume expansion in the dog. Am J Physiol 1985 0.75
158 A cloud collision model for water maser excitation. Astrophys J 1986 0.75
159 Paroxysmal fascicular tachycardia and ventricular tachycardia due to mechanical stimulation by a mitral valve prosthesis. J Am Coll Cardiol 1986 0.75
160 Venus: new microwave measurements show no atmospheric water vapor. Science 1973 0.75
161 Determination of iothalamate in rat urine, plasma, and tubular fluid by capillary electrophoresis. J Chromatogr B Biomed Sci Appl 1999 0.75
162 Inhibition of the in vitro renin reaction by circulating neutral lipids. Circ Res 1977 0.75
163 Does amplitude of the intracardiac electrogram change with time during ventricular fibrillation? Implications for fixed gain sensing devices. J Electrocardiol 1992 0.75
164 Role of AVP in pressor responses during activation of central TxA2/PGH2 receptors. Am J Physiol 1997 0.75
165 Role of volume and prostaglandin synthesis in the suppression of renin by saline in the rat. Proc Soc Exp Biol Med 1986 0.75