Published in Methods Enzymol on January 01, 1987
Physical maps of the six smallest chromosomes of Saccharomyces cerevisiae at a resolution of 2.6 kilobase pairs. Genetics (1993) 6.47
A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites. Genetics (1992) 5.37
Effects of null mutations and overexpression of capping protein on morphogenesis, actin distribution and polarized secretion in yeast. J Cell Biol (1992) 2.18
Identification and characterization of yeast mutants and the gene for a cruciform cutting endonuclease. EMBO J (1992) 1.69
Silent mitochondrial and active nuclear genes for subunit 2 of cytochrome c oxidase (cox2) in soybean: evidence for RNA-mediated gene transfer. EMBO J (1992) 1.42
Cloning and sequence of the Salmonella typhimurium hemL gene and identification of the missing enzyme in hemL mutants as glutamate-1-semialdehyde aminotransferase. J Bacteriol (1990) 1.42
Cloning, nucleotide sequence, expression, and chromosomal location of ldh, the gene encoding L-(+)-lactate dehydrogenase, from Lactococcus lactis. J Bacteriol (1992) 1.24
The alpha and beta subunits of nematode actin capping protein function in yeast. Mol Biol Cell (1993) 1.18
Promoter elements determining weak expression of the GAL4 regulatory gene of Saccharomyces cerevisiae. Mol Cell Biol (1993) 1.14
Mapping of the mouse actin capping protein beta subunit gene. BMC Genomics (2000) 0.75
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature (2000) 32.30
Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors. Science (1987) 17.15
Separation of chromosomal DNA molecules from yeast by orthogonal-field-alternation gel electrophoresis. Nucleic Acids Res (1984) 14.43
Electrophoretic separations of large DNA molecules by periodic inversion of the electric field. Science (1986) 13.57
A genetic linkage map of the human genome. Cell (1987) 13.37
An electrophoretic karyotype for yeast. Proc Natl Acad Sci U S A (1985) 11.84
Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o. Proc Natl Acad Sci U S A (1977) 10.64
The genome of the natural genetic engineer Agrobacterium tumefaciens C58. Science (2001) 6.90
Physical maps of the six smallest chromosomes of Saccharomyces cerevisiae at a resolution of 2.6 kilobase pairs. Genetics (1993) 6.47
Random-clone strategy for genomic restriction mapping in yeast. Proc Natl Acad Sci U S A (1986) 6.44
Systematic screening of yeast artificial-chromosome libraries by use of the polymerase chain reaction. Proc Natl Acad Sci U S A (1990) 6.20
A new method for purifying lambda DNA from phage lysates. DNA (1985) 5.69
Isolation of single-copy human genes from a library of yeast artificial chromosome clones. Science (1989) 5.29
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest (2000) 5.12
Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly. Nat Genet (1996) 3.50
Identification of the yeast DNA sequences that correspond to specific tyrosine-inserting nonsense suppressor loci. J Mol Biol (1979) 3.29
Identification of more than 500 RFLPs by screening random genomic clones. Am J Hum Genet (1988) 3.01
Detection and characterization of chimeric yeast artificial-chromosome clones. Genomics (1991) 2.96
Chromosomal region of the cystic fibrosis gene in yeast artificial chromosomes: a model for human genome mapping. Science (1990) 2.92
Concerted deletions and inversions are caused by mitotic recombination between delta sequences in Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.56
Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis. J Bacteriol (2004) 2.47
Insertion of a repetitive element at the same position in the 5'-flanking regions of two dissimilar yeast tRNA genes. Proc Natl Acad Sci U S A (1982) 2.44
Cloning of the yeast tyrosine transfer RNA genes in bacteriophage lambda. J Mol Biol (1979) 2.44
Physical map of the Saccharomyces cerevisiae genome at 110-kilobase resolution. Genetics (1991) 2.43
The DNA sequence and biological annotation of human chromosome 1. Nature (2006) 2.42
Multiple-complete-digest restriction fragment mapping: generating sequence-ready maps for large-scale DNA sequencing. Proc Natl Acad Sci U S A (1997) 2.36
Effects of altered 5'-flanking sequences on the in vivo expression of a Saccharomyces cerevisiae tRNATyr gene. Mol Cell Biol (1984) 2.35
Transcription and processing of cloned yeast tyrosine tRNA genes microinjected into frog oocytes. Nature (1979) 2.30
Cloning human telomeric DNA fragments into Saccharomyces cerevisiae using a yeast-artificial-chromosome vector. Proc Natl Acad Sci U S A (1989) 2.10
The CEPH consortium linkage map of human chromosome 1. Genomics (1991) 2.09
Computer-based image analysis of one-dimensional electrophoretic gels used for the separation of DNA restriction fragments. Nucleic Acids Res (1984) 2.05
Mutation of the non-Mendelian suppressor, Psi, in yeast by hypertonic media. Proc Natl Acad Sci U S A (1979) 1.92
Only one of two closely related yeast suppressor tRNA genes contains an intervening sequence. Nature (1981) 1.87
Identification of a genomic island present in the majority of pathogenic isolates of Pseudomonas aeruginosa. J Bacteriol (2001) 1.85
Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis. J Neurosci (1986) 1.84
Intraneuronal substance P contributes to the severity of experimental arthritis. Science (1984) 1.77
Assembly of high-resolution restriction maps based on multiple complete digests of a redundant set of overlapping clones. Genomics (1996) 1.72
Microinjection of intact 200- to 500-kb fragments of YAC DNA into mammalian cells. Genomics (1993) 1.71
Physical analysis of the CYC1-sup4 interval in Saccharomyces cerevisiae. Mol Cell Biol (1981) 1.68
Scan of human genome reveals no new Loci under ancient balancing selection. Genetics (2006) 1.68
Identification of a second pseudoautosomal region near the Xq and Yq telomeres. Science (1992) 1.67
7q11.23 deletions in Williams syndrome arise as a consequence of unequal meiotic crossover. Am J Hum Genet (1996) 1.64
Systems errors versus physicians' errors: finding the balance in medical education. Acad Med (1999) 1.61
Orthogonal-field-alternation gel electrophoresis. Methods Enzymol (1987) 1.54
The maps. Clone by clone by clone. Nature (2001) 1.52
Oligodeoxynucleotide-directed mutagenesis of Escherichia coli and yeast by simple cotransformation of the primer and template. DNA (1986) 1.51
Preparation of clone libraries in yeast artificial-chromosome vectors. Methods Enzymol (1991) 1.51
The human HPRT gene on a yeast artificial chromosome is functional when transferred to mouse cells by cell fusion. Genomics (1991) 1.49
A chromosomal translocation causing overproduction of iso-2-cytochrome c in yeast. Genetics (1978) 1.45
Molecular characterisation of the tyrosine tRNA genes of yeast. Nature (1977) 1.44
A time to sequence. Science (1995) 1.37
Second-generation approach to the construction of yeast artificial-chromosome libraries. Genomics (1990) 1.36
Chromosome mapping of the CYC7 gene determining yeast iso-2-cytochrome c: structural and regulatory regions. Proc Natl Acad Sci U S A (1978) 1.31
Mapping of the Saccharomyces cerevisiae CDC3, CDC25, and CDC42 genes to chromosome XII by chromosome blotting and tetrad analysis. Yeast (1987) 1.29
Regional and physical mapping studies characterizing the Greig polysyndactyly 3;7 chromosome translocation, t(3;7)(p21.1;p13). Genomics (1989) 1.27
Error checking and graphical representation of multiple-complete-digest (MCD) restriction-fragment maps. Genome Res (1999) 1.27
Transposition of the gene cluster CYC1-OSM1-RAD7 in yeast. J Mol Biol (1981) 1.22
Factors which equalize the representation of genome segments in recombinant libraries. Gene (1986) 1.21
Cosmid mapping of the human chorionic gonadotropin beta subunit genes by field-inversion gel electrophoresis. Nucleic Acids Res (1987) 1.19
Cloning and in vivo expression of the human GART gene using yeast artificial chromosomes. EMBO J (1991) 1.19
Nonsense mutations in essential genes of Saccharomyces cerevisiae. Genetics (1988) 1.16
Drug-induced methemoglobinemia. Semin Hematol (1973) 1.16
Automated percutaneous discectomy: a prospective multi-institutional study. Neurosurgery (1990) 1.16
Linkage of preaxial polydactyly type 2 to 7q36. Am J Med Genet (1995) 1.13
Systematic generation of sequence-tagged sites for physical mapping of human chromosomes: application to the mapping of human chromosome 7 using yeast artificial chromosomes. Genomics (1991) 1.12
A genomic sequence analysis of the mouse and human microtubule-associated protein tau. Mamm Genome (2001) 1.11
The application of molecular and immunologic techniques to study the epidemiology of Legionella pneumophila serogroup 1. Diagn Microbiol Infect Dis (1990) 1.07
Identification and characterization of 23 RFLP loci by screening random cosmid genomic clones. Am J Hum Genet (1989) 1.07
Consistent association between sigma elements and tRNA genes in yeast. Proc Natl Acad Sci U S A (1983) 1.06
Beta 2-adrenergic mechanisms in experimental arthritis. Proc Natl Acad Sci U S A (1988) 1.03
Metaphase and interphase cytogenetics with Alu-PCR-amplified yeast artificial chromosome clones containing the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erbB-2. Cancer Res (1992) 1.02
Purinergic regulation of bradykinin-induced plasma extravasation and adjuvant-induced arthritis in the rat. Proc Natl Acad Sci U S A (1991) 1.00
Epinephrine exacerbates arthritis by an action at presynaptic B2-adrenoceptors. Neuroscience (1990) 0.99
Two chromosome 7 dinucleotide repeat polymorphisms at gene loci epidermal growth factor receptor (EGFR) and pro alpha 2 (I) collagen (COL1A2). Hum Mol Genet (1992) 0.96
The yeast cloning vector YEp13 contains a tRNALeu3 gene that can mutate to an amber suppressor. Gene (1984) 0.96
Mapping human telomere regions with YAC and P1 clones: chromosome-specific markers for 27 telomeres including 149 STSs and 24 polymorphisms for 14 proterminal regions. Genomics (1996) 0.94
Increasing sympathetic nerve terminal-dependent plasma extravasation correlates with decreased arthritic joint injury in rats. Neuroscience (1991) 0.89
Physical calibration of yeast artificial chromosome contig maps by RecA-assisted restriction endonuclease (RARE) cleavage. Genomics (1994) 0.89
Mdm2 controls CREB-dependent transactivation and initiation of adipocyte differentiation. Cell Death Differ (2012) 0.88
Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis. J Med Genet (2004) 0.88
VNTR and microsatellite polymorphisms within the subtelomeric region of 7q. Am J Hum Genet (1993) 0.87
Automated percutaneous diskectomy: initial patient experience. Work in progress. Radiology (1987) 0.84
High levels of loss at the 17p telomere suggest the close proximity of a tumour suppressor. Br J Cancer (1996) 0.83
Lessons in cooperation: four hospital consortia relate their quality improvement experiences. Jt Comm J Qual Improv (1995) 0.83
Spatial normalization of one-dimensional electrophoretic gel images. Genomics (1990) 0.82
Vaccines, biological warfare, and bioterrorism. Prim Care (2001) 0.82
Differential effects of acetylsalicylic acid and acetaminophen on sleep abnormalities in a rat chronic pain model. Brain Res (1989) 0.81
A 2-cM genetic linkage map of human chromosome 7p that includes 47 loci. Genomics (1992) 0.80
Automated percutaneous discectomy: preliminary experience. Acta Neurochir Suppl (Wien) (1988) 0.80
Sequence-ready contig for the 1.4-cM ductal carcinoma in situ loss of heterozygosity region on chromosome 8p22-p23. Genomics (1999) 0.80
Chronically administered nicotine attenuates bradykinin-induced plasma extravasation and aggravates arthritis-induced joint injury in the rat. Neuroscience (1992) 0.79
Automated percutaneous discectomy. Spine (Phila Pa 1976) (1991) 0.78
Evaluation of the Amicus Separator in the collection of apheresis platelets. Transfusion (1998) 0.78