Published in Am J Hum Genet on November 01, 1988
Presymptomatic testing for Huntington's disease in the United Kingdom. The United Kingdom Huntington's Disease Prediction Consortium. BMJ (1992) 2.69
Non-random association between alleles detected at D4S95 and D4S98 and the Huntington's disease gene. J Med Genet (1989) 1.95
Opinion: predictive testing for Huntington disease in childhood: challenges and implications. Am J Hum Genet (1990) 1.75
Different options for prenatal testing for Huntington's disease using DNA probes. J Med Genet (1989) 1.22
Ethical and legal dilemmas arising during predictive testing for adult-onset disease: the experience of Huntington disease. Am J Hum Genet (1990) 1.20
Huntington's disease and the ethics of genetic prediction. J Med Ethics (1992) 1.15
Risk reversals in predictive testing for Huntington disease. Am J Hum Genet (1997) 1.06
Attitudes of general practitioners to presymptomatic testing for Huntington's disease. J Med Genet (1990) 1.01
Methylation at the Huntington disease-linked D4S95 locus. Am J Hum Genet (1989) 1.01
Linkage disequilibrium and modification of risk for Huntington disease. Am J Hum Genet (1991) 1.00
Huntington disease in Finland: linkage disequilibrium of chromosome 4 RFLP haplotypes and exclusion of a tight linkage between the disease and D4S43 locus. Am J Hum Genet (1990) 0.86
Clinical consequences of isolating the gene for Huntington's disease. BMJ (1993) 0.83
Exclusion testing in pregnancy for Huntington's disease. J Med Genet (1990) 0.82
Ethical and social issues in presymptomatic testing for Huntington's disease: a European Community collaborative study. European Community Huntington's Disease Collaborative Study Group. J Med Genet (1993) 0.81
Presymptomatic Diagnosis of Genetic Disorders: Is it worth the anxiety? Can Fam Physician (1991) 0.75
A polymorphic DNA marker genetically linked to Huntington's disease. Nature (1984) 16.71
A highly polymorphic locus very tightly linked to the Huntington's disease gene. Nature (1988) 3.90
Predictive testing for Huntington's disease with use of a linked DNA marker. N Engl J Med (1988) 3.82
A DNA segment encoding two genes very tightly linked to Huntington's disease. Science (1987) 2.63
Exclusion testing for Huntington's disease in pregnancy with a closely linked DNA marker. Lancet (1987) 2.09
First-trimester prenatal diagnosis for Huntington's disease with DNA probes. Lancet (1987) 1.70
DNA polymorphisms in and around the Apo-A1-CIII genes and genetic hyperlipidemias. Am J Hum Genet (1987) 1.61
Huntington disease: estimation of heterozygote status using linked genetic markers. Genet Epidemiol (1984) 1.39
A polymorphic DNA marker that represents a conserved expressed sequence in the region of the Huntington disease gene. Am J Hum Genet (1988) 1.39
Genetic prediction and family structure in Huntington's chorea. Br Med J (Clin Res Ed) (1985) 1.38
A physical map of 30,000 human genes. Science (1998) 12.43
Construction of a GT polymorphism map of human 9q. Genomics (1992) 8.92
The psychological consequences of predictive testing for Huntington's disease. Canadian Collaborative Study of Predictive Testing. N Engl J Med (1992) 5.51
The association of social relationships and activities with mortality: prospective evidence from the Tecumseh Community Health Study. Am J Epidemiol (1982) 4.42
A highly polymorphic locus very tightly linked to the Huntington's disease gene. Nature (1988) 3.90
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nat Genet (2002) 3.67
Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5. Am J Hum Genet (1988) 3.58
Localization of a susceptibility locus for schizophrenia on chromosome 5. Nature (1988) 3.44
Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia. Am J Hum Genet (2001) 3.27
Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma. Nature (1988) 3.27
Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia. Mol Psychiatry (1999) 2.80
Prevalence of repetitive and reward-seeking behaviors in Parkinson disease. Neurology (2006) 2.70
TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. J Exp Med (1998) 2.68
CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat Genet (1999) 2.60
Correlation of the highest-energy cosmic rays with nearby extragalactic objects. Science (2007) 2.57
Predictive testing for Huntington disease in Canada: adverse effects and unexpected results in those receiving a decreased risk. Am J Med Genet (1992) 2.39
Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)n. Nucleic Acids Res (1990) 2.23
Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis. Am J Pathol (1997) 2.19
Strategies for mutational analysis of the large multiexon ATM gene using high-density oligonucleotide arrays. Genome Res (1998) 2.17
A worldwide assessment of the frequency of suicide, suicide attempts, or psychiatric hospitalization after predictive testing for Huntington disease. Am J Hum Genet (1999) 2.12
Postnatal growth of the mouse lung. J Anat (1977) 2.10
[Trisomy 21 and superoxide dismutase-1 (IPO-A). Tentative localization of sub-band 21Q22.1]. Exp Cell Res (1976) 2.07
Modulation of HIV-like particle assembly in vitro by inositol phosphates. Proc Natl Acad Sci U S A (2001) 2.07
Mercury exposure and risks from dental amalgam in the US population, post-2000. Sci Total Environ (2011) 1.97
Non-random association between alleles detected at D4S95 and D4S98 and the Huntington's disease gene. J Med Genet (1989) 1.95
Complex patterns of linkage disequilibrium in the Huntington disease region. Am J Hum Genet (1991) 1.84
Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. Nat Genet (1992) 1.76
Cerebral effects of rewarming following prolonged hypothermia: significance for the management of severe cranio-cerebral injury and acute pyrexia. Brain (1967) 1.75
Investigation of under-ascertainment in epidemiological studies based in general practice. Int J Epidemiol (1999) 1.73
Prospective prevalence of pathologic gambling and medication association in Parkinson disease. Neurology (2006) 1.72
First-trimester prenatal diagnosis for Huntington's disease with DNA probes. Lancet (1987) 1.70
What women want - quantifying the perception of hair amount: an analysis of hair diameter and density changes with age in caucasian women. Br J Dermatol (2012) 1.69
The alpha1-fetoprotein locus is activated by a nuclear receptor of the Drosophila FTZ-F1 family. Mol Cell Biol (1996) 1.66
Incorporating language phenotypes strengthens evidence of linkage to autism. Am J Med Genet (2001) 1.65
Evidence from family studies that the gene causing Huntington disease is telomeric to D4S95 and D4S90. Am J Hum Genet (1989) 1.64
Establishing safe injecting rooms in Australia: attitudes of injecting drug users. Aust N Z J Public Health (1999) 1.58
Sex differences in psychosocial consequences of alcohol and drug abuse. J Health Soc Behav (1989) 1.57
Genome-wide association study of obsessive-compulsive disorder. Mol Psychiatry (2012) 1.57
HSF1 granules: a novel stress-induced nuclear compartment of human cells. J Cell Sci (1997) 1.57
Behavior modification in the treatment of obesity. Psychosom Med (1971) 1.56
Rilpivirine versus efavirenz in HIV-1-infected subjects receiving emtricitabine/tenofovir DF: pooled 96-week data from ECHO and THRIVE Studies. HIV Clin Trials (2013) 1.53
Lipid infusion in the management of poisoning: a report of 6 canine cases. Vet Rec (2013) 1.51
National standard for measurement of resting and ambulatory blood pressures with automated sphygmomanometers. Hypertension (1993) 1.50
Measurement of the depth of maximum of extensive air showers above 10{18} eV. Phys Rev Lett (2010) 1.48
Action of baclofen on mammalian synaptic transmission. Neuroscience (1978) 1.48
Predictive testing for Huntington disease: II. Demographic characteristics, life-style patterns, attitudes, and psychosocial assessments of the first fifty-one test candidates. Am J Med Genet (1989) 1.46
Treatment of acute gastroenteritis: too much and too little care. Clin Pediatr (Phila) (1996) 1.44
Prognostic value of angiogenesis in operable non-small cell lung cancer. J Pathol (1996) 1.42
Availability of lipid emulsion in obstetric anaesthesia in the UK: a national questionnaire survey. Anaesthesia (2008) 1.41
Serotonin transporter polymorphism, memory and hippocampal volume in the elderly: association and interaction with cortisol. Mol Psychiatry (2007) 1.40
Manufacture of multiple personality disorder. Br J Psychiatry (1992) 1.39
Revisiting HIV/AIDS. Can Nurse (2000) 1.39
A polymorphic DNA marker that represents a conserved expressed sequence in the region of the Huntington disease gene. Am J Hum Genet (1988) 1.39
[Circumcision for boys incapable of giving informed consent]. Urologe A (2009) 1.39
Relationship of resting brain hyperconnectivity and schizophrenia-like symptoms produced by the NMDA receptor antagonist ketamine in humans. Mol Psychiatry (2013) 1.31
Human monoamine oxidase gene (MAOA): chromosome position (Xp21-p11) and DNA polymorphism. Genomics (1988) 1.30
Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35. Nat Genet (1994) 1.28
Nail gun injuries. J Trauma (1993) 1.27
Pathways to adolescent drug use: self-derogation, peer influence, weakening of social controls, and early substance use. J Health Soc Behav (1984) 1.25
Proceed with care: direct predictive testing for Huntington disease. Am J Hum Genet (1994) 1.25
Cu/Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis. J Neurochem (1994) 1.25
Prevalence of cervical pathogens in women with and without inflammatory changes on smear testing. BMJ (1993) 1.23
A contig of non-chimaeric YACs containing the spinal muscular atrophy gene in 5q13. Hum Mol Genet (1993) 1.23
Hepatic origin of cholesteryl oleate in coronary artery atherosclerosis in African green monkeys. Enrichment by dietary monounsaturated fat. J Clin Invest (1997) 1.22
Different options for prenatal testing for Huntington's disease using DNA probes. J Med Genet (1989) 1.22
A role for a pyridoxne derivative in the multivalent repression of the isoleucine and valine biosynthetic enzymes. Biochem Biophys Res Commun (1973) 1.22
Predictive testing for Huntington disease: I. Description of a pilot project in British Columbia. Am J Med Genet (1989) 1.21
Breast cancer screening: the underuse of mammography. Radiology (1985) 1.20
Investigation of depth dependent changes in cerebral haemodynamics during face perception in infants. Phys Med Biol (2007) 1.20
Ethical and legal dilemmas arising during predictive testing for adult-onset disease: the experience of Huntington disease. Am J Hum Genet (1990) 1.20
Implementing the NACNE report. 1. National dietary goals: a confused debate. Lancet (1983) 1.18
Intranuclear localization of human papillomavirus 16 E7 during transformation and preferential binding of E7 to the Rb family member p130. Proc Natl Acad Sci U S A (1999) 1.17
Cystathionine beta synthase: gene dosage effect in trisomy 21. Biochem Biophys Res Commun (1985) 1.15
Immediate mobilization of fractures of the neck of the fifth metacarpal. Injury (1986) 1.15
Bcl-2 and p53 expression in node-negative breast carcinoma: a study with long-term follow-up. Hum Pathol (1996) 1.15
Influence of social class on obesity and thinness in children. JAMA (1972) 1.14
FLT4, a novel class III receptor tyrosine kinase in chromosome 5q33-qter. Cancer Res (1992) 1.13
Early adult psychological consequences for males of adolescent pregnancy and its resolution. J Youth Adolesc (1990) 1.13
Long-term immunological response in HIV-1-infected subjects receiving potent antiretroviral therapy. AIDS (2000) 1.13
Assignment of human 3-hydroxy-3-methylglutaryl coenzyme A reductase gene to q13----q23 region of chromosome 5. Somat Cell Mol Genet (1986) 1.12
Comparative study of lymph node cytology by puncture and histopathology. Acta Cytol (1967) 1.11
A DNA probe, D5 [D4S90] mapping to human chromosome 4p16.3. Nucleic Acids Res (1988) 1.11
New albumin gene 3' adjacent to the alpha 1-fetoprotein locus. J Biol Chem (1994) 1.10
Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer. Oncogene (2006) 1.10
Practical low-fat diets. Lancet (1982) 1.09
Imaging of pyelonephritis. Pediatr Radiol (1997) 1.09
Phase II study of estramustine and vinblastine, two microtubule inhibitors, in hormone-refractory prostate cancer. J Clin Oncol (1992) 1.09
The acute ghrelin response to a psychological stress challenge does not predict the post-stress urge to eat. Psychoneuroendocrinology (2007) 1.08
Five year study of prenatal testing for Huntington's disease: demand, attitudes, and psychological assessment. J Med Genet (1993) 1.08
An intervention to increase mammography screening by residents in family practice. J Fam Pract (1985) 1.08