S C Elgin

Author PubWeight™ 164.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The organization, expression, and evolution of antibody genes and other multigene families. Annu Rev Genet 1975 5.87
2 The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence. Cell 1979 5.83
3 Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol Cell Biol 1986 5.77
4 Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. Proc Natl Acad Sci U S A 1990 5.55
5 The chromatin structure of specific genes: II. Disruption of chromatin structure during gene activity. Cell 1979 5.13
6 Distribution patterns of HP1, a heterochromatin-associated nonhistone chromosomal protein of Drosophila. Eur J Cell Biol 1989 4.52
7 Position effect variegation in Drosophila is associated with an altered chromatin structure. Genes Dev 1995 4.41
8 The HP1 protein family: getting a grip on chromatin. Curr Opin Genet Dev 2000 4.34
9 Chromosomal proteins and chromatin structure. Annu Rev Biochem 1975 3.74
10 DNase I hypersensitive sites in Drosophila chromatin occur at the 5' ends of regions of transcription. Proc Natl Acad Sci U S A 1981 3.39
11 Selected topics in chromatin structure. Annu Rev Genet 1985 3.18
12 Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome. Proc Natl Acad Sci U S A 1984 2.69
13 Protein/DNA architecture of the DNase I hypersensitive region of the Drosophila hsp26 promoter. EMBO J 1988 2.62
14 (CT)n (GA)n repeats and heat shock elements have distinct roles in chromatin structure and transcriptional activation of the Drosophila hsp26 gene. Mol Cell Biol 1993 2.52
15 Anatomy of hypersensitive sites. Nature 1984 2.50
16 Limited heterogeneity of the major nonhistone chromosomal proteins. Biochemistry 1970 2.45
17 Drosophila nuclear proteins bind to regions of alternating C and T residues in gene promoters. Science 1989 2.42
18 Architectural variations of inducible eukaryotic promoters: preset and remodeling chromatin structures. Bioessays 1994 2.38
19 Chromatin structure and gene activity: the role of nonhistone chromosomal proteins. CRC Crit Rev Biochem 1982 2.31
20 A histone variant, H2AvD, is essential in Drosophila melanogaster. Mol Biol Cell 1992 2.18
21 Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles. EMBO J 1999 2.01
22 Molecular cloning of a human homologue of Drosophila heterochromatin protein HP1 using anti-centromere autoantibodies with anti-chromo specificity. J Cell Sci 1993 1.90
23 Boundary functions in the control of gene expression. Trends Genet 1991 1.90
24 Nucleosomal instability and induction of new upstream protein-DNA associations accompany activation of four small heat shock protein genes in Drosophila melanogaster. Mol Cell Biol 1986 1.81
25 The fourth chromosome of Drosophila melanogaster: interspersed euchromatic and heterochromatic domains. Proc Natl Acad Sci U S A 2000 1.79
26 Micrococcal nuclease as a probe of DNA sequence organization and chromatin structure. Cell 1981 1.77
27 Characterization of sequences associated with position-effect variegation at pericentric sites in Drosophila heterochromatin. Chromosoma 1998 1.77
28 Chromatin. Ga-ga over GAGA factor. Curr Biol 1995 1.77
29 Cleavage of chromatin with methidiumpropyl-EDTA . iron(II). Proc Natl Acad Sci U S A 1983 1.71
30 Localization of specific topoisomerase I interactions within the transcribed region of active heat shock genes by using the inhibitor camptothecin. Mol Cell Biol 1987 1.71
31 Nucleosome positioning and gene regulation. J Cell Biochem 1994 1.62
32 Chromosomal proteins of Drosophila embryos. Biochemistry 1973 1.57
33 A method for determination of the in situ distribution of chromosomal proteins. Proc Natl Acad Sci U S A 1976 1.53
34 Putting boundaries on silence. Cell 1999 1.51
35 Long-range nucleosome ordering is associated with gene silencing in Drosophila melanogaster pericentric heterochromatin. Mol Cell Biol 2001 1.46
36 Promoter sequence containing (CT)n.(GA)n repeats is critical for the formation of the DNase I hypersensitive sites in the Drosophila hsp26 gene. J Mol Biol 1992 1.43
37 Regulating genes by packaging domains: bits of heterochromatin in euchromatin? Trends Genet 1993 1.41
38 Optimal heat-induced expression of the Drosophila hsp26 gene requires a promoter sequence containing (CT)n.(GA)n repeats. J Mol Biol 1990 1.35
39 Analysis of Drosophila chromatin structure in vivo. Methods Enzymol 1999 1.35
40 Drosophila has a single copy of the gene encoding a highly conserved histone H2A variant of the H2A.F/Z type. Nucleic Acids Res 1988 1.34
41 Analysis of chromatin structure and DNA sequence organization: use of the 1,10-phenanthroline-cuprous complex. Nucleic Acids Res 1982 1.34
42 DNA representation of variegating heterochromatic P-element inserts in diploid and polytene tissues of Drosophila melanogaster. Chromosoma 1996 1.31
43 Chromatin organization and transcriptional control of gene expression in Drosophila. Gene 2000 1.31
44 TATA box-dependent protein-DNA interactions are detected on heat shock and histone gene promoters in nuclear extracts derived from Drosophila melanogaster embryos. Mol Cell Biol 1988 1.23
45 DNase I hypersensitive sites of the chromatin for Drosophila melanogaster ribosomal protein 49 gene. Nucleic Acids Res 1981 1.23
46 Heterochromatin protein 1, a known suppressor of position-effect variegation, is highly conserved in Drosophila. Nucleic Acids Res 1992 1.20
47 Chromatin structure, DNA structure. Nature 1982 1.20
48 A high-mobility-group protein and its cDNAs from Drosophila melanogaster. Mol Cell Biol 1992 1.20
49 Chemical footprinting of 5S RNA chromatin in embryos of Drosophila melanogaster. EMBO J 1984 1.19
50 A protein released by DNAase I digestion of drosophila nuclei is preferentially associated with puffs. Cell 1978 1.19
51 Distribution patterns of three subfractions of drosophila nonhistone chromosomal proteins: possible correlations with gene activity. Cell 1977 1.14
52 The role of a positioned nucleosome at the Drosophila melanogaster hsp26 promoter. EMBO J 1995 1.13
53 Micrococcal nuclease as a DNA structural probe: its recognition sequences, their genomic distribution and correlation with DNA structure determinants. J Mol Biol 1986 1.13
54 UV cross-linking identifies four polypeptides that require the TATA box to bind to the Drosophila hsp70 promoter. Mol Cell Biol 1990 1.13
55 Chromatin boundaries: punctuating the genome. Curr Biol 1998 1.11
56 Conservation of intron position indicates separation of major and variant H2As is an early event in the evolution of eukaryotes. J Mol Evol 1990 1.11
57 Characterization of a supercoil-dependent S1 sensitive site 5' to the Drosophila melanogaster hsp 26 gene. Nucleic Acids Res 1986 1.10
58 Raising large quantities of Drosophila for biochemical experiments. Methods Cell Biol 1994 1.09
59 Patterns of DNA structural polymorphism and their evolutionary implications. Cell 1984 1.08
60 Antibodies to proteins dissolved in sodium dodecyl sulfate. J Immunol 1974 1.07
61 Multiple forms and cellular localization of Drosophila DNA topoisomerase II. J Biol Chem 1986 1.06
62 Monoclonal antibodies against a specific nonhistone chromosomal protein of Drosophila associated with active genes. J Cell Biol 1981 1.05
63 Distribution studies on polytene chromosomes using antibodies directed against hnRNP. J Cell Biol 1981 1.04
64 Chromatin structure in pre- and postblastula embryos of Drosophila. Dev Biol 1983 1.04
65 Hsp28stl: a P-element insertion mutation that alters the expression of a heat shock gene in Drosophila melanogaster. Genetics 1987 1.00
66 A unique zinc finger protein is associated preferentially with active ecdysone-responsive loci in Drosophila. Genes Dev 1991 0.98
67 An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin. J Cell Sci 1997 0.98
68 Partial fractionation and chemical characterization of the major nonhistone chromosomal proteins. Biochemistry 1972 0.97
69 A Drosophila melanogaster H3.3 cDNA encodes a histone variant identical with the vertebrate H3.3. Gene 1991 0.95
70 A histone protease of rat liver chromatin. Biochem Biophys Res Commun 1972 0.94
71 Transcription of heat shock loci of Drosophila in a nuclear system. Biochemistry 1981 0.93
72 Nonhistone chromosomal proteins of rat tissues. A comparative study by gel electrophoresis. Biochemistry 1973 0.92
73 Nonenzymatic cleavage of chromatin. Methods Enzymol 1989 0.89
74 Immunofluorescent techniques in the analysis of chromosomal proteins. Methods Cell Biol 1978 0.89
75 Distribution patterns of Drosophila nonhistone chromosomal proteins. Cold Spring Harb Symp Quant Biol 1978 0.89
76 Supercoil-dependent features of DNA structure at Drosophila locus 67B1. J Mol Biol 1984 0.89
77 Preparation of Drosophila nuclei. Methods Cell Biol 1994 0.87
78 A prologue to the study of the nonhistone chromosomal proteins. Cold Spring Harb Symp Quant Biol 1974 0.87
79 Production and characterization of antisera against three individual NHC proteins; a case of a generally distributed NHC protein. Chromosoma 1978 0.86
80 Pushing nucleosomes around. Chromatin. Curr Biol 1996 0.85
81 Production of antibodies using proteins in gel bands. Methods Mol Biol 1994 0.84
82 Distribution of chromosomal proteins in polytene chromosomes of Drosophila. Methods Cell Biol 1991 0.84
83 A cytological approach to the ordering of events in gene activation using the Sgs-4 locus of Drosophila melanogaster. J Cell Biol 1984 0.84
84 Chromatin structure at the 44D larval cuticle gene locus in Drosophila: the effect of a transposable element insertion. Nucleic Acids Res 1984 0.83
85 Association of topoisomerase I with transcriptionally active loci in Drosophila. NCI Monogr 1987 0.83
86 Isoelectric focusing of proteins exposed to sodium dodecyl sulfate. Anal Biochem 1974 0.83
87 Nucleosome repeat structure is present in native salivary chromosomes of Drosophila melanogaster. J Cell Biol 1982 0.83
88 Insensitivity of the present hsp26 chromatin structure to a TATA box mutation in Drosophila. J Biol Chem 1994 0.82
89 Isolation and distribution of a Drosophila protein preferentially associated with inactive regions of the genome. Chromosoma 1987 0.82
90 The proteins of polytene chromosomes of Drosophila hydei. Chromosoma 1975 0.82
91 Immunofluorescent analysis of chromatin structure in relation to gene activity: a speculative essay. Curr Top Dev Biol 1979 0.81
92 The nonhistone chromosomal proteins of vertebrate liver and kidney: a comparative study by gel electrophoresis. J Mol Evol 1975 0.81
93 Analysis of DNA structural patterns and sequence organization at the larval cuticle locus in Drosophila melanogaster. Mol Cell Biol 1983 0.80
94 Chromosomes and expression mechanisms. Curr Opin Genet Dev 1997 0.79
95 Cleavage reagents as probes of DNA sequence organization and chromatin structure: Drosophila melanogaster locus 67B1. Cold Spring Harb Symp Quant Biol 1983 0.79
96 Sequence of histone 2B of Drosophila melanogaster. Biochemistry 1979 0.79
97 Methods for isolation and characterization of nonhistone chromosomal proteins. Methods Enzymol 1975 0.78
98 Production of antibodies using proteins in gel bands. Methods Mol Biol 1988 0.77
99 A heat-shock-activated cDNA encoding GAGA factor rescues some lethal mutations in the Drosophila melanogaster Trithorax-like gene. Genet Res 2001 0.76
100 Chromatin structure of a P-element-transduced hsp-28 gene in Drosophila melanogaster. Mol Cell Biol 1986 0.75
101 Proteins of metaphase chromosomes and interphase chromatin. Nucleic Acids Res 1980 0.75
102 5'-Mercuri-uridine triphosphate as a substrate for transcription. Anal Biochem 1982 0.75
103 An immunofluorescent analysis of Drosophila polytene chromosomes with antisera directed against H3, H4, and a native H3-H4 complex. Exp Cell Res 1978 0.75
104 Chromatin structure and gene expression in Drosophila. Anat Rec Suppl 1983 0.75