Published in Ann Rheum Dis on April 01, 1987
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Studies on the mechanism of inhibition of chemotactic tripeptide stimulated human neutrophil polymorphonuclear leucocyte superoxide production by chloroquine and hydroxychloroquine. Ann Rheum Dis (1987) 0.77
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The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature (1984) 28.58
Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature (1984) 25.71
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Phorbol diester receptor copurifies with protein kinase C. Proc Natl Acad Sci U S A (1983) 6.25
Turnover of inositol phospholipids and signal transduction. Science (1984) 5.76
The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase. Biochem J (1986) 4.35
Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme. J Exp Med (1984) 3.79
Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator. Nature (1985) 3.73
Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase. Eur J Biochem (1985) 3.04
Oxidation-reduction properties of the cytochrome b found in the plasma-membrane fraction of human neutrophils. A possible oxidase in the respiratory burst. Biochem J (1981) 2.56
Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein. Nature (1985) 2.46
Association of phorbol ester-induced hyperphosphorylation and reversible regulation of transferrin membrane receptors in HL60 cells. Proc Natl Acad Sci U S A (1984) 2.14
Chemoattractant receptor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in human polymorphonuclear leukocyte membranes. Requirement for a guanine nucleotide regulatory protein. J Biol Chem (1985) 2.03
A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters. Nature (1985) 1.83
The superoxide-generating oxidase of leucocytes. NADPH-dependent reduction of flavin and cytochrome b in solubilized preparations. Biochem J (1984) 1.80
Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils. J Biol Chem (1985) 1.80
Role of intracellular calcium mobilization in the regulation of protein kinase C-mediated membrane processes. Nature (1985) 1.61
Role for mouse macrophage IgG Fc receptor as ligand-dependent ion channel. Nature (1984) 1.58
Chemotactic peptide activation of human neutrophils and HL-60 cells. Pertussis toxin reveals correlation between inositol trisphosphate generation, calcium ion transients, and cellular activation. J Clin Invest (1985) 1.58
Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms. J Clin Invest (1983) 1.54
Phorbol myristate acetate mediates redistribution of protein kinase C in human neutrophils: potential role in the activation of the respiratory burst enzyme. J Immunol (1985) 1.52
Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists. Differential effects of a novel protein kinase inhibitor. J Clin Invest (1986) 1.44
Leukotriene B4 mobilizes calcium without the breakdown of polyphosphoinositides and the production of phosphatidic acid in rabbit neutrophils. Proc Natl Acad Sci U S A (1984) 1.43
Induction of expression and phosphorylation of the human interleukin 2 receptor by a phorbol diester. J Biol Chem (1984) 1.40
Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils with a GTP-binding protein sensitive to pertussis toxin. Proc Natl Acad Sci U S A (1985) 1.39
Hydroxyl radical scavengers inhibit lymphocyte mitogenesis. Proc Natl Acad Sci U S A (1982) 1.36
Phorbol myristate acetate inhibits thrombin-stimulated Ca2+ mobilization and phosphatidylinositol 4,5-bisphosphate hydrolysis in human platelets. Proc Natl Acad Sci U S A (1985) 1.36
Activation of protein kinase C in neutrophil cytoplasts. Localization of protein substrates and possible relationship with stimulus-response coupling. FEBS Lett (1985) 1.35
Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase. Proc Natl Acad Sci U S A (1985) 1.33
Stimulation of human leukocyte degranulation by leukotriene B4 and its omega-oxidized metabolites. FEBS Lett (1981) 1.30
Activation of the human neutrophil nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase by protein kinase C. J Clin Invest (1985) 1.25
Calcium requirements for increased complement receptor expression during neutrophil activation. J Immunol (1985) 1.21
Pertussis toxin inhibits chemotactic factor-induced phospholipase C stimulation and lysosomal enzyme secretion in rabbit neutrophils. FEBS Lett (1985) 1.20
Macrophage colony-stimulating factor (M-CSF) enhances the capacity of murine macrophages to secrete oxygen reduction products. J Immunol (1985) 1.20
Breakdown and synthesis of polyphosphoinositides in fMetLeuPhe-stimulated neutrophils. FEBS Lett (1985) 1.18
Modulation of Ca2+-activated, phospholipid-dependent protein kinase in platelets treated with a tumor-promoting phorbol ester. Biochem Biophys Res Commun (1984) 1.15
Phospholipid-sensitive Ca2+-dependent protein kinase and its substrates in human neutrophils. Biochem Biophys Res Commun (1983) 1.15
Variations on the theme of chronic granulomatous disease. Lancet (1985) 1.12
Platelet activation--a role for a 40K anti-phospholipase A2 protein indistinguishable from lipocortin. Nature (1986) 1.11
Co-activation of protein kinase C and NADPH oxidase in the plasma membrane of neutrophil cytoplasts. Biochem Biophys Res Commun (1986) 1.11
A pertussis toxin-sensitive GTP-binding protein in the human neutrophil regulates multiple receptors, calcium mobilization, and lectin-induced capping. Proc Natl Acad Sci U S A (1985) 1.09
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase. J Biol Chem (1986) 1.09
Desensitization of macrophages to stimuli which induce secretion of superoxide anion. Down-regulation of receptors for phorbol myristate acetate. Eur J Immunol (1983) 1.09
Cytochrome b translocation to human neutrophil plasma membranes and superoxide release. Differential effects of N-formylmethionylleucylphenylalanine, phorbol myristate acetate, and A23187. J Biol Chem (1985) 1.08
Redistribution of protein kinase C activity in human monocytes: correlation with activation of the respiratory burst. J Immunol (1985) 1.06
Use of fluoride ion as a probe for the guanine nucleotide-binding protein involved in the phosphoinositide-dependent neutrophil transduction pathway. FEBS Lett (1986) 1.05
Mechanism of phorbol diester-induced regulation of surface transferrin receptor involves the action of activated protein kinase C and an intact cytoskeleton. J Biol Chem (1985) 1.04
Inositol 1,4,5-trisphosphate may be a signal for f-Met-Leu-Phe-induced intracellular Ca mobilisation in human leucocytes (HL-60 cells). FEBS Lett (1984) 1.03
Activation of murine macrophage cell lines. Possible involvement of protein kinases in stimulation of superoxide production. J Immunol (1984) 1.01
Biochemical signal transmitted by Fc gamma receptors: phospholipase A2 activity of Fc gamma 2b receptor of murine macrophage cell line P388D1. Proc Natl Acad Sci U S A (1982) 0.97
Phospholipid and Ca++ dependency of phorbol ester receptors. J Cell Biochem (1985) 0.96
Platelet Ca2+-activated, phospholipid-dependent protein kinase: evidence for proteolytic activation of the enzyme in cells treated with phospholipase C1. Biochem Biophys Res Commun (1984) 0.94
A step sensitive to pertussis toxin and phorbol ester in human neutrophils regulates chemotaxis and capping but not phagocytosis. FEBS Lett (1986) 0.93
The protein kinase C inhibitors H-7 and H-9 fail to inhibit human neutrophil activation. Biochem Biophys Res Commun (1986) 0.91
Oxidized N-formylmethionyl-leucyl-phenylalanine: effect on the activation of human monocyte and neutrophil chemotaxis and superoxide production. J Immunol (1984) 0.90
Chemiluminescence of polymorphonuclear leukocytes from rheumatoid joints. J Rheumatol (1983) 0.89
Role of enhanced inositol phospholipid metabolism in neutrophil activation. Biochem Pharmacol (1985) 0.87
Stoichiometric binding of diacylglycerol to the phorbol ester receptor. J Cell Biochem (1985) 0.86
Studies of the effect of D-penicillamine and sodium aurothiomalate therapy on superoxide anion production by monocytes from patients with rheumatoid arthritis: evidence for in vivo stimulation of monocytes. Ann Rheum Dis (1986) 0.84
Studies of cytochrome b-245 translocation in the PMA stimulation of the human neutrophil NADPH-oxidase. J Immunol (1985) 0.82
Phorbol ester effect in platelets, lymphocytes, and leukemic cells (HL-60) is associated with enhanced phosphorylation of class I HLA antigens. Coprecipitation of myosin light chain. Biochem Biophys Res Commun (1985) 0.81
Treatment of rabbit neutrophils with phorbol esters results in increased ADP-ribosylation catalyzed by pertussis toxin and inhibition of the GTPase stimulated by fMet-Leu-Phe. FEBS Lett (1986) 0.80
Non-secretion of ABO blood group antigens as a host susceptibility factor in the spondyloarthropathies. Br Med J (Clin Res Ed) (1987) 1.91
Bronchodilatation after inhalation of the antihistamine clemastine. Thorax (1978) 1.76
Health economics as an aspect of health outcome: basic principles and application in rheumatoid arthritis. Br J Rheumatol (1995) 1.43
Measuring health status in British patients with rheumatoid arthritis: reliability, validity and responsiveness of the short form 36-item health survey (SF-36). Br J Rheumatol (1998) 1.38
Is day care equivalent to inpatient care for active rheumatoid arthritis? Randomised controlled clinical and economic evaluation. BMJ (1998) 1.35
Depression of lymphocyte responses after surgical trauma. Br J Exp Pathol (1973) 1.29
Translocation of protein kinase C to a Triton-insoluble sub-cellular compartment induced by the lipophilic gold compound auranofin. Biochem Pharmacol (1988) 1.06
Uptake of chloroquine and hydroxychloroquine by human blood leucocytes in vitro: relation to cellular concentrations during antirheumatic therapy. Ann Rheum Dis (1987) 1.02
Modulation by phorbol myristate acetate of arachidonic acid release and leukotriene synthesis by human polymorphonuclear leukocytes stimulated with A23187. Biochem Biophys Res Commun (1986) 1.00
Zinc increases phorbol ester receptors in intact B-cells, neutrophil polymorphs and platelets. FEBS Lett (1989) 0.98
Evidence for defect of complement-mediated phagocytosis by monocytes from patients with rheumatoid arthritis and cutaneous vasculitis. Br Med J (Clin Res Ed) (1981) 0.94
Is chronic renal failure a risk factor for the development of erosive osteoarthritis? Ann Rheum Dis (1989) 0.93
Coxsackie B infection and arthritis. Br Med J (Clin Res Ed) (1983) 0.93
Differential effects of mepacrine, chloroquine and hydroxychloroquine on superoxide anion generation, phospholipid methylation and arachidonic acid release by human blood monocytes. Biochem Pharmacol (1986) 0.92
A pilot study of the economic cost and clinical outcome of day patient vs inpatient management of active rheumatoid arthritis. Br J Rheumatol (1994) 0.86
Functional defects of monocyte C3b receptor-mediated phagocytosis in rheumatoid arthritis (RA): evidence for an association with the appearance of a circulating population of non-specific esterase-negative mononuclear phagocytes. Ann Rheum Dis (1983) 0.85
Wegener's granulomatosis complicated by diabetes insipidus. Ann Rheum Dis (1983) 0.84
Studies of the effect of D-penicillamine and sodium aurothiomalate therapy on superoxide anion production by monocytes from patients with rheumatoid arthritis: evidence for in vivo stimulation of monocytes. Ann Rheum Dis (1986) 0.84
Evidence for intrinsic cellular defects of 'complement' receptor-mediated phagocytosis in patients with systemic lupus erythematosus (SLE). Clin Exp Immunol (1984) 0.84
Inhibition of epidermal growth factor binding to HeLa cells by auranofin. Biochem Pharmacol (1987) 0.83
Calcium ionophore A23187 enhances human neutrophil superoxide release, stimulated by phorbol dibutyrate, by converting phorbol ester receptors from a low- to high-affinity state. FEBS Lett (1987) 0.83
Medically unexplained symptoms in patients referred to a specialist rheumatology service: prevalence and associations. Rheumatology (Oxford) (2003) 0.82
Quantifying the burden of emotional ill-health amongst patients referred to a specialist rheumatology service. Rheumatology (Oxford) (2003) 0.81
Monocyte superoxide anion production in rheumatoid arthritis: preliminary evidence for enhanced rates of superoxide anion production by monocytes from patients receiving penicillamine, sodium aurothiomalate and corticosteroids. Ann Rheum Dis (1984) 0.81
Auranofin stimulates LTA hydrolase and inhibits 5-lipoxygenase/LTA synthase activity of isolated human neutrophils. Biochem Pharmacol (1990) 0.81
An audit of methotrexate and folic acid for rheumatoid arthritis. Experience from a teaching centre. Br J Rheumatol (1995) 0.81
Cervical spine surgery in patients with rheumatoid arthritis: an appraisal. Ann Rheum Dis (1996) 0.81
IgG (kappa) paraproteinaemia and arthritis. Br J Rheumatol (1987) 0.80
An evaluation of the Health Assessment Questionnaire (HAQ) in a long-term longitudinal follow-up of disability in rheumatoid arthritis. Br J Rheumatol (1994) 0.80
Transient presence in serum of an atypical alkaline phosphatase. Clin Chim Acta (1976) 0.78
Effects of piroxicam on superoxide generation, phospholipid methylation and leukotriene production by human blood mononuclear cells. J Rheumatol (1987) 0.78
Inhibition of protein kinase C activity by the antirheumatic drug auranofin. Biochem Pharmacol (1989) 0.78
Enhancement of protein kinase C-mediated EGF receptor phosphorylation by auranofin. Scand J Rheumatol (1988) 0.78
Premature development of erosive osteoarthritis of hands in patients with chronic renal failure. Ann Rheum Dis (1990) 0.77
Re: Quality of life measures. Br J Rheumatol (1997) 0.77
Sjögren's syndrome, vasculitis, and cryoglobulinaemia associated with a monoclonal IgM (kappa) paraprotein with rheumatoid factor activity. Ann Rheum Dis (1987) 0.77
Auranofin increases the affinity of phorbol dibutyrate receptors in chronic lymphocytic leukemia cells (B cells). J Immunol (1987) 0.76
Reactive arthritis--infectious agents and genetic susceptibility in the pathogenesis of sero-negative arthritis. Scott Med J (1983) 0.76
Does economic evaluation have anything to offer the rheumatologist? Rheumatology (Oxford) (1999) 0.76
Re: Measuring outcomes in rheumatoid arthritis--which measures are suitable for routine use? Br J Rheumatol (1997) 0.75
Screening for antimalarial maculopathy in rheumatology clinics. Br Med J (Clin Res Ed) (1985) 0.75
Sclerosing injections in patients with chronic low back pain. Rheumatology (Oxford) (2000) 0.75
Combination therapy in rheumatoid arthritis. Rheumatology (Oxford) (1999) 0.75
Diagnostic criteria for work-related upper limb disorders. Br J Rheumatol (1997) 0.75
Modulation of human neutrophil LTA hydrolase activity by phorbol myristate acetate. Biochem Biophys Res Commun (1987) 0.75
Vasculitis, Raynaud's phenomenon and polyarthritis associated with gemfibrozil therapy. Br J Rheumatol (1993) 0.75
The effects of anti-inflammatory and anti-rheumatic drugs on phagocyte cell function. Agents Actions Suppl (1988) 0.75
Erdheim-Chester disease associated with hydrocalycosis and arthropathy. Arthritis Rheum (1988) 0.75
Destructive spondylarthropathy and chronic renal failure. Arthritis Rheum (1988) 0.75
Calcium ionophore A23187 primes human B-cells for activation by phorbol dibutyrate by converting receptors for phorbol dibutyrate from a low to high affinity state. Biochem Biophys Res Commun (1986) 0.75
Effect of corticosteroid therapy on blood monocyte superoxide generation in rheumatoid arthritis: studies in vitro and ex vivo. Br J Rheumatol (1986) 0.75
Phorbol 12-myristate 13-acetate, A23187 and L-adrenaline inhibit phospholipid methylation in human monocytes and lymphocytes. Inhibition is independent of oxyradical production and phospholipid hydrolysis. Free Radic Biol Med (1990) 0.75
Auranofin enhances phosphorylation of putative substrates of protein kinase C in human platelets. Biochem Pharmacol (1988) 0.75