Structural determinants of the oxygen reactivity of different classes of flavoproteins.

PubWeight™: 0.82‹?›

🔗 View Article (PMID 3043458)

Published in Prog Clin Biol Res on January 01, 1988

Authors

V Massey1, L M Schopfer, R F Anderson

Author Affiliations

1: Department of Biological Chemistry, University of Michigan, Ann Arbor 48109.

Articles by these authors

(truncated to the top 100)

Activation of molecular oxygen by flavins and flavoproteins. J Biol Chem (1994) 3.73

The last glacial termination. Science (2010) 2.61

Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication. J Biol Chem (2000) 1.64

Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase. Biochemistry (1997) 1.59

Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse. J Neurochem (2000) 1.44

Glucose oxidase from Aspergillus niger. Cloning, gene sequence, secretion from Saccharomyces cerevisiae and kinetic analysis of a yeast-derived enzyme. J Biol Chem (1990) 1.40

Two modes of change in Southern Ocean productivity over the past million years. Science (2013) 1.36

Myocardial toxicity from carbon monoxide poisoning. Ann Intern Med (1967) 1.15

Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality. J Pharmacol Exp Ther (2001) 1.13

Energetics of the one-electron reduction steps of riboflavin, FMN and FAD to their fully reduced forms. Biochim Biophys Acta (1983) 1.11

Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities. Biochemistry (1999) 1.06

Polymer-Producing Species of Arthrobacter. J Bacteriol (1965) 1.06

On the active site of liver acetyl-CoA. Arylamine N-acetyltransferase from rapid acetylator rabbits (III/J). J Biol Chem (1988) 1.04

Results of hyperthermic perfusion for melanoma of the extremities. Surg Gynecol Obstet (1975) 1.03

Two methods for isolating the lung area of a CT scan for density information. Radiology (1982) 1.00

Radiosensitization of Serratia marcescens by bipyridinium compounds. Int J Radiat Biol Relat Stud Phys Chem Med (1977) 0.97

Structure and oxidation-reduction behavior of 1-deaza-FMN flavodoxins: modulation of redox potentials in flavodoxins. Biochemistry (1990) 0.97

Bis(dialkyl)dithiocarbamato cobalt(III) complexes of bidentate nitrogen mustards: synthesis, reduction chemistry and biological evaluation as hypoxia-selective cytotoxins. Anticancer Drug Des (1998) 0.97

Production of Fumaric Acid in 20-Liter Fermentors. Appl Microbiol (1962) 0.96

NLA-1: a 2-nitroimidazole radiosensitizer targeted to DNA by intercalation. Int J Radiat Oncol Biol Phys (1992) 0.96

Reactivity of old yellow enzyme with alpha-NADPH and other pyridine nucleotide derivatives. J Biol Chem (1986) 0.96

Absolute stereochemistry of flavins in enzyme-catalyzed reactions. Biochemistry (1986) 0.94

The active site of human paraoxonase (PON1). J Appl Toxicol (2001) 0.94

Hypoxia-selective antitumor agents. 12. Nitrobenzyl quaternary salts as bioreductive prodrugs of the alkylating agent mechlorethamine. J Med Chem (1996) 0.93

Interflavin oxidation-reduction reactions between pig kidney general acyl-CoA dehydrogenase and electron-transferring flavoprotein. Biochemistry (1985) 0.92

Eleven years' experience with hyperthermic perfusion for melanoma of the extremities. World J Surg (1979) 0.92

Differences in protein structure of xanthine dehydrogenase and xanthine oxidase revealed by reconstitution with flavin active site probes. J Biol Chem (1989) 0.91

Radiosensitization of mammalian cells in vitro by nitroacridines. Radiat Res (1990) 0.90

Results of eleven years' experience with heated perfusion for melanoma of the extremities. Cancer Res (1979) 0.89

Active site probes of flavoproteins. Determination of the solvent accessibility of the flavin position 8 for a series of flavoproteins. J Biol Chem (1981) 0.87

Effect of lipophilicity of nitroimidazoles on radiosensitization of hypoxic bacterial cells in vitro. Br J Cancer (1979) 0.87

Kinetic evidence for ternary complex formation and allosteric interactions in chloride and stilbenedisulfonate binding to band 3. Biochemistry (1994) 0.86

The reactivity of chicken liver xanthine dehydrogenase with molecular oxygen. J Biol Chem (1989) 0.85

Determination of glucose oxidase oxidation-reduction potentials and the oxygen reactivity of fully reduced and semiquinoid forms. J Biol Chem (1978) 0.85

Coupled electron/proton transfer in complex flavoproteins: solvent kinetic isotope effect studies of electron transfer in xanthine oxidase and trimethylamine dehydrogenase. J Biol Chem (2001) 0.85

On the mechanism of radiation-induced emesis: the role of serotonin. Int J Radiat Oncol Biol Phys (1994) 0.85

Radiosensitization by non-nitro compounds. Int J Radiat Oncol Biol Phys (1982) 0.85

A comparison of epicardial and transvenous pacemaker experience. Angiology (1968) 0.84

Pulse radiolysis studies indicate that electron transfer is involved in radioprotection by Hoechst 33342 and methylproamine. Int J Radiat Oncol Biol Phys (1998) 0.84

Determination of the DNA sequences of acetylcholinesterase and butyrylcholinesterase from cat and demonstration of the existence of both in cat plasma. Biochem Pharmacol (2000) 0.83

Calorimetric evidence for allosteric subunit interactions associated with inhibitor binding to band 3 transporter. J Biol Chem (1994) 0.83

Glacial surface temperatures of the southeast Atlantic Ocean. Science (2001) 0.82

The kinetic mechanism of beef kidney D-aspartate oxidase. J Biol Chem (1988) 0.82

Pyridoxal 5'-phosphate binds specifically to soluble CD4 protein, the HIV-1 receptor. Implications for AIDS therapy. J Biol Chem (1993) 0.82

Hypoxia-selective antitumor agents. 1. Relationships between structure, redox properties and hypoxia-selective cytotoxicity for 4-substituted derivatives of nitracrine. J Med Chem (1989) 0.81

The radical chemistry of milk xanthine oxidase as studied by radiation chemistry techniques. J Biol Chem (1986) 0.81

Oxidative metabolism of amsacrine by the neutrophil enzyme myeloperoxidase. Biochem Pharmacol (1992) 0.81

Interactions between mutant and wild-type band 3 subunits in hereditary Southeast Asian ovalocytic red blood cell membranes. Biochemistry (1996) 0.81

Energetics of the one-electron steps in the NAD+/NADH redox couple. Biochim Biophys Acta (1980) 0.81

Reactivity of chicken liver xanthine dehydrogenase containing modified flavins. J Biol Chem (1989) 0.81

Resonance Raman spectra of flavin derivatives containing chemical modifications in positions 7 and 8 of the isoalloxazine ring. Biochemistry (1980) 0.81

Kinetics of conformational changes associated with inhibitor binding to the purified band 3 transporter. Direct observation of allosteric subunit interactions. Biochemistry (1993) 0.81

Nasopharyngeal carcinoma: the Dana-Farber Cancer Institute experience with 24 patients treated with induction chemotherapy and radiotherapy. Ann Otol Rhinol Laryngol (1987) 0.81

Kinetic mechanism of DIDS binding to band 3 (AE1) in human erythrocyte membranes. Blood Cells Mol Dis (2002) 0.80

Studies of the flavin adenine dinucleotide binding region in Escherichia coli pyruvate oxidase. J Biol Chem (1982) 0.80

Electron transfer in milk xanthine oxidase as studied by pulse radiolysis. J Biol Chem (1991) 0.80

Differential sensitivity of stilbenedisulfonates in their reaction with band 3 HT (Pro-868-->Leu). Proc Natl Acad Sci U S A (1995) 0.80

Kinetic and mechanistic studies on the reaction of melilotate hydroxylase with deuterated melilotate. Biochemistry (1975) 0.80

Radiation-activated prodrugs as hypoxia-selective cytotoxins: model studies with nitroarylmethyl quaternary salts. Anticancer Drug Des (1998) 0.79

Comparative bioactivation of the novel anti-tuberculosis agent PA-824 in Mycobacteria and a subcellular fraction of human liver. Br J Pharmacol (2011) 0.79

Hypoxia-selective antitumor agents. 6. 4-(Alkylamino)nitroquinolines: a new class of hypoxia-selective cytotoxins. J Med Chem (1992) 0.79

Kinetics of heat inactivation of phenyl valerate hydrolases from hen and rat brain. Biochem Pharmacol (1987) 0.79

Kinetic and mechanistic studies on the oxidation of the melilotate hydroxylase . 2-OH-cinnamate complex by molecular oxygen. J Biol Chem (1980) 0.79

Hypoxia-selective antitumor agents. 15. Modification of rate of nitroreduction and extent of lysosomal uptake by polysubstitution of 4-(alkylamino)-5-nitroquinoline bioreductive drugs. J Med Chem (1997) 0.78

Use of riboflavin-binding protein to investigate steric and electronic relationships in flavin analogs and models. Proc Natl Acad Sci U S A (1984) 0.78

Temporal trends of cancer mortality in eastern New England compared to the nation, 1950-1975. Soc Sci Med (1984) 0.78

Radiosensitization of hypoxic bacterial cells by nitroimidazoles of low lipophilicity: steady-state and rapid-mix studies. Radiat Res (1981) 0.78

2-Thioflavins as active site probes of flavoproteins. J Biol Chem (1982) 0.78

Inhibition of gp120-CD4 interaction and human immunodeficiency virus type 1 infection in vitro by pyridoxal 5'-phosphate. Antimicrob Agents Chemother (1994) 0.77

Soft tissue sarcomas of the extremity. Multidisciplinary therapy employing hyperthermic perfusion. Am J Surg (1975) 0.77

pH dependence of the reoxidation of p-hydroxybenzoate hydroxylase 2,4-dihydroxybenzoate complex. J Biol Chem (1984) 0.77

Tryptophan residue(s) as major components of the human serum paraoxonase active site. Chem Biol Interact (1999) 0.77

Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives. J Med Chem (1989) 0.76

Inhibition of radical-induced DNA strand breaks by water-soluble constituents of coffee: phenolics and caffeine metabolites. Free Radic Res (2013) 0.76

Reactions of 1-deaza-FAD-substituted phenol hydroxylase and melilotate hydroxylase. J Biol Chem (1984) 0.76

Chemotherapeutic strategies in the multidisciplinary treatment of head and neck cancer. Semin Oncol (1988) 0.75

Hypoxia-selective antitumor agents. 16. Nitroarylmethyl quaternary salts as bioreductive prodrugs of the alkylating agent mechlorethamine. J Med Chem (2001) 0.75

Radiosensitization of Serratia marcescens by nitropyridinium compounds. Br J Cancer Suppl (1978) 0.75

Critical residues in D-amino acid oxidase. A pulse-radiolysis and inactivation study. Int J Radiat Biol Relat Stud Phys Chem Med (1977) 0.75

Synthesis and evaluation of 4-substituted analogues of 5-[N,N-bis (2-chloroethyl)amino]-2-nitrobenzamide as bioreductively activated prodrugs using an Escherichia coli nitroreductase. Anticancer Drug Des (1996) 0.75

Characterization of the stilbenedisulphonate binding site on band 3 Memphis variant II (Pro-854-->Leu). Biochem J (1996) 0.75

Resonance Raman spectra for flavin derivatives modified in the 8 position. Biochemistry (1981) 0.75

Kinetic and mechanistic studies on the reduction of melilotate hydroxylase by reduced pyridine nucleotides. J Biol Chem (1979) 0.75

Primary closure of infected diabetic foot wounds. A report of closed instillation in 30 cases. J Am Podiatr Med Assoc (2000) 0.75

Intracellular and extracellular radiosensitization of Serratia marcescens by bipyridinium compounds. Radiat Res (1979) 0.75

Reduction of nitroimidazoles in model chemical and biological systems. Int J Radiat Oncol Biol Phys (1982) 0.75

Characterization of a hybrid hamster-human cell line complemented for the ataxia telangiectasia DNA repair defects. Pathobiology (1994) 0.75

New benzopyrans: anticonvulsant activities. Life Sci (1975) 0.75

Free radical reactions with proteins and enzymes. The inactivation of bovine carbonic anhydrase B. Biochim Biophys Acta (1981) 0.75

Bionomics of the bark beetle predator, Temnochila virescens Mann. (Coleoptera: Ostomidae). Entomol News (1970) 0.75

Metabolic potentiation of the radiosensitization of hypoxic bacterial cells afforded by nitroaromatic compounds. Radiat Res (1983) 0.75

Reduction of nitroarylmethyl quaternary ammonium prodrugs of mechlorethamine by radiation. Radiat Res (1998) 0.75

The effect of 1,4-diazabicyclo[2.2.2.]octane on the radiosensitivity of bacteria. Photochem Photobiol (1979) 0.75

Elevated concentrations of actinides in mono lake. Science (1982) 0.75

Radiation-induced emesis: effects of ondansetron. Semin Oncol (1992) 0.75

The inhibition by anion binding of reactions of inorganic radical anions with bovine carbonic anhydrase B. Biochim Biophys Acta (1981) 0.75

Hypoxia-selective radiosensitization of mammalian cells by nitracrine, an electron-affinic DNA intercalator. Int J Radiat Biol Relat Stud Phys Chem Med (1987) 0.75

Hyperthermic perfusion of extremities for melanoma and soft tissue sarcomas. Recent Results Cancer Res (1977) 0.75

Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide. J Med Chem (1996) 0.75

P-Hydroxybenzoate hydroxylase and melilotate hydroxylase. Methods Enzymol (1978) 0.75