PubRank

J F MacDonald

Author PubWeight™ 100.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons. Neuron 2001 5.51
2 Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science 1999 3.23
3 Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons. Mol Pharmacol 2001 2.43
4 Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones. J Physiol 1992 2.35
5 CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus. Neuron 2001 2.22
6 Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin. Nature 1997 2.16
7 The general anesthetic propofol slows deactivation and desensitization of GABA(A) receptors. J Neurosci 1999 1.83
8 G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors. Nat Neurosci 1999 1.76
9 Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases. Science 1991 1.66
10 Phosphorylation and modulation of a kainate receptor (GluR6) by cAMP-dependent protein kinase. Science 1993 1.55
11 Ketamine and phencyclidine cause a voltage-dependent block of responses to L-aspartic acid. Neurosci Lett 1985 1.53
12 Blockade of glutamate receptors and barbiturate anesthesia: increased sensitivity to pentobarbital-induced anesthesia despite reduced inhibition of AMPA receptors in GluR2 null mutant mice. Anesthesiology 1999 1.51
13 Multiple mechanisms of ketamine blockade of N-methyl-D-aspartate receptors. Anesthesiology 1997 1.42
14 L-Aspartic acid induces a region of negative slope conductance in the current-voltage relationship of cultured spinal cord neurons. Brain Res 1982 1.40
15 Fluctuation analysis of neutral amino acid responses in cultured mouse spinal neurones. J Physiol 1982 1.38
16 Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A. Nature 1994 1.34
17 Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons. J Neurosci 1994 1.31
18 Blockade of AMPA receptors and volatile anesthetics: reduced anesthetic requirements in GluR2 null mutant mice for loss of the righting reflex and antinociception but not minimum alveolar concentration. Anesthesiology 2001 1.27
19 Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity. J Neurosci 2000 1.24
20 NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release. Trends Pharmacol Sci 1995 1.22
21 Extracellular calcium sensed by a novel cation channel in hippocampal neurons. Proc Natl Acad Sci U S A 1997 1.20
22 Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones. Br J Pharmacol 1995 1.19
23 Hydrogen ions have multiple effects on the excitability of cultured mammalian neurons. Brain Res 1980 1.18
24 Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src. J Neurosci 2005 1.18
25 Enhanced calcium transients in glial cells in neonatal cerebellar cultures derived from S100B null mice. Exp Cell Res 2000 1.15
26 Neurotrophin modulation of NMDA receptors in cultured murine and isolated rat neurons. J Neurophysiol 1997 1.08
27 Modulation by magnesium of the affinity of NMDA receptors for glycine in murine hippocampal neurones. J Physiol 1995 1.07
28 Blockade by ifenprodil of high voltage-activated Ca2+ channels in rat and mouse cultured hippocampal pyramidal neurones: comparison with N-methyl-D-aspartate receptor antagonist actions. Br J Pharmacol 1994 1.06
29 N-methyl-D-aspartate receptor-mediated voltage oscillations in neurons surrounding the central canal in slices of rat spinal cord. J Neurophysiol 1994 1.04
30 Ethanol modulation of GABA receptor-activated Cl- currents in neurons of the chick, rat and mouse central nervous system. Eur J Pharmacol 1992 1.03
31 Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition. J Neurosci 1999 1.03
32 Regulation of N-methyl-D-aspartate receptor function by constitutively active protein kinase C. Mol Pharmacol 1998 1.03
33 Modulation of AMPA/kainate receptors in cultured murine hippocampal neurones by protein kinase C. J Physiol 1994 1.02
34 The Lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist. J Biol Chem 2000 1.01
35 The effects of L-glutamate and its analogues upon the membrane conductance of central murine neurones in culture. Can J Physiol Pharmacol 1982 1.01
36 Requirement of NMDA receptor/channels for intracellular high-energy phosphates and the extent of intraneuronal calcium buffering in cultured mouse hippocampal neurons. Neurosci Lett 1988 1.00
37 Loperamide blocks high-voltage-activated calcium channels and N-methyl-D-aspartate-evoked responses in rat and mouse cultured hippocampal pyramidal neurons. Mol Pharmacol 1994 0.99
38 Regulation of NMDA receptor activity by F-actin and myosin light chain kinase. J Neurosci 2001 0.98
39 In CA1 pyramidal neurons of the hippocampus protein kinase C regulates calcium-dependent inactivation of NMDA receptors. J Neurosci 2000 0.96
40 Sensitivity of AMPA receptors to pentobarbital. Eur J Pharmacol 1994 0.95
41 Sensing of extracellular calcium by neurones. Can J Physiol Pharmacol 1999 0.95
42 A transmembrane model for an ionotropic glutamate receptor predicted on the basis of the location of asparagine-linked oligosaccharides. J Biol Chem 1994 0.95
43 A potassium conductance contributes to the action of somatostatin-14 to suppress ACTH secretion. Brain Res 1988 0.94
44 GABA receptor functions in cultured mouse spinal neurons. Adv Biochem Psychopharmacol 1981 0.93
45 A comparison of two alternatively spliced forms of a metabotropic glutamate receptor coupled to phosphoinositide turnover. J Neurochem 1993 0.93
46 Platelet-derived growth factor induces a long-term inhibition of N-methyl-D-aspartate receptor function. J Biol Chem 1996 0.93
47 Haloperidol blocks voltage-activated Ca2+ channels in hippocampal neurones. Eur J Pharmacol 1994 0.93
48 Positive allosteric modulators of AMPA receptors reduce proton-induced receptor desensitization in rat hippocampal neurons. J Neurophysiol 2001 0.92
49 A method for isolating and patch-clamping single mammalian taste receptor cells. Brain Res 1989 0.92
50 DL-quisqualic and L-aspartic acids activate separate excitatory conductances in cultured spinal cord neurons. Brain Res 1982 0.89
51 Substitution of extracellular sodium ions blocks the voltage-dependent decrease of input conductance evoked by L-aspartate. Can J Physiol Pharmacol 1984 0.88
52 A comparison of the action of glutamate, ibotenate and other related amino acids on feline spinal interneurones. J Physiol 1978 0.88
53 L-aspartic acid potentiates 'slow' inward current in cultured spinal cord neurons. Brain Res 1984 0.87
54 Cloning of a G protein-activated inwardly rectifying potassium channel from human cerebellum. Brain Res Mol Brain Res 1996 0.86
55 General anaesthetics and their effects on GABA(A) receptor desensitization. Toxicol Lett 1998 0.86
56 Motoneuronal after-potentials and extracellular divalent cations. Can J Physiol Pharmacol 1978 0.86
57 Effect of lamotrigine on the Ca(2+)-sensing cation current in cultured hippocampal neurons. J Neurophysiol 2001 0.85
58 Prostaglandin F2alpha potentiates cortisol production by stimulating 11beta-hydroxysteroid dehydrogenase 1: a novel feedback loop that may contribute to human labor. J Clin Endocrinol Metab 2001 0.85
59 Platelet-derived growth factor receptor-induced feed-forward inhibition of excitatory transmission between hippocampal pyramidal neurons. J Biol Chem 1999 0.85
60 Cyclic GMP-dependent feedback inhibition of AMPA receptors is independent of PKG. Nat Neurosci 2000 0.85
61 Effects of some divalent cations on motoneurones in cats. Can J Physiol Pharmacol 1979 0.84
62 Two conductance mechanisms activated by applications of L-glutamic, L-aspartic, DL-homocysteic, N-methyl-D-aspartic, and DL-kainic acids to cultured mammalian central neurones. Can J Physiol Pharmacol 1980 0.84
63 Multiple reversal potentials for responses to L-glutamic acid. Brain Res 1981 0.84
64 Frequency-dependent decay of calcium spikes in cultured spinal cord neurons. Neuroscience 1986 0.83
65 Depression of monosynaptic excitatory postsynaptic potentials by Mn2+ and Co2+ in cat spinal cord. Neuroscience 1979 0.83
66 Picrotoxin convulsions involve synaptic and nonsynaptic mechanisms on cultured mouse spinal neurons. Science 1980 0.83
67 Glucocorticoids and serotonin alter glucocorticoid receptor (GR) but not mineralocorticoid receptor (MR) mRNA levels in fetal mouse hippocampal neurons, in vitro. Brain Res 2001 0.82
68 Differential effects of lectins on recombinant glutamate receptors. Eur J Pharmacol 1995 0.82
69 Blockade by sigma site ligands of N-methyl-D-aspartate-evoked responses in rat and mouse cultured hippocampal pyramidal neurones. Br J Pharmacol 1995 0.82
70 Whole-cell voltage-clamp recordings in granule cells acutely isolated from hippocampal slices of adult or aged rats. Neurosci Lett 1989 0.82
71 Expression of functional metabotropic and ionotropic glutamate receptors in baculovirus-infected insect cells. Neurosci Lett 1994 0.81
72 Selective reduction of N-methyl-D-aspartate-evoked responses by 1,3-di(2-tolyl)guanidine in mouse and rat cultured hippocampal pyramidal neurones. Br J Pharmacol 1993 0.81
73 Voltage-dependent block of excitatory amino acid currents by pentobarbital. Brain Res 1986 0.81
74 Lathyrus excitotoxin: mechanism of neuronal excitation by L-2-oxalylamino-3-amino- and L-3-oxalylamino-2-amino-propionic acid. Exp Brain Res 1984 0.80
75 Actions of microiontophoretically applied ibotenate on cat spinal interneurones. Can J Physiol Pharmacol 1977 0.80
76 Multiple sites of action of neomycin, Mg2+ and spermine on the NMDA receptors of rat hippocampal CA1 pyramidal neurones. J Physiol 1998 0.80
77 Changes in intracellular free Ca ion concentration evoked by electrical activity in cat spinal neurons in situ. Neuroscience 1985 0.80
78 Multiple actions of picomolar concentrations of flurazepam on the excitability of cultured mouse spinal neurons. Brain Res 1982 0.79
79 Inosine may be an endogenous ligand for benzodiazepine receptors on cultured spinal neurons. Science 1979 0.79
80 Glucocorticoids and serotonin alter glucocorticoid receptor mRNA levels in fetal guinea-pig hippocampal neurons, in vitro. Reprod Fertil Dev 2005 0.79
81 Intracellular calcium in mammalian brain cells: fluorescence measurements with quin2. Exp Brain Res 1987 0.79
82 Excitatory amino acid blockers differentially affect bursting of in vitro hippocampal neurons in two pharmacological models of epilepsy. Neuroscience 1989 0.78
83 Signals transduced by gamma-aminobutyric acid in cultured central nervous system neurons and thyrotropin releasing hormone in clonal pituitary cells. Ann N Y Acad Sci 1987 0.78
84 Further identification of multiple responses mediated by dopamine in the CNS of Planorbis corneus. Can J Physiol Pharmacol 1978 0.78
85 Haloperidol interacts with the strychnine-insensitive glycine site at the NMDA receptor in cultured mouse hippocampal neurones. Eur J Pharmacol 1993 0.78
86 Isobolographic analysis of the interactions between midazolam and propofol at GABA(A) receptors in embryonic mouse neurons. Anesthesiology 1998 0.77
87 Signal transduction mechanisms in cultured CNS neurons and clonal pituitary cells. Neuropharmacology 1987 0.77
88 Neuronal depressant effects of diethylester derivatives of excitatory amino acids. Can J Physiol Pharmacol 1977 0.77
89 Kindling-induced epilepsy alters calcium currents in granule cells of rat hippocampal slices. Brain Res 1990 0.77
90 Effects of reduced magnesium on hippocampal synchrony. Brain Res 1987 0.76
91 The effect of p-CPA and lesions of the dorsal raphe nucleus on habituation of the flexor withdrawal reflex. Brain Res 1974 0.75
92 Intracellular divalent cations and neuronal excitability. Can J Physiol Pharmacol 1979 0.75
93 Intracellular calcium recordings from isolated cells of the mammalian central nervous system. Can J Physiol Pharmacol 1987 0.75
94 Habituation and sensitization of the flexor reflex after asphyxiation of the spinal cord. Brain Res 1973 0.75
95 Actions of verapamil on the excitability of cultured neurones. Can J Physiol Pharmacol 1983 0.75
96 Black doctors on television. N Y State J Med 1985 0.75
97 Effects of ibotenic acid on amphibian and mammalian spinal neurones in vitro. Adv Biochem Psychopharmacol 1981 0.75
98 Depression by manganese and cobalt of monosynaptic Ia excitatory postsynaptic potential in cat spinal cord [proceedings]. J Physiol 1979 0.75
99 Measurements of transmitter action: the problem of voltage dependence. Can J Physiol Pharmacol 1985 0.75
100 Modulation of AMPA receptors by a novel organic nitrate. Can J Physiol Pharmacol 2001 0.75
101 Peptide receptor functions on cultured spinal neurons. Adv Biochem Psychopharmacol 1980 0.75
102 Habituation of the flexor reflex: inhibitory build-up or synaptic depression? Brain Res 1973 0.75
103 Alteration of neuronal calcium homeostasis and excitotoxic vulnerability by chronic depolarization. Brain Res 1994 0.75
104 Pharmacology of dopamine receptors in the central nervous system of Planorbis corneus [proceedings]. J Physiol 1976 0.75
105 Excitatory amino acids and regenerative activity in cultured neurons. Adv Exp Med Biol 1986 0.75
106 A progressive and cumulative suppression of the activity of spinal neurones in the nonspinal rat. Can J Physiol Pharmacol 1977 0.75
107 Measurements of intracellular free Ca2+ in mammalian central neurons. Can J Physiol Pharmacol 1987 0.75
108 Two distinct inhibitory responses of cultured, mammalian spinal neurones to ibotenic acid. Can J Physiol Pharmacol 1980 0.75
109 Intracellular actions of monoamine transmitters. Can J Physiol Pharmacol 1978 0.75
110 Recruitment of NMDA receptors into synaptic transmission after kindling-induced epilepsy and its possible mechanism. Epilepsy Res Suppl 1992 0.75
111 Gadolinium reduces AMPA receptor desensitization and deactivation in hippocampal neurons. J Neurophysiol 2001 0.75
112 Reconciling differences between in vitro and in vivo effects of propofol. Anesthesiology 1996 0.75